| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolas Nicastro, Umberto Nencha, Pierre R Burkhard, Valentina Garibott. Dopaminergic imaging in degenerative parkinsonisms, an established clinical diagnostic tool. Journal of neurochemistry. 2021-12-22. PMID:34935143. |
with the present study, we aimed at summarizing the current evidence about dopaminergic molecular imaging in the diagnostic evaluation of pd, atypical parkinsonian syndromes and dementia with lewy bodies (dlb), as well as its potential to distinguish these conditions and to estimate disease progression. |
2021-12-22 |
2023-08-13 |
human |
| Tun-Wei Hsu, Jong-Ling Fuh, Da-Wei Wang, Li-Fen Chen, Chia-Jung Chang, Wen-Sheng Huang, Hsiu-Mei Wu, Wan-Yuo Gu. Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33686089. |
disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from dementia is related to the cellular accumulation of β-amyloid plaques, tau aggregates, or α-synuclein aggregates, or to neurotransmitter deficiencies in the dopaminergic and cholinergic pathways. |
2021-11-22 |
2023-08-13 |
human |
| Tun-Wei Hsu, Jong-Ling Fuh, Da-Wei Wang, Li-Fen Chen, Chia-Jung Chang, Wen-Sheng Huang, Hsiu-Mei Wu, Wan-Yuo Gu. Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33686089. |
however, the role of dopaminergic and cholinergic networks in metabolic connectivity at different stages of dementia remains unclear. |
2021-11-22 |
2023-08-13 |
human |
| Ahsan Bin Tufail, Yong-Kui Ma, Qiu-Na Zhang, Adil Khan, Lei Zhao, Qiang Yang, Muhammad Adeel, Rahim Khan, Inam Ulla. 3D convolutional neural networks-based multiclass classification of Alzheimer's and Parkinson's diseases using PET and SPECT neuroimaging modalities. Brain informatics. vol 8. issue 1. 2021-11-17. PMID:34725741. |
another common subtype of dementia like ad, parkinson's disease (pd) is determined by the disappearance of dopaminergic neurons in the region known as substantia nigra pars compacta located in the midbrain. |
2021-11-17 |
2023-08-13 |
human |
| Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín, José A G Agúnde. Neurochemical Features of Rem Sleep Behaviour Disorder. Journal of personalized medicine. vol 11. issue 9. 2021-10-01. PMID:34575657. |
dopaminergic deficiency, shown by many studies using functional neuroimaging with single photon emission computerized tomography (spect) and positron emission tomography (pet), is the most consistent neurochemical feature of rapid eye movement (rem) sleep behaviour disorder (rbd) and, together with transcranial ultrasonography, and determination of alpha-synuclein in certain tissues, should be considered as a reliable marker for the phenoconversion of idiopathic rbd (irbd) to a synucleopathy (parkinson's disease -pd- or lewy body dementia -lbd). |
2021-10-01 |
2023-08-13 |
Not clear |
| Nico J Diederic. [Causes of visual hallucinations in Parkinson's disease]. Der Nervenarzt. 2021-08-03. PMID:34342675. |
initially dopaminergic overstimulation was discussed as the cause and later on vh have been considered as an early red flag of dementia in pd. |
2021-08-03 |
2023-08-13 |
Not clear |
| Jeffery L Cummings, D P Devanand, Stephen M Stah. Dementia-related psychosis and the potential role for pimavanserin. CNS spectrums. 2021-07-30. PMID:32811586. |
despite differences in dementia pathology, the neurobiology underlying psychosis appears to involve dysregulation of a cortical and limbic pathway involving serotonergic, gamma-aminobutyric acid ergic, glutamatergic, and dopaminergic signaling. |
2021-07-30 |
2023-08-13 |
Not clear |
| Pierpaolo Turcano, Rodolfo Savic. Sex differences in movement disorders. Handbook of clinical neurology. vol 175. 2021-07-28. PMID:33008531. |
movement disorders including parkinson's disease, dementia with lewy body, huntington's disease, tourette's syndrome, and dystonia among others display significant clinical differences between sexes, with structural differences in the dopaminergic pathways between men and women. |
2021-07-28 |
2023-08-13 |
Not clear |
| Yosef Ron, Hedva Lerman, Einat Even-Sapi. [METABOLIC AND DOPAMINERGIC BRAIN FUNCTIONAL IMAGING IN DEMENTIA WITH LEWY BODIES]. Harefuah. vol 160. issue 7. 2021-07-16. PMID:34263568. |
[metabolic and dopaminergic brain functional imaging in dementia with lewy bodies]. |
2021-07-16 |
2023-08-13 |
Not clear |
| Niels Hansen, Claudia Lange, Charles Timäus, Jens Wiltfang, Caroline Boute. Assessing Nigrostriatal Dopaminergic Pathways Frontiers in aging neuroscience. vol 13. 2021-07-09. PMID:34234666. |
assessing nigrostriatal dopaminergic pathways (123)-i-2-ß-carbomethoxy-3ß-(4-iodophenyl)-n-(3-fluoropropyl) nortro- pane single photon emission computed tomography (123i-fp-cit spect) was validated to distinguish alzheimer's dementia from dementia with lewy bodies (dlb) by european medical agencies. |
2021-07-09 |
2023-08-13 |
Not clear |
| P Martinez-Martin, Y M Wan, K Ray Chaudhuri, A E Schrag, D Weintrau. Impulse control and related behaviors in Parkinson's disease with dementia. European journal of neurology. vol 27. issue 6. 2021-06-22. PMID:32048392. |
the objective was to determine the frequency, demographic and clinical correlates [such as age, sex, parkinson's disease (pd) severity and dopaminergic treatment] of impulse control disorder (icd) symptoms and related behaviors in patients with pd with (pd-d) and without (pd-nd) dementia. |
2021-06-22 |
2023-08-13 |
Not clear |
| Jennifer Y Y Szeto, Courtney C Walton, Alexandra Rizos, Pablo Martinez-Martin, Glenda M Halliday, Sharon L Naismith, K Ray Chaudhuri, Simon J G Lewi. Dementia in long-term Parkinson's disease patients: a multicentre retrospective study. NPJ Parkinson's disease. vol 6. 2021-06-05. PMID:31934610. |
no significant differences in age, age onset, disease duration, dopaminergic medication use, and sex distribution were observed between pd patients with and without dementia. |
2021-06-05 |
2023-08-13 |
human |
| Anna Pierzchlińska, Magdalena Kwaśniak-Butowska, Jarosław Sławek, Marek Droździk, Monika Białeck. Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson's Disease. Molecules (Basel, Switzerland). vol 26. issue 6. 2021-05-10. PMID:33802165. |
we aim to review possible vascular and metabolic factors: renin-angiotensin-aldosterone system, vascular endothelial growth factor (vegf), hyperhomocysteinemia (hhcy), as well as the dopaminergic treatment, in the etiopathogenesis of pd dementia. |
2021-05-10 |
2023-08-13 |
Not clear |
| Maria Huber, Leonie Beyer, Catharina Prix, Sonja Schönecker, Carla Palleis, Boris-Stephan Rauchmann, Silvia Morbelli, Andrea Chincarini, Rose Bruffaerts, Rik Vandenberghe, Koen Van Laere, Milica G Kramberger, Maja Trost, Marko Grmek, Valentina Garibotto, Nicolas Nicastro, Giovanni B Frisoni, Afina W Lemstra, Jessica van der Zande, Andrea Pilotto, Alessandro Padovani, Sara Garcia-Ptacek, Irina Savitcheva, Miguel A Ochoa-Figueroa, Anette Davidsson, Valle Camacho, Enrico Peira, Dario Arnaldi, Matteo Bauckneht, Matteo Pardini, Gianmario Sambuceti, Jonathan Vöglein, Jonas Schnabel, Marcus Unterrainer, Robert Perneczky, Oliver Pogarell, Katharina Buerger, Cihan Catak, Peter Bartenstein, Paul Cumming, Michael Ewers, Adrian Danek, Johannes Levin, Dag Aarsland, Flavio Nobili, Axel Rominger, Matthias Brende. Metabolic Correlates of Dopaminergic Loss in Dementia with Lewy Bodies. Movement disorders : official journal of the Movement Disorder Society. vol 35. issue 4. 2021-04-27. PMID:31840326. |
metabolic correlates of dopaminergic loss in dementia with lewy bodies. |
2021-04-27 |
2023-08-13 |
Not clear |
| Sephira G Ryman, Kathleen L Posto. MRI biomarkers of motor and non-motor symptoms in Parkinson's disease. Parkinsonism & related disorders. vol 73. 2021-03-29. PMID:31629653. |
while the early, executive dysfunction observed is consistent with nigrostriatal degeneration, the memory and visuospatial impairments, the harbingers of a dementia process reflect dopaminergic independent dysfunction involving broader regions of the brain. |
2021-03-29 |
2023-08-13 |
Not clear |
| Ho-Man Yeung, Sarah Schmitz, Nino Kvantaliani, Christina Marti. Development of Neuroleptic Malignant Syndrome in a Patient with Lewy Body Dementia after Intramuscular Administration of Paliperidone. Case reports in neurological medicine. vol 2021. 2021-02-02. PMID:33520321. |
due to the extensive neurodegenerative destruction of dopaminergic and acetylcholinergic pathways, patients with lewy body dementia (lbd) are particularly sensitive to antidopaminergic and anticholinergic medications, making them more susceptible to extrapyramidal side effects and nms. |
2021-02-02 |
2023-08-13 |
Not clear |
| Gemma Roberts, Paul C Donaghy, Jim Lloyd, Rory Durcan, George Petrides, Sean J Colloby, Sarah Lawley, Joanna Ciafone, Calum A Hamilton, Michael Firbank, Louise Allan, Nicola Barnett, Sally Barker, Kirsty Olsen, Kim Howe, Tamir Ali, John-Paul Taylor, John O'Brien, Alan J Thoma. Accuracy of dopaminergic imaging as a biomarker for mild cognitive impairment with Lewy bodies. The British journal of psychiatry : the journal of mental science. 2020-12-23. PMID:33355065. |
dopaminergic imaging is an established biomarker for dementia with lewy bodies, but its diagnostic accuracy at the mild cognitive impairment (mci) stage remains uncertain. |
2020-12-23 |
2023-08-13 |
Not clear |
| Alexandre Iarkov, George E Barreto, J Alex Grizzell, Valentina Echeverri. Strategies for the Treatment of Parkinson's Disease: Beyond Dopamine. Frontiers in aging neuroscience. vol 12. 2020-09-28. PMID:32076403. |
parkinson's disease (pd) is the second-leading cause of dementia and is characterized by a progressive loss of dopaminergic neurons in the substantia nigra alongside the presence of intraneuronal α-synuclein-positive inclusions. |
2020-09-28 |
2023-08-13 |
Not clear |
| Andrea Pilotto, Francesca Schiano di Cola, Enrico Premi, Roberto Grasso, Rosanna Turrone, Stefano Gipponi, Andrea Scalvini, Elisabetta Cottini, Barbara Paghera, Valentina Garibotto, Maria Cristina Rizzetti, Laura Bonanni, Barbara Borroni, Silvia Morbelli, Flavio Nobili, Ugo Paolo Guerra, Daniela Perani, Alessandro Padovan. Extrastriatal dopaminergic and serotonergic pathways in Parkinson's disease and in dementia with Lewy bodies: a European journal of nuclear medicine and molecular imaging. vol 46. issue 8. 2020-07-08. PMID:31098748. |
extrastriatal dopaminergic and serotonergic pathways in parkinson's disease and in dementia with lewy bodies: a the aim of the study was to evaluate extrastriatal dopaminergic and serotonergic pathways in patients with parkinson's disease (pd) and dementia with lewy bodies (dlb) using |
2020-07-08 |
2023-08-13 |
Not clear |
| Yu Wei Lin, Daniel Truon. Diffuse Lewy body disease. Journal of the neurological sciences. vol 399. 2020-06-18. PMID:30807982. |
clinical features distinguishing dlb from pdd include the timing of dementia and visual hallucinations, responses to dopaminergic agents and anti-psychotics, and imaging findings. |
2020-06-18 |
2023-08-13 |
Not clear |