| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ayumu Tashiro, Hiroshi Makino, Fred H Gag. Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 12. 2007-04-12. PMID:17376985. |
this experience-specific functional modification through adult neurogenesis could be a mechanism by which new neurons exert a long-term influence on the function of the dentate gyrus related to learning and memory. |
2007-04-12 |
2023-08-12 |
Not clear |
| Charles Scerri, Caroline A Stewart, Kieran C Breen, David J K Balfou. The effects of chronic nicotine on spatial learning and bromodeoxyuridine incorporation into the dentate gyrus of the rat. Psychopharmacology. vol 184. issue 3-4. 2006-10-06. PMID:16025316. |
improved learning and memory has also been related to increased neurogenesis in the dentate gyrus (dg) of the hippocampal formation. |
2006-10-06 |
2023-08-12 |
rat |
| Reza Lashgari, Fereshteh Motamedi, Saleh Zahedi Asl, Siamak Shahidi, Alireza Komak. Behavioral and electrophysiological studies of chronic oral administration of L-type calcium channel blocker verapamil on learning and memory in rats. Behavioural brain research. vol 171. issue 2. 2006-09-25. PMID:16707172. |
in this study, the effect of chronic (60 days) oral administration of l-type calcium channel blocker verapamil on learning and memory and synaptic plasticity of hippocampal dentate gyrus in rats has been investigated. |
2006-09-25 |
2023-08-12 |
rat |
| B W Scott, W M Burnha. Kindled seizures enhance young neuron survival in the adult rat dentate gyrus. Acta neuropathologica. vol 111. issue 4. 2006-08-24. PMID:16520968. |
these results demonstrate that kindled seizures enhance the survival of new born neurons in the adult rat dentate gyrus which may reflect the actions of an activity-dependent mechanism normally involved in hippocampal-dependent learning and memory. |
2006-08-24 |
2023-08-12 |
rat |
| Myung Sook Oh, Chan Park, Youngbuhm Huh, Hong-Yeoul Kim, Hocheol Kim, Hyung-Min Kim, Hyunsu Bae, Duk Kyun Ahn, Wan-Su Park, Seong Kyu Par. The effects of BR003 on memory and cell proliferation in the dentate gyrus of rat hippocampus. Biological & pharmaceutical bulletin. vol 29. issue 4. 2006-05-24. PMID:16595925. |
we investigated the effects of oral administration of br003 to wistar rats on (a) learning and memory using a passive avoidance test and (b) cell proliferation in the dentate gyrus (dg) of the hippocampus using immunohistochemical analysis of 5-bromo-2-deoxyuridine (brdu) expression. |
2006-05-24 |
2023-08-12 |
rat |
| Benedetta Leuner, Elizabeth Gould, Tracey J Shor. Is there a link between adult neurogenesis and learning? Hippocampus. vol 16. issue 3. 2006-05-04. PMID:16421862. |
this review discusses both sides of this issue, considering the effects of learning on the production of new neurons in the dentate gyrus and the question of whether newly born cells participate in learning and memory. |
2006-05-04 |
2023-08-12 |
Not clear |
| Yaniv Ziv, Noga Ron, Oleg Butovsky, Gennady Landa, Einav Sudai, Nadav Greenberg, Hagit Cohen, Jonathan Kipnis, Michal Schwart. Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nature neuroscience. vol 9. issue 2. 2006-03-29. PMID:16415867. |
cns-specific t cells were also found to be required for spatial learning and memory and for the expression of brain-derived neurotrophic factor in the dentate gyrus, implying that a common immune-associated mechanism underlies different aspects of hippocampal plasticity and cell renewal in the adult brain. |
2006-03-29 |
2023-08-12 |
mouse |
| Bharathi Hattiangady, Muddanna S Rao, Geetha A Shetty, Ashok K Shett. Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus. Experimental neurology. vol 195. issue 2. 2005-11-21. PMID:16002067. |
we analyzed three proteins that are well-known to promote dentate neurogenesis and learning and memory function in the dentate gyrus and the hippocampal ca1 and ca3 subfields of young, middle-aged and aged f344 rats. |
2005-11-21 |
2023-08-12 |
rat |
| Myung Sook Oh, Youngbuhm Huh, Hyunsu Bae, Duk Kyun Ahn, Seong Kyu Par. The multi-herbal formula Guibi-tang enhances memory and increases cell proliferation in the rat hippocampus. Neuroscience letters. vol 379. issue 3. 2005-06-24. PMID:15843064. |
these results suggest that administration of gbt to rats not only improves learning and memory but also increases the proliferation of cells in the dentate gyrus of the hippocampus. |
2005-06-24 |
2023-08-12 |
rat |
| Owain W Howell, Kharen Doyle, Jeffrey H Goodman, Helen E Scharfman, Herbert Herzog, Ashley Pringle, Annette G Beck-Sickinger, William P Gra. Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus. Journal of neurochemistry. vol 93. issue 3. 2005-06-03. PMID:15836615. |
neuropeptide y (npy), a peptide neurotransmitter released by interneurons in the dentate gyrus, has important effects on mood, anxiety-related behaviour and learning and memory. |
2005-06-03 |
2023-08-12 |
mouse |
| Kendra N Shaw, Sean Commins, Shane M O'Mar. Cyclooxygenase inhibition attenuates endotoxin-induced spatial learning deficits, but not an endotoxin-induced blockade of long-term potentiation. Brain research. vol 1038. issue 2. 2005-05-24. PMID:15757639. |
we also show that lps causes an impairment in the induction of long-term potentiation in the dentate gyrus in vivo, a major contemporary model of learning and memory. |
2005-05-24 |
2023-08-12 |
Not clear |
| Cigdem Akman, Qian Zhao, Xianzeng Liu, Gregory L Holme. Effect of food deprivation during early development on cognition and neurogenesis in the rat. Epilepsy & behavior : E&B. vol 5. issue 4. 2004-09-21. PMID:15256180. |
to evaluate the effects of food deprivation on brain development, we evaluated visual-spatial learning and memory and neurogenesis in the dentate gyrus of the hippocampus in food-deprived (fd) and well-fed (wf) rats. |
2004-09-21 |
2023-08-12 |
rat |
| Matthias Kohn, Peter Steinbach, Horst Hameister, Hildegard Kehrer-Sawatzk. A comparative expression analysis of four MRX genes regulating intracellular signalling via small GTPases. European journal of human genetics : EJHG. vol 12. issue 1. 2004-05-06. PMID:14673471. |
we noticed the highest expression of these genes in the dentate gyrus and cornu ammonis of the hippocampus, in structures engaged in learning and memory. |
2004-05-06 |
2023-08-12 |
mouse |
| Katja Naie, Denise Manahan-Vaugha. Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 2. 2004-03-19. PMID:14704216. |
regulation by metabotropic glutamate receptor 5 of ltp in the dentate gyrus of freely moving rats: relevance for learning and memory formation. |
2004-03-19 |
2023-08-12 |
rat |
| Takatoshi Ueki, Masamitsu Tanaka, Kanna Yamashita, Sumiko Mikawa, ZheFu Qiu, Nicholas J Maragakis, Robert F Hevner, Naoyuki Miura, Haruhiko Sugimura, Kohji Sat. A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684875. |
neurogenesis occurs in restricted regions in the adult mammalian brain, among which the neurogenesis in the hippocampal dentate gyrus plays the crucial role in learning and memory. |
2004-01-16 |
2023-08-12 |
Not clear |
| Choon-Gon Jang, Seok-Yong Lee, Ji-Hoon Yoo, Ji-Jing Yan, Dong-Keun Song, Horace H Loh, Ing K H. Impaired water maze learning performance in mu-opioid receptor knockout mice. Brain research. Molecular brain research. vol 117. issue 1. 2003-12-01. PMID:14499482. |
previous study has demonstrated that the lack of mu-opioid receptor decreased ltp in the dentate gyrus of the hippocampus, suggesting the possibility that the lack of mu-opioid receptor may accompany a change in learning and memory. |
2003-12-01 |
2023-08-12 |
mouse |
| Jorge J Palop, Brian Jones, Lisa Kekonius, Jeannie Chin, Gui-Qiu Yu, Jacob Raber, Eliezer Masliah, Lennart Muck. Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 16. 2003-10-03. PMID:12881482. |
learning deficits in mice expressing familial ad-mutant happ correlated strongly with decreased levels of the calcium-binding protein calbindin-d28k (cb) and the calcium-dependent immediate early gene product c-fos in granule cells of the dentate gyrus, a brain region critically involved in learning and memory. |
2003-10-03 |
2023-08-12 |
mouse |
| Christian Gianinazzi, Denis Grandgirard, Hans Imboden, Lotti Egger, Damian N Meli, Yoeng-Delphine Bifrare, Philipp C Joss, Martin G Täuber, Christoph Borner, Stephen L Lei. Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica. vol 105. issue 5. 2003-06-06. PMID:12677451. |
bacterial meningitis causes neuronal apoptosis in the hippocampal dentate gyrus, which is associated with learning and memory impairments after cured disease. |
2003-06-06 |
2023-08-12 |
rat |
| Frantz Rom Poulsen, Morten Meyer, Jens Zimmer Rasmusse. [Generation of new nerve cells in the adult human brain]. Ugeskrift for laeger. vol 165. issue 14. 2003-06-02. PMID:12715673. |
in the dentate gyrus the newly generated neurons become functionally integrated in the granule cell layer, where they are believed to be of importance to learning and memory. |
2003-06-02 |
2023-08-12 |
human |
| B Truchet, F A Chaillan, B Soumireu-Mourat, F S Roma. Learning and memory of cue-reward association meaning by modifications of synaptic efficacy in dentate gyrus and piriform cortex. Hippocampus. vol 12. issue 5. 2003-01-21. PMID:12440576. |
learning and memory of cue-reward association meaning by modifications of synaptic efficacy in dentate gyrus and piriform cortex. |
2003-01-21 |
2023-08-12 |
rat |