| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Szu-Han Wan. Lose the fear and boost the everyday memory through memory destabilisation and reconsolidation. Brain research bulletin. 2022-10-06. PMID:36202323. |
this review primarily focuses on evidence from fear conditioning paradigms, as interfering reconsolidation of fear memory paves ways for treating post-traumatic stress disorder (ptsd). |
2022-10-06 |
2023-08-14 |
Not clear |
| Hye-Yeon Cho, Han-Sol Lee, Yire Jeong, Junho Han, Miran Yoo, Jin-Hee Ha. Excitability-Independent Memory Allocation for Repeated Event. Frontiers in behavioral neuroscience. vol 16. 2022-05-16. PMID:35571275. |
recently, we found that retraining 24 h after the initial fear conditioning (fc) event induces turnover of neurons in the lateral amygdala (la) that encodes fear memory. |
2022-05-16 |
2023-08-13 |
Not clear |
| Sizhen Su, Jiahui Deng, Kai Yuan, Yimiao Gong, Yuxin Zhang, Hui Li, Kexin Cao, Xiaolin Huang, Xiao Lin, Ping Wu, Yanxue Xue, Yanping Bao, Jie Shi, Le Shi, Lin L. Continuous theta-burst stimulation over the right dorsolateral prefrontal cortex disrupts fear memory reconsolidation in humans. iScience. vol 25. issue 1. 2022-02-02. PMID:35106462. |
succeeding fear conditioning, the subjects received ctbs over the right dorsolateral prefrontal cortex (dlpfc) or vertex (control) with or without exposure to the conditioned stimulus to reactivate the original fear memory, and then underwent fear response tests. |
2022-02-02 |
2023-08-13 |
human |
| Federico Rotondo, Kathryn Biddle, John Chen, Josh Ferencik, Mathilde d'Esneval, Amy L Milto. Lack of Effect of Propranolol on the Reconsolidation of Conditioned Fear Memory due to a Failure to Engage Memory Destabilisation. Neuroscience. vol 480. 2021-12-10. PMID:34774713. |
lack of effect of propranolol on the reconsolidation of conditioned fear memory due to a failure to engage memory destabilisation. |
2021-12-10 |
2023-08-13 |
Not clear |
| Hiroko Ikeda, Shogo Yamamoto, Junzo Kame. Increase in brain l-lactate enhances fear memory in diabetic mice: Involvement of glutamate neurons. Brain research. vol 1767. 2021-12-09. PMID:34129854. |
to clarify the mechanisms through which diabetes affects conditioned fear memory, the present study investigated the role of l-lactate and glutamatergic function in enhancement of conditioned fear memory in diabetes. |
2021-12-09 |
2023-08-13 |
mouse |
| Yeji Lee, Jung-Pyo Oh, Jin-Hee Ha. Dissociated Role of Thalamic and Cortical Input to the Lateral Amygdala for Consolidation of Long-Term Fear Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 46. 2021-11-27. PMID:34667069. |
to investigate this question, we optogenetically silenced the inputs from both auditory cortex and thalamus in the lateral amygdala (la) for 15 min immediately following auditory fear conditioning (fc) and examined its effect on fear memory formation in mice of both sexes. |
2021-11-27 |
2023-08-13 |
mouse |
| Franziska Magdalena Kausche, Gundula Zerbes, Lea Kampermann, Jana Christina Müller, Klaus Wiedemann, Christian Büchel, Lars Schwab. Noradrenergic stimulation increases fear memory expression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 43. 2021-11-19. PMID:33358539. |
these findings suggest that noradrenergic arousal strengthens fear memory expression and have important implications for mental disorders in which the overgeneralization of conditioned fear is prominent. |
2021-11-19 |
2023-08-13 |
human |
| Yoonjeong Jeon, Yun Lim, Jiwoo Yeom, Eun-Kyoung Ki. Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory. Molecular brain. vol 14. issue 1. 2021-11-18. PMID:34615530. |
comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory. |
2021-11-18 |
2023-08-13 |
Not clear |
| Weronika Szadzinska, Konrad Danielewski, Kacper Kondrakiewicz, Karolina Andraka, Evgeni Nikolaev, Marta Mikosz, Ewelina Knapsk. Hippocampal Inputs in the Prelimbic Cortex Curb Fear after Extinction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 44. 2021-11-09. PMID:34518304. |
the prelimbic cortex (pl), which integrates signals from brain structures involved in fear conditioning and extinction such as the ventral hippocampus (vhip) and the basolateral amygdala (bl), is necessary for fear memory retrieval. |
2021-11-09 |
2023-08-13 |
rat |
| Shingo Enomoto, Takahiro A Kat. Involvement of microglia in disturbed fear memory regulation: Possible microglial contribution to the pathophysiology of posttraumatic stress disorder. Neurochemistry international. vol 142. 2021-10-27. PMID:33232758. |
several preclinical studies using pavlovian fear conditioning have suggested that microglia are involved in fear memory dysregulation and altered fear neuronal networks. |
2021-10-27 |
2023-08-13 |
Not clear |
| Kayla Farrell, Madeline Musaus, Shaghayegh Navabpour, Kiley Martin, W Keith Ray, Richard F Helm, Timothy J Jarom. Proteomic Analysis Reveals Sex-Specific Protein Degradation Targets in the Amygdala During Fear Memory Formation. Frontiers in molecular neuroscience. vol 14. 2021-10-22. PMID:34658783. |
collectively, this study provides strong evidence that sex differences exist in the protein targets of the degradation process in the amygdala following fear conditioning and critical information regarding how ubiquitin-proteasome mediated protein degradation may contribute to fear memory formation in the brain. |
2021-10-22 |
2023-08-13 |
rat |
| Maria P Rysakova, Irina V Pavlova, Lyudmila V Vinogradov. Spreading depolarization induced by amygdala micro-injury prevents disruption of fear memory extinction in rats. Behavioural brain research. vol 416. 2021-10-05. PMID:34453972. |
using the classical pavlovian fear conditioning paradigm, we investigated effects of the post-retrieval amygdala micro-injury and associated sd on fear memory in rats. |
2021-10-05 |
2023-08-13 |
human |
| Sylvia K Harmon-Jones, Bronwyn M Graham, Gabrielle King, Rick Richardso. It's all about who you know: Memory retention of a rat's cagemates during infancy negatively predicts adulthood hippocampal FGF2. Neurobiology of learning and memory. vol 182. 2021-09-22. PMID:33915298. |
in the present study, we examined whether individual differences in infant fear memory predict levels of endogenous fibroblast growth factor-2 (fgf2; a biomarker of fear/anxiety) in adulthood, and whether the mean memory retention of a rat's cagemates predicts conditioned fear expression and fgf2 in adulthood. |
2021-09-22 |
2023-08-13 |
rat |
| Mariella Bodemeier Loayza Careaga, Carlos Eduardo Neves Girardi, Deborah Sucheck. Propranolol failed to prevent severe stress-induced long-term behavioral changes in male rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:32827609. |
animals were submitted to contextual fear conditioning (delayed shock group) or not (non-shock group) and underwent fear memory retrieval followed by propranolol or saline administration two weeks later. |
2021-09-02 |
2023-08-13 |
rat |
| Wiktor Bilecki, Joachim Latusz, Kinga Gawlińska, Magdalena Chmelova, Marzena Maćkowia. Prenatal MAM treatment altered fear conditioning following social isolation: Relevance to schizophrenia. Behavioural brain research. vol 406. 2021-09-02. PMID:33737089. |
the results showed that mam treatment did not alter fear memory, which was investigated with the use of either trace or delay fear conditioning, at any age, and si decreased the fear response in adult control animals only under trace conditioning. |
2021-09-02 |
2023-08-13 |
rat |
| Xiao-Cen Fan, Chao-Nan Ma, Jia-Chen Song, Zhao-Hui Liao, Nan Huang, Xing Liu, Lan M. Rac1 Signaling in Amygdala Astrocytes Regulates Fear Memory Acquisition and Retrieval. Neuroscience bulletin. vol 37. issue 7. 2021-08-18. PMID:33909243. |
in terms of the impact on fear memory retrieval, we found both up- and down-regulation of bla astrocytic rac1 activity impaired memory retrieval of fear conditioning and memory retrieval-induced neuronal activation. |
2021-08-18 |
2023-08-13 |
mouse |
| Anna Seewald, Sabine Schönherr, Heide Hörtnagl, Ingrid Ehrlich, Claudia Schmuckermair, Francesco Ferragut. Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses. Frontiers in synaptic neuroscience. vol 13. 2021-08-18. PMID:34295235. |
with this approach, we show that, following auditory fear conditioning in mice, the formation and retrieval of fear memory is linked to a significant reduction in the density of ampa receptors, particularly at spine synapses formed by inputs of the posterior intralaminar thalamic and medial geniculate nuclei onto identified itc neurons. |
2021-08-18 |
2023-08-13 |
mouse |
| Yi Luo, Zhilian Li, Qiang Tu, Liexin Xi. Metoprolol decreases retention of fear memory and facilitates long-term depression in lateral amygdala. Behavioural pharmacology. vol 31. issue 6. 2021-08-02. PMID:31860562. |
in this study, we investigated the action of β1-adrenergic receptor antagonist-metoprolol and β2-adrenergic receptor antagonist-butoxamine on the retention of conditioned fear memory and synaptic adaptation in the lateral amygdala of rats. |
2021-08-02 |
2023-08-13 |
rat |
| Chun Wang, Xu Cao, Jing Yin, Wen-Rui Gao, Wei-Ran Li, Jin-Shun Qi, Mei-Na W. [Chronic sleep deprivation exacerbates cognitive and pathological impairments in APP/PS1/tau triple transgenic Alzheimer's disease model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230948. |
the results showed that: (1) chronic sleep deprivation did not affect anxiety- (p = 0.539) and depression-like behaviors (p = 0.874) in 3xtg-ad mice; (2) chronic sleep deprivation exacerbated the impairments of object recognition memory (p < 0.001), working memory (p = 0.002) and the conditioned fear memory (p = 0.039) in 3xtg-ad mice; (3) chronic sleep deprivation increased amyloid β (aβ) deposition (p < 0.001) and microglial activation (p < 0.001) in the hippocampus of 3xtg-ad mice, without inducing abnormal tau phosphorylation and neurofibrillary tangles. |
2021-07-08 |
2023-08-13 |
mouse |
| Chun Wang, Xu Cao, Jing Yin, Wen-Rui Gao, Wei-Ran Li, Jin-Shun Qi, Mei-Na W. [Chronic sleep deprivation exacerbates cognitive and pathological impairments in APP/PS1/tau triple transgenic Alzheimer's disease model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230948. |
these results indicate that chronic sleep deprivation exacerbates the impairments of recognition memory, working memory and conditioned fear memory in 3xtg-ad mice by aggravating aβ deposition and the excessive activation of microglia in the hippocampus. |
2021-07-08 |
2023-08-13 |
mouse |