| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiping Liang, Qin Hu, Bo Li, Devin McBride, Hetao Bian, Pierre Spagnoli, Di Chen, Jiping Tang, John H Zhan. Follistatin-like 1 attenuates apoptosis via disco-interacting protein 2 homolog A/Akt pathway after middle cerebral artery occlusion in rats. Stroke. vol 45. issue 10. 2015-01-26. PMID:25139876. |
follistatin-like 1 (fstl1), an extracellular glycoprotein, has been reported to decrease apoptosis in ischemic cardiac diseases, but its effect in ischemic stroke has not been examined. |
2015-01-26 |
2023-08-13 |
rat |
| Adam Hafeez, Omar Elmadhoun, Changya Peng, Jamie Y Ding, Xiaokun Geng, Murali Guthikonda, Yuchuan Din. Reduced Apoptosis by Ethanol and Its Association with PKC-δ and Akt Signaling in Ischemic Stroke. Aging and disease. vol 5. issue 6. 2014-12-09. PMID:25489491. |
reduced apoptosis by ethanol and its association with pkc-δ and akt signaling in ischemic stroke. |
2014-12-09 |
2023-08-13 |
rat |
| Lin Wang, Feng Jiang, Qifeng Li, Xiaoguang He, Jie M. Mild hypothermia combined with neural stem cell transplantation for hypoxic-ischemic encephalopathy: neuroprotective effects of combined therapy. Neural regeneration research. vol 9. issue 19. 2014-11-25. PMID:25422635. |
neural stem cell transplantation is a useful treatment for ischemic stroke, but apoptosis often occurs in the hypoxic-ischemic environment of the brain after cell transplantation. |
2014-11-25 |
2023-08-13 |
mouse |
| Dong-Mei Liu, Zhen-Hui Wang, Li Liu, Xiu-Mei Zhang, Feng-Lan Lo. Acetylpuerarin increases cell viability and reduces apoptosis in rat hippocampal neurons following oxygen‑glucose deprivation/reperfusion. Molecular medicine reports. vol 8. issue 5. 2014-11-13. PMID:24026460. |
in conclusion, acetylpuerarin protects against ogd/r-induced neuronal apoptosis predominantly in the first 24 h following ischemia, which may be useful in mediating neuronal apoptosis in ischemic stroke patients. |
2014-11-13 |
2023-08-12 |
rat |
| Lu Liu, Ying Gao, Bin M. Exploring molecular mechanism underlying Chinese medicine syndrome: a study on correlation between Chinese medicine syndrome and biomarkers for ischemic stroke. Chinese journal of integrative medicine. vol 20. issue 1. 2014-10-07. PMID:23529833. |
to investigate whether chinese medicine (cm) syndrome is associated with particular molecular mechanism, we explored the correlation between cm syndrome and changes of intercellular adhesion molecule-1 (icam-1), matrix metalloproteinase 9 (mmp-9) and heat shock protein 70 (hsp70) in patients with ischemic stroke, which were reported to play an important role in the inflammatory and apoptosis cascade. |
2014-10-07 |
2023-08-12 |
Not clear |
| Songsheng Shi, Weizhong Yang, Xiankun Tu, Chunmei Chen, Chunhua Wan. Ischemic preconditioning reduces ischemic brain injury by suppressing nuclear factor kappa B expression and neuronal apoptosis. Neural regeneration research. vol 8. issue 7. 2014-09-10. PMID:25206708. |
ischemic stroke induces a series of complex pathophysiological events including blood-brain barrier disruption, inflammatory response and neuronal apoptosis. |
2014-09-10 |
2023-08-13 |
rat |
| Nam Pham, Arti Dhar, Siavash Khalaj, Kash Desai, Changiz Taghibiglo. Down regulation of brain cellular prion protein in an animal model of insulin resistance: possible implication in increased prevalence of stroke in pre-diabetics/diabetics. Biochemical and biophysical research communications. vol 448. issue 2. 2014-08-26. PMID:24780399. |
considering a neuroprotective role for prp(c) and the involvement of nr2b subunit in the excitotoxicity-induced neuronal apoptosis, these phenomena may contribute to the severity and poor prognosis of ischemic stroke in diabetes/prediabetes. |
2014-08-26 |
2023-08-13 |
rat |
| Ozge Cevik, Zelal Adiguzel, Ahmet Tarik Baykal, Goksel Somay, Azize Sene. The apoptotic actions of platelets in acute ischemic stroke. Molecular biology reports. vol 40. issue 12. 2014-07-02. PMID:24057255. |
we herein examined the relationship between the potential cytokine, tnf-α platelet activation and apoptosis in acute ischemic stroke patients. |
2014-07-02 |
2023-08-12 |
human |
| Ozge Cevik, Zelal Adiguzel, Ahmet Tarik Baykal, Goksel Somay, Azize Sene. The apoptotic actions of platelets in acute ischemic stroke. Molecular biology reports. vol 40. issue 12. 2014-07-02. PMID:24057255. |
the data of this work suggests that inflammation may have a role in platelet apoptosis in stroke which may suggest a new aspect of the role of inflammation in the development of acute ischemic stroke. |
2014-07-02 |
2023-08-12 |
human |
| Yang Sun, Huan Gui, Qi Li, Zhu-Min Luo, Min-Jun Zheng, Jun-Li Duan, Xia Li. MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke. CNS neuroscience & therapeutics. vol 19. issue 10. 2014-05-08. PMID:23826665. |
microrna-124 protects neurons against apoptosis in cerebral ischemic stroke. |
2014-05-08 |
2023-08-12 |
Not clear |
| Anca Stefania Slujitoru, Andreea Lorena Enache, Irina Lavinia Pintea, Elisabeta Rolea, Cristina Mariana Stocheci, O T Pop, Anca Predesc. Clinical and morphological correlations in acute ischemic stroke. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 53. issue 4. 2014-05-05. PMID:23303014. |
the following clinical and morphological correlations were established: liquefactive necrosis, astrocyte gliosis, phagocytosis phenomena are the more intense the later the death of the patient; apoptosis phenomena are the more intense the faster the death of the patient; the entire cerebral microcirculation presented microscopic modifications following the ischemic strokes, regardless of the time since the lesion occurred and the histological examination was made; the major neurological complications of the ischemic stroke - the hemorrhagic transformation phenomena, cerebral edema, were microscopically objectified, regardless of the time since the lesion occurred and the histological examination was made. |
2014-05-05 |
2023-08-12 |
Not clear |
| Xiaokun Geng, Sweena Parmar, Xuemei Li, Changya Peng, Xunming Ji, Tia Chakraborty, William A Li, Huishan Du, Xiaomu Tan, Feng Ling, Murali Guthikonda, José A Rafols, Yuchuan Din. Reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke. Brain research. vol 1531. 2014-04-10. PMID:23920008. |
reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke. |
2014-04-10 |
2023-08-12 |
rat |
| Bin Deng, Xingchun Gou, Hai Chen, Liya Li, Haixing Zhong, Hao Xu, Fengliang Jiang, Zhijing Zhao, Qiang Wang, Lixian X. Targeted delivery of neurogenin-2 protein in the treatment for cerebral ischemia-reperfusion injury. Biomaterials. vol 34. issue 34. 2014-03-26. PMID:23942209. |
in conclusion, the targeted delivery of tat-lbd-ngn2 into the ischemic zone attenuated cerebral ischemia-reperfusion injury through the inhibition of neuronal degeneration and apoptosis, suggesting that tat-lbd-ngn2 is a promising target candidate for the treatment of ischemic stroke. |
2014-03-26 |
2023-08-12 |
mouse |
| Dujuan Sha, Zhongyuan Wang, Lai Qian, Yong Han, Jun Zhang, Shuangshuang Gu, Luna Wang, Jie Li, Cong Chen, Yun X. A cocaine-regulated and amphetamine-regulated transcript inhibits oxidative stress in neurons deprived of oxygen and glucose. Neuroreport. vol 24. issue 13. 2014-02-24. PMID:23884173. |
oxidative stress is an important trigger of neuronal apoptosis in ischemic stroke. |
2014-02-24 |
2023-08-12 |
Not clear |
| Paul Fu, Changya Peng, Jamie Y Ding, Karam Asmaro, Jonathon M Sullivan, Murali Guthikonda, Yuchuan Din. Acute administration of ethanol reduces apoptosis following ischemic stroke in rats. Neuroscience research. vol 76. issue 1-2. 2014-01-17. PMID:23511554. |
acute administration of ethanol reduces apoptosis following ischemic stroke in rats. |
2014-01-17 |
2023-08-12 |
rat |
| Nsikan Akpan, Carol M Tro. Caspase inhibitors: prospective therapies for stroke. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 19. issue 2. 2013-08-30. PMID:22645109. |
in ischemic stroke, apoptosis persists for days to weeks after the onset of an ischemic event. |
2013-08-30 |
2023-08-12 |
Not clear |
| Alexander Widiapradja, Viktor Vegh, Ker Zhing Lok, Silvia Manzanero, John Thundyil, Mathias Gelderblom, Yi-Lin Cheng, Dale Pavlovski, Sung-Chun Tang, Dong-Gyu Jo, Tim Magnus, Sic L Chan, Christopher G Sobey, David Reutens, Milan Basta, Mark P Mattson, Thiruma V Arumuga. Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22494053. |
treatment of mice with ivig reduced neuronal cell loss, apoptosis and infarct size, and improved functional outcome in a model of focal ischemic stroke. |
2013-08-14 |
2023-08-12 |
mouse |
| Alexander Widiapradja, Viktor Vegh, Ker Zhing Lok, Silvia Manzanero, John Thundyil, Mathias Gelderblom, Yi-Lin Cheng, Dale Pavlovski, Sung-Chun Tang, Dong-Gyu Jo, Tim Magnus, Sic L Chan, Christopher G Sobey, David Reutens, Milan Basta, Mark P Mattson, Thiruma V Arumuga. Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22494053. |
together, these results indicate that ivig acts directly on neurons to protect them against ischemic stroke and aβ-induced neuronal apoptosis by inhibiting cell death pathways and by elevating levels of the anti-apoptotic protein bcl2. |
2013-08-14 |
2023-08-12 |
mouse |
| Shaojing Li, Chuanhong Wu, Li Zhu, Jian Gao, Jing Fang, Defeng Li, Meihong Fu, Rixin Liang, Lan Wang, Ming Cheng, Hongjun Yan. By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke. Molecules (Basel, Switzerland). vol 17. issue 11. 2013-04-05. PMID:23143152. |
by improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke. |
2013-04-05 |
2023-08-12 |
rat |
| Chi Kyung Kim, Taeho Kim, In-Young Choi, Min Soh, Dohoung Kim, Young-Ju Kim, Hyunduk Jang, Hye-Sung Yang, Jun Yup Kim, Hong-Kyun Park, Seung Pyo Park, Sangseung Park, Taekyung Yu, Byung-Woo Yoon, Seung-Hoon Lee, Taeghwan Hyeo. Ceria nanoparticles that can protect against ischemic stroke. Angewandte Chemie (International ed. in English). vol 51. issue 44. 2013-01-22. PMID:22968916. |
uniform 3 nm-sized ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species (ros) and reducing apoptosis. |
2013-01-22 |
2023-08-12 |
Not clear |