| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| An Schreurs, Victor Sabanov, Detlef Balschu. Distinct Properties of Long-Term Potentiation in the Dentate Gyrus along the Dorsoventral Axis: Influence of Age and Inhibition. Scientific reports. vol 7. issue 1. 2019-01-16. PMID:28698637. |
long-term potentiation (ltp), the best-investigated cellular correlate of learning and memory, has distinct properties along this axis in the ca1 region, but so far, little is known about longitudinal differences in dentate gyrus (dg). |
2019-01-16 |
2023-08-13 |
mouse |
| Ting Sun, Yu-Jiao Li, Qin-Qin Tian, Qi Wu, Dan Feng, Zhe Xue, Yan-Yan Guo, Le Yang, Kun Zhang, Ming-Gao Zhao, Yu-Mei W. Activation of liver X receptor β-enhancing neurogenesis ameliorates cognitive impairment induced by chronic cerebral hypoperfusion. Experimental neurology. vol 304. 2019-01-07. PMID:29447944. |
gw3965, a synthetic dual agonist for both lxrα and lxrβ, ameliorated impairment of learning and memory in cch mice by promoting neuronal survival and neural stem cells (nscs) proliferation in dentate gyrus (dg) of cch mice. |
2019-01-07 |
2023-08-13 |
mouse |
| Gerardo Bernabé Ramírez-Rodríguez, María Del Ángel Ocaña-Fernández, Leonardo Ortiz-Lópe. Newly Generated Cells in the Dentate Gyrus Differentially Respond to Brief Spatial Exploration and Forced Swim in Adult Female Balb/C Mice. Neural plasticity. vol 2018. 2018-11-27. PMID:29951090. |
in addition to their involvement in learning and memory processes, newborn neurons of the dentate gyrus (dg) buffer against the effects of stress. |
2018-11-27 |
2023-08-13 |
mouse |
| Tae-Woon Kim, Hye-Sang Par. Physical exercise improves cognitive function by enhancing hippocampal neurogenesis and inhibiting apoptosis in male offspring born to obese mother. Behavioural brain research. vol 347. 2018-11-13. PMID:29551732. |
the result showed that deficits in spatial learning and memory, and short-term memory in male offspring born to obese mothers was associated with decreases in brain-derived neurotrophic factor (bdnf) levels and neurogenesis, and an increase in apoptosis in the hippocampal dentate gyrus. |
2018-11-13 |
2023-08-13 |
rat |
| Tae-Woon Kim, Hye-Sang Par. Physical exercise improves cognitive function by enhancing hippocampal neurogenesis and inhibiting apoptosis in male offspring born to obese mother. Behavioural brain research. vol 347. 2018-11-13. PMID:29551732. |
physical exercise improved spatial learning and memory, and short-term memory by enhancing bdnf levels and neurogenesis, and by inhibiting apoptosis in the hippocampal dentate gyrus of male offspring born to obese mothers. |
2018-11-13 |
2023-08-13 |
rat |
| Meng Zhang, Dong Chen, Jing Xia, Wenqi Han, Xiekui Cui, Nils Neuenkirchen, Gretchen Hermes, Nenad Sestan, Haifan Li. Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes & development. vol 31. issue 13. 2018-08-21. PMID:28794184. |
here we report that neural-specific inactivation of two murine post-transcriptional regulators, pumilio 1 (pum1) and pum2, severely reduced the number of neural stem cells (nscs) in the postnatal dentate gyrus (dg), drastically increased perinatal apoptosis, altered dg cell composition, and impaired learning and memory. |
2018-08-21 |
2023-08-13 |
mouse |
| Chu-Wei Huang, Yi-Wen Chen, Yi-Rou Lin, Po-Han Chen, Meng-Hsuan Chou, Li-Jen Lee, Pei-Yu Wang, June-Tai Wu, Yeou-Ping Tsao, Show-Li Che. Conditional Knockout of Breast Carcinoma Amplified Sequence 2 (BCAS2) in Mouse Forebrain Causes Dendritic Malformation via β-catenin. Scientific reports. vol 6. 2018-06-25. PMID:27713508. |
bcas2 cko mice showed a microcephaly-like phenotype with a reduced volume in the dentate gyrus (dg) and low levels of learning and memory, as evaluated using morris water maze analysis and passive avoidance, respectively. |
2018-06-25 |
2023-08-13 |
mouse |
| Carolyn Hollands, Matthew Kyle Tobin, Michael Hsu, Kianna Musaraca, Tzong-Shiue Yu, Rachana Mishra, Steven G Kernie, Orly Lazaro. Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition. Molecular neurodegeneration. vol 12. issue 1. 2018-06-08. PMID:28886753. |
neurogenesis in the adult hippocampus is a dynamic process that continuously changes the dentate gyrus and is important for hippocampal plasticity, learning and memory. |
2018-06-08 |
2023-08-13 |
mouse |
| Jing Lv, Hao Feng, Ling Chen, Wei-Yao Wang, Xue-Ling Yue, Qing-Hua Ji. Activation of β-adrenoceptor facilitates active avoidance learning through enhancement of glutamate levels in the hippocampal dentate gyrus. Neuroreport. vol 28. issue 15. 2018-05-23. PMID:28877104. |
despite a number of studies indicating that β-adrenoceptors in the hippocampal dentate gyrus (dg) is involved in the modulation of learning and memory as well as ltp, few studies have used glutamate release as a visual indicator in awake animals to explore the role of β-adrenoceptors in learning-dependent ltp. |
2018-05-23 |
2023-08-13 |
rat |
| Junli Zhen, Yanjing Qian, Jian Fu, Ruijun Su, Haiting An, Wei Wang, Yan Zheng, Xiaomin Wan. Deep Brain Magnetic Stimulation Promotes Neurogenesis and Restores Cholinergic Activity in a Transgenic Mouse Model of Alzheimer's Disease. Frontiers in neural circuits. vol 11. 2018-05-02. PMID:28713248. |
in this study, we investigated the effect of dms on spatial learning and memory functions, neurogenesis in the dentate gyrus (dg), as well as expression and activity of the cholinergic system in a transgenic mouse model of ad (5xfad). |
2018-05-02 |
2023-08-13 |
mouse |
| Hidenori Ito, Rika Morishita, Koh-Ichi Nagat. Autism spectrum disorder-associated genes and the development of dentate granule cells. Medical molecular morphology. vol 50. issue 3. 2018-04-23. PMID:28534217. |
neuroanatomical observations have been made of developmental abnormalities in different brain regions, including dentate gyrus of hippocampus, which is widely accepted as the center for learning and memory. |
2018-04-23 |
2023-08-13 |
Not clear |
| Sabrina Oishi, Susitha Premarathne, Tracey J Harvey, Swati Iyer, Chantelle Dixon, Suzanne Alexander, Thomas H J Burne, Stephen A Wood, Michael Pipe. Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus. Scientific reports. vol 6. 2018-03-26. PMID:27181636. |
neurogenesis within the adult dentate gyrus contributes to learning and memory, and deficiencies in neurogenesis have been linked to cognitive decline. |
2018-03-26 |
2023-08-13 |
mouse |
| Rachel H Kennedy, Amen Wiqas, James P Curle. Evidence for mast cell-mediated zinc homeostasis: Increased labile zinc in the hippocampus of mast-cell deficient mice. Neuroscience letters. vol 650. 2018-03-19. PMID:28445769. |
the dentate gyrus of the hippocampus is a site of adult neurogenesis, and is also known to contain one of the highest concentrations of labile brain zinc (zn), thought to aid in learning and memory by supporting neurogenesis. |
2018-03-19 |
2023-08-13 |
mouse |
| Louise Ørum Olesen, Mithula Sivasaravanaparan, Maurizio Severino, Alicia A Babcock, Elena V Bouzinova, Mark J West, Ove Wiborg, Bente Finse. Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APP Neurobiology of disease. vol 104. 2018-03-19. PMID:28461249. |
neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged app altered neurogenesis may influence hippocampal functions such as learning and memory in alzheimer's disease. |
2018-03-19 |
2023-08-13 |
mouse |
| Petnoi Petsophonsakul, Kevin Richetin, Trinovita Andraini, Laurent Roybon, Claire Rampo. Memory formation orchestrates the wiring of adult-born hippocampal neurons into brain circuits. Brain structure & function. vol 222. issue 6. 2018-01-30. PMID:28062924. |
new neurons generated throughout the adult life in the dentate gyrus of the hippocampus contribute to learning and memory. |
2018-01-30 |
2023-08-13 |
Not clear |
| Kevin N Hascup, Erin R Hascu. Soluble Amyloid-β42 Stimulates Glutamate Release through Activation of the α7 Nicotinic Acetylcholine Receptor. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-29. PMID:27163813. |
because aβ42 binds the α7 nicotinic acetylcholine receptors (α7nachrs) located presynaptically on glutamatergic terminals, involved with hippocampal dependent learning and memory, we examined the effects of the human, monomeric isoform of aβ42 on glutamate release in the dentate gyrus (dg), ca3, and ca1, of isoflurane anesthetized, 6-9 month old male c57bl/6j mice. |
2018-01-29 |
2023-08-13 |
mouse |
| Muneaki Miyata, Tomohiko Maruo, Aika Kaito, Shujie Wang, Hideaki Yamamoto, Takeshi Fujiwara, Akira Mizoguchi, Kenji Mandai, Yoshimi Taka. Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus. Molecular and cellular neurosciences. vol 79. 2018-01-12. PMID:28041940. |
the hippocampal formation with tightly packed neurons, mainly at the dentate gyrus, ca3, ca2, and ca1 regions, constitutes a one-way neural circuit, which is associated with learning and memory. |
2018-01-12 |
2023-08-13 |
mouse |
| Carmen Vivar, Benjamin D Peterson, Henriette van Praa. Running rewires the neuronal network of adult-born dentate granule cells. NeuroImage. vol 131. 2018-01-08. PMID:26589333. |
running increases neurogenesis in the dentate gyrus of the hippocampus, a brain area important for learning and memory. |
2018-01-08 |
2023-08-13 |
mouse |
| Vallent Lee, Georgina MacKenzie, Andrew Hooper, Jamie Maguir. Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory. Hippocampus. vol 26. issue 10. 2018-01-08. PMID:27163381. |
reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory. |
2018-01-08 |
2023-08-13 |
mouse |
| Greg Stratmann, Jeffrey W Sall, Laura D V May, Andreas W Loepke, Michael T Le. Beyond anesthetic properties: the effects of isoflurane on brain cell death, neurogenesis, and long-term neurocognitive function. Anesthesia and analgesia. vol 110. issue 2. 2017-12-20. PMID:25508825. |
neurogenesis both in the developing and adult dentate gyrus is important for hippocampal function, specifically learning and memory. |
2017-12-20 |
2023-08-13 |
human |