| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Zeng, Yakun Liu, Mianyun Wu, Jun Liu, Qi H. Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging. Journal of Alzheimer's disease : JAD. vol 31. issue 4. 2013-07-08. PMID:22710915. |
the results show that chronic 7,8-dhf treatments significantly enhanced the activation of phosphorylated trkb at the y515 and y816 sites, increased spine density and number in several brain regions that process fear memory including the amygdala, hippocampus, and prefrontal cortex, facilitated basolateral amygdalar synaptic plasticity, and in turn prevented performance in fear conditioning tasks from declining. |
2013-07-08 |
2023-08-12 |
rat |
| Stephanie A Maddox, Casey S Watts, Glenn E Schaf. p300/CBP histone acetyltransferase activity is required for newly acquired and reactivated fear memories in the lateral amygdala. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 2. 2013-07-01. PMID:23328899. |
we show that local infusions of c646, a selective pharmacological inhibitor of p300/cbp activity, shortly following either fear conditioning or fear memory retrieval impair training and retrieval-related regulation of histone acetylation in the lateral nucleus of the amygdala (la). |
2013-07-01 |
2023-08-12 |
Not clear |
| Jafar Alijan-Pour, Kataneh Abrari, Taghi Lashkar Bluki, Mohammad Taghi Ghorbanian, Iran Goudarzi, Mahmoud Elahdadi Salman. Ethanol disrupts reactivated contextual conditioned fear memory: behavioral and histological perspectives. Cell journal. vol 13. issue 4. 2013-03-20. PMID:23507995. |
ethanol disrupts reactivated contextual conditioned fear memory: behavioral and histological perspectives. |
2013-03-20 |
2023-08-12 |
rat |
| Jeong-Tae Kwon, Jinho Jhang, Hyung-Su Kim, Sujin Lee, Jin-Hee Ha. Brain region-specific activity patterns after recent or remote memory retrieval of auditory conditioned fear. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 10. 2013-02-22. PMID:22993170. |
although evidence has established that the amygdala is a key brain site for memory storage and retrieval of auditory conditioned fear memory, it remains elusive whether the auditory brain regions may be involved in fear memory storage or retrieval. |
2013-02-22 |
2023-08-12 |
Not clear |
| Jeong-Tae Kwon, Jinho Jhang, Hyung-Su Kim, Sujin Lee, Jin-Hee Ha. Brain region-specific activity patterns after recent or remote memory retrieval of auditory conditioned fear. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 10. 2013-02-22. PMID:22993170. |
taken together, our results support that the lateral amygdala is a key brain site for permanent fear memory storage and suggest that mgm/pin and auv/tea might play a role for remote memory storage or retrieval of auditory conditioned fear, or, alternatively, that these auditory brain regions might have a different way of processing for familiar or conditioned tone information at recent and remote time phases. |
2013-02-22 |
2023-08-12 |
Not clear |
| K Takuma, H Mizoguchi, Y Funatsu, Y Hoshina, Y Himeno, E Fukuzaki, Y Kitahara, S Arai, D Ibi, H Kamei, T Matsuda, K Koike, M Inoue, T Nagai, K Yamad. Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice. Neuroscience. vol 207. 2012-11-27. PMID:22314316. |
combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice. |
2012-11-27 |
2023-08-12 |
mouse |
| K Takuma, H Mizoguchi, Y Funatsu, Y Hoshina, Y Himeno, E Fukuzaki, Y Kitahara, S Arai, D Ibi, H Kamei, T Matsuda, K Koike, M Inoue, T Nagai, K Yamad. Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice. Neuroscience. vol 207. 2012-11-27. PMID:22314316. |
these data suggest that cholinergic dysfunction may be involved in the ovx/cs-induced conditioned fear memory impairment. |
2012-11-27 |
2023-08-12 |
mouse |
| Valentina Echeverria Mora. Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption. Frontiers in pharmacology. vol 3. 2012-10-23. PMID:23087643. |
in addition, at the preclinical level, cotinine facilitated the extinction of fear memory and anxiety after fear conditioning, improved working memory in a mouse model of alzheimer's disease (ad) and in a monkey model of schizophrenia. |
2012-10-23 |
2023-08-12 |
mouse |
| Thomas Agren, Jonas Engman, Andreas Frick, Johannes Björkstrand, Elna-Marie Larsson, Tomas Furmark, Mats Fredrikso. Disruption of reconsolidation erases a fear memory trace in the human amygdala. Science (New York, N.Y.). vol 337. issue 6101. 2012-10-09. PMID:22997340. |
using functional brain imaging, we found that, after a conditioned fear memory was formed, reactivation and reconsolidation left a memory trace in the basolateral amygdala that predicted subsequent fear expression and was tightly coupled to activity in the fear circuit of the brain. |
2012-10-09 |
2023-08-12 |
human |
| Yossef Itzhak, Karen L Anderson, Jonathan B Kelley, Martin Petko. Histone acetylation rescues contextual fear conditioning in nNOS KO mice and accelerates extinction of cued fear conditioning in wild type mice. Neurobiology of learning and memory. vol 97. issue 4. 2012-09-17. PMID:22452925. |
a single administration of nab prior to fear conditioning (a) rescued contextual fear conditioning of nnos ko mice and (b) had long-term (weeks) facilitatory effect on the extinction of cued fear memory of wt mice. |
2012-09-17 |
2023-08-12 |
mouse |
| Yuan-Chang Hsu, Lung Yu, Hsiun-ing Chen, Hui-Ling Lee, Yu-Min Kuo, Chauying J Je. Blood pressure variations real-time reflect the conditioned fear learning and memory. PloS one. vol 7. issue 4. 2012-08-21. PMID:22496737. |
our results showed that (i) the conditioned fear learning during the training sessions was reflected by light (cs)-induced rapid bp elevations and by electric shock (us)-evoked sympathetic tone elevations; (ii) these two bp-related parameters were not only negatively correlated with each other but also coupled to each other in the training session trials; (iii) both parameters closely predicted the performance of fear-potentiated startle on the next day; and (iv) although local blocking of one of the two fear-conditioned pathways in the training session partially inhibited fear learning, the fear memory retrieval still used both pathways. |
2012-08-21 |
2023-08-12 |
rat |
| María Eugenia Bertotto, Noelia Martina Maldonado, Elena Anahi Bignante, Silvana Vanesa Gorosito, María Julia Cambiasso, Víctor Alejandro Molina, Irene Delia Martijen. ERK activation in the amygdala and hippocampus induced by fear conditioning in ethanol withdrawn rats: modulation by MK-801. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 12. 2012-08-20. PMID:21315561. |
in order to explore the neural substrates and the potential mechanism involved in this effect, we examined: 1) the erk1/2 activation in the central (cea) and basolateral (bla) nuclei of the amygdala and in the dorsal hippocampus (dhip), 2) the effect of the nmda receptor antagonist mk-801 on fear conditioning and erk activation and 3) the effect of the infusion of u0126, a mek inhibitor, into the bla on fear memory formation in ethanol withdrawn rats. |
2012-08-20 |
2023-08-12 |
rat |
| Kristopher McEown, Dallas Trei. Mineralocorticoid receptors in the medial prefrontal cortex and hippocampus mediate rats' unconditioned fear behaviour. Hormones and behavior. vol 60. issue 5. 2012-03-09. PMID:21889941. |
in spite of the known roles of the hippocampus in spatial memory and conditioned fear memory, mrs within these sites did not appear to mediate memory of the shock-probe. |
2012-03-09 |
2023-08-12 |
rat |
| Ingie Hong, Jihye Kim, Junuk Lee, Sungmo Park, Beomjong Song, Jeongyeon Kim, Bobae An, Kyungjoon Park, Hyun Woo Lee, Seungbok Lee, Hyun Kim, Sang-Hyun Park, Khee Dong Eom, Sukwon Lee, Sukwoo Cho. Reversible plasticity of fear memory-encoding amygdala synaptic circuits even after fear memory consolidation. PloS one. vol 6. issue 9. 2012-03-01. PMID:21949700. |
to test this, we employed a protocol of auditory fear conditioning which recruited the vast majority of the thalamic input synaptic circuit to the lateral amygdala (t-la synaptic circuit; a storage site for fear memory) with fear conditioning-induced synaptic plasticity. |
2012-03-01 |
2023-08-12 |
rat |
| Ana Montero-Pedrazuela, Iván Fernández-Lamo, María Alieva, Inmaculada Pereda-Pérez, César Venero, Ana Guadaño-Ferra. Adult-onset hypothyroidism enhances fear memory and upregulates mineralocorticoid and glucocorticoid receptors in the amygdala. PloS one. vol 6. issue 10. 2012-02-28. PMID:22039511. |
the potentiation of emotional memory under hypothyroidism was associated with an increase of corticosterone release after fear conditioning and with higher expression of glucocorticoid and mineralocorticoid receptors in the lateral and basolateral nuclei of the amygdala, nuclei that are critically involved in the circuitry of fear memory. |
2012-02-28 |
2023-08-12 |
rat |
| Jun-Hyeong Cho, Ildar T Bayazitov, Edward G Meloni, Karyn M Myers, William A Carlezon, Stanislav S Zakharenko, Vadim Y Bolshako. Coactivation of thalamic and cortical pathways induces input timing-dependent plasticity in amygdala. Nature neuroscience. vol 15. issue 1. 2012-02-14. PMID:22158512. |
long-term synaptic enhancements in cortical and thalamic auditory inputs to the lateral nucleus of the amygdala (lan) mediate encoding of conditioned fear memory. |
2012-02-14 |
2023-08-12 |
rat |
| Marieke Soeter, Merel Kind. Noradrenergic enhancement of associative fear memory in humans. Neurobiology of learning and memory. vol 96. issue 2. 2011-12-27. PMID:21624479. |
here, we tested whether noradrenaline strengthens the emotional expression of associative fear memory by using a differential fear conditioning procedure in humans. |
2011-12-27 |
2023-08-12 |
Not clear |
| Hadley C Bergstrom, Craig G McDonald, Luke R Johnso. Pavlovian fear conditioning activates a common pattern of neurons in the lateral amygdala of individual brains. PloS one. vol 6. issue 1. 2011-08-02. PMID:21264324. |
here we used spatial principal components analysis to quantify the topography of activated neurons, in a select region of the lateral amygdala, from rat brains encoding a pavlovian conditioned fear memory. |
2011-08-02 |
2023-08-12 |
rat |
| Hadley C Bergstrom, Craig G McDonald, Luke R Johnso. Pavlovian fear conditioning activates a common pattern of neurons in the lateral amygdala of individual brains. PloS one. vol 6. issue 1. 2011-08-02. PMID:21264324. |
our results demonstrate a stable, spatially patterned organization of amygdala neurons are activated during the formation of a pavlovian conditioned fear memory. |
2011-08-02 |
2023-08-12 |
rat |
| Ingie Hong, Beomjong Song, Sukwon Lee, Jihye Kim, Jeongyeon Kim, Sukwoo Cho. Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala. The European journal of neuroscience. vol 30. issue 11. 2011-06-06. PMID:20128847. |
the amygdala is known to be a critical storage site of conditioned fear memory. |
2011-06-06 |
2023-08-12 |
rat |