| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pollyanna Barros Batista, Stela Maris Aguiar Lemos, Luiz Oswaldo Carneiro Rodrigues, Nilton Alves de Rezend. Auditory temporal processing deficits and language disorders in patients with neurofibromatosis type 1. Journal of communication disorders. vol 48. 2014-12-19. PMID:24447521. |
these results suggest that the neurofibromin deficiency found in nf1 patients is associated with auditory temporal processing deficits, which may contribute to the cognitive impairment, learning disabilities, and attention deficits that are common in this disorder. |
2014-12-19 |
2023-08-12 |
human |
| Brigitte C Widemann, Maria T Acosta, Sylvia Ammoun, Allan J Belzberg, Andre Bernards, Jaishri Blakeley, Antony Bretscher, Karen Cichowski, D Wade Clapp, Eva Dombi, Gareth D Evans, Rosalie Ferner, Cristina Fernandez-Valle, Michael J Fisher, Marco Giovannini, David H Gutmann, C Oliver Hanemann, Robert Hennigan, Susan Huson, David Ingram, Joe Kissil, Bruce R Korf, Eric Legius, Roger J Packer, Andrea I McClatchey, Frank McCormick, Kathryn North, Minja Pehrsson, Scott R Plotkin, Vijaya Ramesh, Nancy Ratner, Susann Schirmer, Larry Sherman, Elizabeth Schorry, David Stevenson, Douglas R Stewart, Nicole Ullrich, Annette C Bakker, Helen Morriso. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American journal of medical genetics. Part A. vol 164A. issue 3. 2014-11-03. PMID:24443315. |
individuals with nf1 may demonstrate manifestations in multiple organ systems, including tumors of the nervous system, learning disabilities, and physical disfigurement. |
2014-11-03 |
2023-08-12 |
Not clear |
| Sofia Granström, Reinhard E Friedrich, Anna Katharina Langenbruch, Matthias Augustin, Victor-Felix Mautne. Influence of learning disabilities on the tumour predisposition syndrome NF1--survey from adult patients' perspective. Anticancer research. vol 34. issue 7. 2014-08-21. PMID:24982386. |
influence of learning disabilities on the tumour predisposition syndrome nf1--survey from adult patients' perspective. |
2014-08-21 |
2023-08-13 |
Not clear |
| Sofia Granström, Reinhard E Friedrich, Anna Katharina Langenbruch, Matthias Augustin, Victor-Felix Mautne. Influence of learning disabilities on the tumour predisposition syndrome NF1--survey from adult patients' perspective. Anticancer research. vol 34. issue 7. 2014-08-21. PMID:24982386. |
to analyze psychosocial burdens associated with neurofibromatosis type-1 (nf1) phenotype--visible symptoms, medical complications, learning disabilities (ld)--from patients' perspective with focus on ld. |
2014-08-21 |
2023-08-13 |
Not clear |
| Miladys Orraca-Castillo, Nancy Estévez-Pérez, Vivian Reigosa-Cresp. Neurocognitive profiles of learning disabled children with neurofibromatosis type 1. Frontiers in human neuroscience. vol 8. 2014-06-17. PMID:24936179. |
neurofibromatosis 1 (nf1) is a genetic condition generally associated with intellectual deficiency and learning disabilities. |
2014-06-17 |
2023-08-13 |
Not clear |
| Florian Mainberger, Nikolai H Jung, Martin Zenker, Ute Wahlländer, Leonie Freudenberg, Susanne Langer, Steffen Berweck, Tobias Winkler, Andreas Straube, Florian Heinen, Sofia Granström, Victor-Felix Mautner, Karen Lidzba, Volker Mal. Lovastatin improves impaired synaptic plasticity and phasic alertness in patients with neurofibromatosis type 1. BMC neurology. vol 13. 2014-04-04. PMID:24088225. |
neurofibromatosis type 1 (nf1) is one of the most common genetic disorders causing learning disabilities by mutations in the neurofibromin gene, an important inhibitor of the ras pathway. |
2014-04-04 |
2023-08-12 |
mouse |
| Ana F Oliveira, Ryohei Yasud. Neurofibromin is the major ras inactivator in dendritic spines. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 3. 2014-03-13. PMID:24431436. |
therefore, deregulation of postsynaptic ras signaling may explain, at least in part, learning disabilities associated with nf1. |
2014-03-13 |
2023-08-12 |
rat |
| Katherine H Karlsgodt, Tena Rosser, Evan S Lutkenhoff, Tyrone D Cannon, Alcino Silva, Carrie E Bearde. Alterations in white matter microstructure in neurofibromatosis-1. PloS one. vol 7. issue 10. 2013-04-01. PMID:23094098. |
neurofibromatosis (nf1) represents the most common single gene cause of learning disabilities. |
2013-04-01 |
2023-08-12 |
human |
| Blair C Armstrong, Janelle C Le Boutillier, Ted L Peti. Ultrastructural synaptic changes associated with neurofibromatosis type 1: a quantitative analysis of hippocampal region CA1 in a Nf1(+/-) mouse model. Synapse (New York, N.Y.). vol 66. issue 3. 2012-11-09. PMID:22121000. |
neurofibromatosis type 1 (nf1) is one of the most frequently diagnosed autosomal dominant inherited disorders resulting in neurological dysfunction, including an assortment of learning disabilities and cognitive deficits. |
2012-11-09 |
2023-08-12 |
mouse |
| Maria T Acosta, Carrie E Bearden, F Xavier Castellanos, Xavier F Castellanos, Laurie Cutting, Ype Elgersma, Gerard Gioia, David H Gutmann, Yong-Seok Lee, Eric Legius, Maximillian Muenke, Kathryn North, Luis F Parada, Nancy Ratner, Kim Hunter-Schaedle, Alcino J Silv. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American journal of medical genetics. Part A. vol 158A. issue 9. 2012-11-09. PMID:22821737. |
the learning disabilities network (leadnet): using neurofibromatosis type 1 (nf1) as a paradigm for translational research. |
2012-11-09 |
2023-08-12 |
Not clear |
| Maria T Acosta, Carrie E Bearden, F Xavier Castellanos, Xavier F Castellanos, Laurie Cutting, Ype Elgersma, Gerard Gioia, David H Gutmann, Yong-Seok Lee, Eric Legius, Maximillian Muenke, Kathryn North, Luis F Parada, Nancy Ratner, Kim Hunter-Schaedle, Alcino J Silv. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American journal of medical genetics. Part A. vol 158A. issue 9. 2012-11-09. PMID:22821737. |
the successes with nf1 have allowed leadnet investigators to broaden their initial focus to other genetic disorders characterized by learning disabilities and cognitive deficits including other rasopathies (caused by changes in the ras signaling pathway). |
2012-11-09 |
2023-08-12 |
Not clear |
| Jacquelyn A Brown, Kelly A Diggs-Andrews, Scott M Gianino, David H Gutman. Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner. Molecular and cellular neurosciences. vol 49. issue 1. 2012-04-05. PMID:21903164. |
children with the neurofibromatosis-1 (nf1) cancer predisposition syndrome exhibit numerous clinical problems that reflect defective central nervous system (cns) neuronal function, including learning disabilities, attention deficit disorder, and seizures. |
2012-04-05 |
2023-08-12 |
mouse |
| Yunus Kasim Terzi, Burcu Sirin, Esra Serdaroglu, Banu Anlar, Sabiha Aysun, Guzen Hosgor, Elif Acar Arslan, Sukriye Ayte. Absence of exon 17 c.2970-2872delAAT mutation in Turkish NF1 patients with mild phenotype. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 27. issue 12. 2012-03-12. PMID:21732117. |
neurofibromatosis type 1 (nf1) is an autosomal dominant disorder characterized by café-au-lait spots, neurofibromas, skinfold freckles, lisch nodules, bone deformities, learning disabilities, and predisposition to neoplasms. |
2012-03-12 |
2023-08-12 |
Not clear |
| Yunus Kasim Terzi, Sibel Oğuzkan-Balci, Banu Anlar, Emel Erdoğan-Bakar, Sükriye Ayte. Learning disability and oligodendrocyte myelin glycoprotein (OMGP) gene in neurofibromatosis type 1. The Turkish journal of pediatrics. vol 53. issue 1. 2011-06-14. PMID:21534343. |
the oligodendrocyte myelin glycoprotein (omgp) gene located within the neurofibromatosis type 1 (nf1) gene might affect the phenotype of learning disability because it is expressed in the brain, and omgp gene mutations have been associated with cognitive disturbances. |
2011-06-14 |
2023-08-12 |
Not clear |
| Yunus Kasim Terzi, Sibel Oğuzkan-Balci, Banu Anlar, Emel Erdoğan-Bakar, Sükriye Ayte. Learning disability and oligodendrocyte myelin glycoprotein (OMGP) gene in neurofibromatosis type 1. The Turkish journal of pediatrics. vol 53. issue 1. 2011-06-14. PMID:21534343. |
we analyzed the omgp gene in nf1 patients with and without learning disability (n = 50 each) and healthy controls (n = 100). |
2011-06-14 |
2023-08-12 |
Not clear |
| Yunus Kasim Terzi, Sibel Oğuzkan-Balci, Banu Anlar, Emel Erdoğan-Bakar, Sükriye Ayte. Learning disability and oligodendrocyte myelin glycoprotein (OMGP) gene in neurofibromatosis type 1. The Turkish journal of pediatrics. vol 53. issue 1. 2011-06-14. PMID:21534343. |
these results do not support a relationship between the omgp gene and the learning disability phenotype observed in nf1. |
2011-06-14 |
2023-08-12 |
Not clear |
| Susan M Huson, Maria T Acosta, Allan J Belzberg, Andre Bernards, Jonathan Chernoff, Karen Cichowski, D Gareth Evans, Rosalie E Ferner, Marco Giovannini, Bruce R Korf, Robert Listernick, Kathryn N North, Roger J Packer, Luis F Parada, Juha Peltonen, Vijaya Ramesh, Karlyne M Reilly, John W Risner, Elizabeth K Schorry, Meena Upadhyaya, David H Viskochil, Yuan Zhu, Kim Hunter-Schaedle, Filippo G Giancott. Back to the future: proceedings from the 2010 NF Conference. American journal of medical genetics. Part A. vol 155A. issue 2. 2011-05-20. PMID:21271647. |
individuals with nf1 in particular may develop tumors anywhere in the nervous system; additional manifestations can include learning disabilities, bone dysplasia, cardiovascular defects, unmanageable pain, and physical disfigurement. |
2011-05-20 |
2023-08-12 |
Not clear |
| Caroline Hachon, Stéphanie Iannuzzi, Yves Chai. Behavioural and cognitive phenotypes in children with neurofibromatosis type 1 (NF1): the link with the neurobiological level. Brain & development. vol 33. issue 1. 2011-04-11. PMID:20106617. |
approximately 50% of children with nf1 develop learning disabilities notably for reading. |
2011-04-11 |
2023-08-12 |
Not clear |
| C Shilyansky, Y S Lee, A J Silv. Molecular and cellular mechanisms of learning disabilities: a focus on NF1. Annual review of neuroscience. vol 33. 2011-01-27. PMID:20345245. |
molecular and cellular mechanisms of learning disabilities: a focus on nf1. |
2011-01-27 |
2023-08-12 |
human |
| C Shilyansky, Y S Lee, A J Silv. Molecular and cellular mechanisms of learning disabilities: a focus on NF1. Annual review of neuroscience. vol 33. 2011-01-27. PMID:20345245. |
neurofibromatosis type i (nf1) is a single-gene disorder characterized by a high incidence of complex cognitive symptoms, including learning disabilities, attention deficit disorder, executive function deficits, and motor coordination problems. |
2011-01-27 |
2023-08-12 |
human |