| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting-Ting Zhan, Zhi-Yu Dong, Li-Sha Yi, Yan Zhang, Hui-Hui Sun, Hai-Qin Zhang, Jun-Wen Wang, Ying Chen, Ying Huang, Shu-Chang X. Tandospirone prevents stress-induced anxiety-like behavior and visceral hypersensitivity by suppressing theta oscillation enhancement Frontiers in cellular neuroscience. vol 16. 2022-09-08. PMID:36072567. |
in this study, using a visceral hypersensitivity rat model induced by chronic water avoidance stress to mimic the symptoms of irritable bowel syndrome, we found that tandospirone relieved anxiety-like behavior and visceral hypersensitivity induced by stress. |
2022-09-08 |
2023-08-14 |
rat |
| D.J. Sanger, D. Joly, M. LePicho. Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. Behavioural pharmacology. vol 1. issue 2. 2019-11-20. PMID:11175398. |
buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. |
2019-11-20 |
2023-08-12 |
rat |
| D.J. Sanger, D. Joly, M. LePicho. Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. Behavioural pharmacology. vol 1. issue 2. 2019-11-20. PMID:11175398. |
buspirone has been reported to disrupt active avoidance responding without interfering with the ability to escape the aversive stimuli, an effect usually associated with antipsychotic drugs. |
2019-11-20 |
2023-08-12 |
rat |
| D.J. Sanger, D. Joly, M. LePicho. Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. Behavioural pharmacology. vol 1. issue 2. 2019-11-20. PMID:11175398. |
in the present study, buspirone, gepirone and ipsapirone produced dose-related decreases in one-way, active avoidance responding of rats. |
2019-11-20 |
2023-08-12 |
rat |
| D.J. Sanger, D. Joly, M. LePicho. Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. Behavioural pharmacology. vol 1. issue 2. 2019-11-20. PMID:11175398. |
in a second experiment, buspirone, gepirone and ipsapirone disrupted the performance of a passive avoidance response. |
2019-11-20 |
2023-08-12 |
rat |
| D.J. Sanger, D. Joly, M. LePicho. Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats. Behavioural pharmacology. vol 1. issue 2. 2019-11-20. PMID:11175398. |
these disruptions of the performance of both active and passive avoidance indicate a unique pharmacological profile for buspirone and similar drugs. |
2019-11-20 |
2023-08-12 |
rat |
| D.J. Sanger, D. Jol. Performance of a passive avoidance response is disrupted by compounds acting at 5HT(1A) receptors. Behavioural pharmacology. vol 1. issue 3. 2019-11-20. PMID:11224034. |
in a previous study it was found that the anxiolytic drug buspirone and the related compounds gepirone and ipsapirone disrupted the performance of a passive avoidance response by rats. |
2019-11-20 |
2023-08-12 |
rat |
| T. Klin. Effects of 8-OH-DPAT and buspirone in a passive avoidance test and in the elevated plus-maze test in rats. Behavioural pharmacology. vol 2. issue 6. 2019-11-20. PMID:11224090. |
effects of 8-oh-dpat and buspirone in a passive avoidance test and in the elevated plus-maze test in rats. |
2019-11-20 |
2023-08-12 |
rat |
| T. Klin. Effects of 8-OH-DPAT and buspirone in a passive avoidance test and in the elevated plus-maze test in rats. Behavioural pharmacology. vol 2. issue 6. 2019-11-20. PMID:11224090. |
the effects of the two 5-ht(1a) agonists 8-oh-dpat and buspirone were studied in a passive avoidance test and in an elevated plus-maze test. |
2019-11-20 |
2023-08-12 |
rat |
| T. Klin. Effects of 8-OH-DPAT and buspirone in a passive avoidance test and in the elevated plus-maze test in rats. Behavioural pharmacology. vol 2. issue 6. 2019-11-20. PMID:11224090. |
in the passive avoidance test 8-oh-dpat and buspirone, as well as diazepam and chlordiazepoxide, were effective, while, in the elevated plus-maze test, the two benzodiazepines were active whereas buspirone and 8-oh-dpat were not. |
2019-11-20 |
2023-08-12 |
rat |
| M. Galizio, K.L. Hale, M.O. Liborio, M. Mille. Variable-ratio schedules of timeout from avoidance: effects of anxiolytic drugs. Behavioural pharmacology. vol 4. issue 5. 2019-11-20. PMID:11224215. |
buspirone decreased responding across all effective doses, but 8-oh-dpat increased responding on both the timeout and avoidance levers, with greater increases noted in responding maintained by timeout. |
2019-11-20 |
2023-08-12 |
rat |
| Hiroyuki Arakaw. Analysis of Social Process in Two Inbred Strains of Male Mice: A Predominance of Contact-Based Investigation in BALB/c Mice. Neuroscience. vol 369. 2019-02-18. PMID:29138108. |
this anogenital aversion disappeared when the stranger mice received a buspirone injection that reduced anxiety or when familiar cagemates were exposed. |
2019-02-18 |
2023-08-13 |
mouse |
| Nausheen Alam, Rahila Najam, Saira Saeed Kha. Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration. Pakistan journal of pharmaceutical sciences. vol 28. issue 5. 2015-12-15. PMID:26408868. |
cognitive effects were compared by using water maze and passive avoidance test weekly after long-term administration of methylphenidate, buspirone and their co-administration. |
2015-12-15 |
2023-08-13 |
rat |
| Kerstin E A Wernecke, Markus Fend. The olfactory hole-board test in rats: a new paradigm to study aversion and preferences to odors. Frontiers in behavioral neuroscience. vol 9. 2015-09-18. PMID:26379516. |
to test whether anxiolytic treatment specifically modulates the avoidance of carnivore urine holes, we treated rats with buspirone. |
2015-09-18 |
2023-08-13 |
rat |
| Kerstin E A Wernecke, Markus Fend. The olfactory hole-board test in rats: a new paradigm to study aversion and preferences to odors. Frontiers in behavioral neuroscience. vol 9. 2015-09-18. PMID:26379516. |
buspirone treatment completely abolished the avoidance of carnivore urine holes. |
2015-09-18 |
2023-08-13 |
rat |
| Adam Hamed, Tomasz Jaroszewski, Piotr Maciejak, Janusz Szyndler, Małgorzata Lehner, Ita Kamecka, Mieszko Olczak, Urszula Kuzinska, Ewa Taracha, Adam Płaźni. The effects of buspirone and diazepam on aversive context- and social isolation-induced ultrasonic vocalisation. Physiology & behavior. vol 98. issue 4. 2009-12-09. PMID:19660481. |
the effects of buspirone and diazepam on aversive context- and social isolation-induced ultrasonic vocalisation. |
2009-12-09 |
2023-08-12 |
rat |
| Marilia Barros, Rafael Souto Maior, Joseph P Huston, Carlos Toma. Predatory stress as an experimental strategy to measure fear and anxiety-related behaviors in non-human primates. Reviews in the neurosciences. vol 19. issue 2-3. 2008-11-05. PMID:18751522. |
pharmacological validating studies with diazepam and buspirone induced a significant dose-dependent reversal of the fear-induced proximic avoidance and scratching/scent-marking behaviors, while exploration (smell/lick the maze, leg stand) was found to increase. |
2008-11-05 |
2023-08-12 |
human |
| Aaron Ettenberg, Rick E Bernard. Anxiolytic-like actions of buspirone in a runway model of intravenous cocaine self-administration. Pharmacology, biochemistry, and behavior. vol 85. issue 2. 2007-02-20. PMID:17064759. |
since most animal tests of conflict/anxiety employ the administration of foot-shock - a relatively strong aversive stimulus - it was of interest to determine whether buspirone would alter the more subtle approach-avoidance conflict observed in well-trained animals running a straight alley for single daily injections of 1.0 mg/kg iv cocaine. |
2007-02-20 |
2023-08-12 |
human |
| Cs Leveleki, N Sziray, G Levay, B Barsvári, K Soproni, E Mikics, J Halle. Pharmacological evaluation of the stress-induced social avoidance model of anxiety. Brain research bulletin. vol 69. issue 2. 2006-06-01. PMID:16533664. |
low doses of chlordiazepoxide (0.5, 1 mg/kg), diazepam (0.5, 1, 5 mg/kg), buspirone (0.3, 1 mg/kg), and fluoxetine (1, 3, 5 mg/kg) abolished this effect, whereas the anxiogenic compound m-chlorophenylpiperazine (0.5-3 mg/kg) induced social avoidance in unshocked rats. |
2006-06-01 |
2023-08-12 |
rat |
| J M Zanoveli, R L Nogueira, H Zangross. Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety. Behavioural pharmacology. vol 16. issue 7. 2005-11-30. PMID:16170231. |
chronic buspirone did not change the effect of 8-oh-dpat and doi on inhibitory avoidance and escape. |
2005-11-30 |
2023-08-12 |
rat |