| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei An, Zhuo Yang, Tao Zhan. Melamine induced spatial cognitive deficits associated with impairments of hippocampal long-term depression and cholinergic system in Wistar rats. Neurobiology of learning and memory. vol 100. 2013-07-23. PMID:23231966. |
water maze behavior and long-term depression (ltd) in hippocampal ca3-ca1 pathway were measured, followed by enzyme linked immunosorbent assay (elisa), by which acetylcholine (ach) level and acetylcholinesterase (ache) activity were determined. |
2013-07-23 |
2023-08-12 |
rat |
| Jinzhong Jeremy Goh, Denise Manahan-Vaugha. Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5. Hippocampus. vol 23. issue 2. 2013-07-22. PMID:22996287. |
recently, it was reported that in the mouse hippocampus intrinsic long-term depression (ltd > 24 h) occurs when test-pulse afferent stimulation is coupled with a novel spatial learning. |
2013-07-22 |
2023-08-12 |
mouse |
| Marco Pignatelli, Barbara Vollmayr, Sophie Helene Richter, Silvia Middei, Francesco Matrisciano, Gemma Molinaro, Carla Nasca, Giuseppe Battaglia, Martine Ammassari-Teule, Marco Feligioni, Robert Nisticò, Ferdinando Nicoletti, Peter Gas. Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats. Neuropharmacology. vol 66. 2013-07-02. PMID:22709946. |
correspondingly, dhpg-induced long-term depression (ltd) at schaffer collateral/ca1 pyramidal cell synapses was amplified in hippocampal slices of clh rats, whereas ltd induced by low frequency stimulation of the schaffer collaterals did not change. |
2013-07-02 |
2023-08-12 |
rat |
| Arne Buschler, Jinzhong Jeremy Goh, Denise Manahan-Vaugha. Frequency dependency of NMDA receptor-dependent synaptic plasticity in the hippocampal CA1 region of freely behaving mice. Hippocampus. vol 22. issue 12. 2013-06-27. PMID:22707377. |
hippocampal synaptic plasticity in the form of long-term potentiation (ltp) and long-term depression (ltd) is likely to enable synaptic information storage in support of memory formation. |
2013-06-27 |
2023-08-12 |
mouse |
| Zhenzhong Cui, Ruiben Feng, Stephanie Jacobs, Yanhong Duan, Huimin Wang, Xiaohua Cao, Joe Z Tsie. Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory. Scientific reports. vol 3. 2013-06-25. PMID:23301157. |
surprisingly, increased nr2a expression did not affect 1-hz-induced long-term depression (ltd) or 100 hz-induced long-term potentiation (ltp) in the ca1 region of the hippocampus, but selectively abolished ltd responses in the 3-5 hz frequency range. |
2013-06-25 |
2023-08-12 |
mouse |
| Robert Nisticò, Dalila Mango, Georgia Mandolesi, Sonia Piccinin, Nicola Berretta, Marco Pignatelli, Marco Feligioni, Alessandra Musella, Antonietta Gentile, Francesco Mori, Giorgio Bernardi, Ferdinando Nicoletti, Nicola B Mercuri, Diego Centonz. Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis. PloS one. vol 8. issue 1. 2013-06-24. PMID:23355887. |
when compared to control mice, in fact, hippocampal long-term potentiation (ltp) induction was favored over long-term depression (ltd) in eae, as shown by a significant rightward shift in the frequency-synaptic response function. |
2013-06-24 |
2023-08-12 |
mouse |
| Wei Xu, Yiu Chung Tse, Frederick A Dobie, Michel Baudry, Ann Marie Craig, Tak Pan Wong, Yu Tian Wan. Simultaneous monitoring of presynaptic transmitter release and postsynaptic receptor trafficking reveals an enhancement of presynaptic activity in metabotropic glutamate receptor-mediated long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 13. 2013-05-23. PMID:23536098. |
using this method to investigate presynaptic changes during the expression of group i metabotropic glutamate receptor (mglur1/5)-mediated long-term depression (ltd) in cultured rat hippocampal neurons, we discovered that this form of ltd was associated with increased presynaptic release of glutamate, despite reduced miniature epscs measured with whole-cell recording. |
2013-05-23 |
2023-08-12 |
rat |
| Francisco J Rubio, Estíbaliz Ampuero, Rodrigo Sandoval, Jorge Toledo, Floria Pancetti, Ursula Wyneke. Long-term fluoxetine treatment induces input-specific LTP and LTD impairment and structural plasticity in the CA1 hippocampal subfield. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675317. |
we evaluated the effect of four weeks of 0.7 mg/kg fluoxetine on long-term potentiation (ltp) and long-term depression (ltd) in the ca1 hippocampal subfield. |
2013-05-16 |
2023-08-12 |
rat |
| M J Noetzel, K J Gregory, P N Vinson, J T Manka, S R Stauffer, C W Lindsley, C M Niswender, Z Xiang, P J Con. A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling. Molecular pharmacology. vol 83. issue 4. 2013-05-14. PMID:23348500. |
furthermore, mglu5 has been shown to play an important role in hippocampal synaptic plasticity, specifically in long-term depression (ltd) and long-term potentiation (ltp), which is thought to be involved in cognition. |
2013-05-14 |
2023-08-12 |
Not clear |
| S Sasaki-Hamada, H Sacai, J-I Ok. Diabetes onset influences hippocampal synaptic plasticity in streptozotocin-treated rats. Neuroscience. vol 227. 2013-05-09. PMID:23069762. |
here we showed that synaptic plasticity including long-term potentiation (ltp) or long-term depression (ltd), and excitatory synaptic transmission at schaffer collateral-ca1 (sc-ca1) synapses in hippocampal slices were affected by age of onset in rats with streptozotocin-induced diabetes (stz-rats), compared with age-matched control rats. |
2013-05-09 |
2023-08-12 |
rat |
| Zhongfei Yang, Wencai Zhang, Ming Wang, Diyun Ruan, Jutao Che. Effects of daytime, night and sleep pressure on long-term depression in the hippocampus in vivo. Neuroscience letters. vol 511. issue 2. 2013-05-07. PMID:22322074. |
effects of daytime, night and sleep pressure on long-term depression in the hippocampus in vivo. |
2013-05-07 |
2023-08-12 |
rat |
| Jinsoo Seo, Jinpyo Hong, Sung Joong Lee, Se-Young Cho. c-Jun N-terminal phosphorylation is essential for hippocampal synaptic plasticity. Neuroscience letters. vol 531. issue 1. 2013-04-30. PMID:23041047. |
notably, however, the induction of long-term potentiation (ltp) at hippocampal ca3-ca1 synapses in c-junaa mice was impaired, whereas induction of long-term depression (ltd) was normal. |
2013-04-30 |
2023-08-12 |
mouse |
| Lara Costa, Michela Spatuzza, Simona D'Antoni, Carmela M Bonaccorso, Chiara Trovato, Sebastiano A Musumeci, Marcello Leopoldo, Enza Lacivita, Maria V Catania, Lucia Cirann. Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome. Biological psychiatry. vol 72. issue 11. 2013-04-23. PMID:22817866. |
fmr1 knockout (fmr1 ko) mice, an animal model of fxs, exhibit spatial memory impairment and synapse malfunctioning in the hippocampus, with abnormal enhancement of long-term depression mediated by metabotropic glutamate receptors (mglur-ltd). |
2013-04-23 |
2023-08-12 |
mouse |
| Mario Carta, Patrizio Opazo, Julien Veran, Axel Athané, Daniel Choquet, Françoise Coussen, Christophe Mull. CaMKII-dependent phosphorylation of GluK5 mediates plasticity of kainate receptors. The EMBO journal. vol 32. issue 4. 2013-04-19. PMID:23288040. |
we show that repeated pairing of pre- and postsynaptic stimulation at hippocampal mossy fibre synapses induces long-term depression of kainate receptor (kar)-mediated responses, which depends on ca(2+) influx, activation of camkii, and on the gluk5 subunit of kars. |
2013-04-19 |
2023-08-12 |
Not clear |
| Hiroki Fujiwara, Kotaro Ikarashi, Yoshihiko Yamazaki, Jun-Ichi Goto, Kenya Kaneko, Makoto Sugita, Hiroshi Kato, Hiroshi Sasaki, Jin-Ichi Inokuchi, Koichi Furukawa, Satoshi Fuji. Impairment of hippocampal long-term potentiation and failure of learning in mice treated with d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol. Biomedical research (Tokyo, Japan). vol 33. issue 5. 2013-03-25. PMID:23124246. |
in the present study, long-term potentiation (ltp) and long-term depression (ltd) in ca1 hippocampal neurons and learning behavior were examined in mice treated with (d)-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ((d)-pdmp), an inhibitor of ganglioside biosynthesis. |
2013-03-25 |
2023-08-12 |
mouse |
| Hardy Hagena, Denise Manahan-Vaugha. Differentiation in the protein synthesis-dependency of persistent synaptic plasticity in mossy fiber and associational/commissural CA3 synapses in vivo. Frontiers in integrative neuroscience. vol 7. 2013-03-06. PMID:23459947. |
long-term potentiation (ltp) and long-term depression (ltd) are two mechanisms involved in the long-term storage of information in hippocampal synapses. |
2013-03-06 |
2023-08-12 |
rat |
| Zhifang Dong, Yanrui Bai, Xiaoyan Wu, Hongjie Li, Bo Gong, John G Howland, Yan Huang, Wenting He, Tingyu Li, Yu Tian Wan. Hippocampal long-term depression mediates spatial reversal learning in the Morris water maze. Neuropharmacology. vol 64. 2013-02-11. PMID:22732443. |
hippocampal long-term depression mediates spatial reversal learning in the morris water maze. |
2013-02-11 |
2023-08-12 |
Not clear |
| Kwang-Mook Jung, Marja Sepers, Christopher M Henstridge, Olivier Lassalle, Daniela Neuhofer, Henry Martin, Melanie Ginger, Andreas Frick, Nicholas V DiPatrizio, Ken Mackie, Istvan Katona, Daniele Piomelli, Olivier J Manzon. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature communications. vol 3. 2013-02-01. PMID:23011134. |
fragile x mental retardation protein deletion in mice enhances metabotropic glutamate receptor-5-dependent long-term depression in the hippocampus and cerebellum. |
2013-02-01 |
2023-08-12 |
mouse |
| Claire Piochon, Peter Kruskal, Jason Maclean, Christian Hanse. Non-Hebbian spike-timing-dependent plasticity in cerebellar circuits. Frontiers in neural circuits. vol 6. 2013-01-22. PMID:23335888. |
at glutamatergic synapses onto hippocampal and neocortical pyramidal cells, synaptic activation followed by spike firing in the target cell causes long-term potentiation (ltp)-as predicted by hebb-whereas excitatory postsynaptic potentials (epsps) evoked after a spike elicit long-term depression (ltd)-a phenomenon that was not specifically addressed by hebb. |
2013-01-22 |
2023-08-12 |
Not clear |
| Tao Ma, Xueliang Du, Joseph E Pick, Guangzhi Sui, Michael Brownlee, Eric Klan. Glucagon-like peptide-1 cleavage product GLP-1(9-36) amide rescues synaptic plasticity and memory deficits in Alzheimer's disease model mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 40. 2013-01-17. PMID:23035082. |
here we report that pretreatment of hippocampal slices with glp-1(9-36)(amide) prevented impaired long-term potentiation (ltp) and enhanced long-term depression induced by exogenous amyloid β peptide aβ((1-42)). |
2013-01-17 |
2023-08-12 |
mouse |