| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cibele Canal Castro, Aline de Souza Pagnussat, Carolina Demarchi Munhoz, Carlos Alexandre Nett. Coumestrol pre-treatment improves spatial learning and memory deficits following transient cerebral ischemia recruiting hippocampal GluR2 AMPA receptors. Hippocampus. 2022-03-29. PMID:35347795. |
this study sought to investigate the neuroprotective effect of coumestrol against spatial memory impairment induced by global ischemia that leads to neural death by reducing the glur2 receptors content in the hippocampal ca1 area. |
2022-03-29 |
2023-08-13 |
mouse |
| Bethany E Frost, Sean K Martin, Matheus Cafalchio, Md Nurul Islam, John P Aggleton, Shane M O'Mar. Anterior Thalamic Inputs Are Required for Subiculum Spatial Coding, with Associated Consequences for Hippocampal Spatial Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 30. 2021-11-22. PMID:34131030. |
we found that both permanent and reversible anterior thalamic nuclei lesions in male rats cause a cessation of subicular spatial signaling, reduce spatial memory performance to chance, but leave hippocampal ca1 place cells largely unaffected. |
2021-11-22 |
2023-08-13 |
rat |
| Gholam Hossein Meftahi, Zohreh Jangravi, Maryam Taghdir, Mojtaba Sepandi, Zahra Bahar. Micro-injection of propranolol within basolateral amygdala impaired fear and spatial memory and dysregulated evoked responses of CA1 neurons following foot shock stress in rats. Brain research bulletin. vol 177. 2021-11-18. PMID:34534638. |
micro-injection of propranolol within basolateral amygdala impaired fear and spatial memory and dysregulated evoked responses of ca1 neurons following foot shock stress in rats. |
2021-11-18 |
2023-08-13 |
rat |
| Mola Mohammadi, Homa Manaheji, Nader Maghsoudi, Samira Danyali, Mansoureh Baniasadi, Jalal Zaringhala. Microglia dependent BDNF and proBDNF can impair spatial memory performance during persistent inflammatory pain. Behavioural brain research. vol 390. 2021-10-25. PMID:32442548. |
taking together, the results of the current study for the first time revealed that an increase in the microglia dependent probdnf/bdnf ratio following persistent inflammatory pain leads to cell death of the ca1 and dg neurons that subsequently causes a cognitive deficit in the learning and spatial memory functions. |
2021-10-25 |
2023-08-13 |
rat |
| Jessica E Owen, Yan Zhu, Polina Fenik, Guanxia Zhan, Patrick Bell, Cathy Liu, Sigrid Vease. Late-in-life neurodegeneration after chronic sleep loss in young adult mice. Sleep. vol 44. issue 8. 2021-10-25. PMID:33768250. |
twelve months following css exposure, css-exposed mice evidenced reductions in ca1 neuron counts and volume, spatial memory deficits, ca1 glial activation, and loss of lcn. |
2021-10-25 |
2023-08-13 |
mouse |
| Joel E Soler, Hang Xiong, Faiez Samad, Fredric P Manfredsson, Alfred J Robison, Antonio A Núñez, Lily Ya. Orexin (hypocretin) mediates light-dependent fluctuation of hippocampal function in a diurnal rodent. Hippocampus. vol 31. issue 10. 2021-09-22. PMID:34263969. |
compared to animals housed in a 12:12 h bright light-dark (brld) cycle, grass rats kept in a 12:12 h dim light-dark (dimld) cycle showed impaired spatial memory in the morris water maze (mwm) and reduced ca1 apical dendritic spine density. |
2021-09-22 |
2023-08-13 |
rat |
| Soomaayeh Heysieattalab, Jafar Doostmohammadi, Mahgol Darvishmolla, Negin Saeedi, Narges Hosseinmardi, Masoumeh Gholami, Mahyar Janahmadi, Samira Choopan. Non-selective COX inhibitors impair memory formation and short-term but not long-term synaptic plasticity. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 9. 2021-09-02. PMID:33937935. |
spatial memory and synaptic plasticity were assessed by water maze performance and in vivo field potential recording from ca1, respectively. |
2021-09-02 |
2023-08-13 |
Not clear |
| Supriya Swarnkar, Yosef Avchalumov, Isabel Espadas, Eddie Grinman, Xin-An Liu, Bindu L Raveendra, Aya Zucca, Sonia Mediouni, Abhishek Sadhu, Susana Valente, Damon Page, Kyle Miller, Sathyanarayanan V Puthanveetti. Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. Cell reports. vol 36. issue 2. 2021-07-30. PMID:34260917. |
loss of function of kif5c in dorsal hippocampal ca1 neurons constrains both spatial and contextual fear memory, whereas gain of function specifically enhances spatial memory and extinction of contextual fear. |
2021-07-30 |
2023-08-13 |
Not clear |
| Can Dong, Antoine D Madar, Mark E J Sheffiel. Distinct place cell dynamics in CA1 and CA3 encode experience in new environments. Nature communications. vol 12. issue 1. 2021-06-01. PMID:34016996. |
these results reflect different roles in ca1 and ca3 in spatial memory processing during familiarization to new environments and constrain the potential mechanisms that support them. |
2021-06-01 |
2023-08-13 |
mouse |
| Rachael E Hokenson, Annabel K Short, Yuncai Chen, Aidan L Pham, Emily T Adams, Jessica L Bolton, Vivek Swarup, Christine M Gall, Tallie Z Bara. Unexpected Role of Physiological Estrogen in Acute Stress-Induced Memory Deficits. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 4. 2021-03-26. PMID:33262247. |
as spatial memory requires an intact dorsal hippocampal ca1, we examined synaptic integrity in mice stressed at different cycle phases and found a congruence of dendritic spine density and spatial memory deficits, with reduced spine density only in mice stressed during high estradiol cycle phases. |
2021-03-26 |
2023-08-13 |
mouse |
| Stephen D Glasgow, Edwin W Wong, Greta Thompson-Steckel, Nathalie Marcal, Philippe Séguéla, Edward S Ruthazer, Timothy E Kenned. Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus. Molecular brain. vol 13. issue 1. 2021-02-03. PMID:32264905. |
employing hippocampal subregion-specific conditional deletion of dcc, we show that dcc loss from ca1 hippocampal pyramidal neurons resulted in deficits in spatial memory, increased resting membrane potential, abnormal dendritic spine morphology, weaker spontaneous excitatory postsynaptic activity, and reduced levels of postsynaptic adaptor and signaling proteins; however, the capacity to induce ltp remained intact. |
2021-02-03 |
2023-08-13 |
mouse |
| Yingqiang Qi, Sanrong Wang, Yanmin Luo, Wei Huang, Linmu Chen, Yi Zhang, Xin Liang, Jing Tang, Yang Zhang, Lei Zhang, Fenglei Chao, Yuan Gao, Yanqing Zhu, Yong Tan. Exercise-induced Nitric Oxide Contributes to Spatial Memory and Hippocampal Capillaries in Rats. International journal of sports medicine. vol 41. issue 13. 2021-01-07. PMID:32643775. |
four weeks of running exercise significantly improved spatial memory ability and increased the number of capillaries in the cornu ammonis 1 subfield and dentate gyrus of sprague-dawley rats. |
2021-01-07 |
2023-08-13 |
rat |
| Yingqiang Qi, Sanrong Wang, Yanmin Luo, Wei Huang, Linmu Chen, Yi Zhang, Xin Liang, Jing Tang, Yang Zhang, Lei Zhang, Fenglei Chao, Yuan Gao, Yanqing Zhu, Yong Tan. Exercise-induced Nitric Oxide Contributes to Spatial Memory and Hippocampal Capillaries in Rats. International journal of sports medicine. vol 41. issue 13. 2021-01-07. PMID:32643775. |
therefore, during running excise, endogenous nitric oxide may contribute to regulating spatial memory ability and angiogenesis in cornu ammonis 1 subfield and dentate gyrus of the hippocampus. |
2021-01-07 |
2023-08-13 |
rat |
| Heechul Jun, Allen Bramian, Shogo Soma, Takashi Saito, Takaomi C Saido, Kei M Igarash. Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease. Neuron. vol 107. issue 6. 2020-11-20. PMID:32697942. |
mild disruption of mec grid cells emerged in younger app-ki mice, although the spatial memory and ca1 remapping of the animals remained intact. |
2020-11-20 |
2023-08-13 |
mouse |
| Garrett Smith, Asha Rani, Ashok Kumar, Jolie Barter, Thomas C Foste. Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 25. 2020-10-26. PMID:32376783. |
few genes correlated with spatial memory across age groups, with a greater number in region ca1. |
2020-10-26 |
2023-08-13 |
rat |
| Garrett Smith, Asha Rani, Ashok Kumar, Jolie Barter, Thomas C Foste. Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 25. 2020-10-26. PMID:32376783. |
age-related ca1 degs, correlated with spatial memory, were linked to regulation of neural activity. |
2020-10-26 |
2023-08-13 |
rat |
| Malihe Sadeghi, Parham Reisi, Maryam Radahmad. The effects of CCK-8S on spatial memory and long-term potentiation at CA1 during induction of stress in rats. Iranian journal of basic medical sciences. vol 20. issue 12. 2020-10-01. PMID:29238473. |
the effects of cck-8s on spatial memory and long-term potentiation at ca1 during induction of stress in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Malihe Sadeghi, Parham Reisi, Maryam Radahmad. The effects of CCK-8S on spatial memory and long-term potentiation at CA1 during induction of stress in rats. Iranian journal of basic medical sciences. vol 20. issue 12. 2020-10-01. PMID:29238473. |
we aimed to evaluate the effects of systemic administration of cck exactly before induction of stress on spatial memory and synaptic plasticity at ca1 in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Zhu-Jin Song, San-Juan Yang, Lan Han, Bin Wang, Guoqi Zh. Postnatal calpeptin treatment causes hippocampal neurodevelopmental defects in neonatal rats. Neural regeneration research. vol 14. issue 5. 2020-10-01. PMID:30688269. |
calpeptin administration impaired spatial memory, caused anxiety-like behavior in adulthood, reduced the number and area of apical dendritic spines, and decreased actin polymerization in the hippocampus, but did not affect the number of neun-positive cells in the hippocampal ca1 region. |
2020-10-01 |
2023-08-13 |
rat |
| Alfonso Diaz, Samuel Treviño, Guadalupe Pulido-Fernandez, Estefanía Martínez-Muñoz, Nallely Cervantes, Blanca Espinosa, Karla Rojas, Francisca Pérez-Severiano, Sergio Montes, Moises Rubio-Osornio, Guevara Jorg. Epicatechin Reduces Spatial Memory Deficit Caused by Amyloid-β25⁻35 Toxicity Modifying the Heat Shock Proteins in the CA1 Region in the Hippocampus of Rats. Antioxidants (Basel, Switzerland). vol 8. issue 5. 2020-09-30. PMID:31052185. |
epicatechin reduces spatial memory deficit caused by amyloid-β25⁻35 toxicity modifying the heat shock proteins in the ca1 region in the hippocampus of rats. |
2020-09-30 |
2023-08-13 |
rat |