| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robbert G E Notenboom, David R Hampson, Gerard H Jansen, Peter C van Rijen, Cees W M van Veelen, Onno van Nieuwenhuizen, Pierre N E de Graa. Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients. Brain : a journal of neurology. vol 129. issue Pt 1. 2006-01-25. PMID:16311265. |
up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients. |
2006-01-25 |
2023-08-12 |
human |
| Robbert G E Notenboom, David R Hampson, Gerard H Jansen, Peter C van Rijen, Cees W M van Veelen, Onno van Nieuwenhuizen, Pierre N E de Graa. Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients. Brain : a journal of neurology. vol 129. issue Pt 1. 2006-01-25. PMID:16311265. |
in this study, we examined the distribution of mglur1alpha and mglur5 immunoreactivity (ir) in hippocampal resection tissue from pharmaco-resistant temporal lobe epilepsy (tle) patients. |
2006-01-25 |
2023-08-12 |
human |
| Robert Brenner, Qing H Chen, Alex Vilaythong, Glenn M Toney, Jeffrey L Noebels, Richard W Aldric. BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nature neuroscience. vol 8. issue 12. 2006-01-24. PMID:16261134. |
consistent with breakdown of the dentate filter, beta4 knockouts show distinctive seizures emanating from the temporal cortex, demonstrating a unique nonsynaptic mechanism for gate control of hippocampal synchronization leading to temporal lobe epilepsy. |
2006-01-24 |
2023-08-12 |
mouse |
| Silke Penschuck, Jesper F Bastlund, Henrik Sindal Jensen, Tine Bryan Stensbol, Jan Egebjerg, William P Watso. Changes in KCNQ2 immunoreactivity in the amygdala in two rat models of temporal lobe epilepsy. Brain research. Molecular brain research. vol 141. issue 1. 2006-01-23. PMID:16154661. |
this study describes the expression of kcnq2 subunit immunoreactivity in the basolateral amygdala in two rat models of temporal lobe epilepsy, (1) amygdala kindling and (2) spontaneously epileptic rats after status epilepticus induced by hippocampal electrical stimulation. |
2006-01-23 |
2023-08-12 |
rat |
| Lionel Thivard, Stéphane Lehéricy, Alexandre Krainik, Claude Adam, Didier Dormont, Jacques Chiras, Michel Baulac, Sophie Dupon. Diffusion tensor imaging in medial temporal lobe epilepsy with hippocampal sclerosis. NeuroImage. vol 28. issue 3. 2006-01-17. PMID:16084113. |
diffusion tensor imaging in medial temporal lobe epilepsy with hippocampal sclerosis. |
2006-01-17 |
2023-08-12 |
human |
| Lionel Thivard, Stéphane Lehéricy, Alexandre Krainik, Claude Adam, Didier Dormont, Jacques Chiras, Michel Baulac, Sophie Dupon. Diffusion tensor imaging in medial temporal lobe epilepsy with hippocampal sclerosis. NeuroImage. vol 28. issue 3. 2006-01-17. PMID:16084113. |
interictal diffusion imaging studies in patients with medial temporal lobe epilepsy (mtle) accompanied by hippocampal sclerosis (hs) have shown an increased diffusivity in the epileptogenic hippocampus. |
2006-01-17 |
2023-08-12 |
human |
| Jae-Won Yang, Thomas Czech, Ellen Gelpi, Gert Lube. Extravasation of plasma proteins can confound interpretation of proteomic studies of brain: a lesson from apo A-I in mesial temporal lobe epilepsy. Brain research. Molecular brain research. vol 139. issue 2. 2006-01-17. PMID:16095751. |
we searched for aberrant protein expression in hippocampus from patients with mesial temporal lobe epilepsy (mtle) by an analytical method based on two-dimensional gel electrophoresis coupled with mass spectrometry (maldi-tof/tof) and unambiguously identified 2 spots as apolipoprotein a-i forms in brain of mtle patients with 7.5-fold increased levels (controls: 0.046 +/- 0.046; mtle patients: 0.343 +/- 0.154, mean +/- sd, p = 0.003). |
2006-01-17 |
2023-08-12 |
Not clear |
| Bouchaïb El Bahh, Silvia Balosso, Trevor Hamilton, Herbert Herzog, Annette G Beck-Sickinger, Günther Sperk, Donald R Gehlert, Annamaria Vezzani, William F Colmer. The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors. The European journal of neuroscience. vol 22. issue 6. 2006-01-10. PMID:16190896. |
in hippocampal slices from rats and several wild-type mice, a y2-preferring agonist mimicked, and the y2-specific antagonist biie0246 blocked, the npy-mediated inhibition both of glutamatergic transmission and of epileptiform discharges in two different slice models of temporal lobe epilepsy, stimulus train-induced bursting (stib) and 0-mg2+ bursting. |
2006-01-10 |
2023-08-12 |
mouse |
| Neda Bernasconi, Jun Natsume, Andrea Bernascon. Progression in temporal lobe epilepsy: differential atrophy in mesial temporal structures. Neurology. vol 65. issue 2. 2006-01-04. PMID:16043790. |
to determine the relationship between hippocampal, amygdalar, and entorhinal cortex atrophy and duration of epilepsy, presence of secondary generalized seizures, and prolonged childhood febrile convulsions in patients with pharmacologically intractable temporal lobe epilepsy (tle). |
2006-01-04 |
2023-08-12 |
Not clear |
| Shaoyun Chen, Paul S Buckmaste. Stereological analysis of forebrain regions in kainate-treated epileptic rats. Brain research. vol 1057. issue 1-2. 2006-01-04. PMID:16122711. |
in this status epilepticus-based model, extrahippocampal damage appears to be more extensive and hippocampal damage appears to be less extensive than that reported for patients with temporal lobe epilepsy. |
2006-01-04 |
2023-08-12 |
rat |
| Oliver Kann, Richard Kovács, Marleisje Njunting, Christoph Joseph Behrens, Jakub Otáhal, Thomas-Nicolas Lehmann, Siegrun Gabriel, Uwe Heineman. Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans. Brain : a journal of neurology. vol 128. issue Pt 10. 2005-12-29. PMID:15958506. |
metabolic dysfunction has been implicated in the pathogenesis of temporal lobe epilepsy (tle), but its manifestation during neuronal activation in the ex vivo hippocampus from tle patients has not been shown. |
2005-12-29 |
2023-08-12 |
rat |
| S J Mulani, S V Kothare, D P Patka. Magnetic resonance volumetric analysis of hippocampi in children in the age group of 6-to-12 years: a pilot study. Neuroradiology. vol 47. issue 7. 2005-12-22. PMID:15915343. |
atrophy of the mesial temporal structures, especially the hippocampus, has been implicated in temporal lobe epilepsy. |
2005-12-22 |
2023-08-12 |
Not clear |
| Reinhard Schulz, Simone Horstmann, Hennric Jokeit, Friedrich G Woermann, Alois Ebne. Epilepsy surgery in professional musicians: subjective and objective reports of three cases. Epilepsy & behavior : E&B. vol 7. issue 3. 2005-12-20. PMID:16143569. |
we describe a small series of three professional musicians who had right (two patients) and left (one patient) temporal lobe epilepsy surgery with the histological diagnoses of hippocampal sclerosis (two patients) and benign tumor (one patient, xanthoastrocytoma). |
2005-12-20 |
2023-08-12 |
Not clear |
| Suzanne B Bausc. Axonal sprouting of GABAergic interneurons in temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 7. issue 3. 2005-12-20. PMID:16198153. |
one feature found in both humans and animal models is sprouting of hippocampal principal cell axons, which suggests that axonal sprouting may be a general phenomenon associated with temporal lobe epilepsy. |
2005-12-20 |
2023-08-12 |
Not clear |
| Suzanne B Bausc. Axonal sprouting of GABAergic interneurons in temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 7. issue 3. 2005-12-20. PMID:16198153. |
this article highlights the evidence showing that hippocampal gabaergic interneurons also undergo axonal sprouting in temporal lobe epilepsy. |
2005-12-20 |
2023-08-12 |
Not clear |
| Zsolt Csaba, Susanne Pirker, Benjamin Lelouvier, Axelle Simon, Catherine Videau, Jacques Epelbaum, Thomas Czech, Christoph Baumgartner, Günther Sperk, Pascal Dournau. Somatostatin receptor type 2 undergoes plastic changes in the human epileptic dentate gyrus. Journal of neuropathology and experimental neurology. vol 64. issue 11. 2005-12-15. PMID:16254490. |
temporal lobe epilepsy (tle) is characterized by hippocampal sclerosis together with profound losses and phenotypic changes of different classes of interneurons, including those expressing somatostatin (srif). |
2005-12-15 |
2023-08-12 |
human |
| Marc Steffens, Hans-Jürgen Huppertz, Josef Zentner, Emmanuelle Chauzit, Thomas J Feuerstei. Unchanged glutamine synthetase activity and increased NMDA receptor density in epileptic human neocortex: implications for the pathophysiology of epilepsy. Neurochemistry international. vol 47. issue 6. 2005-12-13. PMID:16095760. |
loss of glutamine synthetase in the human epileptic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy. |
2005-12-13 |
2023-08-12 |
human |
| Nihal C de Lanerolle, Tih-Shih Le. New facets of the neuropathology and molecular profile of human temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 7. issue 2. 2005-12-07. PMID:16098816. |
this review summarizes the salient features of the anatomical and molecular neuropathology of the hippocampus from patients with intractable temporal lobe epilepsy (tle). |
2005-12-07 |
2023-08-12 |
human |
| Michael Seidenberg, Elizabeth Geary, Bruce Herman. Investigating temporal lobe contribution to confrontation naming using MRI quantitative volumetrics. Journal of the International Neuropsychological Society : JINS. vol 11. issue 4. 2005-12-07. PMID:16209415. |
in the current paper, we used quantitative mr volumetrics to investigate the relative contribution of the hippocampus and extrahippocampal temporal lobe (segmented gray and white matter) volumes to confrontation naming performance in 53 patients with temporal lobe epilepsy. |
2005-12-07 |
2023-08-12 |
Not clear |
| D L Buhl, G Buzsák. Developmental emergence of hippocampal fast-field "ripple" oscillations in the behaving rat pups. Neuroscience. vol 134. issue 4. 2005-11-15. PMID:16039793. |
spike sequences associated with sharp waves are believed to play a critical role in transferring transient memories from the hippocampus to the neocortex and the emergence of superfast ripples is pathognostic in temporal lobe epilepsy. |
2005-11-15 |
2023-08-12 |
rat |