All Relations between Neurodegenerative Diseases and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Jia Liu, Weijing Liu, Hui Yan. Balancing Apoptosis and Autophagy for Parkinson's Disease Therapy: Targeting BCL-2. ACS chemical neuroscience. vol 10. issue 2. 2020-02-26. PMID:30400738. conversely, their imbalance is associated with neurodegenerative diseases such as parkinson's disease (pd), which is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. 2020-02-26 2023-08-13 Not clear
Lei-Lei Chen, Yu-Jv Huang, Jun-Tao Cui, Ning Song, Junxia Xi. Iron Dysregulation in Parkinson's Disease: Focused on the Autophagy-Lysosome Pathway. ACS chemical neuroscience. vol 10. issue 2. 2020-02-26. PMID:30590010. parkinson's disease (pd) is the second most common neurodegenerative disease and is characterized by dopaminergic neuron loss in the substantia nigra pars compacta (snpc). 2020-02-26 2023-08-13 Not clear
Pallavi Rane, Deepaneeta Sarmah, Shashikala Bhute, Harpreet Kaur, Avirag Goswami, Kiran Kalia, Anupom Borah, Kunjan R Dave, Nutan Sharma, Pallab Bhattachary. Novel Targets for Parkinson's Disease: Addressing Different Therapeutic Paradigms and Conundrums. ACS chemical neuroscience. vol 10. issue 1. 2020-02-06. PMID:29957921. parkinson's disease (pd) is a neurodegenerative disease that is pathologically characterized by degeneration of dopamine neurons in the substantia nigra pars compacta (snpc). 2020-02-06 2023-08-13 Not clear
Akira Nakajima, Yasushi Ohizum. Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease. International journal of molecular sciences. vol 20. issue 14. 2019-12-20. PMID:31295812. parkinson's disease (pd) is the second most common neurodegenerative disease after ad, and is characterized by early prominent loss of dopaminergic neurons in the substantia nigra pars compacta. 2019-12-20 2023-08-13 Not clear
Tao Peng, Xiaoyan Liu, Jingtao Wang, Yu Liu, Zhenqiang Fu, Xingrong Ma, Junmin Li, Guifang Sun, Yangfei Ji, Jingjing Lu, Wencui Wan, Hong L. Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson's disease via regulating miR-100/ATG10 axis and PI3K/Akt/mTOR pathway activation. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-12-09. PMID:31298038. parkinson's disease (pd) is a common age-related neurodegenerative disease resulted from the progressive degeneration of dopaminergic neurons in the pars compacta region of substantia nigra. 2019-12-09 2023-08-13 mouse
Saba Khanam, Yasir Hasan Siddiqu. Dopamine: Agonists and Neurodegenerative Disorders. Current drug targets. vol 19. issue 14. 2019-10-29. PMID:29149825. parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons within the substantia nigra pars compacta (snpc). 2019-10-29 2023-08-13 Not clear
Vignayanandam Ravindernath Muddapu, Alekhya Mandali, V Srinivasa Chakravarthy, Srikanth Ramaswam. A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity. Frontiers in neural circuits. vol 13. 2019-07-16. PMID:30858799. parkinson's disease (pd) is a neurodegenerative disease associated with progressive and inexorable loss of dopaminergic cells in substantia nigra pars compacta (snc). 2019-07-16 2023-08-13 Not clear
Zhou Zhu, Chuanbin Yang, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Sravan Gopalkrishnashetty Sreenivasmurthy, Jia Liu, Ziying Wang, Benjamin Chun-Kit Tong, Juxian Song, Jiahong Lu, King-Ho Cheung, Min L. Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson's Disease. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30744070. parkinson's disease (pd) is a serious, common neurodegenerative disease characterized by dopaminergic neuron loss in the substantia nigra pars compacta (snpc) and the accumulation of lewy bodies. 2019-05-29 2023-08-13 Not clear
Shahram Darabi, Ali Noori-Zadeh, Farzad Rajaei, Hojjat Allah Abbaszadeh, Salar Bakhtiyari, Navid Ahmady Roozbahan. SMER28 Attenuates Dopaminergic Toxicity Mediated by 6-Hydroxydopamine in the Rats via Modulating Oxidative Burdens and Autophagy-Related Parameters. Neurochemical research. vol 43. issue 12. 2019-05-23. PMID:30288644. parkinson's disease is the second most common neurodegenerative disease that occurs due to cellular autophagy deficiency and the accumulation of alpha-synuclein in the dopaminergic neurons of the substantia nigra pars compacta (snc) of the brainstem. 2019-05-23 2023-08-13 rat
Han Wool Kim, Hyun-Seob Lee, Jun Mo Kang, Sang-Hun Bae, Chul Kim, Sang-Hun Lee, Johannes Schwarz, Gi Jin Kim, Jin-Su Kim, Dong Hyun Cha, Joopyung Kim, Sung Woon Chang, Tae Hee Lee, Jisook Moo. Dual Effects of Human Placenta-Derived Neural Cells on Neuroprotection and the Inhibition of Neuroinflammation in a Rodent Model of Parkinson's Disease. Cell transplantation. vol 27. issue 5. 2019-05-17. PMID:29871515. parkinson's disease (pd) is the second most common age-related neurodegenerative disease in the elderly and the patients suffer from uncontrolled movement disorders due to loss of dopaminergic (da) neurons on substantia nigra pars compacta (snpc). 2019-05-17 2023-08-13 human
Hector Rosas-Hernandez, Srinivasulu Chigurupati, James Raymick, Bonnie Robinson, Elvis Cuevas, Joseph Hanig, Sumit Sarka. Identification of altered microRNAs in serum of a mouse model of Parkinson's disease. Neuroscience letters. vol 687. 2019-03-11. PMID:30025832. parkinson's disease (pd) is the second most prevalent neurodegenerative disease, whose hallmark is the loss of dopamine terminals in the substantia nigra pars compacta (snpc). 2019-03-11 2023-08-13 mouse
Kunhua Hu, Qiaoying Huang, Chong Liu, Yongyi Li, Yueyue Liu, Hao Wang, Mingtao Li, Shanshan M. c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease. Neuroscience. vol 399. 2019-03-11. PMID:30590105. parkinson's disease (pd) is a common neurodegenerative disease that is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2019-03-11 2023-08-13 mouse
E K El-Sayed, Aae Ahmed, Em El Morsy, S Nofa. Neuroprotective effect of agmatine (decarboxylated l-arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson's disease. Human & experimental toxicology. vol 38. issue 2. 2019-03-07. PMID:30001633. parkinson's disease (pd) is the second most common age-related neurodegenerative disease after alzheimer's disease, characterized by loss of dopaminergic neurons in substantia nigra pars compacta, accompanied by motor and nonmotor symptoms. 2019-03-07 2023-08-13 rat
Roberta de Paula Martins, Viviane Glaser, Aderbal S Aguiar, Priscila Maximiliano de Paula Ferreira, Karina Ghisoni, Débora da Luz Scheffer, Laurence Lanfumey, Rita Raisman-Vozari, Olga Corti, Ana Lucia De Paul, Rodrigo Augusto da Silva, Alexandra Latin. De novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin Cell biology international. vol 42. issue 6. 2018-10-02. PMID:29624777. de novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin parkinson's disease (pd), the second-most prevalent neurodegenerative disease, is primarily characterized by neurodegeneration in the substantia nigra pars compacta, resulting in motor impairment. 2018-10-02 2023-08-13 Not clear
Ming Hu, Fangming Li, Weidong Wan. Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway. Drug design, development and therapy. vol 12. 2018-09-17. PMID:29588573. parkinson's disease (pd) is a progressive neurodegenerative disease which is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2018-09-17 2023-08-13 Not clear
Natalia Areiza Mazo, Valentina Echeverria, Ricardo Cabezas, Marco Avila-Rodriguez, Vadim V Tarasov, Nagendra S Yarla, Gjumrakch Aliev, George E Barret. Medicinal Plants as Protective Strategies Against Parkinson's Disease. Current pharmaceutical design. vol 23. issue 28. 2018-07-05. PMID:28302024. parkinson's disease is a neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra pars compacta region. 2018-07-05 2023-08-13 Not clear
Itzia Jimenez-Ferrer, Michael Jewett, Ashmita Tontanahal, Marina Romero-Ramos, Maria Swanber. Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration. Neurobiology of disease. vol 106. 2018-05-15. PMID:28736195. parkinson's disease (pd) is a complex and heterogeneous neurodegenerative disease characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta and pathological intracellular accumulation of alpha-synuclein (α-syn). 2018-05-15 2023-08-13 human
Kamal Awad, Abdelrahman Ibrahim Abushouk, Ahmed Helal AbdelKarim, Maged Mohammed, Ahmed Negida, Ali S Shalas. Bee venom for the treatment of Parkinson's disease: How far is it possible? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 91. 2018-03-26. PMID:28477460. parkinson's disease (pd) is the second most common neurodegenerative disease, characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta leading to depletion of striatal dopamine and motor symptoms as bradykinesia, resting tremors, rigidity, and postural instability. 2018-03-26 2023-08-13 bee
Siamak Afshin-Majd, Keyhan Bashiri, Zahra Kiasalari, Tourandokht Baluchnejadmojarad, Reza Sedaghat, Mehrdad Roghan. Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 89. 2018-02-27. PMID:28199883. parkinson's disease (pd) is a movement disorder and the second most common neurodegenerative disease worldwide in which nigrostriatal dopaminergic neurons within substantia nigra pars compacta (snc) are lost, with clinical motor and non-motor symptoms including bradykinesia, resting tremor, rigidity, stooping posture and cognitive deficits. 2018-02-27 2023-08-13 rat
Joseph R Phillips, Abeer M Eissa, Doaa H Hewedi, Marjan Jahanshahi, Mohamed El-Gamal, Szabolcs Keri, Ahmed A Moustaf. Neural substrates and potential treatments for levodopa-induced dyskinesias in Parkinson's disease. Reviews in the neurosciences. vol 27. issue 7. 2018-01-02. PMID:27362959. pd is a neurodegenerative disease, with dopaminergic neuronal loss occurring in the substantia nigra pars compacta, thus disrupting basal ganglia functions. 2018-01-02 2023-08-13 Not clear