| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lifeng Zhang, Cuihong Jin, Xiaobo Lu, Jinghua Yang, Shengwen Wu, Qiufang Liu, Rong Chen, Chunyu Bai, Di Zhang, Linlin Zheng, Yanqiu Du, Yuan Ca. Aluminium chloride impairs long-term memory and downregulates cAMP-PKA-CREB signalling in rats. Toxicology. vol 323. 2014-09-26. PMID:24973631. |
this study was designed not only to observe the effects of subchronic al treatment on long-term memory and hippocampal ultrastructure but also to explore a possible underlying mechanism (involving the camp-pka-creb signalling pathway) in the hippocampus of rats.. |
2014-09-26 |
2023-08-13 |
rat |
| Lifeng Zhang, Cuihong Jin, Xiaobo Lu, Jinghua Yang, Shengwen Wu, Qiufang Liu, Rong Chen, Chunyu Bai, Di Zhang, Linlin Zheng, Yanqiu Du, Yuan Ca. Aluminium chloride impairs long-term memory and downregulates cAMP-PKA-CREB signalling in rats. Toxicology. vol 323. 2014-09-26. PMID:24973631. |
these results indicated that al may induce long-term memory damage in rats by inhibiting camp-pka-creb signalling and altering the synaptic and neuronal ultrastructure in the hippocampus. |
2014-09-26 |
2023-08-13 |
rat |
| Daniele Lana, Francesca Cerbai, Jacopo Di Russo, Francesca Boscaro, Ambra Giannetti, Polina Petkova-Kirova, Anna Maria Pugliese, Maria Grazia Giovannin. Hippocampal long term memory: effect of the cholinergic system on local protein synthesis. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:24076274. |
hippocampal long term memory: effect of the cholinergic system on local protein synthesis. |
2014-08-11 |
2023-08-12 |
rat |
| Daniele Lana, Francesca Cerbai, Jacopo Di Russo, Francesca Boscaro, Ambra Giannetti, Polina Petkova-Kirova, Anna Maria Pugliese, Maria Grazia Giovannin. Hippocampal long term memory: effect of the cholinergic system on local protein synthesis. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:24076274. |
we found that (1) mtor and p70s6k activation in the hippocampus were involved in long term memory formation; (2) rapa administration caused inhibition of mtor activation at 1 h and 4 h and of p70s6k activation at 4 h, and long term memory impairment at 24 h after acquisition; (3) scopolamine treatment caused short but not long term memory impairment with an early increase of mtor/p70s6k activation at 1 h followed by stabilization at longer times; (4) mecamylamine plus scopolamine treatment caused short term memory impairment at 1 h and 4 h and reduced the scopolamine-induced increase of mtor/p70s6k activation at 1 h and 4 h; (5) mecamylamine plus scopolamine treatment did not impair long term memory formation; (6) in vitro treatment with carbachol activated mtor and p70s6k and this effect was blocked by scopolamine and mecamylamine. |
2014-08-11 |
2023-08-12 |
rat |
| Lynn Nadel, Mary A Peterso. The hippocampus: part of an interactive posterior representational system spanning perceptual and memorial systems. Journal of experimental psychology. General. vol 142. issue 4. 2014-08-01. PMID:23895347. |
the hippocampus has frequently been viewed as a core long-term memory structure, separate from brain structures mediating other cognitive functions such as working memory and perception. |
2014-08-01 |
2023-08-12 |
Not clear |
| Florian Fiebig, Anders Lansne. Memory consolidation from seconds to weeks: a three-stage neural network model with autonomous reinstatement dynamics. Frontiers in computational neuroscience. vol 8. 2014-07-29. PMID:25071536. |
the observation of temporally graded retrograde amnesia (ra) following hippocampal lesions points to a gradual transfer of memory from hippocampus to neocortical long-term memory. |
2014-07-29 |
2023-08-13 |
Not clear |
| R Ya Gordon, M V Kapralova, O V Godukhin, V I Arkhipo. Memory disorders in rats after impairment of the dorsal hippocampal CA3 field with kainic acid. Bulletin of experimental biology and medicine. vol 155. issue 6. 2014-07-22. PMID:24288771. |
it was hypothesized that memory dysfunctions in animals after damage to the dorsal hippocampal ca3 field and to the hippocampus in general are determined by impaired transition of short-term into long-term memory. |
2014-07-22 |
2023-08-12 |
rat |
| Wan-Xia Xiong, Guo-Xia Zhou, Bei Wang, Zhang-Gang Xue, Lu Wang, Hui-Chuan Sun, Sheng-Jin G. Impaired spatial learning and memory after sevoflurane-nitrous oxide anesthesia in aged rats is associated with down-regulated cAMP/CREB signaling. PloS one. vol 8. issue 11. 2014-07-11. PMID:24260214. |
neurocognitive deficits arising from anesthetic exposure have recently been debated, while studies have shown that the phosphorylation of cyclic amp response element-binding protein (creb) in the hippocampus is critical for long-term memory. |
2014-07-11 |
2023-08-12 |
rat |
| Soyun Kim, Grégoire Borst, William L Thompson, Ramona O Hopkins, Stephen M Kosslyn, Larry R Squir. Sparing of spatial mental imagery in patients with hippocampal lesions. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 11. 2014-05-01. PMID:24136183. |
the findings suggest that the hippocampus is not needed for constructing many forms of spatial imagery but is needed for the formation of long-term memory. |
2014-05-01 |
2023-08-12 |
Not clear |
| Andrew P Yonelina. The hippocampus supports high-resolution binding in the service of perception, working memory and long-term memory. Behavioural brain research. vol 254. 2014-02-24. PMID:23721964. |
the hippocampus supports high-resolution binding in the service of perception, working memory and long-term memory. |
2014-02-24 |
2023-08-12 |
Not clear |
| Robert K Lech, Boris Sucha. The medial temporal lobe: memory and beyond. Behavioural brain research. vol 254. 2014-02-24. PMID:23769999. |
the structures of the medial temporal lobe, e.g., the hippocampus, entorhinal cortex, perirhinal cortex, and parahippocampal cortex, are known to be essential for long-term memory processing and hence are labeled the medial temporal lobe memory system. |
2014-02-24 |
2023-08-12 |
Not clear |
| Clarice Krás Borges da Silveira, Cristiane R G Furini, Fernando Benetti, Siomara da Cruz Monteiro, Ivan Izquierd. The role of histamine receptors in the consolidation of object recognition memory. Neurobiology of learning and memory. vol 103. 2014-01-24. PMID:23583502. |
when infused in the ca1 region immediately, 30, 120 or 360 min posttraining, the h1-receptor antagonist, pyrilamine, the h2-receptor antagonist, ranitidine, and the h3-receptor agonist, imetit, blocked long-term memory retention in a time dependent manner (30-120 min) without affecting general exploratory behavior, anxiety state or hippocampal function. |
2014-01-24 |
2023-08-12 |
rat |
| David Yoh von Allmen, Karoline Wurmitzer, Ernst Martin, Peter Klave. Neural activity in the hippocampus predicts individual visual short-term memory capacity. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23519991. |
although the hippocampus had been traditionally thought to be exclusively involved in long-term memory, recent studies raised controversial explanations why hippocampal activity emerged during short-term memory tasks. |
2014-01-23 |
2023-08-12 |
Not clear |
| Roger J Mullins, Su Xu, Edna F R Pereira, Jacek Mamczarz, Edson X Albuquerque, Rao P Gullapall. Delayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy study. Neurotoxicology. vol 36. 2014-01-13. PMID:23411083. |
the present results indicate that a single sub-lethal exposure of prepubertal guinea pigs to the organophosphorus pesticide chlorpyrifos can lead to long-term memory deficits that are accompanied by significant reductions in the levels of hippocampal myo-inositol. |
2014-01-13 |
2023-08-12 |
Not clear |
| Munder Zagaar, An Dao, Amber Levine, Ibrahim Alhaider, Karim Alkadh. Regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the CA1 area of the hippocampus. Sleep. vol 36. issue 5. 2014-01-09. PMID:23633758. |
regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the ca1 area of the hippocampus. |
2014-01-09 |
2023-08-12 |
Not clear |
| Munder Zagaar, An Dao, Amber Levine, Ibrahim Alhaider, Karim Alkadh. Regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the CA1 area of the hippocampus. Sleep. vol 36. issue 5. 2014-01-09. PMID:23633758. |
the present study aimed to investigate the effects of treadmill exercise on sleep deprivation (s-d)-induced impairment of hippocampal dependent long-term memory, late phase long-term potentiation (l-ltp) and its signaling cascade in the cornu ammonis 1 (ca1) area. |
2014-01-09 |
2023-08-12 |
Not clear |
| Ditte Z Christensen, Morten S Thomsen, Jens D Mikkelse. Reduced basal and novelty-induced levels of activity-regulated cytoskeleton associated protein (Arc) and c-Fos mRNA in the cerebral cortex and hippocampus of APPswe/PS1ΔE9 transgenic mice. Neurochemistry international. vol 63. issue 1. 2013-12-27. PMID:23598246. |
activity-regulated cytoskeletal-associated protein (arc) and c-fos are immediate early gene (ieg) products induced by novelty in the hippocampus and involved in the consolidation of synaptic plasticity and long-term memory. |
2013-12-27 |
2023-08-12 |
mouse |
| Robert Siman, Yin-Guo Lin, Gauri Malthankar-Phatak, Yina Don. A rapid gene delivery-based mouse model for early-stage Alzheimer disease-type tauopathy. Journal of neuropathology and experimental neurology. vol 72. issue 11. 2013-12-17. PMID:24128676. |
the perforant pathway projection from the entorhinal cortex (ec) to the hippocampal dentate gyrus is critically important for long-term memory and develops tau and amyloid pathologies and progressive degeneration starting in the early stages of alzheimer disease (ad). |
2013-12-17 |
2023-08-12 |
mouse |
| Fiorenza Stagni, Jacopo Magistretti, Sandra Guidi, Elisabetta Ciani, Chiara Mangano, Laura Calzà, Renata Bartesagh. Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome. PloS one. vol 8. issue 4. 2013-11-11. PMID:23620781. |
impairment of hippocampus-dependent long-term memory in ds appears to be related to anatomo-functional alterations of the hippocampal trisynaptic circuit formed by the dentate gyrus (dg) granule cells - ca3 pyramidal neurons - ca1 pyramidal neurons. |
2013-11-11 |
2023-08-12 |
mouse |
| Michael J Hylin, Sara A Orsi, Anthony N Moore, Pramod K Das. Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 5. 2013-10-29. PMID:23592037. |
in addition to the hippocampus, plasticity in the medial prefrontal cortex (mpfc) has been demonstrated to be critical for the storage of long-term memory, particularly memories for temporally separated events. |
2013-10-29 |
2023-08-12 |
Not clear |