| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jo E Lewis, Danae Nuzzaci, Paula-Peace James-Okoro, Mireia Montaner, Elisabeth O'Flaherty Rottenberger, Tamana Darwish, Marito Hayashi, Stephen D Liberles, David Hornigold, Jacqueline Naylor, David Baker, Fiona M Gribble, Frank Reiman. Stimulating intestinal GIP release reduces food intake and body weight in mice. Molecular metabolism. 2024-04-23. PMID:38653401. |
stimulating intestinal gip release reduces food intake and body weight in mice. |
2024-04-23 |
2024-04-26 |
mouse |
| Seun Akindehin, Arkadiusz Liskiewicz, Daniela Liskiewicz, Miriam Bernecker, Cristina Garcia-Caceres, Daniel J Drucker, Brian Finan, Gerald Grandl, Robert Gutgesell, Susanna M Hofmann, Ahmed Khalil, Xue Liu, Perla Cota, Mostafa Bakhti, Oliver Czarnecki, Aimée Bastidas-Ponce, Heiko Lickert, Lingru Kang, Gandhari Maity, Aaron Novikoff, Sebastian Parlee, Ekta Pathak, Sonja C Schriever, Michael Sterr, Siegfried Ussar, Qian Zhang, Richard DiMarchi, Matthias H Tschöp, Paul T Pfluger, Jonathan D Douros, Timo D Mülle. Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice. Molecular metabolism. 2024-03-16. PMID:38492844. |
loss of gipr in lepr cells impairs glucose control by gip and gip:glp-1 co-agonism without affecting body weight and food intake in mice. |
2024-03-16 |
2024-03-19 |
mouse |
| Dorte B Zilstorff, Michael M Richter, Jens Hannibal, Henrik L Jørgensen, Henriette P Sennels, Nicolai J Wewer Albrechtse. Secretion of glucagon, GLP-1 and GIP may be affected by circadian rhythm in healthy males. BMC endocrine disorders. vol 24. issue 1. 2024-03-14. PMID:38481208. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are secreted from gut endocrine cells during meals and control glucose homeostasis by potentiating insulin secretion and inhibiting food intake. |
2024-03-14 |
2024-03-16 |
Not clear |
| Marta Santos Hernandez, Frank Reimann, Fiona M Gribbl. Cellular mechanisms of incretin hormone secretion. Journal of molecular endocrinology. 2024-01-19. PMID:38240302. |
the incretin hormones glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are involved in the regulation of insulin secretion, appetite, food intake and body weight after their nutrient-induced secretion from the gut. |
2024-01-19 |
2024-01-21 |
Not clear |
| Rikke Viggers, Nicklas Højgaard-Hessellund Rasmussen, Peter Vestergaar. Effects of Incretin Therapy on Skeletal Health in Type 2 Diabetes-A Systematic Review. JBMR plus. vol 7. issue 11. 2023-12-01. PMID:38025038. |
the group of hormones known as incretins, which includes gastric inhibitory peptide (gip) and glucagon-like peptide 1 (glp-1), play a role in regulating bowel function and insulin secretion during feeding. |
2023-12-01 |
2023-12-07 |
human |
| Rikke Viggers, Nicklas Højgaard-Hessellund Rasmussen, Peter Vestergaar. Effects of Incretin Therapy on Skeletal Health in Type 2 Diabetes-A Systematic Review. JBMR plus. vol 7. issue 11. 2023-12-01. PMID:38025038. |
the group of hormones known as incretins, which includes gastric inhibitory peptide (gip) and glucagon-like peptide 1 (glp-1), play a role in regulating bowel function and insulin secretion during feeding. |
2023-11-29 |
2023-12-07 |
human |
| Sara Becerril, Javier A Cienfuegos, Amaia Rodríguez, Victoria Catalán, Beatriz Ramírez, Víctor Valentí, Rafael Moncada, Xabier Unamuno, Javier Gómez-Ambrosi, Gema Frühbec. Single anastomosis duodeno-ileal bypass with sleeve gastrectomy generates sustained improvement of glycemic control compared with sleeve gastrectomy in the diet-induced obese rat model. Journal of physiology and biochemistry. 2023-11-07. PMID:37935948. |
body weight and food intake were weekly monitored, and 6 weeks after interventions, fasting plasma glucose, oral glucose and insulin tolerance tests, plasma insulin, adiponectin, gip, glp-1, and ghrelin levels were determined.the body weight of sadi-s rats was significantly (p < 0.001) lower as compared to the sham-operated, sg, and pair-fed groups. |
2023-11-07 |
2023-11-20 |
rat |
| Aaron Hengist, Christina M Sciarrillo, Juen Guo, Mary Walter, Kevin D Hal. Discordance between gut-derived appetite hormones and energy intake in humans. medRxiv : the preprint server for health sciences. 2023-07-10. PMID:37425848. |
ghrelin increases hunger and decreases after food intake, whereas satiation and satiety are induced by peptide yy (pyy), glucagon-like peptide-1 (glp-1), and perhaps glucose-dependent insulinotropic polypeptide (gip) which are increased after food intake [1-3]. |
2023-07-10 |
2023-08-14 |
Not clear |
| Alice Adriaenssens, Johannes Broichhagen, Anne de Bray, Julia Ast, Annie Hasib, Ben Jones, Alejandra Tomas, Natalie Figueredo Burgos, Orla Woodward, Jo Lewis, Elisabeth O'Flaherty, Kimberley El, Canqi Cui, Norio Harada, Nobuya Inagaki, Jonathan Campbell, Daniel Brierley, David J Hodson, Ricardo Samms, Fiona Gribble, Frank Reiman. Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding. JCI insight. vol 8. issue 10. 2023-05-22. PMID:37212283. |
these results highlight the heterogeneity of the central gipr signaling axis and suggest that studies into the effects of gip pharmacology on feeding behavior should consider the interplay of multiple regulatory pathways. |
2023-05-22 |
2023-08-14 |
Not clear |
| André Lacroi. Extensive Expertise in Endocrinology: Glucose-Dependent-Insulinotropic-Peptide (GIP)-dependent Cushing's syndrome. European journal of endocrinology. 2023-03-01. PMID:36857084. |
thirty years ago, we identified that cortisol secretion in some patients with unilateral adenoma or primary bilateral macronodular adrenal hyperplasia (pbmah) was stimulated by food intake; this was secondary to the abnormal adrenocortical responsiveness to physiological post prandial increase in glucose-dependent insulinotropic peptide (gip). |
2023-03-01 |
2023-08-14 |
Not clear |
| Miranda H J Huang, Steve Demarais, W Cooper Brookshire, Bronson K Stricklan. Analysis of supplemental wildlife feeding in Mississippi and environmental gastrointestinal parasite load. Frontiers in veterinary science. vol 9. 2022-10-13. PMID:36225801. |
supplemental feeding of deer is common among hunters and known to concentrate animals, but there is limited knowledge of how it affects gip environmental load. |
2022-10-13 |
2023-08-14 |
Not clear |
| Miranda H J Huang, Steve Demarais, W Cooper Brookshire, Bronson K Stricklan. Analysis of supplemental wildlife feeding in Mississippi and environmental gastrointestinal parasite load. Frontiers in veterinary science. vol 9. 2022-10-13. PMID:36225801. |
gip load was compared between ecologically-equivalent pairs of sites in mississippi with and without year-round supplemental feeding (average distance between pairs = 147 m). |
2022-10-13 |
2023-08-14 |
Not clear |
| Michael A Nauck, David A D'Alessi. Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction. Cardiovascular diabetology. vol 21. issue 1. 2022-09-01. PMID:36050763. |
tirzepatide is an acylated peptide engineered to activate the gip and glp-1 receptors, key mediators of insulin secretion that are also expressed in regions of the brain that regulate food intake. |
2022-09-01 |
2023-08-14 |
human |
| Zahra Hassanzadeh-Rostami, Saeed Ghobadi, Shiva Faghi. Effects of whole grain intake on glucagon-like peptide 1 and glucose-dependent insulinotropic peptide: a systematic review and meta-analysis. Nutrition reviews. 2022-08-12. PMID:35960172. |
whole grain intake may control help glycemia and reduce food intake by affecting the secretion of glucagon-like peptide 1 (glp-1) and glucose-dependent insulinotropic peptide (gip). |
2022-08-12 |
2023-08-14 |
Not clear |
| K M Pascutti, A L O'Kell, R C Hill, R A Castro, M E Salute, C Gilo. The effect of capromorelin on glycemic control in healthy dogs. Domestic animal endocrinology. vol 81. 2022-06-11. PMID:35689953. |
on d 1 of each treatment, blood glucose (bg), insulin, glucagon, glucose-dependent insulinotropic peptide (gip), and glucagon-like peptide-1 (glp-1) concentrations were measured before drug administration, then before and 30-120 min after feeding a glucose-rich diet (ensure plus, 21 kcal/kg). data were analyzed as a 2-period crossover design using generalized least squares estimation. capromorelin administration increased mean 48 h ig by10% and mean bg by 20% at 90 and 120 min post-prandially (p < 0.0001). |
2022-06-11 |
2023-08-14 |
Not clear |
| Nunzio Guccio, Fiona M Gribble, Frank Reiman. Glucose-Dependent Insulinotropic Polypeptide-A Postprandial Hormone with Unharnessed Metabolic Potential. Annual review of nutrition. 2022-05-24. PMID:35609956. |
glucose-dependent insulinotropic polypeptide (gip) is released from the upper small intestine in response to food intake and contributes to the postprandial control of nutrient disposition, including of sugars and fats. |
2022-05-24 |
2023-08-13 |
Not clear |
| Signe Stensen, Liva L Krogh, Alexander H Sparre-Ulrich, Flemming Dela, Bolette Hartmann, Tina Vilsbøll, Jens J Holst, Mette M Rosenkilde, Mikkel B Christensen, Laerke S Gasbjerg, Filip K Kno. Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity. Diabetes, obesity & metabolism. 2022-05-02. PMID:35491518. |
acute concomitant gip receptor antagonism during glp-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity. |
2022-05-02 |
2023-08-13 |
Not clear |
| Maki Takagishi, Binta Maria Aleogho, Masako Okumura, Kaori Ushida, Yuichiro Yamada, Yusuke Seino, Sayoko Fujimura, Kaoru Nakashima, Asako Shind. Nutritional control of thyroid morphogenesis through gastrointestinal hormones. Current biology : CB. 2022-02-23. PMID:35196509. |
the expression of the particular gi hormone incretin, glucose-dependent insulinotropic polypeptide (gip), responded to feeding in the intestines of xenopus tadpoles. |
2022-02-23 |
2023-08-13 |
mouse |
| Florian Kahles, Matthias Rau, Martin Reugels, Ann C Foldenauer, Robert W Mertens, Maria C Arrivas, Jörg Schröder, Paul Idel, Julia Moellmann, Emiel P C van der Vorst, Nikolaus Marx, Michael Lehrk. The gut hormone glucose-dependent insulinotropic polypeptide is downregulated in response to myocardial injury. Cardiovascular diabetology. vol 21. issue 1. 2022-02-06. PMID:35123462. |
the gut incretin hormones glp-1 (glucagon-like peptide-1) and gip (glucose-dependent insulinotropic peptide) are secreted by enteroendocrine cells following food intake leading to insulin secretion and glucose lowering. |
2022-02-06 |
2023-08-13 |
mouse |
| Maria Chiara Pelle, Michele Provenzano, Isabella Zaffina, Roberta Pujia, Federica Giofrè, Stefania Lucà, Michele Andreucci, Angela Sciacqua, Franco Artur. Role of a Dual Glucose-Dependent Insulinotropic Peptide (GIP)/Glucagon-like Peptide-1 Receptor Agonist (Twincretin) in Glycemic Control: From Pathophysiology to Treatment. Life (Basel, Switzerland). vol 12. issue 1. 2022-01-21. PMID:35054422. |
unlike glp-1, gip has little acute effect on insulin secretion and no effect on food intake; instead it seems that the gip may be an obesity-promoting hormone. |
2022-01-21 |
2023-08-13 |
Not clear |