| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuansheng Tan, Nobuaki Hori, David O Carpente. The mechanism of presynaptic long-term depression mediated by group I metabotropic glutamate receptors. Cellular and molecular neurobiology. vol 23. issue 2. 2003-12-04. PMID:12735631. |
in a study of rat hippocampal brain slices, we find that a brief perfusion of a group i mglur agonist, (s)-3,5-dihydroxyphenylglycine (dhpg), induced a robust long-term depression (dhpg-ltd) in area ca1. |
2003-12-04 |
2023-08-12 |
rat |
| Min-Min Zhang, Cheng Xiao, Kuai Yu, Di-Yun Rua. Effects of sodium valproate on synaptic plasticity in the CA1 region of rat hippocampus. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 41. issue 11. 2003-11-21. PMID:12963015. |
in the present study, we used two forms of synaptic plasticity, ltp and long-term depression (ltd) of field excitatory postsynaptic potential (fepsp) to investigate the effects of vpa on synaptic plasticity in rat hippocampal slices. |
2003-11-21 |
2023-08-12 |
rat |
| Saobo Lei, Kenneth A Pelkey, Lisa Topolnik, Patrice Congar, Jean-Claude Lacaille, Chris J McBai. Depolarization-induced long-term depression at hippocampal mossy fiber-CA3 pyramidal neuron synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 30. 2003-11-20. PMID:14586006. |
depolarization-induced long-term depression at hippocampal mossy fiber-ca3 pyramidal neuron synapses. |
2003-11-20 |
2023-08-12 |
Not clear |
| Thomas C Foster, Keith M Sharrow, Ashok Kumar, James Mass. Interaction of age and chronic estradiol replacement on memory and markers of brain aging. Neurobiology of aging. vol 24. issue 6. 2003-10-29. PMID:12927766. |
eb treatment reversed several hippocampal markers of age-related memory impairment, blocking induction of long-term depression and decreasing cytosolic calcineurin activity. |
2003-10-29 |
2023-08-12 |
rat |
| Anne Jouvenceau, Jean-Marie Billard, Ursula Haditsch, Isabelle M Mansuy, Patrick Duta. Different phosphatase-dependent mechanisms mediate long-term depression and depotentiation of long-term potentiation in mouse hippocampal CA1 area. The European journal of neuroscience. vol 18. issue 5. 2003-10-23. PMID:12956726. |
two types of synaptic depression have been described in the hippocampus, long-term depression and depotentiation of long-term potentiation known to recruit the serine/threonine protein phosphatases pp1, pp2a and pp2b (calcineurin). |
2003-10-23 |
2023-08-12 |
mouse |
| Anne Jouvenceau, Jean-Marie Billard, Ursula Haditsch, Isabelle M Mansuy, Patrick Duta. Different phosphatase-dependent mechanisms mediate long-term depression and depotentiation of long-term potentiation in mouse hippocampal CA1 area. The European journal of neuroscience. vol 18. issue 5. 2003-10-23. PMID:12956726. |
to examine the role of the ca2+/calmodulin-dependent protein phosphatase calcineurin in long-term depression and depotentiation, we analysed the effect of genetically inhibiting calcineurin reversibly in the hippocampus, using the doxycycline-dependent rtta system in transgenic mice. |
2003-10-23 |
2023-08-12 |
mouse |
| Nathalie Rouach, Roger A Nicol. Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus. The European journal of neuroscience. vol 18. issue 4. 2003-10-14. PMID:12925027. |
activation of postsynaptic group 1 metabotropic glutamate receptors (mglurs) by the agonist dhpg causes a long-term depression (dhpg-ltd) of excitatory transmission in the ca1 region of the hippocampus, as well as causing the release of endocannabinoids from pyramidal cells. |
2003-10-14 |
2023-08-12 |
mouse |
| S Aou, X-L Li, A-J Li, Y Oomura, T Shiraishi, K Sasaki, T Imamura, M J Wayne. Orexin-A (hypocretin-1) impairs Morris water maze performance and CA1-Schaffer collateral long-term potentiation in rats. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831875. |
the purpose of the present study was to assess the effects of orexin-a on the performance of wistar rats during the morris water maze test and then to determine the effects of orexin-a on both the long-term potentiation and long-term depression in schaffer collateral/commissural-ca1 synapses in hippocampal slices. |
2003-09-05 |
2023-08-12 |
rat |
| Valentin Stein, David R C House, David S Bredt, Roger A Nicol. Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 13. 2003-08-14. PMID:12843250. |
postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. |
2003-08-14 |
2023-08-12 |
Not clear |
| Valentin Stein, David R C House, David S Bredt, Roger A Nicol. Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 13. 2003-08-14. PMID:12843250. |
to determine whether this effect is related to synaptic plasticity at these synapses, we examined whether psd-95 expression mimics long-term potentiation (ltp), and also whether it influences ltp and long-term depression (ltd) in hippocampal slice cultures. |
2003-08-14 |
2023-08-12 |
Not clear |
| Detlef Balschun, David P Wolfer, Peter Gass, Theo Mantamadiotis, Hans Welzl, Günther Schütz, Julietta U Frey, Hans-Peter Lip. Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 15. 2003-08-13. PMID:12867515. |
in these strains, no deficits could be detected in lasting forms of hippocampal long-term potentiation (ltp) and long-term depression (ltd). |
2003-08-13 |
2023-08-12 |
mouse |
| Yanghong Meng, Yu Zhang, Zhengping Ji. Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3. Neuron. vol 39. issue 1. 2003-08-05. PMID:12848940. |
the ampa glutamate receptor (ampar) subunits glur2 and glur3 are thought to be important for synaptic targeting/stabilization of ampars and the expression of hippocampal long-term depression (ltd). |
2003-08-05 |
2023-08-12 |
mouse |
| J S Thinschmidt, D W Walker, M A Kin. Chronic ethanol treatment reduces the magnitude of hippocampal LTD in the adult rat. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687638. |
in the present report we examined the effects of cet on hippocampal long-term depression (ltd). |
2003-07-25 |
2023-08-12 |
human |
| Brendan P Curran, John J O'Conno. The inhibition of long-term potentiation in the rat dentate gyrus by pro-inflammatory cytokines is attenuated in the presence of nicotine. Neuroscience letters. vol 344. issue 2. 2003-07-14. PMID:12782338. |
nicotine has previously been shown to affect both long-term potentiation (ltp) and long-term depression and to reverse age-related impairments of ltp in the hippocampus. |
2003-07-14 |
2023-08-12 |
rat |
| Michael Spedding, Isabelle Neau, Laszlo Harsin. Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy. Current opinion in pharmacology. vol 3. issue 1. 2003-07-01. PMID:12550739. |
recent advances have been made in understanding the changes in neuronal plasticity in psychiatric disease at the molecular level (changes in neurotransmission, long-term potentiation, long-term depression, glutamate receptors, synaptic strength and neurotrophic support) and the systems level (changes in hippocampal, frontal and amygdala function in health and disease and the impact of stress on the hippocampal/frontal axis), as well as in the impact of drugs and sites of action for therapeutic intervention. |
2003-07-01 |
2023-08-12 |
Not clear |
| Mark F Bea. Bidirectional synaptic plasticity: from theory to reality. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 358. issue 1432. 2003-06-20. PMID:12740110. |
i give a personal account of how testing the validity of these assumptions eventually led to a detailed understanding of long-term depression and metaplasticity in hippocampal area ca1 and the visual cortex. |
2003-06-20 |
2023-08-12 |
Not clear |
| Vivien Chevaleyre, Pablo E Castill. Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability. Neuron. vol 38. issue 3. 2003-06-10. PMID:12741992. |
we describe here a form of activity-dependent long-term depression at hippocampal inhibitory synapses that is triggered postsynaptically via glutamate receptor activation but is expressed presynaptically. |
2003-06-10 |
2023-08-12 |
Not clear |
| Patrick J G H Kamphuis, Fabrizio Gardoni, Amer Kamal, Gerda Croiset, Joost M Bakker, Flaminio Cattabeni, Willem Hendrik Gispen, Frank van Bel, Monica Di Luca, Victor M Wiegan. Long-lasting effects of neonatal dexamethasone treatment on spatial learning and hippocampal synaptic plasticity: involvement of the NMDA receptor complex. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12626441. |
in hippocampal slices of dex rats, long-term depression was facilitated and potentiation was impaired. |
2003-06-02 |
2023-08-12 |
rat |
| A Whitehead, M I Rabinovich, R Huerta, V P Zhigulin, Henry D I Abarbane. Dynamical synaptic plasticity: a model and connection to some experiments. Biological cybernetics. vol 88. issue 3. 2003-05-30. PMID:12647230. |
we show that the model is quantitatively consistent with their experimental protocols producing long-term potentiation (ltp) and long-term depression (ltd) in slice preparations of rat hippocampus. |
2003-05-30 |
2023-08-12 |
rat |
| Sreedharan Sajikumar, Julietta U Fre. Anisomycin inhibits the late maintenance of long-term depression in rat hippocampal slices in vitro. Neuroscience letters. vol 338. issue 2. 2003-04-18. PMID:12566174. |
anisomycin inhibits the late maintenance of long-term depression in rat hippocampal slices in vitro. |
2003-04-18 |
2023-08-12 |
rat |