| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhongxing Zhang, Jari K Gool, Rolf Fronczek, Yves Dauvilliers, Claudio L A Bassetti, Geert Mayer, Giuseppe Plazzi, Fabio Pizza, Joan Santamaria, Markku Partinen, Sebastiaan Overeem, Rosa Peraita-Adrados, Antonio Martins da Silva, Karel Sonka, Rafael Del Rio-Villegas, Raphael Heinzer, Aleksandra Wierzbicka, Peter Young, Birgit Högl, Mauro Manconi, Eva Feketeova, Johannes Mathis, Teresa Paiva, Francesca Canellas, Michel Lecendreux, Christian R Baumann, Gert Jan Lammers, Ramin Khatam. New 2013 incidence peak in childhood narcolepsy: more than vaccination? Sleep. vol 44. issue 2. 2021-04-26. PMID:32909046. |
increased incidence rates of narcolepsy type-1 (nt1) have been reported worldwide after the 2009-2010 h1n1 influenza pandemic (ph1n1). |
2021-04-26 |
2023-08-13 |
Not clear |
| Zhongxing Zhang, Jari K Gool, Rolf Fronczek, Yves Dauvilliers, Claudio L A Bassetti, Geert Mayer, Giuseppe Plazzi, Fabio Pizza, Joan Santamaria, Markku Partinen, Sebastiaan Overeem, Rosa Peraita-Adrados, Antonio Martins da Silva, Karel Sonka, Rafael Del Rio-Villegas, Raphael Heinzer, Aleksandra Wierzbicka, Peter Young, Birgit Högl, Mauro Manconi, Eva Feketeova, Johannes Mathis, Teresa Paiva, Francesca Canellas, Michel Lecendreux, Christian R Baumann, Gert Jan Lammers, Ramin Khatam. New 2013 incidence peak in childhood narcolepsy: more than vaccination? Sleep. vol 44. issue 2. 2021-04-26. PMID:32909046. |
using robust data-driven modeling approaches, that is, locally estimated scatterplot smoothing methods, we analyzed the number of de novo nt1 cases (n = 508) in the last two decades using the european narcolepsy network database. |
2021-04-26 |
2023-08-13 |
Not clear |
| Zhongxing Zhang, Jari K Gool, Rolf Fronczek, Yves Dauvilliers, Claudio L A Bassetti, Geert Mayer, Giuseppe Plazzi, Fabio Pizza, Joan Santamaria, Markku Partinen, Sebastiaan Overeem, Rosa Peraita-Adrados, Antonio Martins da Silva, Karel Sonka, Rafael Del Rio-Villegas, Raphael Heinzer, Aleksandra Wierzbicka, Peter Young, Birgit Högl, Mauro Manconi, Eva Feketeova, Johannes Mathis, Teresa Paiva, Francesca Canellas, Michel Lecendreux, Christian R Baumann, Gert Jan Lammers, Ramin Khatam. New 2013 incidence peak in childhood narcolepsy: more than vaccination? Sleep. vol 44. issue 2. 2021-04-26. PMID:32909046. |
our results suggest that the increased nt1 incidence after 2009-2010 ph1n1 is not unique and our study provides an opportunity to develop new hypotheses, for example, considering other (influenza) viruses or epidemiological events to further investigate the pathophysiology of immune-mediated narcolepsy. |
2021-04-26 |
2023-08-13 |
Not clear |
| Alessandro Silvani, Stefano Vandi, Fabio Pizza, Elena Antelmi, Raffaele Ferri, Giuseppe Plazz. Combining information on nocturnal rapid eye movement sleep latency and atonia to facilitate diagnosis of pediatric narcolepsy type 1. Sleep. vol 44. issue 3. 2021-04-26. PMID:33035342. |
the diagnosis of narcolepsy type 1 (nt1) at its onset in children and adolescents is often difficult, with substantial diagnostic delay. |
2021-04-26 |
2023-08-13 |
Not clear |
| Peipei Wang, Qinghua Li, Xiaosong Dong, Haiyan An, Jing Li, Long Zhao, Han Yan, Kosuke Aritake, Zhili Huang, Kingman P Strohl, Yoshihiro Urade, Jun Zhang, Fang Ha. Lipocalin-type prostaglandin D synthase levels increase in patients with narcolepsy and idiopathic hypersomnia. Sleep. vol 44. issue 4. 2021-04-26. PMID:33175978. |
this study is to compare cerebral spinal fluid (csf) and serum lpgds levels in patients group with hypersomnia of central origin, including those with narcolepsy type 1 (nt1) and type 2 (nt2) and ih, to those in healthy controls (con). |
2021-04-26 |
2023-08-13 |
Not clear |
| Alexander Lind, Falastin Salami, Anne-Marie Landtblom, Lars Palm, Åke Lernmark, Jörgen Adolfsson, Helena Elding Larsso. Immunocyte single cell analysis of vaccine-induced narcolepsy. European journal of immunology. vol 51. issue 1. 2021-04-22. PMID:32671842. |
increased incidence of narcolepsy type 1 (nt1) was observed following pandemrix®-vaccination, initiated as a preventive measure against the 2009 influenza pandemic. |
2021-04-22 |
2023-08-13 |
Not clear |
| Lucie Barateau, Sofiene Chenini, Manuela Lotierzo, Anna Laura Rassu, Elisa Evangelista, Régis Lopez, Anne-Marie Gorce Dupuy, Isabelle Jaussent, Yves Dauvillier. CSF and serum ferritin levels in narcolepsy type 1 comorbid with restless legs syndrome. Annals of clinical and translational neurology. vol 7. issue 6. 2021-04-19. PMID:32432412. |
to investigate whether cerebrospinal fluid (csf) and serum ferritin levels differ between patients with narcolepsy type 1 (nt1) comorbid with restless legs syndrome (rls) or periodic leg movements during sleep (plms), and patients with nt1 or controls without comorbid rls or plms. |
2021-04-19 |
2023-08-13 |
Not clear |
| Simone Baiardi, Fabio Pizza, Barbara Polischi, Monica Moresco, Samir Abu-Rumeileh, Giuseppe Plazzi, Piero Parch. Cerebrospinal fluid biomarkers of neurodegeneration in narcolepsy type 1. Sleep. vol 43. issue 2. 2021-04-14. PMID:31552425. |
to measure the levels of five neurodegenerative biomarkers in the cerebrospinal fluid (csf) of patients with narcolepsy type 1 (nt1) with variable disease duration. |
2021-04-14 |
2023-08-13 |
Not clear |
| Hilde T Juvodden, Marte K Viken, Sebjørg E H Nordstrand, Rannveig Viste, Lars T Westlye, Per M Thorsby, Benedicte A Lie, Stine Knudsen-Heie. HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives. Sleep. vol 43. issue 3. 2021-04-14. PMID:31606740. |
to explore hla (human leukocyte antigen) in post-h1n1 narcolepsy type 1 patients (nt1), first-degree relatives and healthy controls, and assess hla associations with clinical and sleep parameters in patients and first-degree relatives. |
2021-04-14 |
2023-08-13 |
human |
| Sebjørg E H Nordstrand, Hilde T Juvodden, Rannveig Viste, Terje Rootwelt, Tor-Ivar Karlsen, Per M Thorsby, David Swanson, Kristian Bernhard Nilsen, Berit H Hansen, Stine Knudsen-Heie. Obesity and other medical comorbidities among NT1 patients after the Norwegian H1N1 influenza epidemic and vaccination campaign. Sleep. vol 43. issue 5. 2021-04-14. PMID:31724727. |
narcolepsy type 1 (nt1) may be complicated by comorbidities. |
2021-04-14 |
2023-08-13 |
Not clear |
| Carlo Cipolli, Fabio Pizza, Claudia Bellucci, Michela Mazzetti, Giovanni Tuozzi, Stefano Vandi, Giuseppe Plazz. Structural organization of dream experience during daytime sleep-onset rapid eye movement period sleep of patients with narcolepsy type 1. Sleep. vol 43. issue 8. 2021-04-14. PMID:32055854. |
to assess the frequency of dream experience (de) developed during naps at multiple sleep latency test (mslt) by patients with narcolepsy type 1 (nt1) and establish, using story-grammar analysis, the structural organization of des developed during naps with sleep onset rapid eye movement (rem) period (soremp) sleep compared with their des during early- and late-night rem sleep. |
2021-04-14 |
2023-08-13 |
Not clear |
| Kiran Maski, Fabio Pizza, Shanshan Liu, Erin Steinhart, Elaina Little, Alicia Colclasure, Cecilia Diniz Behn, Stefano Vandi, Elena Antelmi, Edie Weller, Thomas E Scammell, Giuseppe Plazz. Defining disrupted nighttime sleep and assessing its diagnostic utility for pediatric narcolepsy type 1. Sleep. vol 43. issue 10. 2021-04-14. PMID:32253429. |
in this study, we define a dns objective measure and evaluate its diagnostic utility for pediatric narcolepsy type 1 (nt1). |
2021-04-14 |
2023-08-13 |
Not clear |
| Mihoko Shimada, Taku Miyagawa, Tohru Kodama, Hiromi Toyoda, Katsushi Tokunaga, Makoto Hond. Metabolome analysis using cerebrospinal fluid from narcolepsy type 1 patients. Sleep. vol 43. issue 11. 2021-04-14. PMID:32412602. |
narcolepsy type 1 (nt1) is a hypersomnia characterized by excessive daytime sleepiness and cataplexy. |
2021-04-14 |
2023-08-13 |
human |
| Karin A M Janssens, Laury Quaedackers, Gert Jan Lammers, Pauline Amesz, Petra van Mierlo, Lisanne Aarts, Els Peeters, Danielle Hendriks, Nele Vandenbussche, Sebastiaan Overeem, Sigrid Pille. Effect of treatment on cognitive and attention problems in children with narcolepsy type 1. Sleep. vol 43. issue 12. 2021-04-14. PMID:32505131. |
to ascertain the presence of cognitive and attention problems in treatment naïve children with narcolepsy type 1 (nt1) and to explore whether children recently diagnosed with nt1 improve with respect to cognition and attention problems 1 year after regular treatment for nt1. |
2021-04-14 |
2023-08-13 |
Not clear |
| Marco Filardi, Vincenza Blunda, Stefano Vandi, Alessandro Musetti, Annio Posar, Paola Visconti, Fabio Pizza, Giuseppe Plazzi, Christian Franceschin. Case Report: Burden of Illness in Narcolepsy Type 1: Hikikomori in a Teenage Girl. Frontiers in psychology. vol 12. 2021-03-30. PMID:33776861. |
narcolepsy type 1 (nt1) deeply impacts on quality of life, especially during adolescence, with nt1 children and adolescents that frequently report difficulties in integration with peers and decreased participation in after-school activities. |
2021-03-30 |
2023-08-13 |
Not clear |
| Maeve Pascoe, James Bena, Nancy Foldvary-Schaefe. Effects of Pharmacotherapy Treatment on Patient-Reported Outcomes in a Narcolepsy and Idiopathic Hypersomnia Cohort. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 15. issue 12. 2021-03-22. PMID:31855165. |
we aimed to evaluate the association between patient-reported outcomes (pros) and treatment regimen/standardized dose (std), a measure of drug burden, in patients with narcolepsy type 1 (nt1)/type 2 (nt2) and idiopathic hypersomnia (ih). |
2021-03-22 |
2023-08-13 |
Not clear |
| Anna A Rogers, Lauren M Aiani, Lou T Blanpain, Sun Yuxian, Renee Moore, Jon T Willi. Deep brain stimulation of hypothalamus for narcolepsy-cataplexy in mice. Brain stimulation. vol 13. issue 5. 2021-03-22. PMID:32320748. |
narcolepsy type 1 (nt1, narcolepsy with cataplexy) is a disabling neurological disorder caused by loss of excitatory orexin neurons from the hypothalamus and is characterized by decreased motivation, sleep-wake fragmentation, intrusion of rapid-eye-movement sleep (rems) during wake, and abrupt loss of muscle tone, called cataplexy, in response to sudden emotions. |
2021-03-22 |
2023-08-13 |
mouse |
| Chuan Hong, Noel J Byrne, Beata Zamlynny, Srivanya Tummala, Li Xiao, Jennifer M Shipman, Andrea T Partridge, Christina Minnick, Michael J Breslin, Michael T Rudd, Shawn J Stachel, Vanessa L Rada, Jeffrey C Kern, Kira A Armacost, Scott A Hollingsworth, Julie A O'Brien, Dawn L Hall, Terrence P McDonald, Corey Strickland, Alexei Brooun, Stephen M Soisson, Kaspar Hollenstei. Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. Nature communications. vol 12. issue 1. 2021-02-17. PMID:33547286. |
narcolepsy type 1 (nt1) is a chronic neurological disorder that impairs the brain's ability to control sleep-wake cycles. |
2021-02-17 |
2023-08-13 |
Not clear |
| Elena Antelmi, Fabio Pizza, Christian Franceschini, Raffaele Ferri, Giuseppe Plazz. REM sleep behavior disorder in narcolepsy: A secondary form or an intrinsic feature? Sleep medicine reviews. vol 50. 2021-02-08. PMID:31931470. |
rbd reportedly affects 30-60% of patients with narcolepsy type 1 (nt1), but it may be seen also in narcolepsy type 2 (nt2). |
2021-02-08 |
2023-08-13 |
Not clear |
| Emanuela Postiglione, Fabio Pizza, Francesca Ingravallo, Luca Vignatelli, Marco Filardi, Anastasia Mangiaruga, Elena Antelmi, Monica Moresco, Claudia Oriolo, Uberto Pagotto, Giuseppe Plazz. Impact of COVID-19 pandemic lockdown on narcolepsy type 1 management. Brain and behavior. vol 11. issue 1. 2021-02-08. PMID:33247632. |
narcolepsy type 1 (nt1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. |
2021-02-08 |
2023-08-13 |
Not clear |