| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Louise Stögbauer, Christian Thomas, Andrea Wagner, Nils Warneke, Eva Christine Bunk, Oliver Grauer, Julian Canisius, Werner Paulus, Walter Stummer, Volker Senner, Benjamin Brokinke. Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT. Journal of neurosurgery. 2021-01-15. PMID:33307532. |
efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from tert. |
2021-01-15 |
2023-08-13 |
human |
| Louise Stögbauer, Christian Thomas, Andrea Wagner, Nils Warneke, Eva Christine Bunk, Oliver Grauer, Julian Canisius, Werner Paulus, Walter Stummer, Volker Senner, Benjamin Brokinke. Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT. Journal of neurosurgery. 2021-01-15. PMID:33307532. |
human telomerase reverse transcriptase (htert) promoter methylation with subsequent tert expression and telomerase activity, key features in oncogenesis, are found in most high-grade meningiomas. |
2021-01-15 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
telomerase activity, tert expression, htert promoter alterations, and alternative lengthening of the telomeres (alt) in meningiomas - a systematic review. |
2020-11-05 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
tert expression and telomerase activity is found in benign and high-grade meningiomas and increase with who grade. |
2020-11-05 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
remarkably, rates of tert expression/telomerase activity usually exceed mutation frequency and both telomerase activity and tert expression have also been found in htert promoter wildtype meningiomas, indicating further mechanisms of tert upregulation. |
2020-11-05 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
although htert promoter methylation has been reported in the vast majority of meningiomas, correlation with tert expression remains controversial. |
2020-11-05 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
retroviral transduction of the tert gene enabled immortalization in several grade i-iii meningioma cell lines. |
2020-11-05 |
2023-08-13 |
human |
| Louise Stögbauer, Walter Stummer, Volker Senner, Benjamin Brokinke. Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review. Neurosurgical review. vol 43. issue 3. 2020-11-05. PMID:30788677. |
tert and htert promoter alterations play a major role during oncogenesis of meningiomas with implications for prognosis and potentially treatment. |
2020-11-05 |
2023-08-13 |
human |
| Christian Mirian, Anne Katrine Duun-Henriksen, Tareq Juratli, Felix Sahm, Sabine Spiegl-Kreinecker, Matthieu Peyre, Annamaria Biczok, Jörg-Christian Tonn, Stéphane Goutagny, Luca Bertero, Andrea Daniela Maier, Maria Møller Pedersen, Ian Law, Helle Broholm, Daniel P Cahill, Priscilla Brastianos, Lars Poulsgaard, Kåre Fugleholm, Morten Ziebell, Tina Munch, Tiit Mathiese. Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis. Journal of neurology, neurosurgery, and psychiatry. vol 91. issue 4. 2020-08-17. PMID:32041819. |
poor prognosis associated with tert gene alterations in meningioma is independent of the who classification: an individual patient data meta-analysis. |
2020-08-17 |
2023-08-13 |
Not clear |
| Gerhard Jungwirth, Rolf Warta, Christopher Beynon, Felix Sahm, Andreas von Deimling, Andreas Unterberg, Christel Herold-Mende, Christine Jung. Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT. Acta neuropathologica communications. vol 7. issue 1. 2020-07-30. PMID:31470906. |
intraventricular meningiomas frequently harbor nf2 mutations but lack common genetic alterations in traf7, akt1, smo, klf4, pik3ca, and tert. |
2020-07-30 |
2023-08-13 |
Not clear |
| Tareq A Juratli, Priscilla K Brastianos, Daniel P Cahil. TERT Alterations in Progressive Treatment-Resistant Meningiomas. Neurosurgery. vol 65. issue CN_suppl_1. 2019-11-20. PMID:31076787. |
tert alterations in progressive treatment-resistant meningiomas. |
2019-11-20 |
2023-08-13 |
Not clear |
| Sabine Spiegl-Kreinecker, Daniela Lötsch, Katharina Neumayer, Lucia Kastler, Johannes Gojo, Christine Pirker, Josef Pichler, Serge Weis, Rajiv Kumar, Gerald Webersinke, Andreas Gruber, Walter Berge. TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma. Neuro-oncology. vol 20. issue 12. 2019-10-18. PMID:30010853. |
tert promoter mutations are associated with poor prognosis and cell immortalization in meningioma. |
2019-10-18 |
2023-08-13 |
Not clear |
| Sabine Spiegl-Kreinecker, Daniela Lötsch, Katharina Neumayer, Lucia Kastler, Johannes Gojo, Christine Pirker, Josef Pichler, Serge Weis, Rajiv Kumar, Gerald Webersinke, Andreas Gruber, Walter Berge. TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma. Neuro-oncology. vol 20. issue 12. 2019-10-18. PMID:30010853. |
mutations in the telomerase reverse transcriptase (tert) gene promoter are comparably rare in meningioma, but were recently suggested to predict risk of recurrence and progression. |
2019-10-18 |
2023-08-13 |
Not clear |
| Sabine Spiegl-Kreinecker, Daniela Lötsch, Katharina Neumayer, Lucia Kastler, Johannes Gojo, Christine Pirker, Josef Pichler, Serge Weis, Rajiv Kumar, Gerald Webersinke, Andreas Gruber, Walter Berge. TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma. Neuro-oncology. vol 20. issue 12. 2019-10-18. PMID:30010853. |
here we have analyzed a cohort of world health organization grades i-iii meningiomas regarding the impact of tert promoter mutations on patient prognosis and in vitro cell propagation feasibility. |
2019-10-18 |
2023-08-13 |
Not clear |
| Matthieu Peyre, Guillaume Gauchotte, Marine Giry, Sébastien Froehlich, Johan Pallud, Thomas Graillon, Franck Bielle, Dominique Cazals-Hatem, Pascale Varlet, Dominique Figarella-Branger, Hugues Loiseau, Michel Kalamaride. De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors. Neuro-oncology. vol 20. issue 8. 2019-10-01. PMID:29216385. |
following recent studies underlining the differences between de novo and secondary anaplastic meningiomas and the prognostic value of telomerase reverse transcriptase (tert) promoter mutation, we decided to conduct a multicenter retrospective study to address these questions and determine specific prognostic factors in each of these 2 anaplastic meningioma subgroups. |
2019-10-01 |
2023-08-13 |
Not clear |
| Brett J Theele. De novo and secondary anaplastic meningiomas: natural history, prognosis, and the TERT promoter. Neuro-oncology. vol 20. issue 8. 2019-08-06. PMID:29982653. |
de novo and secondary anaplastic meningiomas: natural history, prognosis, and the tert promoter. |
2019-08-06 |
2023-08-13 |
Not clear |
| Victor M Lu, Anshit Goyal, Adrian Lee, Mark Jentoft, Alfredo Quinones-Hinojosa, Kaisorn L Chaichan. The prognostic significance of TERT promoter mutations in meningioma: a systematic review and meta-analysis. Journal of neuro-oncology. vol 142. issue 1. 2019-06-21. PMID:30506498. |
the prognostic significance of tert promoter mutations in meningioma: a systematic review and meta-analysis. |
2019-06-21 |
2023-08-13 |
Not clear |
| Yohei Miyake, Jun-Ichi Adachi, Tomonari Suzuki, Kazuhiko Mishima, Ryuichiro Araki, Reina Mizuno, Ryo Nishikaw. TERT promoter methylation is significantly associated with TERT upregulation and disease progression in pituitary adenomas. Journal of neuro-oncology. vol 141. issue 1. 2019-04-15. PMID:30392088. |
mutations in the tert promoter have been observed in a subset of brain tumors, including adult gliomas and high-grade meningiomas. |
2019-04-15 |
2023-08-13 |
Not clear |
| Annamaria Biczok, Theo Kraus, Bogdana Suchorska, Nicole A Terpolilli, Jun Thorsteinsdottir, Armin Giese, Joerg C Tonn, Christian Schicho. TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas. Journal of neuro-oncology. vol 139. issue 3. 2018-11-27. PMID:29808339. |
tert promoter mutation is associated with worse prognosis in who grade ii and iii meningiomas. |
2018-11-27 |
2023-08-13 |
Not clear |
| Annamaria Biczok, Theo Kraus, Bogdana Suchorska, Nicole A Terpolilli, Jun Thorsteinsdottir, Armin Giese, Joerg C Tonn, Christian Schicho. TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas. Journal of neuro-oncology. vol 139. issue 3. 2018-11-27. PMID:29808339. |
transcriptional activating mutations in the promoter region of the telomerase reverse transcriptase (tert) gene occur at high frequency in various types of solid tumors and have also been reported for meningiomas. |
2018-11-27 |
2023-08-13 |
Not clear |