| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nandakumar S Narayanan, Benjamin B Land, John E Solder, Karl Deisseroth, Ralph J DiLeon. Prefrontal D1 dopamine signaling is required for temporal control. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 50. 2013-02-28. PMID:23185016. |
the medial prefrontal cortex controls many goal-directed behaviors and receives dopaminergic input primarily from the midbrain ventral tegmental area. |
2013-02-28 |
2023-08-12 |
Not clear |
| Anthony J Gifuni, Solmaz Jozaghi, Anne-Catherine Gauthier-Lamer, Sandra M Boy. Lesions of the lateral habenula dissociate the reward-enhancing and locomotor-stimulant effects of amphetamine. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842070. |
midbrain dopamine neurons play a key role in goal-directed behaviour as well as in some psychiatric disorders. |
2013-01-10 |
2023-08-12 |
rat |
| H Ohira, M Matsunaga, K Kimura, H Murakami, T Osumi, T Isowa, S Fukuyama, J Shinoda, J Yamad. Chronic stress modulates neural and cardiovascular responses during reversal learning. Neuroscience. vol 193. 2012-01-18. PMID:21763760. |
during the reversal learning task, whereas participants with low chronic job stress exhibited activity in the anterior caudate, as well as orbitofrontal cortex, ventrolateral prefrontal cortex, insula, and midbrain, which might be related to the goal-directed action, participants with high chronic job stress exhibited no activity in such brain regions. |
2012-01-18 |
2023-08-12 |
human |
| Mehdi Keramati, Amir Dezfouli, Payam Pira. Speed/accuracy trade-off between the habitual and the goal-directed processes. PLoS computational biology. vol 7. issue 5. 2011-09-27. PMID:21637741. |
neurobiologically, by assuming that phasic and tonic activities of midbrain dopamine neurons carry the reward prediction error and the average reward signals used by the model, respectively, the model predicts that whereas phasic dopamine indirectly affects behaviour through reinforcing stimulus-response associations, tonic dopamine can directly affect behaviour through manipulating the competition between the habitual and the goal-directed systems and thus, affect reaction time. |
2011-09-27 |
2023-08-12 |
Not clear |
| Thomas F Münte, Marcus Heldmann, Hermann Hinrichs, Josep Marco-Pallares, Ulrike M Krämer, Volker Sturm, Hans-Jochen Heinz. Nucleus Accumbens is Involved in Human Action Monitoring: Evidence from Invasive Electrophysiological Recordings. Frontiers in human neuroscience. vol 1. 2011-07-14. PMID:18958225. |
importantly, cross-correlation analysis showed that error-related activity in the nacc preceded surface activity by 40 ms. we propose that the nacc is involved in action monitoring, possibly by using error signals from the dopaminergic midbrain to adjust the relative impact of limbic and prefrontal inputs on frontal control systems in order to optimize goal-directed behavior. |
2011-07-14 |
2023-08-12 |
human |
| Mark T Harnett, Brian E Bernier, Kee-Chan Ahn, Hitoshi Morikaw. Burst-timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons. Neuron. vol 62. issue 6. 2009-07-09. PMID:19555651. |
bursts of spikes triggered by sensory stimuli in midbrain dopamine neurons evoke phasic release of dopamine in target brain areas, driving reward-based reinforcement learning and goal-directed behavior. |
2009-07-09 |
2023-08-12 |
Not clear |
| Yael Niv, Geoffrey Schoenbau. Dialogues on prediction errors. Trends in cognitive sciences. vol 12. issue 7. 2008-09-30. PMID:18567531. |
neural correlates of such prediction-error signals have been observed now in midbrain dopaminergic neurons, striatum, amygdala and even prefrontal cortex, and models incorporating prediction errors have been invoked to explain complex phenomena such as the transition from goal-directed to habitual behavior. |
2008-09-30 |
2023-08-12 |
Not clear |
| Michele Migliore, Claudio Cannia, Carmen C Canavie. A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling. Journal of neurophysiology. vol 99. issue 5. 2008-07-22. PMID:18353916. |
midbrain dopaminergic neurons are involved in several critical brain functions controlling goal-directed behaviors, reinforcing/reward processes, and motivation. |
2008-07-22 |
2023-08-12 |
Not clear |
| Marie Vandecasteele, Jacques Glowinski, Jean-Michel Deniau, Laurent Venanc. Chemical transmission between dopaminergic neuron pairs. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 12. 2008-04-22. PMID:18347345. |
midbrain dopaminergic (daergic) neurons play a major regulatory role in in goal-directed behavior and reinforcement learning. |
2008-04-22 |
2023-08-12 |
rat |
| Paul J Kruzich, David K Grand. Dopamine D2 receptors mediate two-odor discrimination and reversal learning in C57BL/6 mice. BMC neuroscience. vol 5. 2004-05-06. PMID:15061865. |
dopamine modulation of neuronal signaling in the frontal cortex, midbrain, and striatum is essential for processing and integrating diverse external sensory stimuli and attaching salience to environmental cues that signal causal relationships, thereby guiding goal-directed, adaptable behaviors. |
2004-05-06 |
2023-08-12 |
mouse |
| M Vidailhet, C P Jedynak, P Pollak, Y Agi. Pathology of symptomatic tremors. Movement disorders : official journal of the Movement Disorder Society. vol 13 Suppl 3. 1999-03-22. PMID:9827595. |
symptomatic tremors are labeled in the literature under different names including rubral tremor, midbrain tremor, thalamic tremor, myorhythmia, holmes' tremor, cerebellar tremor, and goal-directed tremor. |
1999-03-22 |
2023-08-12 |
Not clear |
| J Mirenowicz, W Schult. Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli. Nature. vol 379. issue 6564. 1996-02-27. PMID:8559249. |
midbrain dopamine systems are crucially involved in motivational processes underlying the learning and execution of goal-directed behaviour. |
1996-02-27 |
2023-08-12 |
monkey |