| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allen E Thornton, Vanessa G Boudreau, Stephanie Y Griffiths, Todd S Woodward, Tanya Fawkes-Kirby, William G Hone. The impact of monetary reward on memory in schizophrenia spectrum disorder. Neuropsychology. vol 21. issue 5. 2007-11-28. PMID:17784811. |
although healthy individuals benefited from reward at a high vwm load level, schizophrenia patients exhibited no reward-related improvements in vwm. |
2007-11-28 |
2023-08-12 |
human |
| P Kirsch, S Ronshausen, D Mier, B Gallhofe. The influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients. Pharmacopsychiatry. vol 40. issue 5. 2007-11-20. PMID:17874350. |
the influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients. |
2007-11-20 |
2023-08-12 |
Not clear |
| Alan I Gree. Pharmacotherapy for schizophrenia and co-occurring substance use disorders. Neurotoxicity research. vol 11. issue 1. 2007-05-22. PMID:17449446. |
our group has suggested that the brain reward circuit dysfunction model, which may incorporate aspects of all of these models, may help direct research aimed at developing new pharmacological treatments for patients with schizophrenia and co-occurring sud. |
2007-05-22 |
2023-08-12 |
Not clear |
| Joseph T Coyl. Substance use disorders and Schizophrenia: a question of shared glutamatergic mechanisms. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197372. |
given the role of nmda receptors in the reward circuitry and in substance dependence, it is reasonable to speculate that nmda receptor dysfunction is a shared pathologic process in schizophrenia and co-morbid suds. |
2007-03-20 |
2023-08-12 |
human |
| John H Krystal, D Cyril D'Souza, Jürgen Gallinat, Naomi Driesen, Anissa Abi-Dargham, Ismene Petrakis, Andreas Heinz, Godfrey Pearlso. The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197373. |
the distortions in reward processing and altered response to substances of abuse also increase the likelihood that individuals with schizophrenia will self-medicate their subjective distress with abused substances. |
2007-03-20 |
2023-08-12 |
Not clear |
| Alan I Green, E Sherwood Brow. Comorbid schizophrenia and substance abuse. The Journal of clinical psychiatry. vol 67. issue 9. 2007-02-23. PMID:17081075. |
a brief discussion about the neurobiology of schizophrenia explains how schizophrenia may create a biologic predisposition to substance abuse by altering the brain reward system. |
2007-02-23 |
2023-08-12 |
Not clear |
| Georg Juckel, Florian Schlagenhauf, Michael Koslowski, Dimitri Filonov, Torsten Wüstenberg, Arno Villringer, Brian Knutson, Thorsten Kienast, Jürgen Gallinat, Jana Wrase, Andreas Hein. Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics. Psychopharmacology. vol 187. issue 2. 2006-12-22. PMID:16721614. |
dysfunction of the dopaminergic reward system may contribute to negative symptoms in schizophrenia. |
2006-12-22 |
2023-08-12 |
Not clear |
| Igor Elman, David Borsook, Scott E Luka. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16541087. |
food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. |
2006-11-01 |
2023-08-12 |
Not clear |
| Igor Elman, David Borsook, Scott E Luka. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16541087. |
here, we propose a mechanism based on brain reward function, a relevant etiologic factor in both schizophrenia and overeating. |
2006-11-01 |
2023-08-12 |
Not clear |
| Cecilia Gotti, Michele Zoli, Francesco Clement. Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends in pharmacological sciences. vol 27. issue 9. 2006-10-26. PMID:16876883. |
these channels are involved both in physiological functions (including cognition, reward, motor activity and analgesia) and in pathological conditions such as alzheimer's disease, parkinson's disease, some forms of epilepsy, depression, autism and schizophrenia. |
2006-10-26 |
2023-08-12 |
Not clear |
| Alan I Gree. Treatment of schizophrenia and comorbid substance abuse: pharmacologic approaches. The Journal of clinical psychiatry. vol 67 Suppl 7. 2006-09-19. PMID:16961422. |
our group and others have advanced a neurobiological hypothesis to explain this comorbidity-that a mesocorticolimbic brain reward circuit underlies the substance use disorder in patients with schizophrenia. |
2006-09-19 |
2023-08-12 |
Not clear |
| Andrew Smith, Ming Li, Sue Becker, Shitij Kapu. Dopamine, prediction error and associative learning: a model-based account. Network (Bristol, England). vol 17. issue 1. 2006-06-28. PMID:16613795. |
our departure from model-free reinforcement learning also offers: 1) a parsimonious distinction between tonic and phasic dopamine functions; 2) a potential generalization of the role of phasic dopamine from valence-dependent "reward" processing to valence-independent "salience" processing; 3) an explanation for the selectivity of certain dopamine manipulations on motivation for distal rewards; and 4) a plausible link between formal notions of prediction error and accounts of disturbances of thought in schizophrenia (in which dopamine dysfunction is strongly implicated). |
2006-06-28 |
2023-08-12 |
Not clear |
| Georg Juckel, Florian Schlagenhauf, Michael Koslowski, Torsten Wüstenberg, Arno Villringer, Brian Knutson, Jana Wrase, Andreas Hein. Dysfunction of ventral striatal reward prediction in schizophrenia. NeuroImage. vol 29. issue 2. 2006-03-21. PMID:16139525. |
negative symptoms may be associated with dysfunction of the brain reward system in schizophrenia. |
2006-03-21 |
2023-08-12 |
Not clear |
| R L H Clements, A J Greensha. Facilitation of brain stimulation reward by MK-801 (dizocilpine) may be independent of D2-like dopamine receptor stimulation in rats. Psychopharmacology. vol 182. issue 1. 2006-02-22. PMID:16133130. |
dopamine (da) and glutamate (glu) interactions in the mesocorticolimbic pathway may regulate motivation and reward and contribute to schizophrenia and drug abuse. |
2006-02-22 |
2023-08-12 |
rat |
| Ester Frid. Endocannabinoids in the central nervous system: from neuronal networks to behavior. Current drug targets. CNS and neurological disorders. vol 4. issue 6. 2006-02-07. PMID:16375681. |
however, additional functions and dysfunctions such as reward and addiction, motor coordination, pain perception, feeding and appetite, coping with stress, schizophrenia and epilepsy will also be reviewed. |
2006-02-07 |
2023-08-12 |
Not clear |
| Robert M Roth, Mary F Brunette, Alan I Gree. Treatment of substance use disorders in schizophrenia: a unifying neurobiological mechanism? Current psychiatry reports. vol 7. issue 4. 2006-01-12. PMID:16098282. |
of these, brain reward circuitry dysfunction, hypothesized to be etiologically important in suds, may be an especially salient target for treatments aimed at the reduction of substance use in patients with schizophrenia. |
2006-01-12 |
2023-08-12 |
Not clear |
| Michael Ritsner, Ehud Susse. Temperament types are associated with weak self-construct, elevated distress and emotion-oriented coping in schizophrenia: evidence for a complex vulnerability marker? Psychiatry research. vol 128. issue 3. 2005-04-15. PMID:15541778. |
we found that the harm avoidance (ha) factor was higher, while reward dependence (rd) was lower in schizophrenia patients than in healthy controls. |
2005-04-15 |
2023-08-12 |
Not clear |
| Douglas L Noordsy, Alan I Gree. Pharmacotherapy for schizophrenia and co-occurring substance use disorders. Current psychiatry reports. vol 5. issue 5. 2004-01-06. PMID:13678553. |
the confluence of findings is consistent with a model of a reward dysfunction inherent in the neuropathology of schizophrenia, leading to a heightened vulnerability of people with schizophrenia to substance use disorders. |
2004-01-06 |
2023-08-12 |
Not clear |
| Michael H Joseph, Krishna Datla, Andrew M J Youn. The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition? Neuroscience and biobehavioral reviews. vol 27. issue 6. 2003-12-18. PMID:14599434. |
psychopharmacological studies have implicated the dopaminergic innervation of the nucleus accumbens (nac) in reward and reinforcement, in the actions of addictive drugs, and in the control of the symptoms of schizophrenia. |
2003-12-18 |
2023-08-12 |
rat |
| S Potvin, E Stip, J-Y Ro. [Schizophrenia and addiction: An evaluation of the self-medication hypothesis]. L'Encephale. vol 29. issue 3 Pt 1. 2003-09-17. PMID:12876543. |
however, from a biological perspective, substance abuse among schizophrenic patients appears paradoxical: while the positive symptoms of schizophrenia might involve an hyperactivity of the reward system, the drugs of abuse all seem to increase dopamine release in that same system. |
2003-09-17 |
2023-08-12 |
Not clear |