| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annamaria Biczok, Theo Kraus, Bogdana Suchorska, Nicole A Terpolilli, Jun Thorsteinsdottir, Armin Giese, Joerg C Tonn, Christian Schicho. TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas. Journal of neuro-oncology. vol 139. issue 3. 2018-11-27. PMID:29808339. |
especially for atypical and anaplastic meningiomas, the prognostic relevance of tert promoter mutation is yet unclear. |
2018-11-27 |
2023-08-13 |
Not clear |
| Annamaria Biczok, Theo Kraus, Bogdana Suchorska, Nicole A Terpolilli, Jun Thorsteinsdottir, Armin Giese, Joerg C Tonn, Christian Schicho. TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas. Journal of neuro-oncology. vol 139. issue 3. 2018-11-27. PMID:29808339. |
the present study aimed to analyze the frequency of tert promoter mutation and define its long-term prognostic significance beyond clinical and histological factors in a cohort of meningiomas who grade ii and iii. |
2018-11-27 |
2023-08-13 |
Not clear |
| Akdes Serin Harmancı, Mark W Youngblood, Victoria E Clark, Süleyman Coşkun, Octavian Henegariu, Daniel Duran, E Zeynep Erson-Omay, Leon D Kaulen, Tong Ihn Lee, Brian J Abraham, Matthias Simon, Boris Krischek, Marco Timmer, Roland Goldbrunner, S Bülent Omay, Jacob Baranoski, Burçin Baran, Geneive Carrión-Grant, Hanwen Bai, Ketu Mishra-Gorur, Johannes Schramm, Jennifer Moliterno, Alexander O Vortmeyer, Kaya Bilgüvar, Katsuhito Yasuno, Richard A Young, Murat Güne. Integrated genomic analyses of de novo pathways underlying atypical meningiomas. Nature communications. vol 8. 2018-11-13. PMID:28195122. |
importantly, these primary atypical meningiomas do not harbour tert promoter mutations, which have been reported in atypical tumours that progressed from benign ones. |
2018-11-13 |
2023-08-13 |
human |
| Tanner M Johanns, Yujie Fu, Dale K Kobayashi, Yu Mei, Ian F Dunn, Diane D Mao, Albert H Kim, Gavin P Dun. High incidence of TERT mutation in brain tumor cell lines. Brain tumor pathology. vol 33. issue 3. 2017-01-19. PMID:26960334. |
to better characterize systems in which tert mutation studies could be appropriately modeled experimentally, the tert promoter was examined by conventional sequencing in primary brain tumor initiating cells (btic), two matched recurrent btic lines, a panel of established malignant glioma cell lines, and two meningioma cell lines. |
2017-01-19 |
2023-08-13 |
Not clear |
| Tanner M Johanns, Yujie Fu, Dale K Kobayashi, Yu Mei, Ian F Dunn, Diane D Mao, Albert H Kim, Gavin P Dun. High incidence of TERT mutation in brain tumor cell lines. Brain tumor pathology. vol 33. issue 3. 2017-01-19. PMID:26960334. |
the tert c228t or c250t mutation was found in 33/35 (94 %) of established malignant glioma cell lines and both meningioma cell lines examined. |
2017-01-19 |
2023-08-13 |
Not clear |
| Tanner M Johanns, Yujie Fu, Dale K Kobayashi, Yu Mei, Ian F Dunn, Diane D Mao, Albert H Kim, Gavin P Dun. High incidence of TERT mutation in brain tumor cell lines. Brain tumor pathology. vol 33. issue 3. 2017-01-19. PMID:26960334. |
thus, a high percentage of glioma cell lines, as well as two meningioma cell lines, harbors tert mutations. |
2017-01-19 |
2023-08-13 |
Not clear |
| Felix Sahm, Daniel Schrimpf, Adriana Olar, Christian Koelsche, David Reuss, Juliane Bissel, Annekathrin Kratz, David Capper, Sebastian Schefzyk, Thomas Hielscher, Qianghu Wang, Erik P Sulman, Sebastian Adeberg, Arend Koch, Ali Fuat Okuducu, Stefanie Brehmer, Jens Schittenhelm, Albert Becker, Benjamin Brokinkel, Melissa Schmidt, Theresa Ull, Konstantinos Gousias, Almuth Friederike Kessler, Katrin Lamszus, Jürgen Debus, Christian Mawrin, Yoo-Jin Kim, Matthias Simon, Ralf Ketter, Werner Paulus, Kenneth D Aldape, Christel Herold-Mende, Andreas von Deimlin. TERT Promoter Mutations and Risk of Recurrence in Meningioma. Journal of the National Cancer Institute. vol 108. issue 5. 2016-03-15. PMID:26668184. |
tert promoter mutations and risk of recurrence in meningioma. |
2016-03-15 |
2023-08-13 |
Not clear |
| Felix Sahm, Daniel Schrimpf, Adriana Olar, Christian Koelsche, David Reuss, Juliane Bissel, Annekathrin Kratz, David Capper, Sebastian Schefzyk, Thomas Hielscher, Qianghu Wang, Erik P Sulman, Sebastian Adeberg, Arend Koch, Ali Fuat Okuducu, Stefanie Brehmer, Jens Schittenhelm, Albert Becker, Benjamin Brokinkel, Melissa Schmidt, Theresa Ull, Konstantinos Gousias, Almuth Friederike Kessler, Katrin Lamszus, Jürgen Debus, Christian Mawrin, Yoo-Jin Kim, Matthias Simon, Ralf Ketter, Werner Paulus, Kenneth D Aldape, Christel Herold-Mende, Andreas von Deimlin. TERT Promoter Mutations and Risk of Recurrence in Meningioma. Journal of the National Cancer Institute. vol 108. issue 5. 2016-03-15. PMID:26668184. |
here, we assessed the tert promoter for mutations in the hotspot regions c228t and c250t in meningioma samples from 252 patients. |
2016-03-15 |
2023-08-13 |
Not clear |
| Felix Sahm, Daniel Schrimpf, Adriana Olar, Christian Koelsche, David Reuss, Juliane Bissel, Annekathrin Kratz, David Capper, Sebastian Schefzyk, Thomas Hielscher, Qianghu Wang, Erik P Sulman, Sebastian Adeberg, Arend Koch, Ali Fuat Okuducu, Stefanie Brehmer, Jens Schittenhelm, Albert Becker, Benjamin Brokinkel, Melissa Schmidt, Theresa Ull, Konstantinos Gousias, Almuth Friederike Kessler, Katrin Lamszus, Jürgen Debus, Christian Mawrin, Yoo-Jin Kim, Matthias Simon, Ralf Ketter, Werner Paulus, Kenneth D Aldape, Christel Herold-Mende, Andreas von Deimlin. TERT Promoter Mutations and Risk of Recurrence in Meningioma. Journal of the National Cancer Institute. vol 108. issue 5. 2016-03-15. PMID:26668184. |
our results indicate that the inclusion of molecular data (ie, analysis of tert promoter status) into a histologically and genetically integrated classification and grading system for meningiomas increases prognostic power. |
2016-03-15 |
2023-08-13 |
Not clear |
| Felix Sahm, Daniel Schrimpf, Adriana Olar, Christian Koelsche, David Reuss, Juliane Bissel, Annekathrin Kratz, David Capper, Sebastian Schefzyk, Thomas Hielscher, Qianghu Wang, Erik P Sulman, Sebastian Adeberg, Arend Koch, Ali Fuat Okuducu, Stefanie Brehmer, Jens Schittenhelm, Albert Becker, Benjamin Brokinkel, Melissa Schmidt, Theresa Ull, Konstantinos Gousias, Almuth Friederike Kessler, Katrin Lamszus, Jürgen Debus, Christian Mawrin, Yoo-Jin Kim, Matthias Simon, Ralf Ketter, Werner Paulus, Kenneth D Aldape, Christel Herold-Mende, Andreas von Deimlin. TERT Promoter Mutations and Risk of Recurrence in Meningioma. Journal of the National Cancer Institute. vol 108. issue 5. 2016-03-15. PMID:26668184. |
consequently, we propose to incorporate the assessment of tert promoter status in upcoming grading schemes for meningioma. |
2016-03-15 |
2023-08-13 |
Not clear |
| Malak S Abedalthagafi, Wenya Linda Bi, Parker H Merrill, William J Gibson, Matthew F Rose, Ziming Du, Joshua M Francis, Rose Du, Ian F Dunn, Azra H Ligon, Rameen Beroukhim, Sandro Santagat. ARID1A and TERT promoter mutations in dedifferentiated meningioma. Cancer genetics. vol 208. issue 6. 2015-10-27. PMID:25963524. |
arid1a and tert promoter mutations in dedifferentiated meningioma. |
2015-10-27 |
2023-08-13 |
Not clear |
| Stéphane Goutagny, Jean C Nault, Maxime Mallet, Dominique Henin, Jessica Z Rossi, Michel Kalamaride. High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain pathology (Zurich, Switzerland). vol 24. issue 2. 2015-02-21. PMID:24261697. |
high incidence of activating tert promoter mutations in meningiomas undergoing malignant progression. |
2015-02-21 |
2023-08-12 |
Not clear |
| Stéphane Goutagny, Jean C Nault, Maxime Mallet, Dominique Henin, Jessica Z Rossi, Michel Kalamaride. High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain pathology (Zurich, Switzerland). vol 24. issue 2. 2015-02-21. PMID:24261697. |
we sequenced the tert promoter in 85 meningiomas from 73 patients. |
2015-02-21 |
2023-08-12 |
Not clear |
| Stéphane Goutagny, Jean C Nault, Maxime Mallet, Dominique Henin, Jessica Z Rossi, Michel Kalamaride. High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain pathology (Zurich, Switzerland). vol 24. issue 2. 2015-02-21. PMID:24261697. |
we found a high incidence of tert promoter mutations in patients with meningiomas undergoing malignant histological progression (28%, n = 5/18 patients). |
2015-02-21 |
2023-08-12 |
Not clear |
| Stéphane Goutagny, Jean C Nault, Maxime Mallet, Dominique Henin, Jessica Z Rossi, Michel Kalamaride. High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain pathology (Zurich, Switzerland). vol 24. issue 2. 2015-02-21. PMID:24261697. |
thus, tert promoter mutations are pivotal genetic alterations involved in malignant progression of meningiomas and could be used as a biomarker to identify meningiomas at risk of malignant transformation. |
2015-02-21 |
2023-08-12 |
Not clear |