| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiun Youn, Ilga Misane, Therese M Eriksson, Mark J Millan, Sven Ove Ogren, Matthijs Verhage, Oliver Stied. Bidirectional modulation of classical fear conditioning in mice by 5-HT(1A) receptor ligands with contrasting intrinsic activities. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19607850. |
s15535 (0.01-5.0 mg/kg) mimicked 8-oh-dpat in predominantly impairing conditioned contextual fear, though with smaller effect size than 8-oh-dpat, consistent with lower efficacy at postsynaptic 5-ht(1a) receptors. |
2009-12-04 |
2023-08-12 |
mouse |
| Magdalena Zaniewska, Andrew C McCreary, Małgorzata Fili. Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. Synapse (New York, N.Y.). vol 63. issue 8. 2009-08-19. PMID:19347958. |
the present data indicate that 5-ht(2a) receptors are significant for the expression of nicotine-evoked conditioned hyperactivity. |
2009-08-19 |
2023-08-12 |
rat |
| Magdalena Zaniewska, Andrew C McCreary, Małgorzata Fili. Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. Synapse (New York, N.Y.). vol 63. issue 8. 2009-08-19. PMID:19347958. |
pharmacological stimulation of 5-ht(2a) receptors enhances the conditioned hyperlocomotion, while activation of 5-ht(2c) receptors decreases both the response to acute nicotine and conditioned hyperactivity. |
2009-08-19 |
2023-08-12 |
rat |
| D Erritzoe, V G Frokjaer, S Haugbol, L Marner, C Svarer, K Holst, W F C Baaré, P M Rasmussen, J Madsen, O B Paulson, G M Knudse. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. NeuroImage. vol 46. issue 1. 2009-08-19. PMID:19457377. |
manipulations of the serotonin levels in the brain can affect impulsive behavior and influence our reactivity to conditioned reinforcers. |
2009-08-19 |
2023-08-12 |
human |
| Cheryl L Limebeer, Devin E Litt, Linda A Parke. Effect of 5-HT3 antagonists and a 5-HT(1A) agonist on fluoxetine-induced conditioned gaping reactions in rats. Psychopharmacology. vol 203. issue 4. 2009-08-17. PMID:19082581. |
effect of 5-ht3 antagonists and a 5-ht(1a) agonist on fluoxetine-induced conditioned gaping reactions in rats. |
2009-08-17 |
2023-08-12 |
rat |
| Cheryl L Limebeer, Devin E Litt, Linda A Parke. Effect of 5-HT3 antagonists and a 5-HT(1A) agonist on fluoxetine-induced conditioned gaping reactions in rats. Psychopharmacology. vol 203. issue 4. 2009-08-17. PMID:19082581. |
the effect of manipulation of the serotonin (5-ht) system on conditioned gaping (presumably reflective of nausea in rats) was evaluated. |
2009-08-17 |
2023-08-12 |
rat |
| M E Pum, R J Carey, J P Huston, C P Mülle. Role of medial prefrontal, entorhinal, and occipital 5-HT in cocaine-induced place preference and hyperlocomotion: evidence for multiple dissociations. Psychopharmacology. vol 201. issue 3. 2009-04-07. PMID:18762916. |
the present series of studies set out to investigate the functional role of the observed increases in 5-ht in the medial prefrontal cortex (mpfc), the entorhinal cortex (ec), and the occipital cortex (occc) in the mediation of cocaine-induced conditioned place preference (cpp) and hyperactivity. |
2009-04-07 |
2023-08-12 |
human |
| Robert J Carey, Ernest N Damianopoulos, Arielle B Shanaha. Cocaine conditioning: reversal by autoreceptor dose levels of 8-OHDPAT. Pharmacology, biochemistry, and behavior. vol 91. issue 3. 2009-04-02. PMID:18804487. |
these findings are consistent with an important role for serotonin in the maintenance of cocaine pavlovian conditioned effects. |
2009-04-02 |
2023-08-12 |
rat |
| Shinji Hashimoto, Takeshi Inoue, Ihoko Muraki, Tsukasa Koyam. Effects of acute citalopram on the expression of conditioned freezing in naive versus chronic citalopram-treated rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 1. 2009-04-02. PMID:19010374. |
an acute challenge with selective serotonin (5-ht) reuptake inhibitors (ssris) reduces the conditioned freezing in rats, a model of anxiety. |
2009-04-02 |
2023-08-12 |
rat |
| Galina F Molodtsov. Serotonergic mechanisms of memory trace retrieval. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18243361. |
analysis of serotonin (5-ht) metabolism and specific binding of radioligand [(3)h]5-ht in various brain structures at different stages of a conditioned passive avoidance response in rats has demonstrated that 5-ht is involved in the processes of memory retrieval rather than in acquisition. |
2009-01-12 |
2023-08-12 |
rat |
| Galina F Molodtsov. Serotonergic mechanisms of memory trace retrieval. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18243361. |
furthermore, a memory retrieval deficit evoked by presentation of a habituated conditioned stimulus (latent inhibition) resulted in an enhanced 5-ht activity in these structures. |
2009-01-12 |
2023-08-12 |
rat |
| Bríd A Nic Dhonnchadha, Kathryn A Cunningha. Serotonergic mechanisms in addiction-related memories. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18639587. |
the 5-ht(2a)r and 5-ht(2c)r appear to be integral in the strong conditioned associations made between cocaine and environmental cues with 5-ht(2a)r antagonists and 5-ht(2c)r agonists possessing potency in blocking retrieval of cocaine-associated memories following cocaine self-administration procedures. |
2009-01-12 |
2023-08-12 |
Not clear |
| Matthew A Cooper, Kathleen E McIntyre, Kim L Huhma. Activation of 5-HT1A autoreceptors in the dorsal raphe nucleus reduces the behavioral consequences of social defeat. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18692968. |
in this study we tested the hypothesis that 5-ht activity in the dorsal raphe nucleus (drn) contributes to the acquisition and expression of conditioned defeat. |
2008-11-25 |
2023-08-12 |
Not clear |
| Matthew A Cooper, Kathleen E McIntyre, Kim L Huhma. Activation of 5-HT1A autoreceptors in the dorsal raphe nucleus reduces the behavioral consequences of social defeat. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18692968. |
these data support the hypothesis that the activity of 5-ht cells in the drn, as regulated by 5-ht1a autoreceptors, contributes to the formation and display of conditioned defeat. |
2008-11-25 |
2023-08-12 |
Not clear |
| Xuesheng Li, Yun Zhang, Xia Zhan. Tat-3L4F does not significantly affect spatial learning and memory. Behavioural brain research. vol 193. issue 2. 2008-11-03. PMID:18571742. |
we recently found that the interfering peptide tat-3l4f is able not only to disrupt the protein-protein interaction of pten (phosphatase and tensin homologue deleted on chromosome 10) with the serotonin 5-ht2c receptor in the rat ventral tegmental area (vta) but also to suppress the conditioned place preference induced by cannabinoid and nicotine without significant effects on anxiety, feeding behavior and motor activity. |
2008-11-03 |
2023-08-12 |
rat |
| Ihoko Muraki, Takeshi Inoue, Tsukasa Koyam. Effect of co-administration of the selective 5-HT1A receptor antagonist WAY 100,635 and selective 5-HT1B/1D receptor antagonist GR 127,935 on anxiolytic effect of citalopram in conditioned fear stress in the rat. European journal of pharmacology. vol 586. issue 1-3. 2008-09-02. PMID:18423441. |
this study investigated the effect of co-administration of the selective 5-ht1a receptor antagonist way 100,635 and selective 5-ht(1b/1d) receptor antagonist gr 127,935 with a subactive dose of citalopram [selective serotonin (5-ht) reuptake inhibitor (ssri)] on the expression of conditioned freezing, an index of fear. |
2008-09-02 |
2023-08-12 |
rat |
| Anna Wesołowsk. The anxiolytic-like effect of the selective 5-HT6 receptor antagonist SB-399885: the impact of benzodiazepine receptors. European journal of pharmacology. vol 580. issue 3. 2008-05-30. PMID:18096153. |
the present results suggest that the anticonflict activity of sb-399885 is not conditioned by the integrity of 5-ht neurons, and that benzodiazepine receptors are indirectly involved in its effect, possibly due to a functional interaction between 5-ht6 receptors and the gamma-aminobutyric acid (gaba)/benzodiazepine system. |
2008-05-30 |
2023-08-12 |
rat |
| C W Hodge, A M Bratt, S P Kelle. Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization. Genes, brain, and behavior. vol 7. issue 1. 2008-04-22. PMID:17559417. |
enhanced locomotor response to saline injection following cocaine sensitization was observed equally in 5-ht(3a) (-/-) and wild-type mice suggesting similar conditioned effects associated with chronic cocaine treatment. |
2008-04-22 |
2023-08-12 |
mouse |
| A J Fulford, C A Marsde. An intact dopaminergic system is required for context-conditioned release of 5-HT in the nucleus accumbens of postweaning isolation-reared rats. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17869434. |
microdialysis with high-performance liquid chromatography-electrochemical detection was used to quantify dopamine and 5-ht efflux in the nucleus accumbens following foot shock and in association with a conditioned emotional response (cer). |
2008-01-16 |
2023-08-12 |
rat |
| A J Fulford, C A Marsde. An intact dopaminergic system is required for context-conditioned release of 5-HT in the nucleus accumbens of postweaning isolation-reared rats. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17869434. |
these data suggest that unconditioned or conditioned stress-induced changes in 5-ht release of the nucleus accumbens are dependent upon intact catecholaminergic neurotransmission. |
2008-01-16 |
2023-08-12 |
rat |