| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy Hennigan, Charlotte K Callaghan, John Kealy, Jennifer Rouine, Aine M Kell. Deficits in LTP and recognition memory in the genetically hypertensive rat are associated with decreased expression of neurotrophic factors and their receptors in the dentate gyrus. Behavioural brain research. vol 197. issue 2. 2009-02-23. PMID:18957307. |
we conclude that the impairments in ltp and learning and memory observed in the gh strain are associated with aberrant expression of specific neurotrophic factors and their receptors in the dentate gyrus, adding weight to the evidence indicating a role for these proteins in several forms of synaptic plasticity. |
2009-02-23 |
2023-08-12 |
rat |
| D Ribes, M T Colomina, P Vicens, J L Doming. Effects of oral aluminum exposure on behavior and neurogenesis in a transgenic mouse model of Alzheimer's disease. Experimental neurology. vol 214. issue 2. 2009-01-07. PMID:18834880. |
aluminum exposure impaired learning and memory in wild mice and increased the total number of proliferating cells in the dentate gyrus of hippocampus. |
2009-01-07 |
2023-08-12 |
mouse |
| José J Rodríguez, Victoria C Jones, Masashi Tabuchi, Stuart M Allan, Elysse M Knight, Frank M LaFerla, Salvatore Oddo, Alexei Verkhratsk. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PloS one. vol 3. issue 8. 2008-12-18. PMID:18698410. |
it has become generally accepted that new neurones are added and integrated mainly in two areas of the mammalian cns, the subventricular zone and the subgranular zone (sgz) of the dentate gyrus (dg) of the hippocampus, which is of central importance in learning and memory. |
2008-12-18 |
2023-08-12 |
mouse |
| Luis G Rabaneda, Manuel Carrasco, Miguel A López-Toledano, Maribel Murillo-Carretero, Félix A Ruiz, Carmen Estrada, Carmen Castr. Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 22. issue 11. 2008-11-18. PMID:18703672. |
this inhibition occurs in the caudal areas of the dentate gyrus (dg) of the hippocampus, a neurogenic area mainly involved in learning and memory performance, and in the svz, recently implicated in olfactory learning performance. |
2008-11-18 |
2023-08-12 |
mouse |
| Stefano Farioli-Vecchioli, Daniele Saraulli, Marco Costanzi, Simone Pacioni, Irene Cinà, Massimiliano Aceti, Laura Micheli, Alberto Bacci, Vincenzo Cestari, Felice Tiron. The timing of differentiation of adult hippocampal neurons is crucial for spatial memory. PLoS biology. vol 6. issue 10. 2008-11-17. PMID:18842068. |
functionally, this genetic manipulation specifically affected different hippocampus-dependent learning and memory tasks, including contextual fear conditioning, and selectively reduced synaptic plasticity in the dentate gyrus. |
2008-11-17 |
2023-08-12 |
mouse |
| Christophe Galichet, François Guillemot, Carlos M Parra. Neurogenin 2 has an essential role in development of the dentate gyrus. Development (Cambridge, England). vol 135. issue 11. 2008-09-26. PMID:18448566. |
the dentate gyrus (dg) of the hippocampus has a central role in learning and memory in adult rodents. |
2008-09-26 |
2023-08-12 |
mouse |
| Henriette van Praa. Neurogenesis and exercise: past and future directions. Neuromolecular medicine. vol 10. issue 2. 2008-09-19. PMID:18286389. |
physical activity also causes a robust increase in neurogenesis in the dentate gyrus of the hippocampus, a brain area important for learning and memory. |
2008-09-19 |
2023-08-12 |
Not clear |
| Rona Baron, Anna Nemirovsky, Idan Harpaz, Hagit Cohen, Trevor Owens, Alon Monsoneg. IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 22. issue 8. 2008-09-03. PMID:18390924. |
we demonstrate that in contrast to primarily innate immunity cytokines, such as interleukin-6 and tumor necrosis factor-alpha, the adaptive immunity cytokine ifn-gamma enhances neurogenesis in the dentate gyrus of adult mice and improves the spatial learning and memory performance of the animals. |
2008-09-03 |
2023-08-12 |
mouse |
| Nishi Srivastava, Kavita Seth, Nalini Srivastava, Vinay K Khanna, Ashok Kumar Agrawa. Functional restoration using basic fibroblast growth factor (bFGF) infusion in Kainic acid induced cognitive dysfunction in rat: neurobehavioural and neurochemical studies. Neurochemical research. vol 33. issue 7. 2008-08-20. PMID:17955369. |
four-weeks post lesioning rats were assessed for impairment in learning and memory using y maze followed by bfgf infusion in dentate gyrus region. |
2008-08-20 |
2023-08-12 |
rat |
| Brenda E Porte. Neurogenesis and epilepsy in the developing brain. Epilepsia. vol 49 Suppl 5. 2008-08-04. PMID:18522600. |
future studies need to focus on how these changes in neurogenesis influence dentate gyrus function and what they imply for epileptogenesis and learning and memory impairments, so commonly found in children with temporal lobe epilepsy. |
2008-08-04 |
2023-08-12 |
Not clear |
| Siamak Shahidi, Alireza Komaki, Minoo Mahmoodi, Reza Lashgar. The role of GABAergic transmission in the dentate gyrus on acquisition, consolidation and retrieval of an inhibitory avoidance learning and memory task in the rat. Brain research. vol 1204. 2008-07-22. PMID:18331724. |
the role of gabaergic transmission in the dentate gyrus on acquisition, consolidation and retrieval of an inhibitory avoidance learning and memory task in the rat. |
2008-07-22 |
2023-08-12 |
rat |
| Siamak Shahidi, Alireza Komaki, Minoo Mahmoodi, Reza Lashgar. The role of GABAergic transmission in the dentate gyrus on acquisition, consolidation and retrieval of an inhibitory avoidance learning and memory task in the rat. Brain research. vol 1204. 2008-07-22. PMID:18331724. |
the aim of this study is to define the function of gabaergic synaptic transmission in the dentate gyrus (dg) of the hippocampus in the different stages of inhibitory avoidance (ia) learning and memory in the rat. |
2008-07-22 |
2023-08-12 |
rat |
| Anandh Dhanushkodi, Ashok K Shett. Is exposure to enriched environment beneficial for functional post-lesional recovery in temporal lobe epilepsy? Neuroscience and biobehavioral reviews. vol 32. issue 4. 2008-06-20. PMID:18178250. |
exposure to enriched environment has been shown to induce robust neuronal plasticity in both intact and injured adult central nervous system, including up-regulation of multiple neurotrophic factors, enhanced neurogenesis in the dentate gyrus of the hippocampus, and improved spatial learning and memory function. |
2008-06-20 |
2023-08-12 |
rat |
| J Harry Blaise, Jessica L Koranda, Urey Chow, Kaitlin E Haines, Emily C Dorwar. Neonatal isolation stress alters bidirectional long-term synaptic plasticity in amygdalo-hippocampal synapses in freely behaving adult rats. Brain research. vol 1193. 2008-06-03. PMID:18178177. |
the basolateral amygdala (bla) is known to be involved in emotional and stress responses, while the dentate gyrus (dg), a subfield of the hippocampus, is implicated in learning and memory. |
2008-06-03 |
2023-08-12 |
rat |
| Raymond P Kesne. A behavioral analysis of dentate gyrus function. Progress in brain research. vol 163. 2008-03-14. PMID:17765738. |
computational models of the dentate gyrus (dg) have suggested based on anatomical, electrophysiological, and computer simulation data that the dg plays an important role in learning and memory by processing and representing spatial information on the basis of conjunctive encoding, pattern separation, and encoding of spatial information in conjunction with the ca3. |
2008-03-14 |
2023-08-12 |
Not clear |
| Bin Li, Hidenaga Yamamori, Yoshitaka Tatebayashi, Bridget Shafit-Zagardo, Hitoshi Tanimukai, She Chen, Khalid Iqbal, Inge Grundke-Iqba. Failure of neuronal maturation in Alzheimer disease dentate gyrus. Journal of neuropathology and experimental neurology. vol 67. issue 1. 2008-03-05. PMID:18091557. |
neurogenesis in the dentate gyrus is thought to play an important role in hippocampus-dependent learning and memory. |
2008-03-05 |
2023-08-12 |
Not clear |
| J E Cohen, G Zimmerman, N Melamed-Book, A Friedman, A Dori, H Sore. Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells. Hippocampus. vol 18. issue 2. 2008-03-03. PMID:17960645. |
in the adult murine hippocampus, dentate gyrus (dg), neurogenesis and neural cell death are thought to affect learning and memory in incompletely understood mechanism(s). |
2008-03-03 |
2023-08-12 |
mouse |
| Michael J Chumley, Timothy Catchpole, Robert E Silvany, Steven G Kernie, Mark Henkemeye. EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 49. 2007-12-27. PMID:18057206. |
one of these, the subgranular zone of the hippocampal dentate gyrus, is of primary interest because of the role of this region in learning and memory. |
2007-12-27 |
2023-08-12 |
mouse |
| Jorge J Palop, Jeannie Chin, Erik D Roberson, Jun Wang, Myo T Thwin, Nga Bien-Ly, Jong Yoo, Kaitlyn O Ho, Gui-Qiu Yu, Anatol Kreitzer, Steven Finkbeiner, Jeffrey L Noebels, Lennart Muck. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. vol 55. issue 5. 2007-11-01. PMID:17785178. |
happ mice with high levels of amyloid-beta peptides in the brain develop ad-like abnormalities, including cognitive deficits and depletions of calcium-related proteins in the dentate gyrus, a region critically involved in learning and memory. |
2007-11-01 |
2023-08-12 |
mouse |
| Helen E Scharfman, William P Gra. Relevance of seizure-induced neurogenesis in animal models of epilepsy to the etiology of temporal lobe epilepsy. Epilepsia. vol 48 Suppl 2. 2007-07-17. PMID:17571351. |
although initial studies predicted that neurogenesis in the dentate gyrus would be important to normal functions, such as learning and memory, the new neurons that are born after seizures may not necessarily promote normal function. |
2007-07-17 |
2023-08-12 |
Not clear |