| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachen Singhakumar, Parichart Boontem, Kasima Ekthuwapranee, Areechun Sotthibundhu, Sujira Mukda, Banthit Chetsawang, Piyarat Govitrapon. Melatonin attenuates methamphetamine-induced inhibition of neurogenesis in the adult mouse hippocampus: An in vivo study. Neuroscience letters. vol 606. 2016-03-03. PMID:26366944. |
newly born neurons in the dentate gyrus of the hippocampus play an important role in spatial learning and memory. |
2016-03-03 |
2023-08-13 |
mouse |
| Lindsay S Cahill, Patrick E Steadman, Carly E Jones, Christine L Laliberté, Jun Dazai, Jason P Lerch, Bojana Stefanovic, John G Sle. MRI-detectable changes in mouse brain structure induced by voluntary exercise. NeuroImage. vol 113. 2016-02-08. PMID:25800209. |
we found that exercise induced changes in multiple brain structures that are involved in motor function and learning and memory including the hippocampus, dentate gyrus, stratum granulosum of the dentate gyrus, cingulate cortex, olivary complex, inferior cerebellar peduncle and regions of the cerebellum. |
2016-02-08 |
2023-08-13 |
mouse |
| Hirofumi Noguchi, Ayaka Kimura, Naoya Murao, Taito Matsuda, Masakazu Namihira, Kinichi Nakashim. Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus. Neuroscience research. vol 95. 2016-01-19. PMID:25659757. |
adult neurogenesis persists throughout life in the dentate gyrus (dg) of the hippocampus, and its importance has been highlighted in hippocampus-dependent learning and memory. |
2016-01-19 |
2023-08-13 |
Not clear |
| Tushar K Bhattacharya, Brandt D Pence, Jessica M Ossyra, Trisha E Gibbons, Samuel Perez, Robert H McCusker, Keith W Kelley, Rodney W Johnson, Jeffrey A Woods, Justin S Rhode. Exercise but not (-)-epigallocatechin-3-gallate or β-alanine enhances physical fitness, brain plasticity, and behavioral performance in mice. Physiology & behavior. vol 145. 2016-01-04. PMID:25797079. |
the objective of this study was to determine the effects of egcg (~250mg/kg/day), b-ala (~550mg/kg/day), and their combination with voluntary wheel running exercise on the following outcome measures: body composition, time to fatigue, production of new cells in the granule layer of the dentate gyrus of the hippocampus as a marker for neuronal plasticity, and behavioral performance on the contextual and cued fear conditioning tasks, as measures of associative learning and memory. |
2016-01-04 |
2023-08-13 |
mouse |
| Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steine. Human adipose-derived mesenchymal stem cells improve motor functions and are neuroprotective in the 6-hydroxydopamine-rat model for Parkinson's disease when cultured in monolayer cultures but suppress hippocampal neurogenesis and hippocampal memory function when cultured in spheroids. Stem cell reviews and reports. vol 11. issue 1. 2015-12-04. PMID:25120226. |
in contrast, smsc grafting induced an increased local microgliosis, decreased th levels in the sn and reduced numbers of newly generated cells in the dentate gyrus (dg) without yet affecting hippocampal learning and memory function. |
2015-12-04 |
2023-08-13 |
human |
| Sophie Tronel, Valérie Lemaire, Vanessa Charrier, Marie-Françoise Montaron, Djoher Nora Abrou. Influence of ontogenetic age on the role of dentate granule neurons. Brain structure & function. vol 220. issue 2. 2015-11-16. PMID:24510284. |
new neurons are continuously produced in the adult dentate gyrus of the hippocampus, a key structure in learning and memory. |
2015-11-16 |
2023-08-12 |
rat |
| Rory Finnegan, Suzanna Becke. Neurogenesis paradoxically decreases both pattern separation and memory interference. Frontiers in systems neuroscience. vol 9. 2015-10-27. PMID:26500511. |
since the discovery of adult hippocampal neurogenesis in the dentate gyrus by altman and das in the 1960's, many theories and models have been put forward to explain the functional role it plays in learning and memory. |
2015-10-27 |
2023-08-13 |
Not clear |
| Rory Finnegan, Suzanna Becke. Neurogenesis paradoxically decreases both pattern separation and memory interference. Frontiers in systems neuroscience. vol 9. 2015-10-27. PMID:26500511. |
these models postulate different ways in which new neurons are introduced into the dentate gyrus and their functional importance for learning and memory. |
2015-10-27 |
2023-08-13 |
Not clear |
| M D Brandt, E Ellwardt, A Storc. Short- and long-term treatment with modafinil differentially affects adult hippocampal neurogenesis. Neuroscience. vol 278. 2015-10-20. PMID:25158676. |
the generation of new neurons in the dentate gyrus of the adult brain has been demonstrated in many species including humans and is suggested to have functional relevance for learning and memory. |
2015-10-20 |
2023-08-13 |
mouse |
| Anka D Mueller, Peter Meerlo, Dennis McGinty, Ralph E Mistlberge. Sleep and adult neurogenesis: implications for cognition and mood. Current topics in behavioral neurosciences. vol 25. 2015-10-09. PMID:24218292. |
the hippocampal dentate gyrus plays a critical role in learning and memory throughout life, in part by the integration of adult-born neurons into existing circuits. |
2015-10-09 |
2023-08-12 |
Not clear |
| Carlos Santos-Filho, Camila M de Lima, César A R Fôro, Marcus A de Oliveira, Nara G M Magalhães, Cristovam Guerreiro-Diniz, Daniel G Diniz, Pedro F da C Vasconcelos, Cristovam W P Dini. Visuospatial learning and memory in the Cebus apella and microglial morphology in the molecular layer of the dentate gyrus and CA1 lacunosum molecular layer. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25462387. |
visuospatial learning and memory in the cebus apella and microglial morphology in the molecular layer of the dentate gyrus and ca1 lacunosum molecular layer. |
2015-07-31 |
2023-08-13 |
monkey |
| Carlos Santos-Filho, Camila M de Lima, César A R Fôro, Marcus A de Oliveira, Nara G M Magalhães, Cristovam Guerreiro-Diniz, Daniel G Diniz, Pedro F da C Vasconcelos, Cristovam W P Dini. Visuospatial learning and memory in the Cebus apella and microglial morphology in the molecular layer of the dentate gyrus and CA1 lacunosum molecular layer. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25462387. |
we investigated whether the morphology of microglia in the molecular layer of the dentate gyrus (dg-mol) or in the lacunosum molecular layer of ca1 (ca1-lmol) was correlated with spatial learning and memory in the capuchin monkey (cebus apella). |
2015-07-31 |
2023-08-13 |
monkey |
| Benjamin Chew, Jae Ryun Ryu, Teclise Ng, Dongliang Ma, Ananya Dasgupta, Sin Hui Neo, Jing Zhao, Zhong Zhong, Zoë Bichler, Sreedharan Sajikumar, Eyleen L K Go. Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity. Frontiers in behavioral neuroscience. vol 9. 2015-07-09. PMID:26157370. |
our study aims to better understand the role of gsk3β in learning and memory through a more regionally, targeted approach, specifically performing lentiviral-mediated knockdown of gsk3β within the dentate gyrus (dg). |
2015-07-09 |
2023-08-13 |
mouse |
| Xuan Zhao, Rui xue Zhang, Shi Tang, Yan yan Ren, Wei xia Yang, Xiao min Liu, Ji you Tan. Orexin-A-induced ERK1/2 activation reverses impaired spatial learning and memory in pentylenetetrazol-kindled rats via OX1R-mediated hippocampal neurogenesis. Peptides. vol 54. 2015-05-13. PMID:24321199. |
thus, we used pentylenetetrazol (ptz)-kindled rats to investigate the effects of orexin-a on learning and memory and the involvement of neurogenesis in the dentate gyrus in ox1r-mediated erk1/2 activation. |
2015-05-13 |
2023-08-12 |
rat |
| Xuan Zhao, Rui xue Zhang, Shi Tang, Yan yan Ren, Wei xia Yang, Xiao min Liu, Ji you Tan. Orexin-A-induced ERK1/2 activation reverses impaired spatial learning and memory in pentylenetetrazol-kindled rats via OX1R-mediated hippocampal neurogenesis. Peptides. vol 54. 2015-05-13. PMID:24321199. |
taken together, these data suggest that orexin-a attenuated the impairment of spatial learning and memory in ptz-kindled rats and that this attenuation involved neurogenesis in the dentate gyrus via ox1r-mediated erk1/2 activation. |
2015-05-13 |
2023-08-12 |
rat |
| Claudia Fuchs, Stefania Trazzi, Roberta Torricella, Rocchina Viggiano, Marianna De Franceschi, Elena Amendola, Cornelius Gross, Laura Calzà, Renata Bartesaghi, Elisabetta Cian. Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. Neurobiology of disease. vol 70. 2015-04-21. PMID:24952363. |
we mainly focused on the hippocampal dentate gyrus, a region that largely develops postnatally and plays a key role in learning and memory. |
2015-04-21 |
2023-08-13 |
mouse |
| Yoori Choi, Kihwan Lee, Junghwa Ryu, Hyoun Geun Kim, A Young Jeong, Ran-Sook Woo, Jun-Ho Lee, Jin Won Hyun, Seokyung Hahn, Joung-Hun Kim, Hye-Sun Ki. Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease. PloS one. vol 9. issue 8. 2015-04-21. PMID:25101829. |
in this study, we found that the cortical and hippocampal expression of neuritin is reduced in the brains of alzheimer's disease (ad) patients and demonstrated that viral-mediated expression of neuritin in the dentate gyrus of 13-month-old tg2576 mice, an ad animal model, attenuated a deficit in learning and memory as assessed by a morris water maze test. |
2015-04-21 |
2023-08-13 |
mouse |
| Yilong Dong, Aimei Jiang, Hongju Yang, Huicheng Chen, Yanmei Wan. Phytoestrogen α-zearalanol improves memory impairment and hippocampal neurogenesis in ovariectomized mice. TheScientificWorldJournal. vol 2014. 2015-04-15. PMID:25143992. |
our findings demonstrated that ovx resulted in impaired spatial learning and memory and reduced numbers of newborn neurons in the dentate gyrus of the hippocampus, while 17β-e2 or α-zal treatment significantly improved memory performance and restored hippocampal neurogenesis. |
2015-04-15 |
2023-08-13 |
mouse |
| Christine Manrique, Martine Migliorati, Valérie Gilbert, Jean-Michel Brezun, Franck A Chaillan, Bruno Truchet, Michel Khrestchatisky, Gaëlle Guiraudie-Capraz, François S Roma. Dynamic expression of the polysialyltransferase in adult rat hippocampus performing an olfactory associative task. Hippocampus. vol 24. issue 8. 2015-03-30. PMID:24753009. |
then, ncam polysialylation and cell proliferation were quantified in the dentate gyrus of a "learning and memory" group using immunohistochemistry. |
2015-03-30 |
2023-08-13 |
rat |
| Robert Nunan, Harri Sivasathiaseelan, Damla Khan, Malik Zaben, William Gra. Microglial VPAC1R mediates a novel mechanism of neuroimmune-modulation of hippocampal precursor cells via IL-4 release. Glia. vol 62. issue 8. 2015-02-04. PMID:24801739. |
neurogenesis, the production of new neurons from neural stem/progenitor cells (nspcs), occurs throughout adulthood in the dentate gyrus of the hippocampus, where it supports learning and memory. |
2015-02-04 |
2023-08-13 |
Not clear |