| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucie Barateau, Régis Lopez, Sofiene Chenini, Anna Laura Rassu, Lytissia Mouhli, Cloé Dhalluin, Isabelle Jaussent, Yves Dauvillier. Linking clinical complaints and objective measures of Disrupted Nighttime Sleep in Narcolepsy type 1. Sleep. 2022-03-11. PMID:35275598. |
despite its high frequency in narcolepsy type 1(nt1), disrupted nocturnal sleep (dns) remains understudied, and its determinants have been poorly assessed. |
2022-03-11 |
2023-08-13 |
Not clear |
| Louise Piilgaard, Laura Rose, Camille Gylling Hviid, Kristi A Kohlmeier, Birgitte Rahbek Kornu. Sex-related differences within sleep-wake dynamics, cataplexy, and EEG fast-delta power in a narcolepsy mouse model. Sleep. 2022-03-10. PMID:35266540. |
narcolepsy type 1 (nt1) is a sleep-wake disorder caused by selective loss of hypocretin (hcrt, also called orexin) neurons. |
2022-03-10 |
2023-08-13 |
mouse |
| Adrienne Elisabeth van der Hoeven, Rolf Fronczek, Mink Sebastian Schinkelshoek, Frederik Willem Cornelis Roelandse, Jaap Adriaan Bakker, Sebastiaan Overeem, Denise Bijlenga, Gert Jan Lammer. Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1. Sleep. 2022-03-07. PMID:35255144. |
the diagnosis of narcolepsy type 1 (nt1) is based upon the presence of cataplexy and/or a cerebrospinal fluid (csf) hypocretin-1/orexin-a level ≤110 pg/ml. |
2022-03-07 |
2023-08-13 |
Not clear |
| Yu Sun, Ryan Tisdale, Sunmee Park, Shun-Chieh Ma, Jasmine Heu, Meghan Haire, Giancarlo Allocca, Akihiro Yamanaka, Stephen R Morairty, Thomas S Kilduf. The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice. Sleep. 2022-02-19. PMID:35182424. |
narcolepsy type 1 (nt1), a sleep disorder with similar prevalence in both sexes, is thought to be due to loss of the hypocretin/orexin (hcrt) neurons. |
2022-02-19 |
2023-08-13 |
mouse |
| Kunlin Ni, Yishu Liu, Xiaoyu Zhu, Huiwen Tan, Yin Zeng, Qiyong Guo, Li Xiao, Bing Y. Changed Cerebral White Matter Structural Network Topological Characters and Its Correlation with Cognitive Behavioral Abnormalities in Narcolepsy Type 1. Nature and science of sleep. vol 14. 2022-02-10. PMID:35140538. |
in the current study we investigated topological abnormalities of the cerebral white matter networks in narcolepsy type 1 (nt1) patients and its relationship with their cognitive abnormalities using diffusion tensor imaging (dti) technology. |
2022-02-10 |
2023-08-13 |
Not clear |
| Chenyang Li, Liang Xie, Shaomei Shang, Xiaosong Dong, Jun Zhang, Yinghui Gao, Fang Ha. The Impact of Symptom Severity on Health-Related Quality of Life in People with Narcolepsy Type 1. Behavioral sleep medicine. 2022-01-21. PMID:35061552. |
to assess the impact of symptom severity on health-related quality of life (hrqol) in people with narcolepsy type 1 (nt1). |
2022-01-21 |
2023-08-13 |
Not clear |
| Leonardo Caporali, Monica Moresco, Fabio Pizza, Chiara La Morgia, Claudio Fiorini, Daniela Strobbe, Corrado Zenesini, Baharak Hooshiar Kashani, Antonio Torroni, Uberto Pagotto, Valerio Carelli, Giuseppe Plazz. The role of mtDNA haplogroups on metabolic features in narcolepsy type 1. Mitochondrion. 2022-01-20. PMID:35051655. |
narcolepsy type 1 (nt1) is due to selective loss of hypocretin (hcrt)-producing-neurons. |
2022-01-20 |
2023-08-13 |
Not clear |
| Smaranda Leu-Semenescu, Jean-Baptiste Maranci, Regis Lopez, Xavier Drouot, Pauline Dodet, Ana Gales, Elisabeth Groos, Lucie Barateau, Patricia Franco, Michel Lecendreux, Yves Dauvilliers, Isabelle Arnul. Comorbid parasomnias in narcolepsy and idiopathic hypersomnia: more REM than NREM parasomnias. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2022-01-05. PMID:34984974. |
to assess the frequency, determinants and clinical impact of clinical nrem and rem parasomnias in adult patients with narcolepsy type 1 (nt1), narcolepsy type 2 (nt2), and idiopathic hypersomnia (ih) compared to healthy controls. |
2022-01-05 |
2023-08-13 |
Not clear |
| Ling Shan, Rawien Balesar, Dick F Swaab, Gert Jan Lammers, Rolf Froncze. Reduced numbers of corticotropin-releasing hormone neurons in narcolepsy type 1. Annals of neurology. 2022-01-04. PMID:34981555. |
narcolepsy type 1 (nt1) is a chronic sleep disorder correlated with loss of hypocretin(orexin). |
2022-01-04 |
2023-08-13 |
Not clear |
| Vortioxetine Effects on Sleep Architecture in Treatment of Comorbid Depression in Adolescent Patient with Narcolepsy and Cataplexy: Case Report. Neuro endocrinology letters. vol 42. issue 8. 2021-12-30. PMID:34969190. |
this report presents a rare case of adolescent patient treated by novel antidepressant vortioxetine for depressive disorder comorbid to narcolepsy type 1 (nt1) and newly diagnosed rem behavior disorder (rbd) and describes the overall clinical improvement of the conditions. |
2021-12-30 |
2023-08-13 |
Not clear |
| Dauvilliers Yves, Lucie Barateau, Benita Middleton, Daan Van Der Veen, Debra J Sken. Metabolomic Signature of Patients With Narcolepsy. Neurology. 2021-11-30. PMID:34845055. |
narcolepsy type 1 (nt1) is an orphan brain disorder caused by the irreversible destruction of orexin neurons. |
2021-11-30 |
2023-08-13 |
Not clear |
| Emmanuel Mignot, Jamie Zeitzer, Fabio Pizza, Giuseppe Plazz. Sleep Problems in Narcolepsy and the Role of Hypocretin/Orexin Deficiency. Frontiers of neurology and neuroscience. vol 45. 2021-11-29. PMID:34052809. |
since its description in the 19th century, narcolepsy type 1 (nt1) has been considered as a model sleep disorder, and after the discovery of rapid eye movement (rem) sleep onset in the disorder, a gateway to understanding rem sleep. |
2021-11-29 |
2023-08-13 |
human |
| Yoo Hyun Um, Jihye Oh, Sung-Min Kim, Tae-Won Kim, Ho-Jun Seo, Jong-Hyun Jeong, Seung-Chul Hon. Differential characteristics of repeated polysomnography and multiple sleep latency test parameters in narcolepsy type 1 and type 2 patients: a longitudinal retrospective study. Sleep & breathing = Schlaf & Atmung. 2021-11-25. PMID:34820763. |
narcolepsy is a chronic disorder and its phenotype is dichotomized into narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2). |
2021-11-25 |
2023-08-13 |
Not clear |
| Poul Jørgen Jennum, Giuseppe Plazzi, Alessandro Silvani, Lee A Surkin, Yves Dauvillier. Cardiovascular disorders in narcolepsy: Review of associations and determinants. Sleep medicine reviews. vol 58. 2021-11-22. PMID:33582582. |
narcolepsy type 1 (nt1) is a lifelong disorder of sleep-wake dysregulation defined by clinical symptoms, neurophysiological findings, and low hypocretin levels. |
2021-11-22 |
2023-08-13 |
Not clear |
| Marco Filardi, Anita D'Anselmo, Sergio Agnoli, Enrico Rubaltelli, Serena Mastria, Anastasia Mangiaruga, Christian Franceschini, Fabio Pizza, Giovanni E Corazza, Giuseppe Plazz. Cognitive dysfunction in central disorders of hypersomnolence: A systematic review. Sleep medicine reviews. vol 59. 2021-11-22. PMID:34166991. |
forty-eight studies proved eligible and were analyzed separately for narcolepsy type 1 (nt1), narcolepsy type 2 (nt2), idiopathic hypersomnia (ih) and kleine-levin syndrome (kls). |
2021-11-22 |
2023-08-13 |
Not clear |
| Ruirui Zhang, Shanjun Gao, Shenghui Wang, Jiewen Zhang, Yingying Bai, Shuang He, Pan Zhao, Hongju Zhan. Gut Microbiota in Patients with Type 1 Narcolepsy. Nature and science of sleep. vol 13. 2021-11-18. PMID:34785965. |
to explore the characteristics of gut microbiota and its relationship between clinical manifestations in patients with type 1 narcolepsy (nt1). |
2021-11-18 |
2023-08-13 |
Not clear |
| Alexander Lind, Ilaria Marzinotto, Cristina Brigatti, Anita Ramelius, Lorenzo Piemonti, Vito Lampason. A/H1N1 hemagglutinin antibodies show comparable affinity in vaccine-related Narcolepsy type 1 and control and are unlikely to contribute to pathogenesis. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33603024. |
an increased incidence of narcolepsy type 1 (nt1) was observed in scandinavia following the 2009-2010 influenza pandemrix vaccination. |
2021-11-15 |
2023-08-13 |
Not clear |
| Denise Bijlenga, Bram Urbanus, Nick N J J M van der Sluiszen, Sebastiaan Overeem, Jan G Ramaekers, Annemiek Vermeeren, Gert Jan Lammer. Comparing objective wakefulness and vigilance tests to on-the-road driving performance in narcolepsy and idiopathic hypersomnia. Journal of sleep research. 2021-11-10. PMID:34755413. |
participants were 44 patients (aged 18-75 years) with narcolepsy type 1 (nt1), type 2 (nt2) or ih. |
2021-11-10 |
2023-08-13 |
human |
| Rannveig Viste, Benedicte A Lie, Marte K Viken, Terje Rootwelt, Stine Knudsen-Heier, Birgitte R Kornu. Narcolepsy type 1 patients have lower levels of effector memory CD4 Sleep medicine. vol 85. 2021-10-28. PMID:34388506. |
narcolepsy type 1 patients have lower levels of effector memory cd4 evidence suggests a cell-mediated autoimmune pathogenesis for narcolepsy type 1 (nt1), but it is not clear whether the disease is associated with overall changes in t cell subsets. |
2021-10-28 |
2023-08-13 |
Not clear |
| Rannveig Viste, Marte K Viken, Benedicte A Lie, Hilde T Juvodden, Sebjørg E H Nordstrand, Per M Thorsby, Terje Rootwelt, Birgitte R Kornum, Stine Knudsen-Heie. High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1. Sleep. vol 44. issue 8. 2021-10-25. PMID:33710305. |
narcolepsy type 1 (nt1) is associated with hypocretin neuron loss. |
2021-10-25 |
2023-08-13 |
Not clear |