| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alex Steiner, Benjamin M Owen, James P Bauer, Leann Seanez, Sam Kwon, Jessica E Biddinger, Ragan Huffman, Julio E Ayala, William P Nobis, Alan S Lewi. Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis. Hippocampus. 2022-09-05. PMID:36063105. |
understanding the role of dentate gyrus (dg) mossy cells (mcs) in learning and memory has rapidly evolved due to increasingly precise methods for targeting mcs and for in vivo recording and activity manipulation in rodents. |
2022-09-05 |
2023-08-14 |
mouse |
| Yuan-Hung Lin King, Chao Chen, John V Lin King, Jeffrey Simms, Edward Glasscock, Shi-Bing Yang, Yuh-Nung Jan, Lily Y Ja. K Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 22. 2022-07-16. PMID:35613055. |
we determined that kv1.1 deletion in adult neural stem cells causes overproliferation and depletion of radial glia-like neural stem cells, prevents proper adult-born granule cell maturation and integration into the dentate gyrus, and moderately impairs hippocampus-dependent contextual fear learning and memory. |
2022-07-16 |
2023-08-16 |
mouse |
| Peng Ren, Bin Xiao, Lin-Ping Wang, Ying-Shun Li, Hua Jin, Qing-Hua Ji. Nitric oxide impairs spatial learning and memory in a rat model of Alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. Behavioural brain research. 2022-01-16. PMID:35033612. |
nitric oxide impairs spatial learning and memory in a rat model of alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. |
2022-01-16 |
2023-08-13 |
rat |
| Peng Ren, Bin Xiao, Lin-Ping Wang, Ying-Shun Li, Hua Jin, Qing-Hua Ji. Nitric oxide impairs spatial learning and memory in a rat model of Alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. Behavioural brain research. 2022-01-16. PMID:35033612. |
however, whether no in the hippocampal dentate gyrus (dg) is involved in the spatial learning and memory impairments of ad by affecting the glutamate (glu) response during these processes is not well-understood. |
2022-01-16 |
2023-08-13 |
rat |
| Brenna Hourigan, Spencer D Balay, Graydon Yee, Saloni Sharma, Qiumin Ta. Capicua regulates the development of adult-born neurons in the hippocampus. Scientific reports. vol 11. issue 1. 2021-11-26. PMID:34083623. |
new neurons continuously arise from neural progenitor cells in the dentate gyrus of the adult hippocampus to support ongoing learning and memory formation. |
2021-11-26 |
2023-08-13 |
mouse |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
the role of norepinephrine of the hippocampal dentate gyrus in spatial learning and memory alteration induced by chronic restraint stress (crs, 3 h/day, 6 weeks) was investigated in aged rats. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
spatial learning and memory were assessed by the morris water maze (mwm), and the extracellular concentration of norepinephrine and amplitude of field excitatory postsynaptic potential (fepsp) were measured in the dentate gyrus during mwm test in freely-moving rats. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
next, the involvement of β-adrenoceptors in spatial learning and memory of crs rats was examined by microinjection of its antagonist (propranolol) into the dentate gyrus. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
compared with the control group, the basal level of norepinephrine, bdnf expression and creb activation in the dentate gyrus were increased, and the spatial learning and memory abilities were enhanced in crs rats. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
furthermore, in crs rats, propranolol significantly decreased the spatial learning and memory abilities, and attenuated the fepsp response during mwm test, and the bdnf expression and creb activation in the dentate gyrus. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
our results suggest that norepinephrine activation of β-adrenoceptors in the hippocampal dentate gyrus is involved in spatial learning and memory enhancement induced by crs in aged rats, in part via modulations of synaptic efficiency and creb-bdnf signaling pathway. |
2021-11-15 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
adult neurogenesis in the hippocampal dentate gyrus plays a critical role in learning and memory. |
2021-11-11 |
2023-08-13 |
rat |
| Daymara Mercerón-Martínez, William Almaguer-Melian, Jorge A Bergad. Basolateral amygdala stimulation plus water maze training restore dentate gyrus LTP and improve spatial learning and memory. Behavioural brain research. vol 417. 2021-11-08. PMID:34547342. |
basolateral amygdala stimulation plus water maze training restore dentate gyrus ltp and improve spatial learning and memory. |
2021-11-08 |
2023-08-13 |
rat |
| Ning-Xi Zeng, Hui-Zhen Li, Han-Zhang Wang, Kai-Ge Liu, Xia-Yu Gong, Wu-Long Luo, Can Yan, Li-Li W. Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression. Neural regeneration research. vol 17. issue 3. 2021-11-02. PMID:34380904. |
the results showed that ica alleviated depressive symptoms, learning and memory dysfunction, dysfunctional neurogenesis, and neuronal loss in the dentate gyrus of rats with depression. |
2021-11-02 |
2023-08-13 |
rat |
| Daniel Bormann, Tamara Stojanovic, Ana Cicvaric, Gabor J Schuld, Maureen Cabatic, Hendrik Jan Ankersmit, Francisco J Monj. miRNA-132/212 Gene-Deletion Aggravates the Effect of Oxygen-Glucose Deprivation on Synaptic Functions in the Female Mouse Hippocampus. Cells. vol 10. issue 7. 2021-10-28. PMID:34359879. |
using hippocampal slices from female mirna-132/212 double-knockout mice in an established electrophysiological model of ischemia, we here describe that mirna-132/212 gene-deletion aggravated the deleterious effect of repeated oxygen-glucose deprivation insults on synaptic transmission in the dentate gyrus, a brain region crucial for learning and memory functions. |
2021-10-28 |
2023-08-13 |
mouse |
| Yang Hee Kim, Joon Ha Par. Vanillin and 4-hydroxybenzyl alcohol attenuate cognitive impairment and the reduction of cell proliferation and neuroblast differentiation in the dentate gyrus in a mouse model of scopolamine-induced amnesia. Anatomy & cell biology. vol 50. issue 2. 2021-10-25. PMID:28713618. |
in this study, we examined effects of vanillin and 4-hba on learning and memory function, cell proliferation, and neuroblast differentiation in the hippocampal dentate gyrus in a mouse model of scopolamine-induced amnesia. |
2021-10-25 |
2023-08-13 |
mouse |
| Yang Hee Kim, Joon Ha Par. Vanillin and 4-hydroxybenzyl alcohol attenuate cognitive impairment and the reduction of cell proliferation and neuroblast differentiation in the dentate gyrus in a mouse model of scopolamine-induced amnesia. Anatomy & cell biology. vol 50. issue 2. 2021-10-25. PMID:28713618. |
treatment with scopolamine alone impaired learning and memory function in the morris water maze and passive avoidance tests, in addition, the treatment significantly reduced cell proliferation and neuroblast differentiation in the dentate gyrus, which were examined by immunohistochemistry for ki-67 (a classic marker for cell proliferation) and doublecortin (a marker for neuroblasts). |
2021-10-25 |
2023-08-13 |
mouse |
| Yang Hee Kim, Joon Ha Par. Vanillin and 4-hydroxybenzyl alcohol attenuate cognitive impairment and the reduction of cell proliferation and neuroblast differentiation in the dentate gyrus in a mouse model of scopolamine-induced amnesia. Anatomy & cell biology. vol 50. issue 2. 2021-10-25. PMID:28713618. |
however, treatment with vanillin or 4-hba significantly attenuated sco-induced learning and memory impairment as well as the reduction of cell proliferation and neuroblast differentiation in the dentate gyrus. |
2021-10-25 |
2023-08-13 |
mouse |
| Nathan A DeCarolis, Phillip D Rivera, Francisca Ahn, Wellington Z Amaral, Junie A LeBlanc, Shveta Malhotra, Hung-Ying Shih, David Petrik, Neal Melvin, Benjamin P C Chen, Amelia J Eisc. Life sciences in space research. vol 2. 2021-10-21. PMID:25170435. |
given that neurogenesis in the hippocampus has been linked to learning and memory, we investigated the response and recovery of neurogenesis and neural stem cells in the adult mouse hippocampal dentate gyrus after hze particle exposure using two nestin transgenic reporter mouse lines to label and track radial glia stem cells (nestin-gfp and nestin-creer |
2021-10-21 |
2023-08-13 |
mouse |