| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christine Mikhail, Khaled Elgaaly, Ahmed Abd El Latif Abd El Hamid, Olfat Shaker, Shereen Al. Gustatory Dysfunction among a Sample of Depressed Egyptian Adults under Antidepressants Therapy: A Retrospective Cohort Study. International journal of dentistry. vol 2021. 2021-03-23. PMID:33747081. |
these patients were distributed into three equal groups (tricyclic antidepressants (tca), selective serotonin reuptake inhibitors (ssris), and psychotherapy) and were assessed for gustatory detection and recognition thresholds using the filter paper disc method through a scoring system. |
2021-03-23 |
2023-08-13 |
human |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
serotonin or 5-hydroxytryptamine (5-ht) is an important neurotransmitter that is found in mammalian taste buds and can regulate the output of intragemmal signaling networks onto afferent nerve fibers. |
2020-09-30 |
2023-08-13 |
mouse |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
however, it is unclear how 5-ht is produced, synthesized locally inside taste buds or absorbed from outside sources. |
2020-09-30 |
2023-08-13 |
mouse |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
in this study, we attempt to address this question by delineating the process of possible 5-ht biosynthesis within taste buds. |
2020-09-30 |
2023-08-13 |
mouse |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
and abolishment of tph2 did not affect the production of intragemmal 5-ht or alter tbcs; the mutant mice did not show any changes in behavioral responses to all five primary taste qualities: sweet, umami, bitter, salty, and sour. |
2020-09-30 |
2023-08-13 |
mouse |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
then we identified that 5-htp as well as aadc are abundant in type iii tbcs; and application of an aadc inhibitor significantly blocked the production of 5-ht in taste buds. |
2020-09-30 |
2023-08-13 |
mouse |
| Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huan. Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30534058. |
in contrast, administration of an inhibitor on serotonin-reuptake transporters had minimal impact on the 5-ht amount in taste buds, indicating that exogenous 5-ht is not a major source for the intragemmal transmitter. |
2020-09-30 |
2023-08-13 |
mouse |
| I. Lucki, J.M. Marcocci. Discriminated taste aversion with a 5-HT(1A) agonist measured using saccharin preference. Behavioural pharmacology. vol 2. issue 4 And 5. 2019-11-20. PMID:11224077. |
discriminated taste aversion with a 5-ht(1a) agonist measured using saccharin preference. |
2019-11-20 |
2023-08-12 |
rat |
| Tatsufumi Nakamura, Naoki Matsuyama, Masato Kirino, Masanori Kasai, Sadao Kiyohara, Takanori Ikenag. Distribution, Innervation, and Cellular Organization of Taste Buds in the Sea Catfish, Plotosus japonicus. Brain, behavior and evolution. vol 89. issue 3. 2018-03-05. PMID:28502972. |
serotonin immunohistochemistry demonstrated that most of the taste buds in all the organs examined contained disk-shaped serotonin-immunopositive cells in their basal region. |
2018-03-05 |
2023-08-13 |
Not clear |
| J M Stratford, E D Larson, R Yang, E Salcedo, T E Finge. 5-HT The Journal of comparative neurology. vol 525. issue 10. 2018-03-02. PMID:28316078. |
5-ht taste buds contain multiple cell types with each type expressing receptors and transduction components for a subset of taste qualities. |
2018-03-02 |
2023-08-13 |
Not clear |
| Ivo Vlaev, Molly J Crockett, Luke Clark, Ulrich Müller, Trevor W Robbin. Serotonin enhances the impact of health information on food choice. Cognitive, affective & behavioral neuroscience. vol 17. issue 3. 2018-02-06. PMID:28116581. |
we investigated the effects of an acute dose of the serotonin reuptake inhibitor citalopram on choices between food items that differed along taste and health attributes, compared with placebo and the noradrenaline reuptake inhibitor atomoxetine. |
2018-02-06 |
2023-08-13 |
human |
| Aurelie Vandenbeuch, Sue C Kinnamo. Glutamate: Tastant and Neuromodulator in Taste Buds. Advances in nutrition (Bethesda, Md.). vol 7. issue 4. 2018-01-18. PMID:27422519. |
evidence suggests that glutamate has an efferent function on taste cells and modulates the release of other neurotransmitters such as serotonin and atp. |
2018-01-18 |
2023-08-13 |
Not clear |
| Courtney E Wilson, Thomas E Finger, Sue C Kinnamo. Type III Cells in Anterior Taste Fields Are More Immunohistochemically Diverse Than Those of Posterior Taste Fields in Mice. Chemical senses. vol 42. issue 9. 2017-11-29. PMID:28968659. |
here, we compare type iii cells in four taste fields: fungiform, soft palate, circumvallate, and foliate in terms of reactivity to four canonical markers of type iii cells: polycystic kidney disease 2-like 1 (pkd2l1), synaptosomal associated protein 25 (snap25), serotonin (5-ht), and glutamate decarboxylase 67 (gad67). |
2017-11-29 |
2023-08-13 |
mouse |
| Courtney E Wilson, Thomas E Finger, Sue C Kinnamo. Type III Cells in Anterior Taste Fields Are More Immunohistochemically Diverse Than Those of Posterior Taste Fields in Mice. Chemical senses. vol 42. issue 9. 2017-11-29. PMID:28968659. |
our findings indicate that while pkd2l1, 5-ht, and snap25 are highly coincident in posterior taste fields, they diverge in anterior taste fields. |
2017-11-29 |
2023-08-13 |
mouse |
| Eric D Larson, Aurelie Vandenbeuch, Anja Voigt, Wolfgang Meyerhof, Sue C Kinnamon, Thomas E Finge. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631478. |
activation of taste buds triggers the release of several neurotransmitters, including atp and serotonin (5-hydroxytryptamine; 5-ht). |
2016-03-28 |
2023-08-13 |
mouse |
| Eric D Larson, Aurelie Vandenbeuch, Anja Voigt, Wolfgang Meyerhof, Sue C Kinnamon, Thomas E Finge. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631478. |
type iii taste cells release 5-ht directly in response to acidic (sour) stimuli and indirectly in response to bitter and sweet tasting stimuli. |
2016-03-28 |
2023-08-13 |
mouse |
| Eric D Larson, Aurelie Vandenbeuch, Anja Voigt, Wolfgang Meyerhof, Sue C Kinnamon, Thomas E Finge. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631478. |
although atp is necessary for activation of nerve fibers for all taste stimuli, the role of 5-ht is unclear. |
2016-03-28 |
2023-08-13 |
mouse |
| Eric D Larson, Aurelie Vandenbeuch, Anja Voigt, Wolfgang Meyerhof, Sue C Kinnamon, Thomas E Finge. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631478. |
in mice expressing gfp under the control of the 5-ht(3a) promoter, a subset of cells in the geniculate ganglion and nerve fibers in taste buds are gfp-positive. |
2016-03-28 |
2023-08-13 |
mouse |
| Eric D Larson, Aurelie Vandenbeuch, Anja Voigt, Wolfgang Meyerhof, Sue C Kinnamon, Thomas E Finge. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631478. |
our results suggest that 5-ht released from type iii cells activates gustatory nerve fibers via 5-ht3 receptors, accounting for a significant proportion of the neural taste response. |
2016-03-28 |
2023-08-13 |
mouse |
| Susan P Travers, Marion E Fran. Taste bud leptin: sweet dampened at initiation site. Chemical senses. vol 40. issue 4. 2016-01-29. PMID:25740303. |
in this issue of chemical senses, a careful study by glendinning and colleagues, find no effects of leptin on sweet-evoked chorda tympani responses, whereas an equally careful study by meredith and colleagues, find decreased release of atp and increased release of 5-ht from taste buds in response to sweet stimuli. |
2016-01-29 |
2023-08-13 |
mouse |