| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qingwen Hu, Tianrui Zuo, Ling Deng, Sha Chen, Wu Yu, Shengwei Liu, JingDong Liu, Xuan Wang, Xiaomei Fan, Zhi Don. β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 102. 2022-05-13. PMID:35550220. |
ischemic stroke is a complex brain disease regulated by several cell death processes, including apoptosis, autophagy, and ferroptosis. |
2022-05-13 |
2023-08-13 |
rat |
| Yuting Nie, Lulu Wen, Hui Li, Juexian Song, Ningqun Wang, Liyuan Huang, Li Gao, Miao Q. Tanhuo Formula Inhibits Astrocyte Activation and Apoptosis in Acute Ischemic Stroke. Frontiers in pharmacology. vol 13. 2022-05-13. PMID:35559267. |
tanhuo formula inhibits astrocyte activation and apoptosis in acute ischemic stroke. |
2022-05-13 |
2023-08-13 |
Not clear |
| Zhi-Jia Liu, Cun-Ping Wang, Bin Yang, Nan Wang, Qin Wang, Jian Gu, Rui Ta. [Protective effect and mechanism of Ershiwuwei Zhenzhu Pills on cerebral apoplexy rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 8. 2022-05-09. PMID:35531722. |
ershiwuwei zhenzhu pills has a protective effect on ischemic stroke rats, and its mechanism may be related to anti-inflammation, anti-oxidation, promotion of nerve cell proliferation, inhibition nerve cell apoptosis and promotion of angiogenesis. |
2022-05-09 |
2023-08-13 |
rat |
| Gang Wang, Ying Zhou, Tingting Zhong, Aixia Song, Qian Xu. Longitudinal variation of circulating Inc-ITSN1-2: A novel biomarker reflecting disease severity, inflammation, recurrence, and death risk in acute ischemic stroke patients. Journal of clinical laboratory analysis. 2022-05-02. PMID:35500161. |
long noncoding rna intersectin 1-2 (lnc-itsn1-2) regulates inflammation and neuronal apoptosis; meanwhile, the latter two factors participate in the pathogenesis of acute ischemic stroke (ais). |
2022-05-02 |
2023-08-13 |
Not clear |
| Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wan. Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviated ischemic stroke reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways. Pharmacological research. 2022-04-28. PMID:35483515. |
ischemic stroke reperfusion (ir) can cause adverse reactions including apoptosis, oxidative stress, and inflammation, but the existing therapeutic strategies have been limited. |
2022-04-28 |
2023-08-13 |
rat |
| Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wan. Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviated ischemic stroke reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways. Pharmacological research. 2022-04-28. PMID:35483515. |
our findings revealed for the first that sc against ir injury by reducing inflammation and apoptosis while simultaneously acting as potential therapeutic lead compound for ischemic stroke. |
2022-04-28 |
2023-08-13 |
rat |
| Chen Xie, Bin Zhu, Juxian Gu, Muhua Su. The correlation of lncRNA SNHG16 with inflammatory cytokines, adhesion molecules, disease severity, and prognosis in acute ischemic stroke patients. Journal of clinical laboratory analysis. 2022-04-20. PMID:35441431. |
long non-coding rna small nucleolar rna host gene 16 (lncrna snhg16) is involved in the pathogenesis of acute ischemic stroke (ais) through the regulation of brain endothelial cell viability, inflammation, atherosclerotic plaque formation, and neural apoptosis. |
2022-04-20 |
2023-08-13 |
Not clear |
| Lele Feng, Ruofei Tian, Xingdou Mu, Cheng Chen, Yuxi Zhang, Jun Cui, Yujie Song, Yingying Liu, Miao Zhang, Lei Shi, Yang Sun, Ling Li, Wei Y. Identification of Genes Linking Natural Killer Cells to Apoptosis in Acute Myocardial Infarction and Ischemic Stroke. Frontiers in immunology. vol 13. 2022-04-18. PMID:35432334. |
identification of genes linking natural killer cells to apoptosis in acute myocardial infarction and ischemic stroke. |
2022-04-18 |
2023-08-13 |
Not clear |
| Lele Feng, Ruofei Tian, Xingdou Mu, Cheng Chen, Yuxi Zhang, Jun Cui, Yujie Song, Yingying Liu, Miao Zhang, Lei Shi, Yang Sun, Ling Li, Wei Y. Identification of Genes Linking Natural Killer Cells to Apoptosis in Acute Myocardial Infarction and Ischemic Stroke. Frontiers in immunology. vol 13. 2022-04-18. PMID:35432334. |
in this study, we explored the distinct patterns of nk cell infiltration and apoptosis during the pathological progression of acute myocardial infarction and ischemic stroke using mrna expression microarrays from the gene expression omnibus database. |
2022-04-18 |
2023-08-13 |
Not clear |
| Lele Feng, Ruofei Tian, Xingdou Mu, Cheng Chen, Yuxi Zhang, Jun Cui, Yujie Song, Yingying Liu, Miao Zhang, Lei Shi, Yang Sun, Ling Li, Wei Y. Identification of Genes Linking Natural Killer Cells to Apoptosis in Acute Myocardial Infarction and Ischemic Stroke. Frontiers in immunology. vol 13. 2022-04-18. PMID:35432334. |
together, these findings suggest that these apoptosis-related genes may play important roles in the mechanisms underlying the patterns of nk cell abundance and apoptosis in acute myocardial infarction and ischemic stroke. |
2022-04-18 |
2023-08-13 |
Not clear |
| Ramón Iglesias-Rey, Antía Custodia, Maria Luz Alonso-Alonso, Iria López-Dequidt, Manuel Rodríguez-Yáñez, José M Pumar, José Castillo, Tomás Sobrino, Francisco Campos, Andres da Silva-Candal, Pablo Hervell. The Smoking Paradox in Stroke Patients Under Reperfusion Treatment Is Associated With Endothelial Dysfunction. Frontiers in neurology. vol 13. 2022-04-11. PMID:35401421. |
this study aimed to explore the association between smoking habit and the serum levels of soluble tumor necrosis factor-like weak inducer of apoptosis (stweak), in relation with the functional outcome of patients with acute ischemic stroke undergoing reperfusion treatment. |
2022-04-11 |
2023-08-13 |
Not clear |
| Jingjing Zhao, Qianwen Wang, Ruixia Zhu, Jun Yan. Circulating Non-coding RNAs as Potential Biomarkers for Ischemic Stroke: A Systematic Review. Journal of molecular neuroscience : MN. 2022-04-05. PMID:35380333. |
recent studies have demonstrated that dysregulated non-coding rnas (ncrnas) are involved in the pathogenesis of ischemic stroke (is), including neuroinflammation, apoptosis, atherosclerosis, and angiogenesis. |
2022-04-05 |
2023-08-13 |
Not clear |
| Bin Chen, Xiao-Yong Zhong, Xiao-Fang You, Wan-Qing Li. [Electroacupuncture promotes the repair of neurological function in ischemic stroke rats by inhi-biting cofilin rod formation]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 3. 2022-03-23. PMID:35319840. |
to observe the effect of electroacupuncture (ea) on modified neurological severity score (mnss), cerebral infarction volume, expression of lim domain kinase-1 (limk1) and slingshot homolog-1 (ssh1) proteins, cofilin rod formation and neural cell apoptosis in rats with ischemic stroke (is), so as to explore its mechanisms underlying improvement of is. |
2022-03-23 |
2023-08-13 |
rat |
| Tingting Zhu, Hongxi Chen, Cuihong He, Xiaojuan Li. Transcription Factor HEY1 Improves Brain Vascular Endothelial Cell Function and Alleviates Ischemic Stroke by Upregulating NOTCH3. Neurochemical research. 2022-03-22. PMID:35316462. |
hey1 suppresses apoptosis and inflammation and promotes proliferation and migration in bmvecs by upregulating notch3, thereby ameliorating ischemic stroke. |
2022-03-22 |
2023-08-13 |
rat |
| Yamei Li, Bo Peng, Yi Li, Airu Huang, Yinian Peng, Qian Yu, Yufeng L. MiR-203a-3p/153-3p improves cognitive impairments induced by ischemia/reperfusion via blockade of SRC-mediated MAPK signaling pathway in ischemic stroke. Chemico-biological interactions. 2022-03-20. PMID:35305977. |
thus, mir-203a-3p and mir-153-3p confers neuroprotective effects against ischemic stroke via attenuation of apoptosis, oxidative stress and inflammatory pathways through inhibiting src-dependent mapk signaling pathway in vivo and in vitro, suggesting new therapeutic targets for the prevention and treatment of stroke. |
2022-03-20 |
2023-08-13 |
rat |
| Yule Wang, Huimin Wu, Zhu Han, Hongda Sheng, Yuhan Wu, Yingchao Wang, Xinran Guo, Yan Zhu, Xuecai Li, Yi Wan. Guhong injection promotes post-stroke functional recovery via attenuating cortical inflammation and apoptosis in subacute stage of ischemic stroke. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 99. 2022-03-11. PMID:35276592. |
guhong injection promotes post-stroke functional recovery via attenuating cortical inflammation and apoptosis in subacute stage of ischemic stroke. |
2022-03-11 |
2023-08-13 |
Not clear |
| Sen Zhang, De-Wen Kong, Guo-Dong Ma, Cheng-di Liu, Yu-Jiao Yang, Shan Liu, Nan Jiang, Zi-Rong Pan, Wen Zhang, Ling-Lei Kong, Guan-Hua D. Long-term administration of salvianolic acid A promotes endogenous neurogenesis in ischemic stroke rats through activating Wnt3a/GSK3β/β-catenin signaling pathway. Acta pharmacologica Sinica. 2022-02-26. PMID:35217812. |
taken together, our results demonstrate that long-term administration of saa improves neurological function through enhancing endogenous neurogenesis and inhibiting neuronal apoptosis in ischemic stroke rats via activating wnt3a/gsk3β/β-catenin signaling pathway. |
2022-02-26 |
2023-08-13 |
rat |
| Chunliu Tang, Jiefeng Luo, Xianjia Yan, Qiaojuan Huang, Zhenhua Huang, Qi Luo, Yuan Lan, Dingzhi Chen, Baolin Zhang, Menghua Chen, Deyan Kon. Melanin nanoparticles enhance the neuroprotection of mesenchymal stem cells against hypoxic-ischemic injury by inhibiting apoptosis and upregulating antioxidant defense. Cell biology international. 2022-02-16. PMID:35170135. |
these findings suggest that mnps enhance the neuroprotective effect of mscs against hypoxic-ischemic injury by inhibiting apoptosis and upregulating antioxidant defense, which could provide some evidence for the potential application of combined mnps and mscs in the therapy for ischemic stroke. |
2022-02-16 |
2023-08-13 |
Not clear |
| Balu Joshi, Devendra Singh, Himika Wasan, Uma Sharma, K H Reet. Tideglusib Ameliorates Ischemia/Reperfusion Damage by Inhibiting GSK-3β and Apoptosis in Rat Model of Ischemic Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 4. 2022-02-13. PMID:35152130. |
tideglusib ameliorates ischemia/reperfusion damage by inhibiting gsk-3β and apoptosis in rat model of ischemic stroke. |
2022-02-13 |
2023-08-13 |
rat |
| Jason A Glab, Hamsa Puthalakath, Shenpeng R Zhang, Antony Vinh, Grant R Drummond, Christopher G Sobey, T Michael De Silva, Hyun Ah Ki. Bim Deletion Reduces Functional Deficits Following Ischemic Stroke in Association with Modulation of Apoptosis and Inflammation. Neuromolecular medicine. 2022-02-12. PMID:35149957. |
bim deletion reduces functional deficits following ischemic stroke in association with modulation of apoptosis and inflammation. |
2022-02-12 |
2023-08-13 |
mouse |