| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David M Cole, Nicole Y L Oei, Roelof P Soeter, Stephanie Both, Joop M A van Gerven, Serge A R B Rombouts, Christian F Beckman. Dopamine-dependent architecture of cortico-subcortical network connectivity. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 7. 2014-01-07. PMID:22645252. |
maladaptive dopaminergic mediation of reward processing in humans is thought to underlie multiple neuropsychiatric disorders, including addiction, parkinson's disease, and schizophrenia. |
2014-01-07 |
2023-08-12 |
human |
| Kathy Burton Avsar, Rosalyn Eve Weller, James Edward Cox, Meredith Amanda Reid, David Matthew White, Adrienne Carol Laht. An fMRI investigation of delay discounting in patients with schizophrenia. Brain and behavior. vol 3. issue 4. 2014-01-01. PMID:24381810. |
these results point to disruption of several neural networks during decision making, including the executive, reward, default mode, and emotional networks, and suggest processes that are impaired during decision making in schizophrenia. |
2014-01-01 |
2023-08-12 |
human |
| T Katayama, M Okamoto, Y Suzuki, K-Y Hoshino, E Jod. Phencyclidine affects firing activity of ventral tegmental area neurons that are related to reward and social behaviors in rats. Neuroscience. vol 240. 2013-11-13. PMID:23458711. |
patients with schizophrenia exhibit deficits in motivation and affect, which suggests an impairment in the reward system. |
2013-11-13 |
2023-08-12 |
rat |
| T Katayama, M Okamoto, Y Suzuki, K-Y Hoshino, E Jod. Phencyclidine affects firing activity of ventral tegmental area neurons that are related to reward and social behaviors in rats. Neuroscience. vol 240. 2013-11-13. PMID:23458711. |
disruption of the response of vta neurons to reward stimuli and socially interactive situations may be involved in pcp-induced impairments similar to the negative symptoms of schizophrenia. |
2013-11-13 |
2023-08-12 |
rat |
| Anne-Marie Bédard, Jérôme Maheux, Daniel Lévesque, Anne-Noël Samah. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. Schizophrenia bulletin. vol 39. issue 3. 2013-10-28. PMID:22927669. |
prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. |
2013-10-28 |
2023-08-12 |
rat |
| James A Waltz, Zuzana Kasanova, Thomas J Ross, Betty J Salmeron, Robert P McMahon, James M Gold, Elliot A Stei. The roles of reward, default, and executive control networks in set-shifting impairments in schizophrenia. PloS one. vol 8. issue 2. 2013-09-10. PMID:23468948. |
the roles of reward, default, and executive control networks in set-shifting impairments in schizophrenia. |
2013-09-10 |
2023-08-12 |
human |
| James A Waltz, Zuzana Kasanova, Thomas J Ross, Betty J Salmeron, Robert P McMahon, James M Gold, Elliot A Stei. The roles of reward, default, and executive control networks in set-shifting impairments in schizophrenia. PloS one. vol 8. issue 2. 2013-09-10. PMID:23468948. |
these findings suggest that schizophrenia is associated with a reduced ability to deactivate components of default mode networks, following the presentation of informative feedback and that motivational deficits in sz relate closely to feedback-evoked activity in reward circuit components. |
2013-09-10 |
2023-08-12 |
human |
| Dean S Carson, Adam J Guastella, Emily R Taylor, Iain S McGrego. A brief history of oxytocin and its role in modulating psychostimulant effects. Journal of psychopharmacology (Oxford, England). vol 27. issue 3. 2013-08-16. PMID:23348754. |
oxytocin is now implicated in an extensive range of psychological phenomena including reward and memory processes and has been investigated as a treatment for several psychiatric disorders including addiction, anxiety, autism, and schizophrenia. |
2013-08-16 |
2023-08-12 |
Not clear |
| F Woodward Hopf, Taban Seif, Shinjae Chung, Olivier Civell. MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro. PeerJ. vol 1. 2013-05-07. PMID:23646281. |
the mch and dopamine receptor systems have been shown to modulate a number of behaviors related to reward processing, addiction, and neuropsychiatric conditions such as schizophrenia and depression. |
2013-05-07 |
2023-08-12 |
Not clear |
| Mette Odegaard Nielsen, Egill Rostrup, Sanne Wulff, Nikolaj Bak, Brian Villumsen Broberg, Henrik Lublin, Shitij Kapur, Birte Glentho. Improvement of brain reward abnormalities by antipsychotic monotherapy in schizophrenia. Archives of general psychiatry. vol 69. issue 12. 2013-02-12. PMID:22868877. |
improvement of brain reward abnormalities by antipsychotic monotherapy in schizophrenia. |
2013-02-12 |
2023-08-12 |
human |
| Georg Juckel, Eva Friedel, Michael Koslowski, Henning Witthaus, Seza Ozgürdal, Yehonala Gudlowski, Brian Knutson, Jana Wrase, Martin Brüne, Andreas Heinz, Florian Schlagenhau. Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia. Neuropsychobiology. vol 66. issue 1. 2012-11-27. PMID:22797277. |
ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia. |
2012-11-27 |
2023-08-12 |
human |
| Georg Juckel, Eva Friedel, Michael Koslowski, Henning Witthaus, Seza Ozgürdal, Yehonala Gudlowski, Brian Knutson, Jana Wrase, Martin Brüne, Andreas Heinz, Florian Schlagenhau. Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia. Neuropsychobiology. vol 66. issue 1. 2012-11-27. PMID:22797277. |
early dysfunction of the brain reward system in schizophrenia might be already recognized in the prodromal phase of this illness. |
2012-11-27 |
2023-08-12 |
human |
| Mark A Ungless, Anthony A Grac. Are you or aren't you? Challenges associated with physiologically identifying dopamine neurons. Trends in neurosciences. vol 35. issue 7. 2012-11-12. PMID:22459161. |
the dopamine system is involved in motivation, reward and learning, and dysfunction in this system has been implicated in several disorders, including parkinson's disease (pd) and schizophrenia. |
2012-11-12 |
2023-08-12 |
Not clear |
| A George Awa. Is it time to consider comorbid substance abuse as a new indication for antipsychotic drug development? Journal of psychopharmacology (Oxford, England). vol 26. issue 7. 2012-10-22. PMID:22170735. |
abnormalities in hippocampal/cortical function in schizophrenia which mediate reward and reinforcement behavior are identified as central to the development and maintenance of comorbid addictive states. |
2012-10-22 |
2023-08-12 |
Not clear |
| Joëlle Desfossés, Emmanuel Stip, Lahcen Ait Bentaleb, Olivier Lipp, Jean-Pierre Chiasson, Alexandra Furtos, Karine Venne, Edouard Kouassi, Stéphane Potvi. Plasma Endocannabinoid Alterations in Individuals with Substance Use Disorder are Dependent on the "Mirror Effect" of Schizophrenia. Frontiers in psychiatry. vol 3. 2012-10-12. PMID:23055987. |
theoretically, schizophrenia and sud may share endocannabinoid alterations in the brain reward system. |
2012-10-12 |
2023-08-12 |
Not clear |
| Daniel H Wolf, Raphaelt Gerraty, Theodore D Satterthwaite, James Loughead, Timothy Campellone, Mark A Elliott, Bruce I Turetsky, Ruben C Gur, Raquel E Gu. Striatal intrinsic reinforcement signals during recognition memory: relationship to response bias and dysregulation in schizophrenia. Frontiers in behavioral neuroscience. vol 5. 2012-10-02. PMID:22355285. |
these findings highlight the importance of accounting for intrinsic motivation and reward when studying cognitive tasks, and add to growing evidence of reward circuit dysfunction in schizophrenia that may impact cognition and function. |
2012-10-02 |
2023-08-12 |
human |
| Ryan D Ward, Eleanor H Simpson, Vanessa L Richards, Gita Deo, Kathleen Taylor, John I Glendinning, Eric R Kandel, Peter D Balsa. Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414818. |
dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. |
2012-09-21 |
2023-08-12 |
mouse |
| Ryan D Ward, Eleanor H Simpson, Vanessa L Richards, Gita Deo, Kathleen Taylor, John I Glendinning, Eric R Kandel, Peter D Balsa. Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414818. |
these results demonstrate for the first time in a transgenic animal model of schizophrenia a dissociation between hedonic reaction to reward and incentive motivation, and show a striking parallel to the proposed neurobiological and psychological mechanisms of impaired incentive motivation in schizophrenia. |
2012-09-21 |
2023-08-12 |
mouse |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
reward processing abnormalities have been implicated in the pathophysiology of negative symptoms such as anhedonia and avolition in schizophrenia. |
2012-09-10 |
2023-08-12 |
human |
| Mette Ødegaard Nielsen, Egill Rostrup, Sanne Wulff, Nikolaj Bak, Henrik Lublin, Shitij Kapur, Birte Glenthø. Alterations of the brain reward system in antipsychotic naïve schizophrenia patients. Biological psychiatry. vol 71. issue 10. 2012-08-28. PMID:22418013. |
alterations of the brain reward system in antipsychotic naïve schizophrenia patients. |
2012-08-28 |
2023-08-12 |
Not clear |