| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nadia M Tsankova, Olivier Berton, William Renthal, Arvind Kumar, Rachel L Neve, Eric J Nestle. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nature neuroscience. vol 9. issue 4. 2006-06-08. PMID:16501568. |
to better understand the molecular mechanisms of depression and antidepressant action, we administered chronic social defeat stress followed by chronic imipramine (a tricyclic antidepressant) to mice and studied adaptations at the levels of gene expression and chromatin remodeling of five brain-derived neurotrophic factor (bdnf) splice variant mrnas (i-v) and their unique promoters in the hippocampus. |
2006-06-08 |
2023-08-12 |
mouse |
| Gigliola Grassi Zucconi, Sabrina Cipriani, Ioanna Balgkouranidou, Roberto Scatton. 'One night' sleep deprivation stimulates hippocampal neurogenesis. Brain research bulletin. vol 69. issue 4. 2006-06-08. PMID:16624668. |
among these, dysregulation of hippocampal neurogenesis has been recently implicated in the pathogenesis of depression. |
2006-06-08 |
2023-08-12 |
rat |
| Alexandre Serrano, Nasser Haddjeri, Jean-Claude Lacaille, Richard Robitaill. GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 20. 2006-06-08. PMID:16707789. |
gabaergic network activation of glial cells underlies hippocampal heterosynaptic depression. |
2006-06-08 |
2023-08-12 |
Not clear |
| Alexandre Serrano, Nasser Haddjeri, Jean-Claude Lacaille, Richard Robitaill. GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 20. 2006-06-08. PMID:16707789. |
tetanus-induced heterosynaptic depression in the hippocampus is a key cellular mechanism in neural networks implicated in learning and memory. |
2006-06-08 |
2023-08-12 |
Not clear |
| Robert Pawlak, B S Shankaranarayana Rao, Jerry P Melchor, Sumantra Chattarji, Bruce McEwen, Sidney Stricklan. Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 50. 2006-05-30. PMID:16330749. |
although behavioral evidence suggests that severe stress triggers cognitive impairment, as seen in major depression or posttraumatic stress disorder, little is known about the molecular mediators of these functional deficits in the hippocampus. |
2006-05-30 |
2023-08-12 |
mouse |
| Juan Beauquis, Paulina Roig, Françoise Homo-Delarche, Alejandro De Nicola, Flavia Saravi. Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin-induced diabetic mice: reversion by antidepressant treatment. The European journal of neuroscience. vol 23. issue 6. 2006-05-30. PMID:16553617. |
an association between depression and defective hippocampal neurogenesis has been proposed and, in rodents, antidepressant therapy restores neuronal proliferation in the dentate gyrus. |
2006-05-30 |
2023-08-12 |
mouse |
| Eric Vermetten, Christian Schmahl, Sanneke Lindner, Richard J Loewenstein, J Douglas Bremne. Hippocampal and amygdalar volumes in dissociative identity disorder. The American journal of psychiatry. vol 163. issue 4. 2006-05-24. PMID:16585437. |
smaller hippocampal volume has been reported in several stress-related psychiatric disorders, including posttraumatic stress disorder (ptsd), borderline personality disorder with early abuse, and depression with early abuse. |
2006-05-24 |
2023-08-12 |
Not clear |
| Jun Xia, Jun Chen, Yicheng Zhou, Jingfeng Zhang, Bo Yang, Liming Xia, Chengyuan Wan. Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 5. 2006-05-12. PMID:15641704. |
volumetric mri analysis of the amygdala and hippocampus in subjects with major depression. |
2006-05-12 |
2023-08-12 |
human |
| Jun Xia, Jun Chen, Yicheng Zhou, Jingfeng Zhang, Bo Yang, Liming Xia, Chengyuan Wan. Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 5. 2006-05-12. PMID:15641704. |
in order to explore the mri volume of the amygdala and hippocampus in patients with major depression, quantitative mri of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. |
2006-05-12 |
2023-08-12 |
human |
| Jun Xia, Jun Chen, Yicheng Zhou, Jingfeng Zhang, Bo Yang, Liming Xia, Chengyuan Wan. Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 5. 2006-05-12. PMID:15641704. |
the volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. |
2006-05-12 |
2023-08-12 |
human |
| Jun Xia, Jun Chen, Yicheng Zhou, Jingfeng Zhang, Bo Yang, Liming Xia, Chengyuan Wan. Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 5. 2006-05-12. PMID:15641704. |
it was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression. |
2006-05-12 |
2023-08-12 |
human |
| Jennifer L Warner-Schmidt, Ronald S Duma. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus. vol 16. issue 3. 2006-05-04. PMID:16425236. |
preclinical and clinical studies demonstrate that stress and depression lead to reductions of the total volume of this structure and atrophy and loss of neurons in the adult hippocampus. |
2006-05-04 |
2023-08-12 |
Not clear |
| Li-Ming Zhang, Yun-Feng Li, Ze-Hui Gon. [Neurogenesis: a novel strategy for the treatment of depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 36. issue 2. 2006-05-03. PMID:16222968. |
the waning and waxing of neurogenesis in hippocampus is proposed as a key factor in the decent into and recovery from depression. |
2006-05-03 |
2023-08-12 |
Not clear |
| Li-Ming Zhang, Yun-Feng Li, Ze-Hui Gon. [Neurogenesis: a novel strategy for the treatment of depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 36. issue 2. 2006-05-03. PMID:16222968. |
if hippocampal neurogenesis was blocked, antidepressant would lose its behavioral effects in behavioral models of depression. |
2006-05-03 |
2023-08-12 |
Not clear |
| Jolanta Orzeł-Gryglewska, Edyta Jurkowlaniec, Weronika Trojnia. Microinjection of procaine and electrolytic lesion in the ventral tegmental area suppresses hippocampal theta rhythm in urethane-anesthetized rats. Brain research bulletin. vol 68. issue 5. 2006-04-20. PMID:16377435. |
depression of the power of the 3-6 hz component of the eeg signal was also seen in spontaneous hippocampal eeg after procaine. |
2006-04-20 |
2023-08-12 |
rat |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? |
2006-04-17 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
the hippocampus plays a critical role in both seizure activity and mood disorders, which suggests that pathology in this area of the brain might provide a link between epilepsy and depression. |
2006-04-17 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
recent findings support the view that neurogenesis is not the only factor that contributes to the pathomechanism of depression and antidepressant responses, which may involve other hippocampal cellular or molecular changes, or both. |
2006-04-17 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
specifically, remodeling of the hippocampal spine synapses may play a significant role in the neurobiology of depression and the effects of antidepressant therapy. |
2006-04-17 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
paradoxical features of epilepsy, i.e., seizure-induced increases in hippocampal neurotrophin expression and neurogenesis, suggest that the most important factor in the neurobiology of depression might be the extent to which the hippocampus can adapt appropriately to changes in the environment through alterations in hippocampal synaptic connectivity. |
2006-04-17 |
2023-08-12 |
Not clear |