| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Huang, Ping Jun Zhu, Shixing Zhang, Hongyi Zhou, Loredana Stoica, Mauricio Galiano, Krešimir Krnjević, Gregg Roman, Mauro Costa-Mattiol. mTORC2 controls actin polymerization required for consolidation of long-term memory. Nature neuroscience. vol 16. issue 4. 2013-05-21. PMID:23455608. |
actin polymerization was reduced in the hippocampus of mtorc2-deficient mice and its restoration rescued both l-ltp and ltm. |
2013-05-21 |
2023-08-12 |
mouse |
| Ilga Misane, Ayla Kruis, Anton W Pieneman, Sven Ove Ögren, Oliver Stied. GABA(A) receptor activation in the CA1 area of the dorsal hippocampus impairs consolidation of conditioned contextual fear in C57BL/6J mice. Behavioural brain research. vol 238. 2013-05-17. PMID:23098796. |
these results demonstrated that gaba(a) receptor activation in the ca1 area of the dorsal hippocampus causes a long-term memory impairment of conditioned context-dependent fear mediated by a long-lasting (≥6 h) muscimol action most likely affecting consolidation processes. |
2013-05-17 |
2023-08-12 |
mouse |
| Susan E McNulty, Ruth M Barrett, Annie Vogel-Ciernia, Melissa Malvaez, Nicole Hernandez, M Felicia Davatolhagh, Dina P Matheos, Aaron Schiffman, Marcelo A Woo. Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 12. 2013-05-07. PMID:23161447. |
indeed, their roles in these different types of long-term memory may be dependent on their expression in the brain, as nr4a2 was found to be expressed in hippocampal neurons (associated with object location memory) as well as in the insular and perirhinal cortex (associated with object recognition memory), whereas nr4a1 showed minimal neuronal expression in these cortical areas. |
2013-05-07 |
2023-08-12 |
Not clear |
| Cynthia Katche, Andrea Goldin, Carolina Gonzalez, Pedro Bekinschtein, Jorge H Medin. Maintenance of long-term memory storage is dependent on late posttraining Egr-1 expression. Neurobiology of learning and memory. vol 98. issue 3. 2013-04-30. PMID:22906840. |
local infusion of antisense oligodeoxynucleotide (aso) to specifically knockdown egr-1 in the dorsal hippocampus 8 h posttraining impairs ltm tested 7 days, but not 1 day after training, indicating that a delayed learning-associated expression of egr-1 is necessary for the persistence of ltm storage. |
2013-04-30 |
2023-08-12 |
rat |
| Cynthia Katche, Andrea Goldin, Carolina Gonzalez, Pedro Bekinschtein, Jorge H Medin. Maintenance of long-term memory storage is dependent on late posttraining Egr-1 expression. Neurobiology of learning and memory. vol 98. issue 3. 2013-04-30. PMID:22906840. |
our findings demonstrate that there are at least two waves of egr-1 expression in the dorsal hippocampus after ia training, an early wave which is involved in ia ltm formation, and a lasting late wave that peaks around 12-24 h after a strong training protocol which is specifically involved in the maintenance of ltm storage. |
2013-04-30 |
2023-08-12 |
rat |
| Heiko C Bergmann, Mark Rijpkema, Guillén Fernández, Roy P C Kessel. Distinct neural correlates of associative working memory and long-term memory encoding in the medial temporal lobe. NeuroImage. vol 63. issue 2. 2013-04-18. PMID:22484305. |
increasing evidence suggests a role for the hippocampus not only in long-term memory (ltm) but also in relational working memory (wm) processes, challenging the view of the hippocampus as being solely involved in episodic ltm. |
2013-04-18 |
2023-08-12 |
human |
| Heiko C Bergmann, Mark Rijpkema, Guillén Fernández, Roy P C Kessel. Distinct neural correlates of associative working memory and long-term memory encoding in the medial temporal lobe. NeuroImage. vol 63. issue 2. 2013-04-18. PMID:22484305. |
however, hippocampal involvement reported in some neuroimaging studies using "classical" wm tasks may at least partly reflect incidental ltm encoding. |
2013-04-18 |
2023-08-12 |
human |
| Heiko C Bergmann, Mark Rijpkema, Guillén Fernández, Roy P C Kessel. Distinct neural correlates of associative working memory and long-term memory encoding in the medial temporal lobe. NeuroImage. vol 63. issue 2. 2013-04-18. PMID:22484305. |
the right anterior hippocampus and left inferior frontal gyrus, in contrast, predicted successful ltm for pairs that were previously correctly classified in the wm task. |
2013-04-18 |
2023-08-12 |
human |
| Heiko C Bergmann, Mark Rijpkema, Guillén Fernández, Roy P C Kessel. Distinct neural correlates of associative working memory and long-term memory encoding in the medial temporal lobe. NeuroImage. vol 63. issue 2. 2013-04-18. PMID:22484305. |
our results suggest that brain regions associated with higher-level visuo-perceptual processing are involved in successful associative wm encoding, whereas the anterior hippocampus and left inferior frontal gyrus are involved in successful ltm formation during incidental encoding. |
2013-04-18 |
2023-08-12 |
human |
| Charlotte K Callaghan, Áine M Kell. Differential BDNF signaling in dentate gyrus and perirhinal cortex during consolidation of recognition memory in the rat. Hippocampus. vol 22. issue 11. 2013-04-11. PMID:22573708. |
consolidation of long-term memory is dependent on synthesis of new proteins in the hippocampus and associated cortical regions. |
2013-04-11 |
2023-08-12 |
rat |
| Alejandra Huerta-Rivas, Carolina López-Rubalcava, Sinthia L Sánchez-Serrano, Mariana Valdez-Tapia, Mónica Lamas, Silvia L Cru. Toluene impairs learning and memory, has antinociceptive effects, and modifies histone acetylation in the dentate gyrus of adolescent and adult rats. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22497993. |
in conclusion, this work provides evidence of toluene-induced impairment on learning, short- and long-term memory in adolescent and young adult rats, and shows that even a single toluene exposure can induce epigenetic modifications in the rat hippocampus. |
2013-03-14 |
2023-08-12 |
rat |
| A Gomez, S Rousset, A Charnalle. Spatial deficits in an amnesic patient with hippocampal damage: questioning the multiple trace theory. Hippocampus. vol 22. issue 6. 2013-03-11. PMID:21805527. |
furthermore, the co-occurrence of deficits in episodic long-term memory and short-term egocentric-updating representation without any short-term allocentric deficit suggests a new link between the mnemonic and navigational roles of the hippocampus. |
2013-03-11 |
2023-08-12 |
human |
| Robbert Havekes, David A Canton, Alan J Park, Ted Huang, Ting Nie, Jonathan P Day, Leonardo A Guercio, Quinn Grimes, Vincent Luczak, Irwin H Gelman, George S Baillie, John D Scott, Ted Abe. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238728. |
here, we show that mice lacking the α-isoform of gravin have deficits in pka-dependent long-lasting forms of hippocampal synaptic plasticity including β2-adrenergic receptor-mediated plasticity, and selective impairments of long-term memory storage. |
2013-02-27 |
2023-08-12 |
mouse |
| Cássia Sallaberry, Fernanda Nunes, Marcelo S Costa, Gabriela T Fioreze, Ana Paula Ardais, Paulo Henrique S Botton, Bruno Klaudat, Thomás Forte, Diogo O Souza, Elaine Elisabetsky, Lisiane O Porciúncul. Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats. Neuropharmacology. vol 64. 2013-02-11. PMID:22841916. |
because brain-derived neurotrophic factor (bdnf) is associated with memory formation and bdnf's actions are modulated by adenosine receptors, the molecular targets for the psychostimulant actions of caffeine, we here compare the effects of chronic caffeine (1 mg/ml drinking solution for 30 days) on short- and long term memory and on levels of hippocampal probdnf, mature bdnf, trkb and creb in young (3 month old) and middle-aged (12 month old) rats. |
2013-02-11 |
2023-08-12 |
rat |
| Yudong Yao, Charles Shao, Desingarao Jothianandan, Andrew Tcherepanov, Harel Shouval, Todd Charlton Sackto. Matching biochemical and functional efficacies confirm ZIP as a potent competitive inhibitor of PKMζ in neurons. Neuropharmacology. vol 64. 2013-02-11. PMID:22846225. |
the myristoylated ζ-pseudosubstrate peptide, zip, potently inhibits pkmζ biochemically in vitro, within cultured cells, and within neurons in hippocampal slices, and reverses ltp maintenance and erases long-term memory storage. |
2013-02-11 |
2023-08-12 |
Not clear |
| Li Zhang, Yan-Hai Li, Kai Meng, Wen Xi. [The expressions of AMPAR/GluR2 in hippocampal CA1 area of rats before and after late-phase long-term potentiation reversal]. Sheng li xue bao : [Acta physiologica Sinica]. vol 62. issue 1. 2013-01-24. PMID:20179884. |
late-phase long-term potentiation (l-ltp) plays a very important role in the maintenance of long-term memory in hippocampus. |
2013-01-24 |
2023-08-12 |
rat |
| Jeremy M Barry, Bruno Rivard, Steven E Fox, Andre A Fenton, Todd C Sacktor, Robert U Mulle. Inhibition of protein kinase Mζ disrupts the stable spatial discharge of hippocampal place cells in a familiar environment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 40. 2013-01-17. PMID:23035087. |
it is not known, however, if map stability requires persistent hippocampal synaptic strength changes that are vulnerable to blockade of protein kinase mζ (pkmζ) phosphorylation activity, a manipulation that reverses hippocampal ltp and disrupts multiple forms of long-term memory. |
2013-01-17 |
2023-08-12 |
rat |
| María Cecilia Martínez, Nadia Alen, Fabricio Ballarini, Diego Moncada, Haydée Viol. Memory traces compete under regimes of limited Arc protein synthesis: implications for memory interference. Neurobiology of learning and memory. vol 98. issue 2. 2013-01-09. PMID:22683463. |
furthermore, infusing arc antisense oligonucleotide into the dorsal hippocampus, we found that arc is necessary for ltm formation of these two types of learning tasks and is one of the prps that can be shared between them when animals are trained in both of and ia. |
2013-01-09 |
2023-08-12 |
rat |
| Katherine R Martin, Alicia Corlett, Daphne Dubach, Tomris Mustafa, Harold A Coleman, Helena C Parkington, Tobias D Merson, James A Bourne, Sílvia Porta, Maria L Arbonés, David I Finkelstein, Melanie A Pritchar. Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory. Human molecular genetics. vol 21. issue 13. 2012-12-13. PMID:22511596. |
deficits in hippocampal-dependent learning and short- and long-term memory are accompanied by a failure to maintain long-term potentiation (ltp) in hippocampal slices. |
2012-12-13 |
2023-08-12 |
mouse |
| Vânia K M Moojen, Marcela Damiani-Neves, Daniela V Bavaresco, Bruna B Pescador, Clarissa M Comim, João Quevedo, Carina R Boec. NMDA preconditioning prevents object recognition memory impairment and increases brain viability in mice exposed to traumatic brain injury. Brain research. vol 1466. 2012-11-20. PMID:22652305. |
in conclusion, nmda preconditioning induced impairment of the long-term memory; however, it was able to protect against the novel recognition memory impairment and increase the cellular survival in the hippocampus of mice exposed to traumatic brain injury. |
2012-11-20 |
2023-08-12 |
mouse |