| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu Yu, Zuohui Zhang, Hao Chen, Miao Wang, Wenqi Mao, Jinxia Hu, Dandan Zuo, Bingchen Lv, Weifeng Wu, Suhua Qi, Guiyun Cu. Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke. Bioengineering & translational medicine. vol 8. issue 6. 2023-12-01. PMID:38023701. |
remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating hgf after acute ischemia stroke. |
2023-11-29 |
2023-12-07 |
mouse |
| Weizhuo Lu, Zhiwu Chen, Jiyue We. Flavonoids and ischemic stroke-induced neuroinflammation: Focus on the glial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-11-28. PMID:38016362. |
after stroke onset, microglia, astrocytes and the infiltrating immune cells contribute to a complicated neuroinflammation cascade and play the complicated roles in the pathophysiological variations of ischemic stroke. |
2023-11-28 |
2023-12-07 |
Not clear |
| Nikolett Lénárt, Csaba Cserép, Eszter Császár, Balázs Pósfai, Ádám Déne. Microglia-neuron-vascular interactions in ischemia. Glia. 2023-11-15. PMID:37964690. |
while the contribution of non-neuronal cells to stroke pathophysiology is increasingly recognized, recent data show that microglia, the main immune cells of the central nervous system parenchyma, play previously unrecognized roles in basic physiological processes beyond their inflammatory functions, which markedly change during ischemic conditions. |
2023-11-15 |
2023-11-20 |
Not clear |
| Miguel M Lino, Tiago Rondão, Arnab Banerjee, Inês Aires, Magda Rodrigues, Tiago Reis, António Santinha, Dominique Fernandes, Débora Serrenho, Tomás Sobrino, João Sargento-Freitas, Frederico C Pereira, Ana Luísa Carvalho, Lino Ferreir. Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. Nanoscale. 2023-11-07. PMID:37933179. |
small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. |
2023-11-07 |
2023-11-08 |
mouse |
| Kimberly Prescott, Alexandra E Münch, Evan Brahms, Maya M Weigel, Kenya Inoue, Marion S Buckwalter, Shane A Liddelow, Todd C Peterso. Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke. bioRxiv : the preprint server for biology. 2023-10-31. PMID:37905154. |
microglia and astrocytes play an important role in the neuroinflammatory response and contribute to both the destruction of neighboring tissue as well as the resolution of inflammation following stroke. |
2023-10-31 |
2023-11-08 |
Not clear |
| Fatemehsadat Seyedaghamiri, Mohammad Hossein Geranmayeh, Tahereh Ghadiri, Abbas Ebrahimi-Kalan, Leila Hossein. A new insight into the role of pericytes in ischemic stroke. Acta neurologica Belgica. 2023-10-07. PMID:37805645. |
microglia regulate immunity and inflammatory response after stroke. |
2023-10-07 |
2023-10-15 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
changes in microglia during drug treatment of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
microglia play a complex role in the process of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
therefore, we talk about the pathophysiological mechanisms of stroke and elaborate on the microglia signaling pathways of drug action in stroke models and how these drugs play a role in stroke treatment in this review. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
understanding how drugs modulate proinflammatory and anti-inflammatory responses of microglia may be critical to implementing therapeutic strategies using immune interventions in stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| S J Myers, Agapova, S V Patel, S H Hayes, L A Sposato, B L Allman, S N Whitehea. Acute minocycline treatment inhibits microglia activation, reduces infarct volume, and has domain-specific effects on post-ischemic stroke cognition in rats. Behavioural brain research. 2023-09-24. PMID:37742808. |
acute minocycline treatment inhibits microglia activation, reduces infarct volume, and has domain-specific effects on post-ischemic stroke cognition in rats. |
2023-09-24 |
2023-10-07 |
rat |
| George Fadoul, Milos Ikonomovic, Feng Zhang, Tuo Yan. The cell-specific roles of Nrf2 in acute and chronic phases of ischemic stroke. CNS neuroscience & therapeutics. 2023-09-16. PMID:37715557. |
in this review, we comprehensively summarize the protective effects of nrf2 in experimental ischemic stroke, emphasizing the role of nrf2 in different cell types including neurons, astrocytes, oligodendrocytes, microglia, and endothelial cells during acute and chronic phases of stroke and providing insights on the neuroprotective role of nrf2 on each cell type throughout the long term of stroke care. |
2023-09-16 |
2023-10-07 |
Not clear |
| Matteo Haupt, Stefan T Gerner, Hagen B Huttner, Thorsten R Doeppne. Preconditioning Concepts for the Therapeutic Use of Extracellular Vesicles Against Stroke. Stem cells translational medicine. 2023-09-11. PMID:37696005. |
various preclinical stroke models have demonstrated the neuroprotective effects of extracellular vesicles (evs) obtained from several types of cells, including neurons, astrocytes, microglia, neuronal progenitor cells, bone marrow stem cells, and mesenchymal stem cells. |
2023-09-11 |
2023-10-07 |
Not clear |
| Chikage Kijima, Toshiki Inaba, Kenichiro Hira, Nobukazu Miyamoto, Kazuo Yamashiro, Takao Urabe, Nobutaka Hattori, Yuji Uen. Astrocytic Extracellular Vesicles Regulated by Microglial Inflammatory Responses Improve Stroke Recovery. Molecular neurobiology. 2023-09-07. PMID:37676390. |
we investigated whether astrocytic extracellular vesicles (aevs) regulated by microglia modulate glial scars and improve stroke recovery. |
2023-09-07 |
2023-10-07 |
Not clear |
| Confidence Dordoe, Wenting Huang, Canol Bwalya, Xue Wang, Bixin Shen, Hao Wang, Jing Wang, Shasha Ye, Peng Wang, Bao Xiaoyan, Xiaokun Li, Li Li. The role of microglial activation on ischemic stroke: Modulation by fibroblast growth factors. Cytokine & growth factor reviews. 2023-08-12. PMID:37573252. |
in this review, we outline current evidence of microglia activation in experimental models of stroke focusing on its ability to exacerbate damage or repair tissue. |
2023-08-12 |
2023-08-16 |
Not clear |
| Hui-Xing Wei, Yun-Ni Guan, Ping-Ping Chen, Zhao-Zeng Rao, Jin-Shan Yan. Upregulation of EphA4 deteriorate brain damage by shifting microglia M1-polarization via NF-κB signaling after focal cerebral ischemia in rats. Heliyon. vol 9. issue 7. 2023-07-31. PMID:37519758. |
promoting microglia phenotype shift from deleterious m1 phenotype to neuroprotective m2 phenotype will be promising in stroke treatment. |
2023-07-31 |
2023-08-14 |
human |
| Yao Ya. NR4A1 destabilizes TNF mRNA in microglia and modulates stroke outcomes. PLoS biology. vol 21. issue 7. 2023-07-26. PMID:37490433. |
nr4a1 destabilizes tnf mrna in microglia and modulates stroke outcomes. |
2023-07-26 |
2023-08-14 |
Not clear |
| Yao Ya. NR4A1 destabilizes TNF mRNA in microglia and modulates stroke outcomes. PLoS biology. vol 21. issue 7. 2023-07-26. PMID:37490433. |
microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. |
2023-07-26 |
2023-08-14 |
Not clear |
| Pinyi Liu, Yan Chen, Zhi Zhang, Zengqiang Yuan, Jian-Guang Sun, Shengnan Xia, Xiang Cao, Jian Chen, Cun-Jin Zhang, Yanting Chen, Hui Zhan, Yuexinzi Jin, Xinyu Bao, Yue Gu, Meijuan Zhang, Yun X. Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization. PLoS biology. vol 21. issue 7. 2023-07-25. PMID:37486903. |
thus, our study illustrates a novel mechanism that nr4a1 posttranscriptionally regulates tnf expression in microglia and determines stroke outcomes. |
2023-07-25 |
2023-08-14 |
mouse |
| Jerry Flores, Jiping Tan. Role of N-formyl peptide receptor 2 in germinal matrix hemorrhage: an intrinsic review of a hematoma resolving pathway. Neural regeneration research. vol 19. issue 2. 2023-07-25. PMID:37488889. |
various articles have demonstrated the beneficial effects of stimulating the polarization of microglia cells into the m2 phenotype, as it has been suggested that they play an essential role in the rapid phagocytosis of the blood clot after hemorrhagic models of stroke. |
2023-07-25 |
2023-08-14 |
Not clear |