| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I S Ebeneze. Effects of buspirone on operant and nonoperant food intake in food deprived rats. Methods and findings in experimental and clinical pharmacology. vol 18. issue 7. 1997-03-07. PMID:8900221. |
buspirone (0.5-2.0 mg/kg), administered subcutaneously (s.c.) 15 min prior to presentation of food, produced a dose-related inhibition of food intake in the nonoperant feeding paradigm. |
1997-03-07 |
2023-08-12 |
rat |
| I S Ebeneze. Effects of buspirone on operant and nonoperant food intake in food deprived rats. Methods and findings in experimental and clinical pharmacology. vol 18. issue 7. 1997-03-07. PMID:8900221. |
likewise, in the operant feeding paradigm, buspirone (0.25-1.0 mg/kg, s.c.) produced a dose-related suppression of food intake in the first 30 min after administration. |
1997-03-07 |
2023-08-12 |
rat |
| I S Ebeneze. Effects of buspirone on operant and nonoperant food intake in food deprived rats. Methods and findings in experimental and clinical pharmacology. vol 18. issue 7. 1997-03-07. PMID:8900221. |
the results of the study, therefore, suggest that the inhibitory effects of buspirone on food intake in food-deprived rats are unlikely to be due to nonspecific disruptions of behavior. |
1997-03-07 |
2023-08-12 |
rat |
| I S Ebenezer, J Brooma. Pretreatment with the 5-HT1A receptor agonists 8-OH-DPAT or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (CCK) on food intake in rats. Methods and findings in experimental and clinical pharmacology. vol 16. issue 8. 1995-06-26. PMID:7760584. |
pretreatment with the 5-ht1a receptor agonists 8-oh-dpat or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (cck) on food intake in rats. |
1995-06-26 |
2023-08-12 |
rat |
| I S Ebenezer, J Brooma. Pretreatment with the 5-HT1A receptor agonists 8-OH-DPAT or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (CCK) on food intake in rats. Methods and findings in experimental and clinical pharmacology. vol 16. issue 8. 1995-06-26. PMID:7760584. |
in order to investigate whether the inhibitory effect of systemically administered cholecystokinin (cck) on food intake is dependent on an interaction with central 5-hydroxytryptamine (5-ht) processes, we examined the effects of pretreating rats that were deprived of food for various periods of time (22 h in experiments 1 and 3, 3 h in experiment 2, and 1 h in experiment 4) with the 5-ht1a receptor agonists, 8-oh-dpat or gepirone, on the suppression of feeding induced by intraperitoneal cck. |
1995-06-26 |
2023-08-12 |
rat |
| I S Ebenezer, J Brooma. Pretreatment with the 5-HT1A receptor agonists 8-OH-DPAT or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (CCK) on food intake in rats. Methods and findings in experimental and clinical pharmacology. vol 16. issue 8. 1995-06-26. PMID:7760584. |
8-oh-dpat (100 micrograms/kg, experiments 1 and 2) or gepirone (2 mg/kg, experiments 3 and 4) administered subcutaneously 60 min prior to intraperitoneal injection of cck (6 micrograms/kg) did not attenuate the suppressant effect of cck on feeding in any of these experiments. |
1995-06-26 |
2023-08-12 |
rat |
| I S Ebenezer, J Brooma. Pretreatment with the 5-HT1A receptor agonists 8-OH-DPAT or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (CCK) on food intake in rats. Methods and findings in experimental and clinical pharmacology. vol 16. issue 8. 1995-06-26. PMID:7760584. |
as it has been established that the doses of 8-oh-dpat and gepirone used in this study decrease 5-ht function in the central nervous system, the present results indicate that it is unlikely that the inhibitory effect of systemically administered cck on food intake is dependent on an interaction with intact central 5-ht systems. |
1995-06-26 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
sex difference in the feeding responses of non-deprived rats to the 5-ht1a agonists 8-oh-dpat and gepirone. |
1994-07-21 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
the aim of this study was to determine whether there was any difference in the feeding responses of male and female rats to the 5-ht1a agonists 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat) and gepirone. |
1994-07-21 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
similar doses of 8-oh-dpat and gepirone had no effects on food intake in non-deprived female rats. |
1994-07-21 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
however, a higher dose of gepirone (i.e., 8 mg/kg, s.c.) significantly increased feeding (p < 0.01) in non-deprived female rats. |
1994-07-21 |
2023-08-12 |
rat |
| C A Sannerud, N A Ator, R R Griffith. Behavioral pharmacology of tandospirone in baboons: chronic administration and withdrawal, self-injection and drug discrimination. Drug and alcohol dependence. vol 32. issue 3. 1993-09-16. PMID:8102330. |
substitution of vehicle for tandospirone after 7 weeks produced time-limited suppression of food intake, suggesting a mild withdrawal syndrome. |
1993-09-16 |
2023-08-12 |
Not clear |
| E T Li, S Lu. Buspirone-induced carbohydrate feeding is not influenced by route of administration and nutritional status. Brain research bulletin. vol 30. issue 5-6. 1993-04-26. PMID:8457904. |
regardless of route of administration, buspirone increased food intake over the first 2 h of food presentation in a dose-dependent manner. |
1993-04-26 |
2023-08-12 |
rat |
| P J Fletcher, M H Zack, D V Coscin. Influence of taste and food texture on the feeding responses induced by 8-OH-DPAT and gepirone. Psychopharmacology. vol 104. issue 3. 1991-11-18. PMID:1681556. |
influence of taste and food texture on the feeding responses induced by 8-oh-dpat and gepirone. |
1991-11-18 |
2023-08-11 |
rat |
| P J Fletcher, M H Zack, D V Coscin. Influence of taste and food texture on the feeding responses induced by 8-OH-DPAT and gepirone. Psychopharmacology. vol 104. issue 3. 1991-11-18. PMID:1681556. |
previously it has been shown that 5-hydroxy-tryptamine (5-ht)1a agonists such as 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) and gepirone increase food intake in free-feeding rats. |
1991-11-18 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. Effects of 8-OH-DPAT, buspirone and ICS 205-930 on feeding in a novel environment: comparisons with chlordiazepoxide and FG 7142. Psychopharmacology. vol 102. issue 3. 1991-01-17. PMID:2147516. |
effects of 8-oh-dpat, buspirone and ics 205-930 on feeding in a novel environment: comparisons with chlordiazepoxide and fg 7142. |
1991-01-17 |
2023-08-11 |
Not clear |
| P J Fletcher, M Davie. Effects of 8-OH-DPAT, buspirone and ICS 205-930 on feeding in a novel environment: comparisons with chlordiazepoxide and FG 7142. Psychopharmacology. vol 102. issue 3. 1991-01-17. PMID:2147516. |
it is suggested that the tendency of buspirone and 8-oh-dpat to suppress exploratory activity may thus result in enhanced feeding duration. |
1991-01-17 |
2023-08-11 |
Not clear |
| S Q Luo, T Ransom, E T L. Selective increase in carbohydrate intake by rats treated with 8-hydroxy-2-(di-n-propylamino)-tetraline or buspirone. Life sciences. vol 46. issue 23. 1990-07-23. PMID:2141379. |
both 8-hydroxy-2-(di-n-propylamino)-tetraline (8-oh-dpat) and buspirone (busp) were found to induce food intake in free-feeding, self-selecting young rats. |
1990-07-23 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone. British journal of pharmacology. vol 99. issue 3. 1990-06-06. PMID:2139586. |
the roles of 5-hydroxytryptamine (5-ht) and dopamine systems in mediating the increased feeding induced by buspirone, gepirone and ipsapirone were investigated. |
1990-06-06 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone. British journal of pharmacology. vol 99. issue 3. 1990-06-06. PMID:2139586. |
thus buspirone does not appear to interact with 5-ht systems to elicit feeding. |
1990-06-06 |
2023-08-11 |
rat |