| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ye-Cheng Liu, Zhi-Wei Qi, Sui Ma, Xiao-Yu Cui, Hou-Li Wang, Shu-Bin Guo, Zhong Wang, Xue-Zhong Y. [Apoptosis of gastric mucosa and gastric barrier dysfunction in acute ischemic stroke]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 30. issue 2. 2010-05-28. PMID:18505114. |
to evaluate the role of gastric mucosa apoptosis in the stress of ischemic stroke, and to discuss the relationship between gastric mucosa apoptosis and gastric barrier. |
2010-05-28 |
2023-08-12 |
Not clear |
| Toru Yamashita, Kentaro Deguchi, Shoko Nagotani, Tatsushi Kamiya, Koji Ab. Gene and stem cell therapy in ischemic stroke. Cell transplantation. vol 18. issue 9. 2010-03-26. PMID:19523331. |
possible strategies for treating ischemic stroke include neuroprotection (preventing injured neurons from undergoing apoptosis in the acute phase of cerebral ischemia) and stem cell therapy (the repair of disrupted neuronal networks with newly born neurons in the chronic phase of cerebral ischemia). |
2010-03-26 |
2023-08-12 |
Not clear |
| K K Wan. Caspases: a drug discovery perspective. Current opinion in drug discovery & development. vol 2. issue 5. 2009-12-11. PMID:19649979. |
recent advances in the elucidation of the biochemical machinery of apoptosis have allowed us to appreciate the significance of unscheduled apoptosis in a wide range of human diseases and disorders, such as ischemic stroke, traumatic brain injury, alzheimer's disease, drug-induced liver injury and cardiac ischemia. |
2009-12-11 |
2023-08-12 |
human |
| Toru Yamashita, Kentaro Deguchi, Yoshihide Sehara, Violeta Lukic-Panin, Hanzhe Zhang, Tatsushi Kamiya, Koji Ab. Therapeutic strategy for ischemic stroke. Neurochemical research. vol 34. issue 4. 2009-06-03. PMID:18770029. |
possible strategies for treating ischemic stroke include: (1) neuroprotection: preventing damaged neurons from undergoing apoptosis in the acute phase of cerebral ischemia; (2) stem cell therapy: the repair of broken neuronal networks with newly born neurons in the chronic phase of cerebral ischemia. |
2009-06-03 |
2023-08-12 |
rat |
| Hai-Yan Hong, Jung Sook Choi, Yoon Jung Kim, Hwa Young Lee, Wonjung Kwak, Jeongsoo Yoo, Jae-Tae Lee, Tae-Hwan Kwon, In-San Kim, Hyung-Soo Han, Byung-Heon Le. Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display. Journal of controlled release : official journal of the Controlled Release Society. vol 131. issue 3. 2009-01-21. PMID:18692101. |
we attempted to identify peptides that can home to ischemic stroke tissue and detect the apoptosis of cells. |
2009-01-21 |
2023-08-12 |
rat |
| Nicholas Mitsios, John Gaffney, Jerzy Krupinski, Richard Mathias, Qiuyu Wang, Stuart Hayward, Francisco Rubio, Patricia Kumar, Shant Kumar, Mark Slevi. Expression of signaling molecules associated with apoptosis in human ischemic stroke tissue. Cell biochemistry and biophysics. vol 47. issue 1. 2008-01-03. PMID:17406061. |
expression of signaling molecules associated with apoptosis in human ischemic stroke tissue. |
2008-01-03 |
2023-08-12 |
human |
| Gineta Liutkiene, Rimvydas Stropus, Anita Dabuzinskiene, Mara Pilman. Structural changes of the human superior cervical ganglion following ischemic stroke. Medicina (Kaunas, Lithuania). vol 43. issue 5. 2007-07-09. PMID:17563416. |
the aim of this study was to investigate signs of the neurodegenerative alteration in the sympathetic ganglia including the evaluation of apoptosis of neuronal and satellite cells in the human superior cervical ganglion after ischemic stroke, because so far alterations in human sympathetic ganglia related to the injury to peripheral tissue have not been enough analyzed. |
2007-07-09 |
2023-08-12 |
human |
| Celine A Beamer, Diane M Brooks, Diana I Luri. Motheaten (me/me) mice deficient in SHP-1 are less susceptible to focal cerebral ischemia. Journal of neuroscience research. vol 83. issue 7. 2006-07-25. PMID:16528752. |
taken together, these results demonstrate that loss of shp-1 results in greater healing of the infarct due to less apoptosis and more neuronal survival in the ischemic core and suggests that pharmacologic inactivation of shp-1 may have potential therapeutic value in limiting cns degeneration after ischemic stroke. |
2006-07-25 |
2023-08-12 |
mouse |
| Ling Wei, Byung H Han, Ying Li, Christine L Keogh, David M Holtzman, Shan Ping Y. Cell death mechanism and protective effect of erythropoietin after focal ischemia in the whisker-barrel cortex of neonatal rats. The Journal of pharmacology and experimental therapeutics. vol 317. issue 1. 2006-05-25. PMID:16357210. |
based on the notion that 1) ischemic stroke is a relatively common disorder in human neonates, and 2) developing cells are more susceptible to apoptosis, the present study examined whether typical apoptosis was induced by cerebral ischemia in a new neonatal rat model. |
2006-05-25 |
2023-08-12 |
human |
| Chun-Fang Xia, Robert S Smith, Bo Shen, Zhi-Rong Yang, Cesar V Borlongan, Lee Chao, Julie Cha. Postischemic brain injury is exacerbated in mice lacking the kinin B2 receptor. Hypertension (Dallas, Tex. : 1979). vol 47. issue 4. 2006-04-20. PMID:16534002. |
these results indicate that the kinin b2 receptor promotes survival and protects against brain injury by suppression of apoptosis and inflammation induced by ischemic stroke. |
2006-04-20 |
2023-08-12 |
mouse |
| Chun-Fang Xia, Hang Yin, Cesar V Borlongan, Julie Chao, Lee Cha. Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis. Experimental neurology. vol 197. issue 2. 2006-04-03. PMID:16343485. |
postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis. |
2006-04-03 |
2023-08-12 |
Not clear |
| Chun-Fang Xia, Hang Yin, Yu-Yu Yao, Cesar V Borlongan, Lee Chao, Julie Cha. Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. Human gene therapy. vol 17. issue 2. 2006-03-10. PMID:16454654. |
kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. |
2006-03-10 |
2023-08-12 |
human |
| V A Aĭvazian, A S Boiadzhian, L A Manukian, G V Avetisian, G S Grigoria. [Complement componenets, C3 and factors B, in the blood of patients with acute ischemic stroke]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol Suppl 15. 2006-02-16. PMID:16447555. |
several studies suggest that activation of compliment cascade contributes to the development of the inflammatory immune response in ischemic stroke and results in tissue injury by initiating apoptosis and necrosis. |
2006-02-16 |
2023-08-12 |
Not clear |
| Taizen Nakase, Shinji Fushiki, Goran Söhl, Martin Theis, Klaus Willecke, Christian C G Nau. Neuroprotective role of astrocytic gap junctions in ischemic stroke. Cell communication & adhesion. vol 10. issue 4-6. 2004-11-15. PMID:14681050. |
astrocytic gap junctions may reduce apoptosis and inflammation in the penumbra following ischemic insult, suggesting that coupled astrocytes fulfill a neuroprotective role under ischemic stroke conditions. |
2004-11-15 |
2023-08-12 |
mouse |
| Oleksandr Ekshyyan, Tak Yee A. Apoptosis in acute and chronic neurological disorders. Frontiers in bioscience : a journal and virtual library. vol 9. 2004-06-02. PMID:14977568. |
however, premature apoptosis and/or aberrations in apoptosis control contribute to the pathogenesis of a variety of neurological disorders including acute brain injury such as trauma, spinal cord injury, ischemic stroke and ischemia/reperfusion as well as chronic disease states such as alzheimer's, parkinson's, huntington's, amyotrophic lateral sclerosis, spinal muscular atrophy, and diabetic neuropathy. |
2004-06-02 |
2023-08-12 |
Not clear |
| Chun-Fang Xia, Hang Yin, Cesar V Borlongan, Lee Chao, Julie Cha. Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis. Hypertension (Dallas, Tex. : 1979). vol 43. issue 2. 2004-04-12. PMID:14698996. |
kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis. |
2004-04-12 |
2023-08-12 |
human |
| Filomena de Nigris, Amir Lerman, Louis J Ignarro, Sharon Williams-Ignarro, Vincenzo Sica, Andrew H Baker, Lilach O Lerman, Yong J Geng, Claudio Napol. Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis. Trends in molecular medicine. vol 9. issue 8. 2004-03-31. PMID:12928037. |
however, overall, oxidation and apoptosis appear to promote the progression of diseased arteries towards a lesion that is vulnerable to rupture, and to give rise to myocardial infarction and ischemic stroke. |
2004-03-31 |
2023-08-12 |
Not clear |
| I Irminger-Finger, W C Leung, J Li, M Dubois-Dauphin, J Harb, A Feki, C E Jefford, J V Soriano, M Jaconi, R Montesano, K H Kraus. Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis. Molecular cell. vol 8. issue 6. 2002-01-16. PMID:11779501. |
we suggest that bard1 is a mediator of apoptosis since (1) cell death in vivo (ischemic stroke) and in vitro is accompanied by increased levels of bard1 protein and mrna; (2) overexpression of bard1 induces cell death with all features of apoptosis; and (3) bard1-repressed cells are defective for the apoptotic response to genotoxic stress. |
2002-01-16 |
2023-08-12 |
Not clear |
| J Zaremb. Contribution of tumor necrosis factor alpha to the pathogenesis of stroke. Folia morphologica. vol 59. issue 3. 2000-09-26. PMID:10974781. |
being the final morphological effect of ischemic stroke, tnf-alpha appears also to contribute to neuronal necrosis by its involvement in the process of apoptosis as well as in the death of neurons. |
2000-09-26 |
2023-08-12 |
Not clear |
| S I Savitz, J A Erhardt, J V Anthony, G Gupta, X Li, F C Barone, D M Rosenbau. The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 8. 2000-08-30. PMID:10950380. |
increasing evidence supports a role for oxidative stress, proinflammatory cytokines, and apoptosis in the pathophysiology of focal ischemic stroke. |
2000-08-30 |
2023-08-12 |
rat |