| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T B Nucci, L G S Branco, L H Gargaglion. 5-HT1A, but not 5-HT2 and 5-HT7, receptors in the nucleus raphe magnus modulate hypoxia-induced hyperpnoea. Acta physiologica (Oxford, England). vol 193. issue 4. 2008-08-20. PMID:18363900. |
5-ht1a, but not 5-ht2 and 5-ht7, receptors in the nucleus raphe magnus modulate hypoxia-induced hyperpnoea. |
2008-08-20 |
2023-08-12 |
Not clear |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
the acth response to 5-ht is mediated via 5-ht1a, 5-ht1b, 5-ht2a and 5-ht2c receptors and an involvement of the 5-ht4, 5-ht5 and 5-ht7 receptors is proposed. |
2008-02-14 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
peripheral secretion of avp upon stimulation with 5-ht is mediated via 5-ht2c, 5-ht4 and 5-ht7 receptors but not 5-ht1a receptors. |
2008-02-14 |
2023-08-12 |
rat |
| Takeo Ishiyama, Kumiko Tokuda, Tadashi Ishibashi, Akira Ito, Satoko Toma, Yukihiro Ohn. Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17662268. |
lurasidone (sm-13496) is a novel atypical antipsychotic with high affinities to dopamine d2, serotonin 5-ht7, 5-ht2a, 5-ht1a receptors and alpha2c adrenoceptor. |
2008-01-14 |
2023-08-12 |
rat |
| A Dogrul, M Seyre. Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord. British journal of pharmacology. vol 149. issue 5. 2007-02-02. PMID:16921395. |
systemic morphine produce antinociception mediated by spinal 5-ht7, but not 5-ht1a and 5-ht2 receptors in the spinal cord. |
2007-02-02 |
2023-08-12 |
Not clear |
| Hitoshi Kita, Satomi Chiken, Yoshihisa Tachibana, Atsushi Namb. Serotonin modulates pallidal neuronal activity in the awake monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 1. 2007-01-29. PMID:17202474. |
previous anatomical studies and in vitro physiological studies in other brain areas have suggested the following possibilities: (1) 5-ht suppresses gabaergic inhibition through presynaptic 5-ht1b receptors; (2) 5-ht decreases the firing of pallidal neurons through postsynaptic 5-ht1a receptors; and (3) 5-ht postsynaptically excites pallidal neurons through activation of 5-ht2c, 5-ht4, or 5-ht7 receptors. |
2007-01-29 |
2023-08-12 |
monkey |
| Luciane H Gargaglioni, Kênia C Bícego, Tatiane B Nucci, Luiz G S Branc. Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory response. Respiratory physiology & neurobiology. vol 153. issue 1. 2006-09-29. PMID:16310416. |
to this end, pulmonary ventilation (v(e)) of rats was measured before and after intra-avpo microinjection of methysergide (a 5-ht1 and 5-ht2 receptor antagonist), way-100635 (a 5-ht1a receptor antagonist) and sb-269970 (a 5-ht7 receptor antagonist), followed by 60 min of hypoxia exposure (7% o2). |
2006-09-29 |
2023-08-12 |
rat |
| Luciane H Gargaglioni, Kênia C Bícego, Tatiane B Nucci, Luiz G S Branc. Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory response. Respiratory physiology & neurobiology. vol 153. issue 1. 2006-09-29. PMID:16310416. |
therefore, the current data provide the evidence that 5-ht acting on 5-ht1a and 5-ht7 receptors in the avpo exert an inhibitory modulation on the hvr. |
2006-09-29 |
2023-08-12 |
rat |
| Georgina Pérez-García, Claudia Gonzalez-Espinosa, Alfredo Menese. An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during memory consolidation. Behavioural brain research. vol 169. issue 1. 2006-04-18. PMID:16480781. |
actually, pharmacological naïve untrained and autoshaping-trained rats showed significant differences, the latter groups expressing, in decreasing order, 5-ht1a < 5-ht6 < 5-ht4 < or = 5-ht7 receptors mrna in prefrontal cortex and hippocampus. |
2006-04-18 |
2023-08-12 |
rat |
| Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. |
neurophysiological studies have shown that serotonergic ligands that bind to 5-ht1a, 5-ht7, and 5-ht4 serotonin receptors in brain stem have beneficial effects on respiratory neurons during opioid-induced respiratory depression. |
2006-02-23 |
2023-08-12 |
Not clear |
| Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. |
we therefore examined the effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), an agonist of 5-ht1a and 5-ht7 receptors, and zacopride, an agonist of 5-ht4 receptors, to establish whether these ligands would reverse opioid-induced respiratory depression and hypoxia without affecting the immobilizing properties of the opioid drug etorphine. |
2006-02-23 |
2023-08-12 |
Not clear |
| Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. |
we conclude that serotonergic drugs that act on 5-ht1a, 5-ht7, and 5-ht4 receptors reverse opioid-induced respiratory depression and hypoxia without reversing catatonic immobilization. |
2006-02-23 |
2023-08-12 |
Not clear |
| Suzana Uzun, Oliver Kozumplik, Ninoslav Mimica, Vera Folnegović-Smal. Aripiprazole: an overview of a novel antipsychotic. Psychiatria Danubina. vol 17. issue 1-2. 2006-02-15. PMID:16395846. |
aripiprazole exhibits high affinity for dopamine d2 and d3, serotonin 5-ht1a and 5-ht2a receptors, moderate affinity for dopamine d4, serotonin 5-ht2c and 5-ht7, alpha1-adrenergic and histamine h1 receptors. |
2006-02-15 |
2023-08-12 |
Not clear |
| Daniel O Kellett, S Clare Stanford, Benedito H Machado, David Jordan, Andrew G Ramag. Effect of 5-HT depletion on cardiovascular vagal reflex sensitivity in awake and anesthetized rats. Brain research. vol 1054. issue 1. 2005-11-14. PMID:16054601. |
antagonism of central 5-ht1a and 5-ht7 receptors inhibits reflex-evoked vagal bradycardias indicating that 5-ht is released during these reflexes. |
2005-11-14 |
2023-08-12 |
rat |
| Andrzej J Bojarski, Maria H Paluchowska, Beata Duszyńska, Aleksandra Kłodzińska, Ewa Tatarczyńska, Ewa Chojnacka-Wójci. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics. Bioorganic & medicinal chemistry. vol 13. issue 6. 2005-08-02. PMID:15727878. |
1-aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-ht1a, 5-ht2a, 5-ht7), alpha1-adrenergic, and dopaminergic d2 receptors, and in vivo 5-ht1a functional characteristics. |
2005-08-02 |
2023-08-12 |
mouse |
| Steven E Harte, Robert G Kender, George S Borszc. Activation of 5-HT1A and 5-HT7 receptors in the parafascicular nucleus suppresses the affective reaction of rats to noxious stimulation. Pain. vol 113. issue 3. 2005-05-09. PMID:15661450. |
activation of 5-ht1a and 5-ht7 receptors in the parafascicular nucleus suppresses the affective reaction of rats to noxious stimulation. |
2005-05-09 |
2023-08-12 |
rat |
| Steven E Harte, Robert G Kender, George S Borszc. Activation of 5-HT1A and 5-HT7 receptors in the parafascicular nucleus suppresses the affective reaction of rats to noxious stimulation. Pain. vol 113. issue 3. 2005-05-09. PMID:15661450. |
intra-npf administration of the 5-ht1a receptor antagonist way-100635 (0.05 or 0.5 microg/side), or the 5-ht7 receptor antagonist sb-269970 (1 or 2 microg/side), but not the dopamine d2 receptor antagonist raclopride (10 microg/side), reversed 8-oh-dpat induced elevations in vocalization thresholds. |
2005-05-09 |
2023-08-12 |
rat |
| Geoffrey Andrew Lambert, Cathy Donaldson, Karen Lisa Hoskin, Peter Michael Boers, Alessandro Stefano Zagam. Dilatation induced by 5-HT in the middle meningeal artery of the anaesthetised cat. Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 6. 2005-02-22. PMID:15197536. |
dose-response curves of vascular resistance changes to intravenous injection of 5-ht were not significantly affected by way100635 (5-ht1a antagonist), gr127935 (5-ht(1b/1d) antagonist), methiothepin (5-ht2c and 5-ht7 antagonist), ketanserin (5-ht2a antagonist), sb203186 (5-ht4 antagonist) or cervical sympathectomy, but were blocked by the 5-ht(3/4) antagonist tropisetron, the 5-ht3 antagonist ondansetron, the ganglion-blocking drug hexamethonium and by vagotomy. |
2005-02-22 |
2023-08-12 |
cat |
| Araceli Sánchez-Lopez, David Centurión, Erika Vázquez, Udayasankar Arulmani, Pramod R Saxena, Carlos M Villaló. Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors. British journal of pharmacology. vol 140. issue 4. 2004-11-09. PMID:14504136. |
treatment with saline or the antagonists gr 127935 (5-ht1b/1d), the combination of way 100635 (5-ht1a) plus gr 127935, ritanserin (5-ht2), tropisetron (5-ht3/4), ly215840 (5-ht7) or a cocktail of antagonists/inhibitors consisting of yohimbine (alpha2), prazosin (alpha1), ritanserin, gr 127935, way 100635 and indomethacin (cyclooxygenase), but was abolished by methiothepin (5-ht1/2/6/7 and recombinant 5-ht5a/5b). |
2004-11-09 |
2023-08-12 |
rat |
| Laszlo G Harsing, Ibolya Prauda, Jozsef Barkoczy, Peter Matyus, Zsolt Jurany. A 5-HT7 heteroreceptor-mediated inhibition of [3H]serotonin release in raphe nuclei slices of the rat: evidence for a serotonergic-glutamatergic interaction. Neurochemical research. vol 29. issue 8. 2004-08-19. PMID:15260125. |
these findings indicate that 5-ct inhibits [3h]5-ht overflow from raphe nuclei slices of the rat by stimulation of 5-ht7 and 5-ht(1b/1d receptors, whereas the role of 5-ht1a receptors in this inhibition is less pronounced. |
2004-08-19 |
2023-08-12 |
rat |