| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaedeok Kim, Nayoung Lee, Sang Bum Suh, Sooyeon Jang, Saeha Kim, Dong-Gyu Kim, Jong Kook Park, Keun-Wook Lee, Soo Young Choi, Chan Hee Le. Metformin ameliorates olanzapine-induced disturbances in POMC neuron number, axonal projection, and hypothalamic leptin resistance. BMB reports. 2022-06-02. PMID:35651327. |
while atypical antipsychotics such as aripiprazole are not associated with obesity and diabetes, olanzapine is still widely used based on the anticipation that it is more effective in treating severe schizophrenia than aripiprazole, despite its metabolic side effects. |
2022-06-02 |
2023-08-13 |
mouse |
| Magda Kondej, Tomasz M Wróbel, Katarzyna M Targowska-Duda, Antón Leandro Martínez, Oliwia Koszła, Piotr Stępnicki, Agata Zięba, Alba Paz, Olga Wronikowska-Denysiuk, Maria I Loza, Marián Castro, Agnieszka Anna Kaczo. Multi-target derivatives of D2AAK1 as potential antipsychotics - the effect of the substitution in the indole moiety. ChemMedChem. 2022-05-24. PMID:35610178. |
schizophrenia is a complex disease which is best treated with multi-target drugs, such as atypical antipsychotics. |
2022-05-24 |
2023-08-13 |
mouse |
| Aditi Kadakia, Brenna Brady, Carole Dembek, Rhys Williams, Justine Ken. The Incidence and Economic Burden of Extrapyramidal Symptoms in Patients with Schizophrenia Initiating Atypical Antipsychotics in a Commercially Insured Population. CNS spectrums. vol 27. issue 2. 2022-04-28. PMID:35477614. |
the incidence and economic burden of extrapyramidal symptoms in patients with schizophrenia initiating atypical antipsychotics in a commercially insured population. |
2022-04-28 |
2023-08-13 |
Not clear |
| M A Lech, K Kaminska, A Wasik, E Lorenc-Koci, Z Rogo. Repeated co-treatment with mirtazapine and aripiprazole reversed the schizophrenia-like behaviors and increased the brain-derived neurotrophic factor mRNA expression in the adult Sprague-Dawley rats exposed to glutathione deficit during early postnatal brain development. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 72. issue 5. 2022-02-14. PMID:35158332. |
moreover, some studies have suggested that antidepressants are able to increase the activity of atypical antipsychotics which may efficiently improve the treatment of negative and some cognitive symptoms of schizophrenia. |
2022-02-14 |
2023-08-13 |
rat |
| Yingchan Wang, Yuchao Jiang, Dengtang Liu, Jianye Zhang, Dezhong Yao, Cheng Luo, Jijun Wan. Atypical Antipsychotics Mediate Dynamics of Intrinsic Brain Activity in Early-Stage Schizophrenia? A Preliminary Study. Psychiatry investigation. vol 18. issue 12. 2021-12-30. PMID:34965706. |
atypical antipsychotics mediate dynamics of intrinsic brain activity in early-stage schizophrenia? |
2021-12-30 |
2023-08-13 |
Not clear |
| Yingchan Wang, Yuchao Jiang, Dengtang Liu, Jianye Zhang, Dezhong Yao, Cheng Luo, Jijun Wan. Atypical Antipsychotics Mediate Dynamics of Intrinsic Brain Activity in Early-Stage Schizophrenia? A Preliminary Study. Psychiatry investigation. vol 18. issue 12. 2021-12-30. PMID:34965706. |
abnormalities of static brain activity have been reported in schizophrenia, but it remains to be clarified the temporal variability of intrinsic brain activities in schizophrenia and how atypical antipsychotics affect it. |
2021-12-30 |
2023-08-13 |
Not clear |
| Luyao He, Yimin Yu, Lei Zhang, Shen He, Wenjuan Yu, Lujin Li, Jingjing Huang, Huafang L. A Real-World Study of Risk Factors for QTc Prolongation in Schizophrenia Patients Receiving Atypical Antipsychotics. Journal of clinical psychopharmacology. vol 42. issue 1. 2021-12-20. PMID:34928562. |
a real-world study of risk factors for qtc prolongation in schizophrenia patients receiving atypical antipsychotics. |
2021-12-20 |
2023-08-13 |
Not clear |
| Pan Yan, Bing Gao, Shuqi Wang, Shengdong Wang, Jing Li, Mingfen Son. Association of 5-HTR2A T102C and A-1438G polymorphisms with clinical response to atypical antipsychotic treatment in schizophrenia: a meta-analysis. Neuroscience letters. 2021-12-17. PMID:34919991. |
associations of serotonin 2a receptor (5-htr2a) gene polymorphisms with clinical response to atypical antipsychotics (aaps) treatment in schizophrenia (scz) were inconsistent. |
2021-12-17 |
2023-08-13 |
Not clear |
| Enrico Capuzzi, Alessandro Ceresa, Alice Caldiroli, Cecilia M Esposito, Paolo Ossola, Massimiliano Buol. The Relation between the Plasma Concentrations of Long-Acting Atypical Antipsychotics and Clinical Effectiveness in Patients Affected by Schizophrenia or Schizoaffective Disorder: A Comprehensive Overview. Current pharmaceutical design. vol 27. issue 39. 2021-12-07. PMID:34459376. |
the relation between the plasma concentrations of long-acting atypical antipsychotics and clinical effectiveness in patients affected by schizophrenia or schizoaffective disorder: a comprehensive overview. |
2021-12-07 |
2023-08-13 |
Not clear |
| Chih-Sung Liang, Tung-Ping Su, Ming-Hsien Hsieh, Chau-Shoun Lee, Joseph Kuo, Nan-Ying Chiu, Po-See Chen, Yung-Chieh Yen, Ya-Mei Ba. Taiwan Expert Consensus Recommendations for Switching to Aripiprazole Long-Acting Once-Monthly in Patients with Schizophrenia. Journal of personalized medicine. vol 11. issue 11. 2021-11-30. PMID:34834550. |
the panel developed nine consensus statements of switching to aom for both acute and stable schizophrenia patients receiving oral or long-acting injectable atypical antipsychotics. |
2021-11-30 |
2023-08-13 |
Not clear |
| b' Marta A Lech, Kinga Kami\\xc5\\x84ska, Monika Le\\xc5\\x9bkiewicz, El\\xc5\\xbcbieta Lorenc-Koci, Zofia Rog\\xc3\\xb3\\xc5\\xb. Impact of repeated co-treatment with escitalopram and aripiprazole on the schizophrenia-like behaviors and BDNF mRNA expression in the adult Sprague-Dawley rats exposed to glutathione deficit during early postnatal development of the brain. Pharmacological reports : PR. vol 73. issue 6. 2021-11-25. PMID:34398437.' |
moreover, some studies have suggested that antidepressants are able to increase the activity of atypical antipsychotics which may efficiently improve the treatment of negative and cognitive symptoms of schizophrenia. |
2021-11-25 |
2023-08-13 |
rat |
| Mina Y George, Esther T Menze, Ahmed Esmat, Mariane G Tadros, Ebtehal El-Demerdas. Naringin treatment improved main clozapine-induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis. Drug development research. vol 82. issue 7. 2021-11-15. PMID:33537987. |
among them, clozapine is one of the atypical antipsychotics prescribed in schizophrenia wing to its blocking effect on dopamine (d2) and serotonin (5-ht |
2021-11-15 |
2023-08-13 |
rat |
| Leslie Citrome, Jan Volavk. Specific Anti-hostility Effects of Atypical Antipsychotics in Persons with Schizophrenia: From Clozapine to Cariprazine. Harvard review of psychiatry. vol 29. issue 1. 2021-10-25. PMID:33417374. |
specific anti-hostility effects of atypical antipsychotics in persons with schizophrenia: from clozapine to cariprazine. |
2021-10-25 |
2023-08-13 |
Not clear |
| Susan M Shortreed, Erica E M Moodi. Estimating the optimal dynamic antipsychotic treatment regime: Evidence from the sequential multiple assignment randomized CATIE Schizophrenia Study. Journal of the Royal Statistical Society. Series C, Applied statistics. vol 61. issue 4. 2021-10-21. PMID:23087488. |
the clinical antipsychotic trials in intervention effectiveness (catie) schizophrenia study is a sequential multiple assignment randomized trial comparing the typical antipsychotic medication, perphenazine, to several newer atypical antipsychotics. |
2021-10-21 |
2023-08-12 |
Not clear |
| Jessica Panish, Sudeep Karve, Sean D Candrilli, Riad Diran. Association between adherence to and persistence with atypical antipsychotics and psychiatric relapse among US Medicaid-enrolled patients with schizophrenia. Journal of pharmaceutical health services research : an official journal of the Royal Pharmaceutical Society of Great Britain. vol 4. issue 1. 2021-10-21. PMID:23486693. |
association between adherence to and persistence with atypical antipsychotics and psychiatric relapse among us medicaid-enrolled patients with schizophrenia. |
2021-10-21 |
2023-08-12 |
Not clear |
| b' Marta Hereta, Kinga Kami\\xc5\\x84ska, Magdalena Bia\\xc5\\x82o\\xc5\\x84, Agnieszka W\\xc4\\x85sik, El\\xc5\\xbcbieta Lorenc-Koci, Zofia Rog\\xc3\\xb3\\xc5\\xb. Effect of combined treatment with aripiprazole and antidepressants on the MK-801-induced deficits in recognition memory in novel recognition test and on the release of monoamines in the rat frontal cortex. Behavioural brain research. vol 393. 2021-10-04. PMID:32535184.' |
according to preclinical and clinical studies, the antidepressant-induced increase in the activity of atypical antipsychotics may efficiently improve the treatment of negative and some cognitive symptoms of schizophrenia. |
2021-10-04 |
2023-08-13 |
rat |
| Shamir N Kalaria, Tiffany R Farchione, Ramana Uppoor, Mehul Mehta, Yaning Wang, Hao Zh. Extrapolation of Efficacy and Dose Selection in Pediatrics: A Case Example of Atypical Antipsychotics in Adolescents With Schizophrenia and Bipolar I Disorder. Journal of clinical pharmacology. vol 61 Suppl 1. 2021-09-23. PMID:34185904. |
extrapolation of efficacy and dose selection in pediatrics: a case example of atypical antipsychotics in adolescents with schizophrenia and bipolar i disorder. |
2021-09-23 |
2023-08-13 |
Not clear |
| Shalu Singh, Alka Bali, Tania Peshi. Synthesis and Evaluation of Aryl Substituted Propyl Piperazines for Potential Atypical Antipsychotic Activity. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 17. issue 5. 2021-08-16. PMID:31642788. |
atypical antipsychotics are the agents which do not give rise to significant extrapyramidal side effects and are more effective against negative symptoms of schizophrenia. |
2021-08-16 |
2023-08-13 |
Not clear |
| Robert Pudlo, Magdalena Piegza, Urszula Michalik-Marcinkowska, Gniewko Więckiewicz, Izabela Jaworsk. Long-term psychoeducation in limiting body mass gain in patients treated with atypical antipsychotics. Psychiatria polska. vol 55. issue 2. 2021-08-08. PMID:34365479. |
the aim of the study was to assess efficacy of psychoeducation in limiting body mass gain in patients with schizophrenia undergoing atypical antipsychotics monotherapy treatment. |
2021-08-08 |
2023-08-13 |
Not clear |
| Izabela Fulone, Marcus Tolentino Silva, Luciane Cruz Lope. Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil. BMC psychiatry. vol 21. issue 1. 2021-08-06. PMID:34187418. |
gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in brazil. |
2021-08-06 |
2023-08-13 |
Not clear |