| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guangxie Li, Jing Lv, Jun Wang, Peng Wan, Yingshun Li, Haiying Jiang, Qinghua Ji. GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia. Brain research bulletin. vol 124. 2017-10-26. PMID:27181927. |
gabab receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia. |
2017-10-26 |
2023-08-13 |
rat |
| Guangxie Li, Jing Lv, Jun Wang, Peng Wan, Yingshun Li, Haiying Jiang, Qinghua Ji. GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia. Brain research bulletin. vol 124. 2017-10-26. PMID:27181927. |
the roles of γ-aminobutyric acid (gaba) and gabab receptors of the hippocampal dentate gyrus (dg) in spatial learning and memory impairment were investigated in a rat model of vascular dementia (vad) established by permanent bilateral carotid occlusion. |
2017-10-26 |
2023-08-13 |
rat |
| Wei Lu, Shu Yang, Lei Zhang, Lin Chen, Feng-Lei Chao, Yan-Min Luo, Qian Xiao, Heng-Wei Gu, Rong Jiang, Yong Tan. Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer's Disease. Current Alzheimer research. vol 13. issue 9. 2017-10-16. PMID:26971933. |
our results showed that spatial learning and memory performance was significantly impaired in the tg2576 mice compared to the wild type (wt) controls and that the myelinated fiber length in the hippocampal dentate gyrus (dg) was markedly decreased from 0.33 ± 0.03 km in the wt controls to 0.17 ± 0.02 km in the tg2576 mice at 10 months of age. |
2017-10-16 |
2023-08-13 |
mouse |
| Jun Li, Zhou Han, Bo Cao, Cheng-Yun Cai, Yu-Hui Lin, Fei Li, Hai-Ying Wu, Lei Chang, Chun-Xia Luo, Dong-Ya Zh. Disrupting nNOS-PSD-95 coupling in the hippocampal dentate gyrus promotes extinction memory retrieval. Biochemical and biophysical research communications. vol 493. issue 1. 2017-10-16. PMID:28888982. |
granule cells in the dentate gyrus regenerate constantly in adult hippocampus and then integrate into neural circuits in the hippocampus thereby providing the neural basis for learning and memory. |
2017-10-16 |
2023-08-13 |
Not clear |
| Kevin N Hascup, Mary K Lynn, Patrick J Fitzgerald, Shari Randall, John J Kopchick, Heather A Boger, Andrzej Bartke, Erin R Hascu. Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 72. issue 3. 2017-08-10. PMID:27208894. |
spatial learning and memory were assessed using the morris water maze (mwm), whereas independent dentate gyrus (dg), ca3, and ca1 basal glutamate, release, and uptake measurements were conducted in isoflurane anesthetized mice utilizing an enzyme-based microelectrode array (mea) coupled with constant potential amperometry. |
2017-08-10 |
2023-08-13 |
mouse |
| Anna K Gillespie, Emily A Jones, Yuan-Hung Lin, Mattias P Karlsson, Kenneth Kay, Seo Yeon Yoon, Leslie M Tong, Philip Nova, Jessie S Carr, Loren M Frank, Yadong Huan. Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples. Neuron. vol 90. issue 4. 2017-08-03. PMID:27161522. |
in knockin (ki) mice, human apoe4 causes age-dependent learning and memory impairments and degeneration of gabaergic interneurons in the hippocampal dentate gyrus. |
2017-08-03 |
2023-08-13 |
mouse |
| Gregor-Alexander Pilz, Stefano Carta, Andreas Stäuble, Asll Ayaz, Sebastian Jessberger, Fritjof Helmche. Functional Imaging of Dentate Granule Cells in the Adult Mouse Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 28. 2017-07-18. PMID:27413151. |
the hippocampal dentate gyrus is critically involved in learning and memory. |
2017-07-18 |
2023-08-13 |
mouse |
| Qian-Qian Yang, Wei-Zhen Xue, Rong-Xin Zou, Yi Xu, Yang Du, Shuang Wang, Lai Xu, Yuan-Zhi Chen, Hui-Li Wang, Xiang-Tao Che. β-Asarone Rescues Pb-Induced Impairments of Spatial Memory and Synaptogenesis in Rats. PloS one. vol 11. issue 12. 2017-07-11. PMID:27936013. |
and β-asarone effectively attenuated pb-induced reduction of spine density in hippocampal ca1 and dentate gyrus areas in a dose-dependent manner both in developmental and adult rats, meanwhile the pb-induced impairments of learning and memory were partially rescued. |
2017-07-11 |
2023-08-13 |
rat |
| Jiook Cha, Johanna A Zea-Hernandez, Sanghun Sin, Katharina Graw-Panzer, Keivan Shifteh, Carmen R Isasi, Mark E Wagshul, Eileen E Moran, Jonathan Posner, Molly E Zimmerman, Raanan Aren. The Effects of Obstructive Sleep Apnea Syndrome on the Dentate Gyrus and Learning and Memory in Children. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 16. 2017-04-28. PMID:28320844. |
the effects of obstructive sleep apnea syndrome on the dentate gyrus and learning and memory in children. |
2017-04-28 |
2023-08-13 |
Not clear |
| Megumi Nakai, Michiro Iizuka, Nobuaki Matsui, Kazuko Hosogi, Akiko Imai, Noriaki Abe, Hisashi Shiraishi, Ayumu Hirata, Yusuke Yagi, Kohei Jobu, Junko Yokota, Eishin Kato, Shinya Hosoda, Saburo Yoshioka, Kenichi Harada, Miwa Kubo, Yoshiyasu Fukuyama, Mitsuhiko Miyamur. Bangle (Zingiber purpureum) Improves Spatial Learning, Reduces Deficits in Memory, and Promotes Neurogenesis in the Dentate Gyrus of Senescence-Accelerated Mouse P8. Journal of medicinal food. vol 19. issue 5. 2017-03-20. PMID:26829513. |
we found that the bangle-containing diet improved spatial learning and memory deficits in the morris water maze and significantly increased the numbers of ki67-positive cells in the dentate gyrus of the samp8 mice. |
2017-03-20 |
2023-08-13 |
mouse |
| Jianying Tian, Yougen Luo, Weiwei Chen, Shengsen Yang, Hao Wang, Jing Cui, Zhiyan Lu, Yuanye Lin, Yongyi B. MeHg Suppressed Neuronal Potency of Hippocampal NSCs Contributing to the Puberal Spatial Memory Deficits. Biological trace element research. vol 172. issue 2. 2017-02-03. PMID:26743863. |
mehg exposure induced defects in spatial learning and memory accompanied by a decrease in number of doublecortin (dcx)-positive cells in the dentate gyrus (dg). |
2017-02-03 |
2023-08-13 |
rat |
| Sui-Jun Guo, Yu Cui, Zhen-Zhen Huang, Huan Liu, Xue-Qin Zhang, Jin-Xiang Jiang, Wen-Jun Xi. Orexin A-mediated AKT signaling in the dentate gyrus contributes to the acquisition, expression and reinstatement of morphine-induced conditioned place preference. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25757577. |
accumulating evidence indicates that the hippocampal dentate gyrus (dg), a critical brain region contributing to learning and memory, is involved in the addiction and relapse to abused drugs. |
2017-01-10 |
2023-08-13 |
rat |
| Huijuan Jin, Lei Pei, Xiaogang Shu, Xin Yang, Tianhua Yan, Yan Wu, Na Wei, Honglin Yan, Shan Wang, Chengye Yao, Dan Liu, Qing Tian, Lin Wang, Youming L. Therapeutic Intervention of Learning and Memory Decays by Salidroside Stimulation of Neurogenesis in Aging. Molecular neurobiology. vol 53. issue 2. 2016-11-14. PMID:25520005. |
here, we show that treatment with a nature product from a traditional chinese medicine, namely salidroside restores the capacity of the dentate gyrus to generate new neurons and intercepts learning and memory decays in mice during aging. |
2016-11-14 |
2023-08-13 |
mouse |
| S Monteiro, F M Ferreira, V Pinto, S Roque, M Morais, D de Sá-Calçada, C Mota, M Correia-Neves, J J Cerqueir. Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance. Translational psychiatry. vol 6. 2016-10-17. PMID:26731444. |
in the dorsal hippocampus, the absence of this pro-inflammatory cytokine leads to an increase in the numbers of newly born neurons in the subgranular zone of the dentate gyrus (dg), an adult neurogenic niche known to support learning and memory, and to an enlargement of the dendritic arborization of dg granule and cornu ammonis (ca)1 pyramidal neurons. |
2016-10-17 |
2023-08-13 |
Not clear |
| Jia Chen, Cheng-Ren Li, Heng Yang, Juan Liu, Tao Zhang, Shu-Sheng Jiao, Yan-Jiang Wang, Zhi-Qiang X. proBDNF Attenuates Hippocampal Neurogenesis and Induces Learning and Memory Deficits in Aged Mice. Neurotoxicity research. vol 29. issue 1. 2016-10-05. PMID:26459304. |
in the present study, we investigated the role of probdnf in neurogenesis in the hippocampal dentate gyrus of aged mice and examined the changes in mice learning and memory functions. |
2016-10-05 |
2023-08-13 |
mouse |
| Sophie Tronel, Vanessa Charrier, Cyrille Sage, Marlene Maitre, Thierry Leste-Lasserre, Djoher N Abrou. Adult-born dentate neurons are recruited in both spatial memory encoding and retrieval. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25913775. |
adult neurogenesis occurs in the dentate gyrus (dg) of the hippocampus, which is a key structure in learning and memory. |
2016-08-29 |
2023-08-13 |
rat |
| Yaning Liu, Shangwu Wang, Shijian Luo, Zhendong Li, Fengyin Liang, Yanan Zhu, Zhong Pei, Ruxun Huan. Intravenous PEP-1-GDNF is protective after focal cerebral ischemia in rats. Neuroscience letters. vol 617. 2016-08-08. PMID:26876444. |
further, pep-1-gdnf promoted the cell proliferation and differentiation in the dentate gyrus of the hippocampus and attenuated ischemia-induced learning and memory damage. |
2016-08-08 |
2023-08-13 |
rat |
| Hong Liu, Xinhong Xue, Huijian Shi, Lifeng Qi, Dianrong Gon. Osthole Upregulates BDNF to Enhance Adult Hippocampal Neurogenesis in APP/PS1 Transgenic Mice. Biological & pharmaceutical bulletin. vol 38. issue 10. 2016-07-25. PMID:26424009. |
adult hippocampal neurogenesis occurs in the dentate gyrus (dg) of the mouse hippocampus, and plays roles in learning and memory progresses. |
2016-07-25 |
2023-08-13 |
mouse |
| Elsa Suberbielle, Biljana Djukic, Mark Evans, Daniel H Kim, Praveen Taneja, Xin Wang, Mariel Finucane, Joseph Knox, Kaitlyn Ho, Nino Devidze, Eliezer Masliah, Lennart Muck. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. Nature communications. vol 6. 2016-06-29. PMID:26615780. |
in wild-type mice, knocking down neuronal brca1 in the dentate gyrus caused increased dna double-strand breaks, neuronal shrinkage, synaptic plasticity impairments, and learning and memory deficits, but not apoptosis. |
2016-06-29 |
2023-08-13 |
mouse |
| Huan-rui Sun, Na Zhang, Xue-wei Chen, Gai-hong An, Chuan-xiang Xu, Qiang M. [Effect of nano-SiO2 exposure on spatial learning and memory and LTP of hippocampal dentate gyrus in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 1. 2016-06-10. PMID:27255049. |
[effect of nano-sio2 exposure on spatial learning and memory and ltp of hippocampal dentate gyrus in rats]. |
2016-06-10 |
2023-08-13 |
rat |