| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Ulrich, M Haugh, B H Anderton, A Probst, C Lautenschlager, B Hi. Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes. Acta neuropathologica. vol 73. issue 3. 1987-08-28. PMID:2441559. |
sections of formaldehyde-fixed paraffin-embedded cortical and hippocampal brain tissue from five cases with senile dementia of alzheimer type (sdat) and five cases with pick's disease (pd) were immunostained with the monoclonal antibodies (mabs) 147, rt 97, bf 10 and 8d8 with and without pretreatment with alkaline phosphatase (ap) or trypsin (tr). |
1987-08-28 |
2023-08-11 |
Not clear |
| F Fazekas, J B Chawluk, A Alavi, H I Hurtig, R A Zimmerma. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR. American journal of roentgenology. vol 149. issue 2. 1987-08-17. PMID:3496763. |
areas of high signal intensity affecting hippocampal and sylvian cortex were also present in five alzheimer and two multiinfarct dementia patients, but absent in controls. |
1987-08-17 |
2023-08-11 |
human |
| A Nordberg, P Nyberg, R Adolfsson, B Winbla. Cholinergic topography in Alzheimer brains: a comparison with changes in the monoaminergic profile. Journal of neural transmission. vol 69. issue 1-2. 1987-07-16. PMID:3585318. |
the topographical distribution of the choline acetyltransferase (chat) activity and the number of muscarinic binding sites was studied in the anterio-posterior direction of the caudate nucleus, hippocampus, globus pallidus and putamen of four subjects with senile dementia of alzheimer type (ad/sdat) and in the same regions in six controls. |
1987-07-16 |
2023-08-11 |
human |
| R D Terry, L A Hansen, R DeTeresa, P Davies, H Tobias, R Katzma. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. Journal of neuropathology and experimental neurology. vol 46. issue 3. 1987-05-19. PMID:2881985. |
senile dementia of the alzheimer type (sdat) is typified pathologically by neuritic plaques (np) and neurofibrillary tangles (nft) in the neocortex and hippocampus. |
1987-05-19 |
2023-08-11 |
Not clear |
| H Yamaguchi, M Morimatsu, S Hirai, K Takahash. Alzheimer's neurofibrillary tangles are penetrated by astroglial processes and appear eosinophilic in their final stages. Acta neuropathologica. vol 72. issue 3. 1987-05-18. PMID:2436433. |
alzheimer's neurofibrillary tangles (ant) in the hippocampal area were studied immunohistochemically using antisera against glial fibrillary acidic protein (gfap) and s-100 protein in 48 patients with or without dementia between 52 and 92 years old. |
1987-05-18 |
2023-08-11 |
Not clear |
| W F Maragos, D C Chu, A B Young, C J D'Amato, J B Penne. Loss of hippocampal [3H]TCP binding in Alzheimer's disease. Neuroscience letters. vol 74. issue 3. 1987-05-08. PMID:3031556. |
we have previously demonstrated a marked loss in n-methyl-d-aspartate (nmda) receptors in the hippocampus and cerebral cortex of patients dying with dementia of the alzheimer type (dat). |
1987-05-08 |
2023-08-11 |
Not clear |
| B Szelies, A Karenber. [Disorders of glucose metabolism in Pick's disease]. Fortschritte der Neurologie-Psychiatrie. vol 54. issue 12. 1987-03-30. PMID:3493192. |
pick's disease can be differentiated against presenile dementia represented by alzheimer's disease in that the pattern of reduced metabolism characteristic of alzheimer's disease is different from that of pick's disease where in accordance with the clinical syndrome the glucose metabolism in the frontal and temporobasal regions in reduced, involving also the structures of the hippocampus and an equally significant reduction of glucose metabolism in the caudate nucleus. |
1987-03-30 |
2023-08-11 |
Not clear |
| J T Greenamyre, J B Penney, C J D'Amato, A B Youn. Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. Journal of neurochemistry. vol 48. issue 2. 1987-02-19. PMID:2878980. |
dementia of the alzheimer's type: changes in hippocampal l-[3h]glutamate binding. |
1987-02-19 |
2023-08-11 |
Not clear |
| G Pepeu, F Casamenti, F Pedata, C Cosi, I M Pepe. Are the neurochemical and behavioral changes induced by lesions of the nucleus basalis in the rat a model of Alzheimer's disease? Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:2879319. |
the decrease in choline acetyltransferase (chat) activity in the cortex following unilateral or bilateral electrolytic or neurotoxic lesions of the nucleus basalis are described and compared with the decrease in chat activity found in the cortex and hippocampus of patients affected by senile dementia. |
1987-02-06 |
2023-08-11 |
rat |
| E K Perry, R H Perry, C J Smith, D Purohit, J Bonham, D J Dick, J M Candy, J A Edwardson, A Fairbair. Cholinergic receptors in cognitive disorders. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 13. issue 4 Suppl. 1987-02-06. PMID:3791066. |
cholinergic receptors (muscarinic subtypes m1 and m2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (alzheimer's, parkinson's, and huntington's diseases, down's syndrome and alcoholic dementia) and compared with neurologically normal controls and cases of motor neuron disease. |
1987-02-06 |
2023-08-11 |
Not clear |
| A Nordberg, I Alafuzoff, B Winbla. Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type. Neuroscience letters. vol 70. issue 1. 1986-12-17. PMID:3774212. |
muscarinic receptor subtypes in hippocampus in alzheimer's disease and mixed dementia type. |
1986-12-17 |
2023-08-11 |
Not clear |
| A Nordberg, I Alafuzoff, B Winbla. Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type. Neuroscience letters. vol 70. issue 1. 1986-12-17. PMID:3774212. |
the relative proportion of super-high, high and low affinity agonist binding sites was measured in the hippocampus from individuals with dementia of the alzheimer type (ad/sdat), mixed (ad-mid) type and controls, using labelled quinuclidinyl benzilate ([3h]qnb) competing with unlabelled carbachol. |
1986-12-17 |
2023-08-11 |
Not clear |
| H C Chui, J A Mortimer, U Slager, C Zarow, W Bondareff, D D Webste. Pathologic correlates of dementia in Parkinson's disease. Archives of neurology. vol 43. issue 10. 1986-10-23. PMID:3753274. |
clinicopathologic correlations suggest that dementia with marked visuospatial disturbance as well as severe aphasia may be associated with severe neuronal loss in subcortical nuclei, without significant numbers of plaques or tangles in the hippocampus and cerebral cortex. |
1986-10-23 |
2023-08-11 |
Not clear |
| V Chan-Palay, W Lang, U Haesler, C Köhler, G Yasargi. Distribution of altered hippocampal neurons and axons immunoreactive with antisera against neuropeptide Y in Alzheimer's-type dementia. The Journal of comparative neurology. vol 248. issue 3. 1986-08-20. PMID:3522663. |
distribution of altered hippocampal neurons and axons immunoreactive with antisera against neuropeptide y in alzheimer's-type dementia. |
1986-08-20 |
2023-08-11 |
Not clear |
| V Chan-Palay, W Lang, U Haesler, C Köhler, G Yasargi. Distribution of altered hippocampal neurons and axons immunoreactive with antisera against neuropeptide Y in Alzheimer's-type dementia. The Journal of comparative neurology. vol 248. issue 3. 1986-08-20. PMID:3522663. |
this paper provides detailed information on the distribution of neuropeptide tyrosine (neuropeptide y; npy) immunoreactive neurons and fibers in the hippocampal region of eight neuropathologically confirmed cases of alzheimer's-type dementia (atd) at postmortem. |
1986-08-20 |
2023-08-11 |
Not clear |
| A M Palmer, A W Procter, G C Stratmann, D M Bowe. Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease. Neuroscience letters. vol 66. issue 2. 1986-08-12. PMID:3014387. |
brains of normal controls and patients with primary degenerative dementia were investigated for choline acetyltransferase (chat) activity in the frontal, temporal and parietal cortex, hippocampus, amygdala and thalamus. |
1986-08-12 |
2023-08-11 |
Not clear |
| F Koukolí. [Criticism of the hippocampal hypothesis of dementia in Alzheimer's disease]. Casopis lekaru ceskych. vol 124. issue 48. 1986-01-22. PMID:4064101. |
[criticism of the hippocampal hypothesis of dementia in alzheimer's disease]. |
1986-01-22 |
2023-08-11 |
Not clear |
| B T Volpe, C K Petit. Dementia with bilateral medial temporal lobe ischemia. Neurology. vol 35. issue 12. 1986-01-03. PMID:4069376. |
neuropathologic examination of two patients with dementia showed chronic bilateral medial temporal lobe ischemic damage that included the hippocampus (particularly the ca-1 region), subiculum, and amygdala. |
1986-01-03 |
2023-08-11 |
Not clear |
| D M Mann, P O Yates, B Marcyniu. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. Journal of the neurological sciences. vol 69. issue 3. 1985-10-07. PMID:3162000. |
some morphometric observations on the cerebral cortex and hippocampus in presenile alzheimer's disease, senile dementia of alzheimer type and down's syndrome in middle age. |
1985-10-07 |
2023-08-11 |
Not clear |
| J O Rinne, K Laakso, P Lönnberg, P Mölsä, L Paljärvi, J K Rinne, E Säkö, U K Rinn. Brain muscarinic receptors in senile dementia. Brain research. vol 336. issue 1. 1985-08-20. PMID:4005573. |
the binding of [3h]qnb was significantly decreased in the hippocampus, amygdala and nucleus accumbens in patients with alzheimer's disease (ad) and with combined type of dementia (cd), whereas in patients with multi-infarct dementia (mid) the binding was not significantly decreased in the limbic areas but only in the caudate nucleus. |
1985-08-20 |
2023-08-11 |
Not clear |