| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paulianda J Jones, Ellen C Merrick, Timothy W Batts, Nicholas J Hargus, Yuesheng Wang, James P Stables, Edward H Bertram, Milton L Brown, Manoj K Pate. Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy. The Journal of pharmacology and experimental therapeutics. vol 328. issue 1. 2009-02-03. PMID:18952887. |
in membrane excitability experiments, ywi92 inhibited burst firing in ca1 neurons of animals with temporal lobe epilepsy at concentrations that had little effect on ca1 neurons from control animals. |
2009-02-03 |
2023-08-12 |
human |
| Flavia Antonucci, Angelo Di Garbo, Elena Novelli, Ilaria Manno, Ferdinando Sartucci, Yuri Bozzi, Matteo Cale. Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18177862. |
botulinum neurotoxin e (bont/e) reduces ca1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy. |
2008-06-20 |
2023-08-12 |
mouse |
| Christian Frisch, Alexei P Kudin, Christian E Elger, Wolfram S Kunz, Christoph Helmstaedte. Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent. Epilepsy research. vol 73. issue 2. 2007-05-08. PMID:17084066. |
we have shown recently that topiramate (tpm) dose-dependently protects hippocampal ca1 and ca3 neurons during initial status epilepticus in the rat pilocarpine model of temporal lobe epilepsy by inhibition of mitochondrial transition pore opening. |
2007-05-08 |
2023-08-12 |
rat |
| Nathalie Sanon, Lionel Carmant, Martine Emond, Patrice Congar, Jean-Claude Lacaill. Short-term effects of kainic acid on CA1 hippocampal interneurons differentially vulnerable to excitotoxicity. Epilepsia. vol 46. issue 6. 2005-06-30. PMID:15946325. |
we sought to identify the inhibitory interneurons of the rat hippocampal ca1 region selectively vulnerable in the kainic acid (ka) model of temporal lobe epilepsy and to determine whether their selective vulnerability could be due to differential short-term ka effects. |
2005-06-30 |
2023-08-12 |
rat |
| A Bordey, D D Spence. Distinct electrophysiological alterations in dentate gyrus versus CA1 glial cells from epileptic humans with temporal lobe sclerosis. Epilepsy research. vol 59. issue 2-3. 2004-10-12. PMID:15246115. |
previous studies have characterized the electrophysiological properties of astrocytes in the ca1 region of hippocampi resected from patients with intractable temporal lobe epilepsy (tle). |
2004-10-12 |
2023-08-12 |
human |
| F R Tang, S C Chia, P M Chen, H Gao, W L Lee, T S Yeo, J M Burgunder, A Probst, M K Sim, E A Lin. Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus. Epilepsy research. vol 59. issue 2-3. 2004-10-12. PMID:15246118. |
in the mouse model at 2 months apise, mglur2/3 immunopositive product in two-thirds of the slm near the stratum radiatum disappeared, and so did in the whole slm of ca1 area in patients with mesial temporal lobe epilepsy. |
2004-10-12 |
2023-08-12 |
mouse |
| Seong Yun Kim, Do Sik Min, Jeong-Sun Choi, Yun Sik Choi, Hyun-Jung Park, Ki-Wug Sung, Joonmo Kim, Mun-Yong Le. Differential expression of phospholipase D isozymes in the hippocampus following kainic acid-induced seizures. Journal of neuropathology and experimental neurology. vol 63. issue 8. 2004-09-14. PMID:15330336. |
pld1 immunoreactivity increased preferentially in the ca3 and ca1 regions, where pyramidal neurons are susceptible to temporal lobe epilepsy. |
2004-09-14 |
2023-08-12 |
human |
| L Stan Leung, ChiPing W. Kindling suppresses primed-burst-induced long-term potentiation in hippocampal CA1. Neuroreport. vol 14. issue 2. 2003-04-30. PMID:12598731. |
in a previous study, we showed that partial hippocampal kindling in rats, a model of temporal lobe epilepsy, reduced the efficacy of presynaptic gaba(b) receptors in the ca1 area of hippocampal slices. |
2003-04-30 |
2023-08-12 |
rat |
| K Wu, L S Leun. Increased dendritic excitability in hippocampal ca1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis. Neuroscience. vol 116. issue 2. 2003-04-17. PMID:12559115. |
increased dendritic excitability in hippocampal ca1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis. |
2003-04-17 |
2023-08-12 |
rat |
| K Wu, L S Leun. Increased dendritic excitability in hippocampal ca1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis. Neuroscience. vol 116. issue 2. 2003-04-17. PMID:12559115. |
we used kainic acid in rats as an animal model of temporal lobe epilepsy, and studied the synaptic transmission in hippocampal subfield ca1 of urethane-anesthetized rats in vivo. |
2003-04-17 |
2023-08-12 |
rat |
| L Wittner, L Eross, Z Szabó, Sz Tóth, S Czirják, P Halász, T F Freund, Z S Maglóczk. Synaptic reorganization of calbindin-positive neurons in the human hippocampal CA1 region in temporal lobe epilepsy. Neuroscience. vol 115. issue 3. 2003-04-07. PMID:12435433. |
synaptic reorganization of calbindin-positive neurons in the human hippocampal ca1 region in temporal lobe epilepsy. |
2003-04-07 |
2023-08-12 |
human |
| Ashok K Shett. Entorhinal axons exhibit sprouting in CA1 subfield of the adult hippocampus in a rat model of temporal lobe epilepsy. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201638. |
entorhinal axons exhibit sprouting in ca1 subfield of the adult hippocampus in a rat model of temporal lobe epilepsy. |
2003-03-05 |
2023-08-12 |
rat |
| Tomohiro Araki, Roger P Simon, Waro Taki, Jing-Quan Lan, David C Henshal. Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. Journal of neuroscience research. vol 69. issue 5. 2002-11-15. PMID:12210827. |
damage was largely restricted to the ipsilateral ca3 subfield of the hippocampus, but injury was also consistent within ca1, suggesting that this mouse model better reflects the hippocampal neuropathology of human temporal lobe epilepsy than does the rat, in which ca1 is typically spared. |
2002-11-15 |
2023-08-12 |
mouse |
| Maria Thom, Sanjay M Sisodiya, Andrew Beckett, Lillian Martinian, Woan-Ru Lin, William Harkness, Tejal N Mitchell, John Craig, John Duncan, Francesco Scaravill. Cytoarchitectural abnormalities in hippocampal sclerosis. Journal of neuropathology and experimental neurology. vol 61. issue 6. 2002-07-08. PMID:12071634. |
hippocampal sclerosis (hs) is the most common pathological substrate for temporal lobe epilepsy with a characteristic pattern of loss of principle neurons primarily in ca1 and hilar subfields. |
2002-07-08 |
2023-08-12 |
human |
| F R Tang, W L Lee, T T Ye. Expression of the group I metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy. Journal of neurocytology. vol 30. issue 5. 2002-07-01. PMID:11951051. |
immunocytochemical studies at light and electron microscopic levels in hippocampi of patients with mesial temporal lobe epilepsy showed mglur1 and mglur5 immunoreactivity in the molecular layer of the dentate gyrus and ca1 area, especially at the border between stratum oriens and alveus. |
2002-07-01 |
2023-08-12 |
Not clear |
| M Jeub, H Beck, E Siep, C Rüschenschmidt, E-J Speckmann, U Ebert, H Potschka, C Freichel, E Reissmüller, W Lösche. Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats. Neuropharmacology. vol 42. issue 1. 2002-02-20. PMID:11750920. |
in line with this proposal, a reduced effect of carbamazepine on sodium currents in hippocampal ca1 neurons was found in the rat kindling model of temporal lobe epilepsy (tle), i.e. |
2002-02-20 |
2023-08-12 |
rat |
| M J Denslow, T Eid, F Du, R Schwarcz, E W Lothman, O Stewar. Disruption of inhibition in area CA1 of the hippocampus in a rat model of temporal lobe epilepsy. Journal of neurophysiology. vol 86. issue 5. 2002-02-06. PMID:11698514. |
disruption of inhibition in area ca1 of the hippocampus in a rat model of temporal lobe epilepsy. |
2002-02-06 |
2023-08-12 |
rat |
| A K Shetty, D A Turne. Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102487. |
degeneration of ca3-pyramidal neurons in hippocampus after intracerebroventricular kainic acid (ka) administration, a model of temporal lobe epilepsy, results in hyperexcitability within both dentate gyrus and the ca1 subfield. |
2001-02-08 |
2023-08-12 |
rat |
| T N Lehmann, S Gabriel, R Kovacs, A Eilers, A Kivi, K Schulze, W R Lanksch, H J Meencke, U Heineman. Alterations of neuronal connectivity in area CA1 of hippocampal slices from temporal lobe epilepsy patients and from pilocarpine-treated epileptic rats. Epilepsia. vol 41 Suppl 6. 2000-10-17. PMID:10999543. |
alterations of neuronal connectivity in area ca1 of hippocampal slices from temporal lobe epilepsy patients and from pilocarpine-treated epileptic rats. |
2000-10-17 |
2023-08-12 |
human |
| T N Lehmann, S Gabriel, R Kovacs, A Eilers, A Kivi, K Schulze, W R Lanksch, H J Meencke, U Heineman. Alterations of neuronal connectivity in area CA1 of hippocampal slices from temporal lobe epilepsy patients and from pilocarpine-treated epileptic rats. Epilepsia. vol 41 Suppl 6. 2000-10-17. PMID:10999543. |
therefore, we studied sprouting in area ca1 because this region is most affected in human temporal lobe epilepsy. |
2000-10-17 |
2023-08-12 |
human |