| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Douglas Asede, Asnel Joseph, McLean M Bolto. Deletion of NRXN1α impairs long-range and local connectivity in amygdala fear circuit. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32684634. |
as this circuit is tightly linked with fear regulation, we subjected nrxn1α ko and wt mice to discriminative fear conditioning and found a deficit in fear memory retrieval in nrxn1α ko mice compared with wt mice. |
2021-06-18 |
2023-08-13 |
mouse |
| Jiahui Deng, Le Shi, Kai Yuan, Ping Yao, Sijing Chen, Jianyu Que, Yimiao Gong, Yanping Bao, Jie Shi, Ying Han, Hongqiang Sun, Lin L. Propranolol-induced inhibition of unconditioned stimulus-reactivated fear memory prevents the return of fear in humans. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:33051441. |
all of the subjects acquired fear conditioning, after which they received the β-adrenergic receptor antagonist propranolol (40 mg) or placebo (vitamin c) and were exposed to the us or cs to reactivate the original fear memory. |
2021-06-18 |
2023-08-13 |
human |
| Sreetama Basu, Jessica M Alapin, Monica Dines, Raphael Lamprech. Long-term memory is maintained by continuous activity of Arp2/3 in lateral amygdala. Neurobiology of learning and memory. vol 167. 2021-01-22. PMID:31733301. |
to test this hypothesis we microinjected into lateral amygdala (la) of rats ck-666, a specific inhibitor of arp2/3, two days after fear conditioning and tested the effect on long-term fear memory maintenance a day afterward. |
2021-01-22 |
2023-08-13 |
rat |
| Miran Yoo, Seongwan Park, Inkyung Jung, Jin-Hee Ha. Persistence of Fear Memory Depends on a Delayed Elevation of BAF53b and FGF1 Expression in the Lateral Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 37. 2021-01-19. PMID:32817243. |
in the previous study, we found that baf53b, a neuron-specific subunit of baf chromatin remodeling complex, is induced after auditory cued fear conditioning in the lateral amygdala (la) and is crucial for recent fear memory formation. |
2021-01-19 |
2023-08-13 |
mouse |
| Muhammad Asim, Bo Hao, Yu-Han Yang, Bu-Fang Fan, Li Xue, Yan-Wei Shi, Xiao-Guang Wang, Hu Zha. Ketamine Alleviates Fear Generalization Through GluN2B-BDNF Signaling in Mice. Neuroscience bulletin. vol 36. issue 2. 2020-12-17. PMID:31444653. |
these findings support the conclusion that a single dose of ketamine administered 22 h after fear conditioning alleviates the fear memory generalization in mice and the glun2b-related bdnf signaling pathway plays an important role in the alleviation of fear generalization. |
2020-12-17 |
2023-08-13 |
mouse |
| Saida Haider, Zehra Batool, Sahar Rafi. Method for the identification of pharmacological intervention for the disruption of fear memory in PTSD-rat model. MethodsX. vol 7. 2020-10-02. PMID:32995310. |
in this article, we are presenting a detailed method of pavlovian fear conditioning which we have optimized in our lab for the identification of drugs having the potential to disrupt fear memory in the ptsd-rat model. |
2020-10-02 |
2023-08-13 |
human |
| Antonio V Aubry, Peter A Serrano, Nesha S Burghard. Molecular Mechanisms of Stress-Induced Increases in Fear Memory Consolidation within the Amygdala. Frontiers in behavioral neuroscience. vol 10. 2020-10-01. PMID:27818625. |
here we review the literature on the enhancing effects of acute and chronic stress on the acquisition and/or consolidation of a fear memory, as measured by auditory pavlovian fear conditioning, and discuss potential mechanisms by which these changes occur in the amygdala. |
2020-10-01 |
2023-08-13 |
human |
| Zhaohui Liao, Yezheng Tao, Xiaomu Guo, Deqin Cheng, Feifei Wang, Xing Liu, Lan M. Fear Conditioning Downregulates Rac1 Activity in the Basolateral Amygdala Astrocytes to Facilitate the Formation of Fear Memory. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:29230165. |
fear conditioning downregulates rac1 activity in the basolateral amygdala astrocytes to facilitate the formation of fear memory. |
2020-10-01 |
2023-08-13 |
mouse |
| Olga O Kozanian, David J Rohac, Niusha Bavadian, Alex Corches, Edward Korzus, Kelly J Huffma. Long-Lasting Effects of Prenatal Ethanol Exposure on Fear Learning and Development of the Amygdala. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30233337. |
to test whether pree alters development of brain circuitry associated with fear conditioning and fear memory recall, we histologically examined subdivisions of the amygdala in pree and control mice and found long-term effects of pree on fear memory circuitry. |
2020-10-01 |
2023-08-13 |
mouse |
| Maxwell R Bennett, Les Farnell, William G Gibson, Jim Lagopoulo. A model of amygdala function following plastic changes at specific synapses during extinction. Neurobiology of stress. vol 10. 2020-09-29. PMID:31193487. |
pavlovian fear conditioning generates a fear memory in the lateral amygdala module that leads to activation of neurons in the basal nucleus fear module but not in the basal nucleus extinction module. |
2020-09-29 |
2023-08-13 |
human |
| Ivana Brito, Luiz Roberto G Britto, Elenice Aparecida M Ferrar. Retrieval of contextual aversive memory and induction of Zenk expression in the hippocampus of pigeons. Brain research bulletin. vol 153. 2020-09-24. PMID:31586459. |
these data suggest that zenk-mediated processes of synaptic plasticity in the hippocampus are induced during the retrieval of conditioned fear memory in the pigeon. |
2020-09-24 |
2023-08-13 |
pigeon |
| Sahar Rafiq, Zehra Batool, Laraib Liaquat, Saida Haide. Blockade of muscarinic receptors impairs reconsolidation of older fear memory by decreasing cholinergic neurotransmission: A study in rat model of PTSD. Life sciences. vol 256. 2020-08-31. PMID:32593712. |
the present study was therefore designed to compare the effects of atropine and propranolol on reconsolidation of older fear memory in rat model of ptsd using pavlovian fear conditioning apparatus. |
2020-08-31 |
2023-08-13 |
rat |
| Damien Bonhomme, Serge Alfos, Scott P Webster, Mathieu Wolff, Véronique Pallet, Katia Touyaro. Vitamin A deficiency impairs contextual fear memory in rats: Abnormalities in the glucocorticoid pathway. Journal of neuroendocrinology. vol 31. issue 11. 2020-08-19. PMID:31613407. |
however, it is unknown whether vitamin a status also modulates contextual fear conditioning (cfc) in a glucocorticoid-associated fear memory task dependent on the functional integrity of the hippocampus. |
2020-08-19 |
2023-08-13 |
rat |
| Xiangyu Zhang, Joshua Kim, Susumu Tonegaw. Amygdala Reward Neurons Form and Store Fear Extinction Memory. Neuron. vol 105. issue 6. 2020-07-14. PMID:31952856. |
the ability to extinguish conditioned fear memory is critical for adaptive control of fear response, and its impairment is a hallmark of emotional disorders like post-traumatic stress disorder (ptsd). |
2020-07-14 |
2023-08-13 |
Not clear |
| Woong Bin Kim, Jun-Hyeong Ch. Encoding of contextual fear memory in hippocampal-amygdala circuit. Nature communications. vol 11. issue 1. 2020-07-13. PMID:32170133. |
here, we show that activity in the ventral ca1 (vca1) hippocampal projections to the basal amygdala (ba), paired with aversive stimuli, contributes to encoding conditioned fear memory. |
2020-07-13 |
2023-08-13 |
human |
| Mohammad Nasehi, Ameneh Mohammadi, Mohaddeseh Ebrahimi-Ghiri, Mehrdad Hashemi, Mohammad-Reza Zarrindas. MLC901 during sleep deprivation rescues fear memory disruption in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 7. 2020-05-20. PMID:30820610. |
in the present study, saline- or mlc901 (a traditional chinese medicine)-treated male wistar rats were first submitted to a modified water box (for 24-h sleep deprivation) and then trained in contextual and tone fear conditioning tasks with the purpose to evaluate the effect of mlc901 during sleep deprivation on fear memory retention. |
2020-05-20 |
2023-08-13 |
rat |
| Georgia M Alexander, Natallia V Riddick, Katharine E McCann, Daniel Lustberg, Sheryl S Moy, Serena M Dude. Modulation of CA2 neuronal activity increases behavioral responses to fear conditioning in female mice. Neurobiology of learning and memory. vol 163. 2020-04-02. PMID:31319167. |
finally, we tested fear conditioning in rgs14 ko mice and found that female ko mice had increased freezing on the cued fear memory test. |
2020-04-02 |
2023-08-13 |
mouse |
| Claire Meissner-Bernard, Yulia Dembitskaya, Laurent Venance, Alexander Fleischman. Encoding of Odor Fear Memories in the Mouse Olfactory Cortex. Current biology : CB. vol 29. issue 3. 2020-02-25. PMID:30612908. |
furthermore, chemogenetic reactivation of piriform neurons that were fos tagged during olfactory fear conditioning causes a decrease in exploratory behavior, mimicking odor-evoked fear memory recall. |
2020-02-25 |
2023-08-13 |
mouse |
| Edward G Meloni, Karen T Kaye, Archana Venkataraman, William A Carlezo. PACAP increases Arc/Arg 3.1 expression within the extended amygdala after fear conditioning in rats. Neurobiology of learning and memory. vol 157. 2019-11-25. PMID:30458282. |
given the established role of arc in modifying synaptic plasticity and memory formation, our findings suggest that pacap-induced overexpression of arc following fear conditioning may disrupt neuroplastic changes within populations of cea and bnst neurons normally responsible for encoding fear-related cues that, in this case, results in altered fear memory consolidation. |
2019-11-25 |
2023-08-13 |
rat |
| Jennifer M Staib, Rebecca Della Valle, Dayan K Kno. Disruption of medial septum and diagonal bands of Broca cholinergic projections to the ventral hippocampus disrupt auditory fear memory. Neurobiology of learning and memory. vol 152. 2019-10-01. PMID:29783059. |
in classical fear conditioning, a neutral conditioned stimulus (cs) is paired with an aversive unconditioned stimulus (us), which leads to a fear memory. |
2019-10-01 |
2023-08-13 |
Not clear |