| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sreedharan Sajikumar, Julietta U Fre. Anisomycin inhibits the late maintenance of long-term depression in rat hippocampal slices in vitro. Neuroscience letters. vol 338. issue 2. 2003-04-18. PMID:12566174. |
studies were performed to investigate whether electrically-induced long-term depression (ltd) within rat hippocampal slices in vitro shares any common cellular features with ltd in the intact animal, with particular emphasis being placed on mechanisms required for its late maintenance. |
2003-04-18 |
2023-08-12 |
rat |
| Maeng-Hee Kang-Park, Meredith A Sarda, Katherine H Jones, Scott D Moore, Shirish Shenolikar, Suzanne Clark, Wilkie A Wilso. Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation. Journal of neurophysiology. vol 89. issue 2. 2003-04-04. PMID:12574446. |
these results suggest that protein phosphatase pathways are involved in the tb depotentiation similar to other type of down-regulating synaptic plasticity such as low-frequency stimulation (lfs)-induced long-term depression (ltd) and depotentiation in the rat hippocampus. |
2003-04-04 |
2023-08-12 |
rat |
| Zhiru Wang, Ning-long Xu, Chien-ping Wu, Shumin Duan, Mu-ming Po. Bidirectional changes in spatial dendritic integration accompanying long-term synaptic modifications. Neuron. vol 37. issue 3. 2003-04-04. PMID:12575953. |
in ca1 pyramidal neurons of the hippocampus, a brief period of correlated pre- and postsynaptic activity, which induces long-term potentiation (ltp) or long-term depression (ltd), results in a persistent increase or decrease in the linearity of spatial summation, respectively. |
2003-04-04 |
2023-08-12 |
Not clear |
| Linda A Santschi, Patric K Stanto. A paired-pulse facilitation analysis of long-term synaptic depression at excitatory synapses in rat hippocampal CA1 and CA3 regions. Brain research. vol 962. issue 1-2. 2003-04-01. PMID:12543458. |
in the present study, we examined the relationship between ppf and both stimulus- and chemically-evoked long-term depression of synaptic strength (ltd) at schaffer collateral-ca1, commissural/associational-ca3 and mossy fiber-ca3 synapses in rat hippocampal slices. |
2003-04-01 |
2023-08-12 |
rat |
| Hiroki Yasuda, Hideyoshi Higashi, Yoshihisa Kudo, Takafumi Inoue, Yoshio Hata, Katsuhiko Mikoshiba, Tadaharu Tsumot. Imaging of calcineurin activated by long-term depression-inducing synaptic inputs in living neurons of rat visual cortex. The European journal of neuroscience. vol 17. issue 2. 2003-03-28. PMID:12542665. |
long-term depression (ltd) of synaptic transmission is induced by low-frequency stimulation (lfs) of afferents lasting for a long time, typically for 10-15 min, in neocortical and hippocampal slices. |
2003-03-28 |
2023-08-12 |
rat |
| Shahin Akhondzadeh, Mohammad Reza Mohammadi, Ladan Kashan. Potentiation of muscimol-induced long-term depression by benzodiazepines but not zolpidem. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452540. |
the authors used the ca1 region of rat hippocampal slices to compare the effects of classic bzs, which bind equipotently to bz1 and bz2 sites, and of nonbenzodiazepine zolpidem, which binds preferentially to the bz1 sites of gaba(a) receptors, on the gaba(a)-induced long-term depression (ltd), a possible cellular mechanism for their different cognition-impairment profile. |
2003-03-26 |
2023-08-12 |
rat |
| Yuji Ikegaya, Isabelle Delcroix, Yoichiro Iwakura, Norio Matsuki, Nobuyoshi Nishiyam. Interleukin-1beta abrogates long-term depression of hippocampal CA1 synaptic transmission. Synapse (New York, N.Y.). vol 47. issue 1. 2003-03-07. PMID:12422373. |
although interleukin-1beta (il-1beta) is well known to modulate synaptic transmission and plasticity of the hippocampus, no study has yet evaluated how this cytokine affects long-term depression (ltd), one of the major forms of hippocampal synaptic plasticity. |
2003-03-07 |
2023-08-12 |
Not clear |
| I G Sil'ki. [A possible mechanism of the influence of neuromodulators and modifiable inhibition on long-term potentiation and long-term depression of excitatory inputs to main hippocampal neurons]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 52. issue 4. 2003-01-16. PMID:12391866. |
[a possible mechanism of the influence of neuromodulators and modifiable inhibition on long-term potentiation and long-term depression of excitatory inputs to main hippocampal neurons]. |
2003-01-16 |
2023-08-12 |
Not clear |
| Sang Hyoung Lee, Lidong Liu, Yu Tian Wang, Morgan Shen. Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD. Neuron. vol 36. issue 4. 2002-12-19. PMID:12441055. |
using glur2 mutants and peptide variants that dissociate nsf and ap2 interaction, we find that ap2 is involved specifically in nmda receptor-induced (but not ligand-dependent) internalization of ampa receptors, and is essential for hippocampal long-term depression (ltd). |
2002-12-19 |
2023-08-12 |
Not clear |
| Kazuhito Nakao, Yuji Ikegaya, Maki K Yamada, Nobuyoshi Nishiyama, Norio Matsuk. Hippocampal long-term depression as an index of spatial working memory. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372034. |
hippocampal long-term depression as an index of spatial working memory. |
2002-12-09 |
2023-08-12 |
rat |
| Kazuhito Nakao, Yuji Ikegaya, Maki K Yamada, Nobuyoshi Nishiyama, Norio Matsuk. Hippocampal long-term depression as an index of spatial working memory. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372034. |
long-term potentiation (ltp), a form of synaptic plasticity in the hippocampus, is a cellular model for the neural basis of learning and memory, but few studies have investigated the contribution of long-term depression (ltd), a counterpart of ltp. |
2002-12-09 |
2023-08-12 |
rat |
| Marion P Butler, Paul N Moynagh, John J O'Conno. Methods of detection of the transcription factor NF-kappa B in rat hippocampal slices. Journal of neuroscience methods. vol 119. issue 2. 2002-11-26. PMID:12323422. |
the hippocampus is one of the most studied sites for understanding the cellular and molecular mechanisms underlying long-term potentiation (ltp) and long-term depression (ltd), mechanisms believed to underlie the formation and storage of memories. |
2002-11-26 |
2023-08-12 |
rat |
| X-L Li, S Aou, Y Oomura, N Hori, K Fukunaga, T Hor. Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. Neuroscience. vol 113. issue 3. 2002-11-13. PMID:12150780. |
we investigated hippocampal long-term potentiation (ltp) and long-term depression (ltd), and the spatial-memory function in two leptin receptor-deficient rodents (zucker rats and db/db mice). |
2002-11-13 |
2023-08-12 |
mouse |
| Stanislav S Zakharenko, Leonard Zablow, Steven A Siegelbau. Altered presynaptic vesicle release and cycling during mGluR-dependent LTD. Neuron. vol 35. issue 6. 2002-10-22. PMID:12354399. |
here we used a fluorescent marker of presynaptic activity, fm 1-43, to directly image presynaptic function during metabotropic glutamate receptor-dependent long-term depression (mglur-ltd) at ca3-ca1 excitatory synapses in acute hippocampal slices. |
2002-10-22 |
2023-08-12 |
Not clear |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
to understand how neurotrophins alter this synaptic modification, we have investigated the effect of brain-derived neurotrophic factor (bdnf) on long-term depression (ltd) at schaffer collateral-ca1 synapses in rat hippocampal slices. |
2002-10-09 |
2023-08-12 |
rat |
| Michael I Daw, Zuner A Bortolotto, Emilia Saulle, Shahid Zaman, Graham L Collingridge, John T R Isaa. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nature neuroscience. vol 5. issue 9. 2002-09-27. PMID:12161757. |
phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. |
2002-09-27 |
2023-08-12 |
rat |
| Michael I Daw, Zuner A Bortolotto, Emilia Saulle, Shahid Zaman, Graham L Collingridge, John T R Isaa. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nature neuroscience. vol 5. issue 9. 2002-09-27. PMID:12161757. |
to investigate the role of phosphatidylinositol 3 kinase (pi3 kinase) in hippocampal synaptic plasticity, we used whole-cell patch clamp recordings from rat ca1 neurons to determine the effects of pi3 kinase inhibitors on long-term depression (ltd). |
2002-09-27 |
2023-08-12 |
rat |
| U Coumis, C H Davie. The effects of galanin on long-term synaptic plasticity in the CA1 area of rodent hippocampus. Neuroscience. vol 112. issue 1. 2002-09-06. PMID:12044482. |
the present study in rat and mouse hippocampal slices now demonstrates that galanin inhibits long-term potentiation induced by both tetanic and theta-burst stimulation in both apical and basal dendrites of ca1 pyramidal neurones but does not affect long-term depression. |
2002-09-06 |
2023-08-12 |
mouse |
| Guido C Faas, Hita Adwanikar, Robert W Gereau, Peter Sagga. Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177186. |
activation of group i metabotropic glutamate receptors (mglurs) can induce acute depression of excitatory synaptic transmission and long-term depression (ltd) in area ca1 of the rat hippocampus. |
2002-09-04 |
2023-08-12 |
rat |
| Lisa L Gomez, Shuvo Alam, Karen E Smith, Eric Horne, Mark L Dell'Acqu. Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177200. |
because ampa receptor pka phosphorylation and synaptic localization are regulated by similar nmda receptor-can signaling pathways linked to hippocampal long-term depression, this regulation of akap79/150 postsynaptic targeting might be important for synaptic plasticity. |
2002-09-04 |
2023-08-12 |
Not clear |