| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G N Ervin, R B Carter, E L Webster, S I Moore, B R Coope. Evidence that taste aversion learning induced by l-5-hydroxytryptophan is mediated peripherally. Pharmacology, biochemistry, and behavior. vol 20. issue 5. 1984-08-07. PMID:6610880. |
these results indicate that l-5-htp-induced taste aversion is correlated with peripheral, but not central, elevation of 5-ht. |
1984-08-07 |
2023-08-12 |
rat |
| S L Shelekhov, A V Val'dma. [Neurochemical analysis of the mechanism of action of serotoninergic substances on avoidance behavior in situations of acute stress]. Biulleten' eksperimental'noi biologii i meditsiny. vol 97. issue 4. 1984-07-13. PMID:6232963. |
the optimizing effect of 5-ht on the avoidance behavior was demonstrated to be a consequence of serotonin synthesis activation and its release with activation of postsynaptic 5-ht-1-receptors. |
1984-07-13 |
2023-08-12 |
Not clear |
| S L Shelekhov, A V Val'dma. [Neurochemical analysis of the mechanism of action of serotoninergic substances on avoidance behavior in situations of acute stress]. Biulleten' eksperimental'noi biologii i meditsiny. vol 97. issue 4. 1984-07-13. PMID:6232963. |
the positive effect on the avoidance behavior under stress occurs as a result of exposures that activate the synthesis and release of 5-ht as well as of activation of postsynaptic 5-ht-1 receptors. |
1984-07-13 |
2023-08-12 |
Not clear |
| A Płaźnik, W Danysz, W Kostowsk. Some behavioral effects of microinjections of noradrenaline and serotonin into the hippocampus of the rat. Physiology & behavior. vol 31. issue 5. 1984-03-12. PMID:6320239. |
5ht injections inhibited the rats exploratory behavior in the open field test, attenuated the retention of a passive avoidance reaction and increased suppressant effects of shock in the conflict test. |
1984-03-12 |
2023-08-12 |
rat |
| P Driscoll, J Dedek, J R Martin, B Zivkovi. Two-way avoidance and acute shock stress induced alterations of regional noradrenergic, dopaminergic and serotonergic activity in Roman high- and low-avoidance rats. Life sciences. vol 33. issue 17. 1983-12-17. PMID:6195502. |
these results indicated, pending further studies regarding, for example, possible genetic differences in tryptophan uptake and utilization, that 5-ht probably plays at least a modulatory role in the reaction to stress, and in avoidance behavior. |
1983-12-17 |
2023-08-12 |
human |
| P Cazala, A M Garrigue. Effects of apomorphine, clonidine or 5-methoxy-NN-dimethyltryptamine on approach and escape components of lateral hypothalamic and mesencephalic central gray stimulation in two inbred strains of mice. Pharmacology, biochemistry, and behavior. vol 18. issue 1. 1983-04-21. PMID:6338533. |
these results suggest that the neurochemical regulation of escape reactions respectively generated by lh or cg activation is partially different: dopamine seems to be involved only in cg aversion, whereas serotonin (5-ht) modulates both lh and cg escape reactions. |
1983-04-21 |
2023-08-12 |
mouse |
| G Bamme. Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: a review and some new results. Neuroscience and biobehavioral reviews. vol 6. issue 3. 1983-02-14. PMID:6129605. |
the roles of acetylcholine (ach), noradrenaline (na), dopamine (da) and serotonin (5-ht) in passive avoidance responding are examined by reviewing previous studies of the effects on this task of drugs which alter the functioning of these neurotransmitter systems and also by presenting the results of a new study. |
1983-02-14 |
2023-08-12 |
Not clear |
| J F McElroy, A F Du Pont, R S Feldma. The effects of fenfluramine and fluoxetine on the acquisition of the conditioned avoidance response in rats. Psychopharmacology. vol 77. issue 4. 1982-12-16. PMID:6813897. |
when the drug-test interval was 1 h, a time when both drugs are presumably potentiating 5-ht activity, avoidance acquisition and intertrial responding were impaired. |
1982-12-16 |
2023-08-12 |
rat |
| J F McElroy, A F Du Pont, R S Feldma. The effects of fenfluramine and fluoxetine on the acquisition of the conditioned avoidance response in rats. Psychopharmacology. vol 77. issue 4. 1982-12-16. PMID:6813897. |
when testing occurred 8 h after drug treatment, a time when 5-ht level are unaltered by fxt and are maximally reduced by fen, these drugs had no effect on avoidance acquisition, but fen produced an increase in intertrial responses whereas fxt did not. |
1982-12-16 |
2023-08-12 |
rat |
| S O Ogre. Forebrain serotonin and avoidance learning: behavioural and biochemical studies on the acute effect of p-chloroamphetamine on one-way active avoidance learning in the male rat. Pharmacology, biochemistry, and behavior. vol 16. issue 6. 1982-10-12. PMID:7111347. |
pretreatment with the selective serotonin (5-ht) uptake inhibitors fluoxetine and zimelidine, but not the noradrenaline (na) uptake inhibitor desipramine, resulted in a blockade of the avoidance deficit. |
1982-10-12 |
2023-08-12 |
rat |
| S O Ogre. Forebrain serotonin and avoidance learning: behavioural and biochemical studies on the acute effect of p-chloroamphetamine on one-way active avoidance learning in the male rat. Pharmacology, biochemistry, and behavior. vol 16. issue 6. 1982-10-12. PMID:7111347. |
degeneration of brain 5-ht neurons by a high neurotoxic dose of pca (2 x 10 mg/kg ip) 7 days prior to the administration of pca also blocked the avoidance deficit. |
1982-10-12 |
2023-08-12 |
rat |
| T Arche. DSP4 (N-2-chloroethyl-N-ethyl-2-bromobenzylamine), a new noradrenaline neurotoxin, and stimulus conditions affecting acquisition of two-way active avoidance. Journal of comparative and physiological psychology. vol 96. issue 3. 1982-09-24. PMID:7096684. |
it seems unlikely that the small serotonin depletions evidenced here can account for the avoidance deficits. |
1982-09-24 |
2023-08-12 |
rat |
| J M Murphy, W J McBride, L Lumeng, T K L. Regional brain levels of monoamines in alcohol-preferring and -nonpreferring lines of rats. Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:6173885. |
regional brain levels of serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), dopamine (da) and norepinephrine (ne) were determined in alcohol-naive rats from lines selectively bred for alcohol preference (p) and alcohol aversion (nonpreference, np). |
1982-04-12 |
2023-08-12 |
rat |
| J D Pollock, N Rowlan. Peripherally administered serotonin decreases food intake in rats. Pharmacology, biochemistry, and behavior. vol 15. issue 2. 1982-02-12. PMID:7312891. |
further, 2 mg/kg serotonin (ed50 on food intake) did not produce a conditioned taste aversion when paired repeatedly with sucrose ingestion. |
1982-02-12 |
2023-08-12 |
rat |
| V M Getsov. [Effect of scopolamine on formation and fixation of temporary connections in rats with altered brain serotonin levels]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 31. issue 4. 1982-01-09. PMID:6458175. |
the influence of scopolamine on elaboration and maintenance of conditioned reflexes of two-way avoidance was studied in rats under conditions of excess and deficit of serotonin in the brain. |
1982-01-09 |
2023-08-12 |
rat |
| J F Deaki. On the neurochemical basis of self-stimulation with midbrain raphe electrode placements. Pharmacology, biochemistry, and behavior. vol 13. issue 4. 1981-01-29. PMID:6449012. |
termination of (escape from) stimulation was not materially affected by catecholamine or 5ht depletion suggesting the aversive component of raphe stimulation may not be mediated by these monoamines. |
1981-01-29 |
2023-08-12 |
rat |
| A Płaznik, W Kostowsk. Effects of p-bromo-methamphetamine (V-111) on conditioned avoidance behavior in rats with lesioned raphe nuclei. Polish journal of pharmacology and pharmacy. vol 31. issue 3. 1980-01-24. PMID:503968. |
effect of treatment with p-bromo-methamphetamine (v-111), the serotonin depleting drug, on two way avoidance conditioning (car) was studied in raphe lesioned male wistar rats. |
1980-01-24 |
2023-08-11 |
rat |
| J F Deakin, S E File, J R Hyde, N K Macleo. Ascending 5-HT pathways and behavioural habituation. Pharmacology, biochemistry, and behavior. vol 10. issue 5. 1979-12-18. PMID:493286. |
rather, 5-ht neurones may be involved in modulation of activity or responsiveness to aversive environments. |
1979-12-18 |
2023-08-11 |
rat |
| C V Vorhee. Facilitation of avoidance acquisition in rats produced by P-chlorophenylalanine or P-chloroamphetamine. Pharmacology, biochemistry, and behavior. vol 10. issue 4. 1979-09-17. PMID:156926. |
the effects of reducing brain serotonin using p-chlorophenylalanine (pcpa) were examined as a follow up to our previous report that reducing serotonin with p-chloroamphetamine (pca) facilitated y-maze avoidance acquisition and reduced open field activity. |
1979-09-17 |
2023-08-11 |
rat |
| C V Vorhee. Facilitation of avoidance acquisition in rats produced by P-chlorophenylalanine or P-chloroamphetamine. Pharmacology, biochemistry, and behavior. vol 10. issue 4. 1979-09-17. PMID:156926. |
the present data, in conjunction with our previous data support the concept that lowered brain serotonin content facilitates avoidance acquisition regardless of the specific method used to reduce serotonin or to assess avoidance acquisition. |
1979-09-17 |
2023-08-11 |
rat |