| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donald F Siwek, Clifford M Knapp, Gurcharan Kaur, Subimal Datt. Dorsal subcoeruleus nucleus (SubCD) involvement in context-associated fear memory consolidation. Experimental brain research. vol 232. issue 5. 2014-12-17. PMID:24525958. |
in rodents, some of this evidence comes from a common finding that sleep deprivation from 0 to 6 h after fear conditioning training impairs processing of conditioned fear memory. |
2014-12-17 |
2023-08-12 |
rat |
| R Ferreira, M J Nobr. Conditioned fear in low- and high-anxious rats is differentially regulated by cortical subcortical and midbrain 5-HT(1A) receptors. Neuroscience. vol 268. 2014-12-12. PMID:24657773. |
interactions between the prelimbic cortex and the basolateral amygdala underlie fear memory processing, mostly through acquiring and consolidating the learning of a conditioned fear. |
2014-12-12 |
2023-08-12 |
human |
| Brian George Dias, Jared Vega Goodman, Ranbir Ahluwalia, Audrey Elizabeth Easton, Raül Andero, Kerry James Ressle. Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling. Neuron. vol 83. issue 4. 2014-12-11. PMID:25123309. |
using an array-based approach after auditory fear conditioning and microrna (mirna) sponge-mediated inhibition, we identified a role for mir-34a within the basolateral amygdala (bla) in fear memory consolidation. |
2014-12-11 |
2023-08-13 |
Not clear |
| Lizhu Jiang, Chen Liu, Jianbin Tong, Rongrong Mao, Dan Chen, Hui Wang, Jufang Huang, Lingjiang L. Fluoxetine pretreatment promotes neuronal survival and maturation after auditory fear conditioning in the rat amygdala. PloS one. vol 9. issue 2. 2014-10-14. PMID:24551236. |
in rats showing persistent auditory fear memory following fear conditioning, we found that the survival of new-born cells and the number of new-born cells that differentiated into mature neurons labeled by brdu and neun decreased in the amygdala, but the number of cells that developed into astrocytes labeled by brdu and gfap increased. |
2014-10-14 |
2023-08-12 |
rat |
| Lizhu Jiang, Chen Liu, Jianbin Tong, Rongrong Mao, Dan Chen, Hui Wang, Jufang Huang, Lingjiang L. Fluoxetine pretreatment promotes neuronal survival and maturation after auditory fear conditioning in the rat amygdala. PloS one. vol 9. issue 2. 2014-10-14. PMID:24551236. |
chronic pretreatment with flx partially rescued the reduction in neurogenesis in the amygdala and slightly suppressed the maintenance of the long-lasting auditory fear memory 30 days after the fear conditioning. |
2014-10-14 |
2023-08-12 |
rat |
| Stephanie A Maddox, Casey S Watts, Glenn E Schaf. DNA methyltransferase activity is required for memory-related neural plasticity in the lateral amygdala. Neurobiology of learning and memory. vol 107. 2014-09-05. PMID:24291571. |
we have previously shown that auditory pavlovian fear conditioning is associated with an increase in dna methyltransferase (dnmt) expression in the lateral amygdala (la) and that intra-la infusion or bath application of an inhibitor of dnmt activity impairs the consolidation of an auditory fear memory and long-term potentiation (ltp) at thalamic and cortical inputs to the la, in vitro. |
2014-09-05 |
2023-08-12 |
Not clear |
| Nicola J Broadbent, Robert E Clar. Remote context fear conditioning remains hippocampus-dependent irrespective of training protocol, training-surgery interval, lesion size, and lesion method. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:23994542. |
accordingly, we evaluated classically conditioned fear memory in large groups of rats with hippocampal damage by manipulating several procedural variables including the training protocol, the training-surgery interval, the extent of hippocampal damage, and the method of damaging the hippocampus. |
2014-08-11 |
2023-08-12 |
rat |
| Xu Liu, Steve Ramirez, Susumu Tonegaw. Inception of a false memory by optogenetic manipulation of a hippocampal memory engram. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298144. |
here, we first identified a population of cells in the dentate gyrus (dg) of the hippocampus that bear the engrams for a specific context; these cells were naturally activated during the encoding phase of fear conditioning and their artificial reactivation using optogenetics in an unrelated context was sufficient for inducing the fear memory specific to the conditioned context. |
2014-08-11 |
2023-08-12 |
Not clear |
| Makoto Kondo, Yukiko Nakamura, Yusuke Ishida, Takahiro Yamada, Shoichi Shimad. The 5-HT3A receptor is essential for fear extinction. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 1. 2014-08-11. PMID:24344177. |
analysis of 5-ht3a receptor knockout mice in fear conditioning paradigms revealed that the 5-ht3a receptor is not required for the acquisition or retention of fear memory but is essential for the extinction of contextual and tone-cued fear. |
2014-08-11 |
2023-08-12 |
mouse |
| Matthew R Durk, Kyung Han, Edwin C Y Chow, Rosemary Ahrens, Jeffrey T Henderson, Paul E Fraser, K Sandy Pan. 1α,25-Dihydroxyvitamin D3 reduces cerebral amyloid-β accumulation and improves cognition in mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 21. 2014-07-11. PMID:24849345. |
long-term treatment of tgcrnd8 mice with 1,25(oh)2d3 during the period of plaque formation reduced soluble and insoluble plaque-associated aβ, particularly in the hippocampus in which the vdr is abundant and p-gp induction is greatest after 1,25(oh)2d3 treatment, and this led to improved conditioned fear memory. |
2014-07-11 |
2023-08-13 |
mouse |
| K McEown, D Trei. Α2 GABAA receptor sub-units in the ventral hippocampus and α5 GABAA receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory. Neuroscience. vol 252. 2014-06-11. PMID:23962649. |
this double dissociation suggests that α2 gabaa receptor sub-units in the ventral hippocampus mediate unconditioned fear or anxiety, while α5 gabaa receptor sub-units in the dorsal hippocampus mediate conditioned fear memory. |
2014-06-11 |
2023-08-12 |
rat |
| Georgette M Gafford, Ryan G Parsons, Fred J Helmstette. Memory accuracy predicts hippocampal mTOR pathway activation following retrieval of contextual fear memory. Hippocampus. vol 23. issue 9. 2014-04-09. PMID:23640842. |
we tested whether p70s6 kinase (p70s6k), a key component of the mtor signaling pathway, is activated following retrieval of context fear memory in the dorsal hippocampus (dh) and anterior cingulate cortex (acc) at 1, 10, or 36 days after context fear conditioning. |
2014-04-09 |
2023-08-12 |
Not clear |
| Cesar Augusto de Oliveira Coelho, Tatiana Lima Ferreira, Juliana Carlota Kramer Soares, Maria Gabriela Menezes Oliveir. Hippocampal NMDA receptor blockade impairs CREB phosphorylation in amygdala after contextual fear conditioning. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23460450. |
in contextual fear conditioning (cfc), hippocampus is thought to process environmental stimuli into a configural representation of the context and send it to amygdala nuclei, which current evidences point to be the site of cs-us association and fear memory storage. |
2014-01-23 |
2023-08-12 |
rat |
| Philip R Corlett, Victoria Cambridge, Jennifer M Gardner, Jennifer S Piggot, Danielle C Turner, Jessica C Everitt, Fernando Sergio Arana, Hannah L Morgan, Amy L Milton, Jonathan L Lee, Michael R F Aitken, Anthony Dickinson, Barry J Everitt, Anthony R Absalom, Ram Adapa, Naresh Subramanian, Jane R Taylor, John H Krystal, Paul C Fletche. Ketamine effects on memory reconsolidation favor a learning model of delusions. PloS one. vol 8. issue 6. 2014-01-23. PMID:23776445. |
we determined the influence of this nmda receptor antagonist (previously shown to induce aberrant prediction error signal and lead to transient alterations in perception and belief) on the evolution of a fear memory over a 72 hour period: they initially underwent pavlovian fear conditioning; 24 hours later, during ketamine or placebo administration, the conditioned stimulus (cs) was presented once, without reinforcement; memory strength was then tested again 24 hours later. |
2014-01-23 |
2023-08-12 |
human |
| Shingo Matsuda, Daisuke Matsuzawa, Daisuke Ishii, Haruna Tomizawa, Junko Sajiki, Eiji Shimiz. Perinatal exposure to bisphenol A enhances contextual fear memory and affects the serotoninergic system in juvenile female mice. Hormones and behavior. vol 63. issue 5. 2014-01-17. PMID:23567477. |
in this study, we investigated the effects of bpa (250 ng/kg/day, from gestational day 10 to postnatal day 20) on fear memory and serotonin (5-ht) metabolites in the brain using contextual fear conditioning (fc) and high-performance liquid chromatography (hplc), respectively, in adult and juvenile mice of both sexes. |
2014-01-17 |
2023-08-12 |
mouse |
| Kaja Ewa Moczulska, Juliane Tinter-Thiede, Manuel Peter, Lyubov Ushakova, Tanja Wernle, Brice Bathellier, Simon Rumpe. Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 45. 2013-12-31. PMID:24151334. |
our findings provide a synaptic mechanism for plasticity in sound responses of auditory cortex neurons induced by auditory-cued fear conditioning; they also show that retrieval of an auditory fear memory does not lead to a recapitulation of structural plasticity in the auditory cortex as observed during initial memory consolidation. |
2013-12-31 |
2023-08-12 |
mouse |
| Hsu-Wen Chao, Li-Yun Tsai, Yi-Ling Lu, Pei-Yi Lin, Wen-Hsuan Huang, Hsin-Jung Chou, Wen-Hsin Lu, Hsiu-Chen Lin, Ping-Tao Lee, Yi-Shuian Huan. Deletion of CPEB3 enhances hippocampus-dependent memory via increasing expressions of PSD95 and NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 43. 2013-12-23. PMID:24155305. |
to understand whether cpeb3 plays a part in learning and memory, we generated cpeb3 knock-out (ko) mice and found that the null mice exhibited enhanced hippocampus-dependent, short-term fear memory in the contextual fear conditioning test and long-term spatial memory in the morris water maze. |
2013-12-23 |
2023-08-12 |
mouse |
| Christopher L Beeman, Philip S Bauer, Jamie L Pierson, Jennifer J Quin. Hippocampus and medial prefrontal cortex contributions to trace and contextual fear memory expression over time. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 6. 2013-12-19. PMID:23685809. |
previous work has shown that damage to the dorsal hippocampus (dh) occurring at recent, but not remote, timepoints following acquisition produces a deficit in trace conditioned fear memory expression. |
2013-12-19 |
2023-08-12 |
Not clear |
| Judith R Homber. Serotonergic modulation of conditioned fear. Scientifica. vol 2012. 2013-11-26. PMID:24278743. |
the human and rodent studies i review here together reveal, amongst others, that acute selective serotonin reuptake inhibitor (ssri) treatment facilitates fear conditioning, reduces contextual fear, and increases cued fear, chronic ssri treatment reduces both contextual and cued fear, 5-ht1a receptors inhibit the acquisition and expression of contextual fear, 5-ht2a receptors facilitates the consolidation of cued and contextual fear, inactivation of 5-ht2c receptors facilitate the retrieval of cued fear memory, the 5-ht3 receptor mediates contextual fear, genetically induced increases in serotonin levels are associated with increased fear conditioning, impaired cued fear extinction, or impaired extinction recall, and that genetically induced 5-ht depletion increases fear conditioning and contextual fear. |
2013-11-26 |
2023-08-12 |
human |
| Karine Gamache, Roger K Pitman, Karim Nade. Preclinical evaluation of reconsolidation blockade by clonidine as a potential novel treatment for posttraumatic stress disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 13. 2013-08-26. PMID:22871915. |
using an auditory fear conditioning paradigm in rats, we tested the efficacy of clonidine to weaken fear memory retention when administered systemically after retrieval. |
2013-08-26 |
2023-08-12 |
rat |