| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyu Sun, Zhongkui Xiong, Yongfang Zhang, Ya Meng, Gang Xu, Zhiming Xia, Jiamei Li, Rui Zhang, Zunji Ke, Zongqin Xia, Yaer H. Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor. Journal of neurochemistry. vol 120. issue 6. 2012-06-01. PMID:22192054. |
parkinson's disease is a chronic neurodegenerative movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. |
2012-06-01 |
2023-08-12 |
mouse |
| P R Mouton, B Kelley-Bell, D Tweedie, E L Spangler, E Perez, O D Carlson, R G Short, R deCabo, J Chang, D K Ingram, Y Li, N H Grei. The effects of age and lipopolysaccharide (LPS)-mediated peripheral inflammation on numbers of central catecholaminergic neurons. Neurobiology of aging. vol 33. issue 2. 2012-04-19. PMID:21093964. |
parkinson's disease (pd), an age-related movement disorder, is characterized by severe catecholaminergic neuron loss in the substantia nigra pars compacta (sn(pc))-ventral tegmental area (vta) and locus coeruleus (lc). |
2012-04-19 |
2023-08-12 |
mouse |
| S K Kalia, L V Kalia, P J McLea. Molecular chaperones as rational drug targets for Parkinson's disease therapeutics. CNS & neurological disorders drug targets. vol 9. issue 6. 2011-02-28. PMID:20942788. |
parkinson's disease is a neurodegenerative movement disorder that is caused, in part, by the loss of dopaminergic neurons within the substantia nigra pars compacta of the basal ganglia. |
2011-02-28 |
2023-08-12 |
Not clear |
| Yuzuru Imai, Ryosuke Takahash. [Frontier researches for the development of molecular-targeted therapies for familial Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 8. 2009-11-09. PMID:19697879. |
parkinson disease (pd), is a movement disorder pathologically characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. |
2009-11-09 |
2023-08-12 |
Not clear |
| Hansruedi Büele. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease. Experimental neurology. vol 218. issue 2. 2009-09-04. PMID:19303005. |
parkinson's disease (pd), the most frequent movement disorder, is caused by the progressive loss of the dopamine neurons within the substantia nigra pars compacta (snc) and the associated deficiency of the neurotransmitter dopamine in the striatum. |
2009-09-04 |
2023-08-12 |
Not clear |
| Ruth Djaldetti, Nirit Lev, Eldad Melame. Lesions outside the CNS in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 6. 2009-07-29. PMID:19224610. |
parkinson's disease (pd) is not a simple movement disorder induced just by loss of dopaminergic neurons in the substantia nigra pars compacta. |
2009-07-29 |
2023-08-12 |
Not clear |
| Rong Ying, Huan Ling Liang, Harry T Whelan, Janis T Eells, Margaret T T Wong-Rile. Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity. Brain research. vol 1243. 2009-01-21. PMID:18848925. |
parkinson's disease (pd) is a movement disorder caused by the loss of dopaminergic neurons in the substantia nigra pars compacta, leading to nigrostriatal degeneration. |
2009-01-21 |
2023-08-12 |
rat |
| Alicja Lerner, Anto Bagi. Olfactory pathogenesis of idiopathic Parkinson disease revisited. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 8. 2008-10-20. PMID:18442121. |
idiopathic parkinson disease (pd) is traditionally considered a movement disorder with hallmark lesions located in the substantia nigra pars compacta (snpc). |
2008-10-20 |
2023-08-12 |
Not clear |
| Eusebio Lavara-Culebras, Nuria Parici. Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits. Gene. vol 400. issue 1-2. 2007-11-05. PMID:17651920. |
parkinson's disease (pd) is a progressive movement disorder caused by the selective and massive loss of dopaminergic neurons (da) in the substantia nigra pars compacta (snc). |
2007-11-05 |
2023-08-12 |
mouse |
| S M Smits, S van der Nobelen, K J M Hornman, L von Oerthel, J P H Burbach, M P Smid. Signalling through phospholipase C beta 4 is not essential for midbrain dopaminergic neuron survival. Neuroscience. vol 136. issue 1. 2006-02-14. PMID:16198487. |
the most prominent progressive neurodegenerative movement disorder, parkinson's disease, is attributed to selective loss of dopamine neurons in the substantia nigra pars compacta, resulting in severe deficiency of dopamine. |
2006-02-14 |
2023-08-12 |
mouse |
| H Fai Poon, Mark Frasier, Nathan Shreve, Vittorio Calabrese, Benjamin Wolozin, D Allan Butterfiel. Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiology of disease. vol 18. issue 3. 2005-05-17. PMID:15755676. |
parkinson's disease (pd) is the most common neurodegenerative movement disorder and is characterized by the loss of dopaminergic neurons in the substantia nigra compacta. |
2005-05-17 |
2023-08-12 |
human |
| T Nagatsu, M Sawad. Inflammatory process in Parkinson's disease: role for cytokines. Current pharmaceutical design. vol 11. issue 8. 2005-04-06. PMID:15777250. |
parkinson's disease (pd) is a movement disorder caused by degeneration of the nigrostriatal dopamine (da) neurons in the substantia nigra pars compacta and the resultant deficiency in the neurotransmitter da at the nerve terminals in the striatum. |
2005-04-06 |
2023-08-12 |
Not clear |
| Jason L Eriksen, Zbigniew Wszolek, Leonard Petrucell. Molecular pathogenesis of Parkinson disease. Archives of neurology. vol 62. issue 3. 2005-04-05. PMID:15767499. |
parkinson disease (pd), the most common neurodegenerative movement disorder, is characterized by an extensive and progressive loss of dopaminergic neurons in the substantia nigra pars compacta. |
2005-04-05 |
2023-08-12 |
Not clear |
| Timothy Brown, Carmen de Groote, Jonathan Brotchi. Recent advances in the treatment of L-DOPA-induced dyskinesia. IDrugs : the investigational drugs journal. vol 5. issue 5. 2005-03-28. PMID:15570465. |
parkinson's disease (pd) is a degenerative movement disorder resulting from the loss of dopaminergic neurons in the substantia nigra pars compacta. |
2005-03-28 |
2023-08-12 |
Not clear |
| Rainer Von Coelln, Bobby Thomas, Joseph M Savitt, Kah Leong Lim, Masayuki Sasaki, Ellen J Hess, Valina L Dawson, Ted M Dawso. Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 29. 2004-08-26. PMID:15249681. |
parkinson's disease (pd) is the most common neurodegenerative movement disorder and is characterized pathologically by degeneration of catecholaminergic neurons of the substantia nigra pars compacta and locus coeruleus, among other regions. |
2004-08-26 |
2023-08-12 |
mouse |
| Michael J Marino, Ornella Valenti, P Jeffrey Con. Glutamate receptors and Parkinson's disease: opportunities for intervention. Drugs & aging. vol 20. issue 5. 2004-02-19. PMID:12696997. |
parkinson's disease is a debilitating neurodegenerative movement disorder that is the result of a degeneration of dopaminergic neurons in the substantia nigra pars compacta. |
2004-02-19 |
2023-08-12 |
Not clear |
| Aaron C Pawlyk, Benoit I Giasson, Deepak M Sampathu, Francisco A Perez, Kah Leong Lim, Valina L Dawson, Ted M Dawson, Richard D Palmiter, John Q Trojanowski, Virginia M-Y Le. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. The Journal of biological chemistry. vol 278. issue 48. 2004-01-12. PMID:12972409. |
autosomal recessive juvenile parkinsonism is a movement disorder associated with the degeneration of dopaminergic neurons in substantia nigra pars compacta. |
2004-01-12 |
2023-08-12 |
mouse |
| Pavan K Auluck, H Y Edwin Chan, John Q Trojanowski, Virginia M Y Lee, Nancy M Bonin. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science (New York, N.Y.). vol 295. issue 5556. 2002-02-20. PMID:11823645. |
parkinson's disease is a movement disorder characterized by degeneration of dopaminergic neurons in the substantia nigra pars compacta. |
2002-02-20 |
2023-08-12 |
human |
| R M Bonelli, L Kenner, A Gruber, F Reisecker, P Költringe. Compactotomy in Huntington's chorea. Medical hypotheses. vol 57. issue 4. 2002-01-24. PMID:11601877. |
we postulate that deep brain stimulation of the substantia nigra pars compacta may ameliorate hyperkinesia in choreatic movement disorders, thus representing the first effective therapy in huntington's chorea. |
2002-01-24 |
2023-08-12 |
Not clear |
| T Deacon, J Schumacher, J Dinsmore, C Thomas, P Palmer, S Kott, A Edge, D Penney, S Kassissieh, P Dempsey, O Isacso. Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease. Nature medicine. vol 3. issue 3. 1997-04-01. PMID:9055867. |
the movement disorder in parkinson's disease results from the selective degeneration of a small group of dopaminergic neurons in the substantia nigra pars compacta region of the brain. |
1997-04-01 |
2023-08-12 |
human |