| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Nishii, S Takashima, A Iguchi, Y Murahata, A Matsuu, Y Hikasa, H Kitagaw. Effects of sitagliptin on plasma incretin concentrations after glucose administration through an esophagostomy tube or feeding in healthy cats. Domestic animal endocrinology. vol 49. 2015-05-15. PMID:25010023. |
feeding increased both plasma glp-1 concentrations by 1.5-fold and gip concentrations by 4.6-fold. |
2015-05-15 |
2023-08-13 |
cat |
| N Nishii, S Takashima, A Iguchi, Y Murahata, A Matsuu, Y Hikasa, H Kitagaw. Effects of sitagliptin on plasma incretin concentrations after glucose administration through an esophagostomy tube or feeding in healthy cats. Domestic animal endocrinology. vol 49. 2015-05-15. PMID:25010023. |
in contrast, administration of sitagliptin did not affect plasma gip concentrations after glucose administration or feeding. |
2015-05-15 |
2023-08-13 |
cat |
| J De Toro-Martín, E Fernández-Millán, E Lizárraga-Mollinedo, E López-Oliva, P Serradas, F Escrivá, C Alvare. Predominant role of GIP in the development of a metabolic syndrome-like phenotype in female Wistar rats submitted to forced catch-up growth. Endocrinology. vol 155. issue 10. 2015-01-05. PMID:25032669. |
administration of the gip receptor antagonist (pro3)gip to uhf female rats over 21 days markedly reduced visceral fat mass and adipocyte hypertrophy without variations in food intake or body weight. |
2015-01-05 |
2023-08-13 |
rat |
| Melanie Guérard, Andreas Zeller, Matthias Festag, Christine Schubert, Thomas Singer, Lutz Mülle. Genotoxicity testing of peptides: folate deprivation as a marker of exaggerated pharmacology. Toxicology and applied pharmacology. vol 279. issue 3. 2014-11-17. PMID:24997324. |
in a bone marrow micronucleus test of a synthetic peptide (a dual agonist of the glp-1 and gip receptors) that had been integrated into a regulatory 13-week repeat-dose toxicity study in the rat, small increases in the incidence of micronuclei had been observed, together with pronounced reductions in food intake and body weight gain. |
2014-11-17 |
2023-08-13 |
rat |
| Sameer Mohammad, Rajesh T Patel, Joanne Bruno, Muhammad Siyab Panhwar, Jennifer Wen, Timothy E McGra. A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivity. Molecular and cellular biology. vol 34. issue 19. 2014-11-11. PMID:25047836. |
glucose-dependent insulinotropic polypeptide (gip), an incretin hormone secreted from gastrointestinal k cells in response to food intake, has an important role in the control of whole-body metabolism. |
2014-11-11 |
2023-08-13 |
Not clear |
| Randi Uglehold. Glucose-dependent Insulinotropic Polypeptide (GIP): From prohormone to actions in endocrine pancreas and adipose tissue. Danish medical bulletin. vol 58. issue 12. 2013-04-01. PMID:22142579. |
interest in the incretin hormone glucose-dependent insulinotropic polypeptide (gip) was reignited by the discovery that gip receptor deficient mice were unable to gain weight in response to high fat feeding. |
2013-04-01 |
2023-08-12 |
mouse |
| Randi Uglehold. Glucose-dependent Insulinotropic Polypeptide (GIP): From prohormone to actions in endocrine pancreas and adipose tissue. Danish medical bulletin. vol 58. issue 12. 2013-04-01. PMID:22142579. |
we also observed that gip receptor deficient mice could respond normally to high fat feeding with increased fat mass, but failed to increase lean mass. |
2013-04-01 |
2023-08-12 |
mouse |
| Bethany P Cummings, Andrew A Bremer, Timothy J Kieffer, David D'Alessio, Peter J Have. Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques. The Journal of endocrinology. vol 216. issue 2. 2013-03-11. PMID:23151361. |
dexamethasone-treated animals exhibited a significant increase in both insulin and glucose-dependent insulinotropic polypeptide (gip) secretion during the feeding study (p<0.05). |
2013-03-11 |
2023-08-12 |
Not clear |
| Young Min Cho, Catherine E Merchant, Timothy J Kieffe. Targeting the glucagon receptor family for diabetes and obesity therapy. Pharmacology & therapeutics. vol 135. issue 3. 2013-01-14. PMID:22659620. |
gip is rapidly released from intestinal k-cells following food intake and stimulates glucose-dependent insulin secretion from β-cells and the storage of fat in adipocytes. |
2013-01-14 |
2023-08-12 |
Not clear |
| Young Min Cho, Catherine E Merchant, Timothy J Kieffe. Targeting the glucagon receptor family for diabetes and obesity therapy. Pharmacology & therapeutics. vol 135. issue 3. 2013-01-14. PMID:22659620. |
similar to gip, glp-1 is released from intestinal l-cells following food intake and potentiates glucose-dependent insulin secretion from β-cells. |
2013-01-14 |
2023-08-12 |
Not clear |
| K R Angevine, L M Wuescher, K Andrews, L A Alexander, M F McInerney, T J Kieffer, E J Mensah-Osma. Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum. Nutrition & diabetes. vol 2. 2012-12-05. PMID:23208416. |
menin and gip are inversely regulated by food intake and diet via pi3/akt signaling in the proximal duodenum. |
2012-12-05 |
2023-08-12 |
mouse |
| K R Angevine, L M Wuescher, K Andrews, L A Alexander, M F McInerney, T J Kieffer, E J Mensah-Osma. Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum. Nutrition & diabetes. vol 2. 2012-12-05. PMID:23208416. |
in this study, we will determine the regulation of menin in the proximal duodenum by food intake and diet in correlation with gip levels in the proximal duodenum of mice after an 18 h fast followed by 4 and 7 h refeeding and 3 months of high-fat diet. |
2012-12-05 |
2023-08-12 |
mouse |
| A Ojima, T Matsui, S Maeda, M Takeuchi, S Yamagish. Glucose-dependent insulinotropic polypeptide (GIP) inhibits signaling pathways of advanced glycation end products (AGEs) in endothelial cells via its antioxidative properties. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 44. issue 7. 2012-11-06. PMID:22581648. |
glucose-dependent insulinotropic polypeptide (gip) is one of the incretins, a gut hormone secreted from k cells in the intestine in response to food intake. |
2012-11-06 |
2023-08-12 |
human |
| Nigel Irwin, Ian A Montgomery, Peter R Flat. Evaluation of the long-term effects of gastric inhibitory polypeptide-ovalbumin conjugates on insulin resistance, metabolic dysfunction, energy balance and cognition in high-fat-fed mice. The British journal of nutrition. vol 108. issue 1. 2012-10-30. PMID:22260799. |
the observed changes were almost identical in gip and (pro3)gip immunised mice and were independent of any effects on food intake or body weight. |
2012-10-30 |
2023-08-12 |
mouse |
| Steven G Chrysant, George S Chrysan. Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors. The American journal of cardiology. vol 109. issue 11. 2012-07-19. PMID:22425330. |
glp-1 and gip are secreted from the gastrointestinal tract in response to food intake. |
2012-07-19 |
2023-08-12 |
Not clear |
| S Ambati, J Duan, D L Hartzell, Y-H Choi, M A Della-Fera, C A Bail. GIP-dependent expression of hypothalamic genes. Physiological research. vol 60. issue 6. 2012-06-29. PMID:21995902. |
our objective was to investigate the role of gip in hypothalamic gene expression of biomarkers linked to regulating energy balance and feeding behavior related neurocircuitry. |
2012-06-29 |
2023-08-12 |
mouse |
| Roberta Barone Lumaga, Danilo Azzali, Vincenzo Fogliano, Luca Scalfi, Paola Vitaglion. Sugar and dietary fibre composition influence, by different hormonal response, the satiating capacity of a fruit-based and a β-glucan-enriched beverage. Food & function. vol 3. issue 1. 2012-04-16. PMID:22057424. |
appetite ratings over 3 h post-breakfast and energy intakes at ad libitum lunch, blood glucose, insulin, ghrelin, pyy, glp-1, gip, and pp concentrations, and 24 h food intake, were assessed. |
2012-04-16 |
2023-08-12 |
human |
| Sameer Mohammad, Lavoisier S Ramos, Jochen Buck, Lonny R Levin, Francesco Rubino, Timothy E McGra. Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase. The Journal of biological chemistry. vol 286. issue 50. 2012-03-27. PMID:22027830. |
gastric inhibitory peptide (gip) is an incretin hormone secreted in response to food intake. |
2012-03-27 |
2023-08-12 |
Not clear |
| Ryuzo Kawamor. [The concept of incretins and the physiological roles of incretins]. Nihon rinsho. Japanese journal of clinical medicine. vol 69. issue 5. 2011-07-08. PMID:21595259. |
glp-1, but not gip, controls glycemia via additional actions on glucose sensors, inhibition of gastric emptying, food intake and glucagon secretion. |
2011-07-08 |
2023-08-12 |
Not clear |
| N Irwin, J M E Francis, P R Flat. Alterations of glucose-dependent insulinotropic polypeptide (GIP) during cold acclimation. Regulatory peptides. vol 167. issue 1. 2011-06-29. PMID:21146561. |
by the end of the study, cold acclimated rats had significantly (p<0.01) increased bat mass and intestinal concentrations of gip and glp-1 compared to controls, independent of food intake. |
2011-06-29 |
2023-08-12 |
rat |