| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sugai Liang, Yue Wu, Li Hanxiaoran, Andrew J Greenshaw, Tao L. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatric disease and treatment. vol 18. 2022-07-15. PMID:35836582. |
here, we review the characteristics of anhedonia in depression and schizophrenia as well as shared or disorder-specific anhedonia-related alterations in reward and aversion pathways of the brain. |
2022-07-15 |
2023-08-14 |
Not clear |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
diminished social motivation is a core feature of schizophrenia that might reflect disturbances in social reward processing. |
2022-06-13 |
2023-08-14 |
human |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
importantly, schizophrenia participants exhibited less anticipation of social rewards relative to nonsocial rewards (spn), whereas healthy participants showed similar anticipation for both reward types. |
2022-06-13 |
2023-08-14 |
human |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
together, these findings provide preliminary evidence for intact social reward "liking" and impaired "wanting" in schizophrenia. |
2022-06-13 |
2023-08-14 |
human |
| Alexandra Münster, Susanne Sommer, Diana Kúkeľová, Hannes Sigrist, Eliza Koros, Serena Deiana, Klaus Klinder, Tamara Baader-Pagler, Svenja Mayer-Wrangowski, Boris Ferger, Tom Bretschneider, Christopher R Pryce, Wolfgang Hauber, Moritz von Heimendah. Effects of GPR139 agonism on effort expenditure for food reward in rodent models: Evidence for pro-motivational actions. Neuropharmacology. 2022-05-13. PMID:35561791. |
apathy, deficiency of motivation including willingness to exert effort for reward, is a common symptom in many psychiatric and neurological disorders, including depression and schizophrenia. |
2022-05-13 |
2023-08-13 |
Not clear |
| Erin K Moran, Adam J Culbreth, Deanna M Barc. Anhedonia in Schizophrenia. Current topics in behavioral neurosciences. 2022-05-03. PMID:35503596. |
here we detail these mechanisms for emotional and motivational impairment in people with schizophrenia including: (1) initial response to reward; (2) reward anticipation; (3) reward learning; (4) effort-cost decision-making; (5) working memory and cognitive control. |
2022-05-03 |
2023-08-13 |
Not clear |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
spatial memory and reward processing are known to be disrupted in schizophrenia. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
since the lateral septum (ls) may play an important role in the integration of location and reward, we examined the effect of maternal immune activation (mia), a known schizophrenia risk factor, on spatial representation in the rat ls. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
these findings suggest that a schizophrenia risk factor disrupts the phase-based encoding of location-reward relationships in the ls, potentially smearing reward representations across space. |
2022-04-09 |
2023-08-13 |
rat |
| Xiaoyan Cheng, Lingling Wang, Qinyu Lv, Haisu Wu, Xinxin Huang, Jie Yuan, Xirong Sun, Xudong Zhao, Chao Yan, Zhenghui Y. Reduced learning bias towards the reward context in medication-naive first-episode schizophrenia patients. BMC psychiatry. vol 22. issue 1. 2022-02-17. PMID:35172748. |
reduced learning bias towards the reward context in medication-naive first-episode schizophrenia patients. |
2022-02-17 |
2023-08-13 |
Not clear |
| Karel Kieslich, Vincent Valton, Jonathan P Roise. Pleasure, Reward Value, Prediction Error and Anhedonia. Current topics in behavioral neurosciences. 2022-02-14. PMID:35156187. |
overall, there is reliable evidence that depression and schizophrenia are associated with disrupted reward processing. |
2022-02-14 |
2023-08-13 |
Not clear |
| Yan-Yu Wang, Yi Wang, Jia Huang, Xi-He Sun, Xi-Zhen Wang, Shu-Xian Zhang, Guo-Hui Zhu, Simon S Y Lui, Eric F C Cheung, Hong-Wei Sun, Raymond C K Cha. Shared and distinct reward neural mechanisms among patients with schizophrenia, major depressive disorder, and bipolar disorder: an effort-based functional imaging study. European archives of psychiatry and clinical neuroscience. 2022-01-26. PMID:35079855. |
unwillingness to exert effort for rewards has been found in patients with schizophrenia (scz), major depressive disorder (mdd), and bipolar disorder (bd), but the underlying shared and distinct reward neural mechanisms remain unclear. |
2022-01-26 |
2023-08-13 |
Not clear |
| Ningzhi Gou, Yizhen Xiang, Jiansong Zhou, Simei Zhang, Shaoling Zhong, Juntao Lu, Xiaoxi Liang, Jin Liu, Xiaoping Wan. Identification of violent patients with schizophrenia using a hybrid machine learning approach at the individual level. Psychiatry research. vol 306. 2021-12-07. PMID:34823086. |
in addition, the msot discriminative neuroimaging features involved in the prefrontal-temporal cognitive circuit and striatum reward system, indicating that dysfunction in cortical-subcortical circuits might be associated with high risk of violence in patients with schizophrenia. |
2021-12-07 |
2023-08-13 |
Not clear |
| Yazen Alnefeesi, Jocelyn K Tamura, Leanna M W Lui, Muhammad Youshay Jawad, Felicia Ceban, Susan Ling, Flora Nasri, Joshua D Rosenblat, Roger S McIntyr. Trace amine-associated receptor 1 (TAAR1): Potential application in mood disorders: A systematic review. Neuroscience and biobehavioral reviews. vol 131. 2021-12-03. PMID:34537265. |
available evidence indicates that the trace amine-associated receptor 1 (taar1) agonist sep-363856 is promising, as it improves measures of cognitive and reward function in schizophrenia. |
2021-12-03 |
2023-08-13 |
Not clear |
| Marek Krzystanek, Anna Warchala, Beata Trędzbor, Ewa Martyniak, Katarzyna Skałacka, Artur Pałas. Amantadine in the Treatment of Sexual Inactivity in Schizophrenia Patients Taking Atypical Antipsychotics-The Pilot Case Series Study. Pharmaceuticals (Basel, Switzerland). vol 14. issue 10. 2021-10-26. PMID:34681171. |
the mechanism of sexual dysfunction in patients treated for schizophrenia may be related to the side effects of antipsychotic drugs (hyperprolactinemia, suppression of the reward system), but it may also be related to the pathogenesis of schizophrenia itself. |
2021-10-26 |
2023-08-13 |
Not clear |
| Suzanne R Neumann, Paul Glue, Richard J Linscot. Aberrant salience and reward processing: a comparison of measures in schizophrenia and anxiety. Psychological medicine. vol 51. issue 9. 2021-10-11. PMID:32148214. |
aberrant salience and reward processing: a comparison of measures in schizophrenia and anxiety. |
2021-10-11 |
2023-08-13 |
Not clear |
| Suzanne R Neumann, Paul Glue, Richard J Linscot. Aberrant salience and reward processing: a comparison of measures in schizophrenia and anxiety. Psychological medicine. vol 51. issue 9. 2021-10-11. PMID:32148214. |
aberrant salience may contribute to the development of schizophrenia symptoms via alterations in reward processing and motivation. |
2021-10-11 |
2023-08-13 |
Not clear |
| Suzanne R Neumann, Paul Glue, Richard J Linscot. Aberrant salience and reward processing: a comparison of measures in schizophrenia and anxiety. Psychological medicine. vol 51. issue 9. 2021-10-11. PMID:32148214. |
therefore, we investigated relationships among measures of aberrant salience, reward, and motivation in schizophrenia and anxiety. |
2021-10-11 |
2023-08-13 |
Not clear |
| Kristina Schwarz, Carolin Moessnang, Janina I Schweiger, Anais Harneit, Michael Schneider, Junfang Chen, Han Cao, Emanuel Schwarz, Stephanie H Witt, Marcella Rietschel, Markus Nöthen, Franziska Degenhardt, Carolin Wackerhagen, Susanne Erk, Nina Romanczuk-Seiferth, Henrik Walter, Heike Tost, Andreas Meyer-Lindenber. Ventral Striatal-Hippocampus Coupling During Reward Processing as a Stratification Biomarker for Psychotic Disorders. Biological psychiatry. 2021-10-05. PMID:34607654. |
altered ventral striatal (vst) activation to reward expectancy is a well-established intermediate phenotype for psychiatric disorders, specifically schizophrenia (sz). |
2021-10-05 |
2023-08-13 |
human |