| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deng Wu, Jacquelyne Ka-Li Sun, Kim Hei-Man Cho. Neuronal cell cycle reentry events in the aging brain are more prevalent in neurodegeneration and lead to cellular senescence. PLoS biology. vol 22. issue 4. 2024-04-23. PMID:38652714. |
similarly, these general features of cell cycle re-engaging neurons were also observed in a subpopulation of dopaminergic neurons identified in the parkinson's disease (pd)-lewy body dementia (lbd) model. |
2024-04-23 |
2024-04-26 |
mouse |
| Dario Arnaldi, Pietro Mattioli, Stefano Raffa, Matteo Pardini, Federico Massa, Alex Iranzo, Andres Perissinotti, Aida Niñerola-Baizán, Carles Gaig, Monica Serradell, Amaia Muñoz-Lopetegi, Gerard Mayà, Claudio Liguori, Mariana Fernandes, Fabio Placidi, Agostino Chiaravalloti, Karel Šonka, Petr Dušek, David Zogala, Jiri Trnka, Bradley F Boeve, Toji Miyagawa, Val J Lowe, Tomoyuki Miyamoto, Masayuki Miyamoto, Monica Puligheddu, Michela Figorilli, Alessandra Serra, Michele T Hu, Johannes C Klein, Frederik Bes, Dieter Kunz, Valérie Cochen De Cock, Delphine de Verbizier, Giuseppe Plazzi, Elena Antelmi, Michele Terzaghi, Irene Bossert, Kristína Kulcsárová, Alessio Martino, Alessandro Giuliani, Marco Pagani, Flavio Nobili, Silvia Morbell. Presynaptic Dopaminergic Imaging Characterizes Patients with REM Sleep Behavior Disorder Due to Synucleinopathy. Annals of neurology. 2024-03-11. PMID:38466158. |
to apply a machine learning analysis to clinical and presynaptic dopaminergic imaging data of patients with rapid eye movement (rem) sleep behavior disorder (rbd) to predict the development of parkinson disease (pd) and dementia with lewy bodies (dlb). |
2024-03-11 |
2024-03-14 |
Not clear |
| Helamã Moraes Dos Santos, Amanda Gollo Bertollo, Maiqueli Eduarda Dama Mingoti, Roberta Eduarda Grolli, Kelli Maria Kreuz, Zuleide Maria Ignáci. Dementia and depression: Biological connections with amyloid β protein. Basic & clinical pharmacology & toxicology. 2024-03-09. PMID:38459754. |
small extracellular senile plaques composed of filamentous aggregates of amyloid β (aβ) protein tend to bind to neuronal receptors, affecting cholinergic, serotonergic, dopaminergic and noradrenergic neurotransmission, leading to neuroinflammation, among other pathophysiologic processes and subsequent neuronal death, followed by dementia. |
2024-03-09 |
2024-03-11 |
Not clear |
| Anna Stockbauer, Leonie Beyer, Maria Huber, Annika Kreuzer, Carla Palleis, Sabrina Katzdobler, Boris-Stephan Rauchmann, Silvia Morbelli, Andrea Chincarini, Rose Bruffaerts, Rik Vandenberghe, Milica G Kramberger, Maja Trost, Valentina Garibotto, Nicolas Nicastro, Aurélien Lathuilière, Afina W Lemstra, Bart N M van Berckel, Andrea Pilotto, Alessandro Padovani, Miguel A Ochoa-Figueroa, Anette Davidsson, Valle Camacho, Enrico Peira, Matteo Bauckneht, Matteo Pardini, Gianmario Sambuceti, Dag Aarsland, Flavio Nobili, Mattes Gross, Jonathan Vöglein, Robert Perneczky, Oliver Pogarell, Katharina Buerger, Nicolai Franzmeier, Adrian Danek, Johannes Levin, Günter U Höglinger, Peter Bartenstein, Paul Cumming, Axel Rominger, Matthias Brende. Metabolic network alterations as a supportive biomarker in dementia with Lewy bodies with preserved dopamine transmission. European journal of nuclear medicine and molecular imaging. 2023-11-16. PMID:37971501. |
the goals of this study were (i) to evaluate pattern similarities of glucose metabolism and network connectivity in dementia with lewy bodies (dlb) subjects with subthreshold dopaminergic loss compared to advanced disease stages and to (ii) investigate metabolic network alterations of fdg-pet for discrimination of patients with early dlb from other neurodegenerative disorders (alzheimer's disease, parkinson's disease, multiple system atrophy) at individual patient level via principal component analysis (pca). |
2023-11-16 |
2023-11-20 |
human |
| Young-Gun Lee, Seun Jeon, Sung Woo Kang, Byoung Seok Y. Effects of amyloid beta and dopaminergic depletion on perfusion and clinical symptoms. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-07-08. PMID:37422287. |
although mixed pathologies are common in alzheimer's disease (ad) and dementia with lewy bodies (dlb), the effects of amyloid beta and dopaminergic depletion on brain perfusion and clinical symptoms have not been elucidated. |
2023-07-08 |
2023-08-14 |
Not clear |
| Young-Gun Lee, Seun Jeon, Kyoungwon Baik, Sung Woo Kang, Byoung Seok Y. Substantia nigral dopamine transporter uptake in dementia with Lewy bodies. NPJ Parkinson's disease. vol 9. issue 1. 2023-06-11. PMID:37296236. |
nigrostriatal dopaminergic degeneration is a pathological hallmark of dementia with lewy bodies (dlb). |
2023-06-11 |
2023-08-14 |
Not clear |
| Tatyana Dmitrievna Fedorova, Karoline Knudsen, Jacob Horsager, Allan K Hansen, Niels Okkels, Hanne Gottrup, Kim Vang, Per Borghamme. Dopaminergic Dysfunction Is More Symmetric in Dementia with Lewy Bodies Compared to Parkinson's Disease. Journal of Parkinson's disease. 2023-05-22. PMID:37212074. |
dopaminergic dysfunction is more symmetric in dementia with lewy bodies compared to parkinson's disease. |
2023-05-22 |
2023-08-14 |
Not clear |
| Masato Okitsu, Keizo Sugaya, Yasuhiro Nakata, Tomoya Kawazoe, Jun Ikezawa, Ryoichi Okiyama, Kazushi Takahash. Degeneration of nigrostriatal dopaminergic neurons in the early to intermediate stage of dementia with Lewy bodies and Parkinson's disease. Journal of the neurological sciences. vol 449. 2023-04-21. PMID:37084522. |
degeneration of nigrostriatal dopaminergic neurons in the early to intermediate stage of dementia with lewy bodies and parkinson's disease. |
2023-04-21 |
2023-08-14 |
Not clear |
| Mario Jreige, George K Kurian, Jérémy Perriraz, Jevita Potheegadoo, Fosco Bernasconi, Sara Stampacchia, Olaf Blanke, Griffa Alessandra, Noemie Lejay, Paolo Salvioni Chiabotti, Olivier Rouaud, Marie Nicod Lalonde, Niklaus Schaefer, Giorgio Treglia, Gilles Allali, John O Prio. The diagnostic performance of functional dopaminergic scintigraphic imaging in the diagnosis of dementia with Lewy bodies: an updated systematic review. European journal of nuclear medicine and molecular imaging. 2023-03-15. PMID:36920494. |
the diagnostic performance of functional dopaminergic scintigraphic imaging in the diagnosis of dementia with lewy bodies: an updated systematic review. |
2023-03-15 |
2023-08-14 |
Not clear |
| Mario Jreige, George K Kurian, Jérémy Perriraz, Jevita Potheegadoo, Fosco Bernasconi, Sara Stampacchia, Olaf Blanke, Griffa Alessandra, Noemie Lejay, Paolo Salvioni Chiabotti, Olivier Rouaud, Marie Nicod Lalonde, Niklaus Schaefer, Giorgio Treglia, Gilles Allali, John O Prio. The diagnostic performance of functional dopaminergic scintigraphic imaging in the diagnosis of dementia with Lewy bodies: an updated systematic review. European journal of nuclear medicine and molecular imaging. 2023-03-15. PMID:36920494. |
dopaminergic scintigraphic imaging is a cornerstone to support the diagnosis in dementia with lewy bodies. |
2023-03-15 |
2023-08-14 |
Not clear |
| Silvia Paola Caminiti, Andrea Pilotto, Enrico Premi, Alice Galli, Elisabetta Ferrari, Stefano Gipponi, Elisabetta Cottini, Barbara Paghera, Daniela Perani, Alessandro Padovan. Dopaminergic connectivity reconfiguration in the dementia with Lewy bodies continuum. Parkinsonism & related disorders. vol 108. 2023-02-01. PMID:36724569. |
dopaminergic connectivity reconfiguration in the dementia with lewy bodies continuum. |
2023-02-01 |
2023-08-14 |
Not clear |
| Silvia Paola Caminiti, Andrea Pilotto, Enrico Premi, Alice Galli, Elisabetta Ferrari, Stefano Gipponi, Elisabetta Cottini, Barbara Paghera, Daniela Perani, Alessandro Padovan. Dopaminergic connectivity reconfiguration in the dementia with Lewy bodies continuum. Parkinsonism & related disorders. vol 108. 2023-02-01. PMID:36724569. |
the impairment of nigrostriatal dopaminergic network is a core feature of dementia with lewy bodies (dlb). |
2023-02-01 |
2023-08-14 |
Not clear |
| Esen Saka Topçuoğlu, Ümit Özgür Akdemir, Lütfiye Özlem Ata. What is New in Nuclear Medicine Imaging for Dementia. Noro psikiyatri arsivi. vol 59. issue Suppl 1. 2022-12-29. PMID:36578980. |
amyloid positron emission tomography (pet) and tau pet, which are molecular imaging methods, [f18]fluorodeoxyglucose (fdg) pet showing the glucose metabolism pattern in the brain, dopamine transporter single photon emission computerized tomography (spect) that marks dopaminergic terminals are valuable tools for early recognition and differentiation of ad and its atypical variants, frontotemporal dementias and dementia with lewy bodies. |
2022-12-29 |
2023-08-14 |
Not clear |
| Elon D Wallert, Elsmarieke van de Giessen, Remco J J Knol, Martijn Beudel, Rob M A de Bie, Jan Booi. Imaging Dopaminergic Neurotransmission in Neurodegenerative Disorders. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 63. issue Suppl 1. 2022-06-01. PMID:35649651. |
imaging of dopaminergic transmission in neurodegenerative disorders such as parkinson disease (pd) or dementia with lewy bodies plays a major role in clinical practice and in clinical research. |
2022-06-01 |
2023-08-13 |
Not clear |
| Margherita Fabbri, Miguel Coelho, Michela Garon, Roberta Biundo, Tiago A Mestre, Angelo Antonini, On Behalf Of iCARE-Pd Consortiu. Personalized Care in Late-Stage Parkinson's Disease: Challenges and Opportunities. Journal of personalized medicine. vol 12. issue 5. 2022-05-28. PMID:35629235. |
the clinical presentation in lspd is dominated by motor and non-motor symptoms (nms) that most of the time have a sub-optimal to no response to dopaminergic treatment, especially when dementia is present. |
2022-05-28 |
2023-08-13 |
Not clear |
| Kristi Henjum, Leiv Otto Watne, Kristin Godang, Nathalie Bodd Halaas, Rannveig Saksholm Eldholm, Kaj Blennow, Henrik Zetterberg, Ingvild Saltvedt, Jens Bollerslev, Anne Brita Knapsko. Cerebrospinal fluid catecholamines in Alzheimer's disease patients with and without biological disease. Translational psychiatry. vol 12. issue 1. 2022-04-10. PMID:35397615. |
noradrenergic and dopaminergic neurons are involved in cognitive functions, relate to behavioral and psychological symptoms in dementia and are affected in alzheimer's disease (ad). |
2022-04-10 |
2023-08-13 |
Not clear |
| Pao-Hui Tseng, Li-Kung Wu, Yi-Cheng Wang, Tsung-Jung Ho, Shinn-Zong Lin, Sheng-Tzung Tsa. Diagnosis and treatment for normal pressure hydrocephalus: From biomarkers identification to outcome improvement with combination therapy. Tzu chi medical journal. vol 34. issue 1. 2022-03-02. PMID:35233354. |
recent studies demonstrated that the pathophysiology of inph may include both preceding cerebrovascular events and concomitant alzheimer's dementia or dopaminergic degenerative neuropathology in patients' brain. |
2022-03-02 |
2023-08-13 |
Not clear |
| Han Soo Yoo, Seong Ho Jeong, Kyeong Taek Oh, Sangwon Lee, Young H Sohn, Byoung Seok Ye, Mijin Yun, Phil Hyu Le. Interrelation of striatal dopamine, brain metabolism and cognition in dementia with Lewy bodies. Brain : a journal of neurology. 2022-03-02. PMID:35234856. |
our findings suggest that in dementia with lewy bodies, striatal dopaminergic depletion and brain hypometabolism are closely related, and they differentially affect cognitive dysfunction in an item-specific manner. |
2022-03-02 |
2023-08-13 |
human |
| Narmadhaa Sivagurunathan, Aghil T S Ambatt, Latchoumycandane Calivaratha. Role of Long Non-Coding RNAs in the Pathogenesis of Alzheimer's and Parkinson's diseases. Current aging science. 2022-01-27. PMID:35081899. |
ad is a neurological condition that leads to dementia and cognitive decline due to neuronal cell death in the brain, whereas pd is a movement disorder affecting neuro-motor function and is developed due to the death of the dopaminergic neurons in the brain which results in decreased dopamine levels. |
2022-01-27 |
2023-08-13 |
Not clear |
| Maximilian Wulf, Katalin Barkovits-Boeddinghaus, Paula Sommer, Karin Schork, Martin Eisenacher, Peter Riederer, Manfred Gerlach, Steffen Kösters, Britta Eggers, Katrin Marcu. Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules. Journal of visualized experiments : JoVE. issue 178. 2022-01-03. PMID:34978295. |
although nmgs-containing dopaminergic neurons are preferentially lost in neurodegenerative diseases like parkinson's disease and dementia with lewy bodies, only little is known about the mechanism of nmg formation and the role of nmgs in health and disease. |
2022-01-03 |
2023-08-13 |
human |