| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Charles E Glatt, Maricel Tampilic, Carroll Christie, Joe DeYoung, Nelson B Freime. Re-screening serotonin receptors for genetic variants identifies population and molecular genetic complexity. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 124B. issue 1. 2004-07-28. PMID:14681923. |
we have re-screened the genes for the 5-ht1a, 5-ht2a, 5-ht2c, and 5-ht7 serotonin receptors for genetic variants in a large african-american and caucasian-american population sample. |
2004-07-28 |
2023-08-12 |
human |
| Marton Graf, Rita Jakus, Sandor Kantor, Gyorgy Levay, Gyorgy Bagd. Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy. Neuroscience letters. vol 359. issue 1-2. 2004-05-21. PMID:15050708. |
selective 5-ht1a and 5-ht7 antagonists decrease epileptic activity in the wag/rij rat model of absence epilepsy. |
2004-05-21 |
2023-08-12 |
rat |
| Marton Graf, Rita Jakus, Sandor Kantor, Gyorgy Levay, Gyorgy Bagd. Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy. Neuroscience letters. vol 359. issue 1-2. 2004-05-21. PMID:15050708. |
recent studies have provided evidence that activation of 5-ht1a receptors increases epileptic activity in the wag/rij rat model of absence epilepsy, and additional data have suggested the involvement of 5-ht7 receptors as well. |
2004-05-21 |
2023-08-12 |
rat |
| Marton Graf, Rita Jakus, Sandor Kantor, Gyorgy Levay, Gyorgy Bagd. Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy. Neuroscience letters. vol 359. issue 1-2. 2004-05-21. PMID:15050708. |
these results provide evidence that activation of 5-ht1a and 5-ht7 receptors plays a significant role in regulating swd activity in this animal model of absence epilepsy. |
2004-05-21 |
2023-08-12 |
rat |
| Jeffrey Sprouse, Linda Reynolds, Xingfang Li, John Braselton, Anne Schmid. 8-OH-DPAT as a 5-HT7 agonist: phase shifts of the circadian biological clock through increases in cAMP production. Neuropharmacology. vol 46. issue 1. 2004-04-05. PMID:14654097. |
by itself, 8-oh-dpat produced a concentration-dependent phase advance that was sensitive to co-application with 5-ht7 antagonists (ritanserin, mesulergine, sb-269970), but not to 5-ht1a antagonists (way-100,635, uh-301). |
2004-04-05 |
2023-08-12 |
rat |
| L Manuel-Apolinar, A Menese. 8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production. Behavioural brain research. vol 148. issue 1-2. 2004-03-01. PMID:14684258. |
animals were submitted to an associative learning task named pavlovian/instrumental autoshaping (p/i-a) and treated with selective 5-ht1a and 5-ht7 receptor agonists and antagonists. |
2004-03-01 |
2023-08-12 |
Not clear |
| Miki Kishitake, Korehito Yamanouch. Effects of highly or relatively selective 5-HT1A receptor agonists on lordosis in female rats. Zoological science. vol 20. issue 9. 2004-01-05. PMID:14578574. |
the injected agents were the selective 5-ht1a receptor agonist, buspirone (bus), the highly selective 5-ht1a receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin ((+/-)8-oh-dpat), and the 5-ht1a and 5-ht7 receptor agonist, (r)-8-hydroxy-2-(di-n-propylamino)tetralin ((+)8-oh-dpat). |
2004-01-05 |
2023-08-12 |
rat |
| H Elliott Albers, Mary Karom, Debra Smit. Serotonin and vasopressin interact in the hypothalamus to control communicative behavior. Neuroreport. vol 13. issue 7. 2002-07-16. PMID:12004193. |
in addition, the finding that 8-oh-dpat, cgs-12066a and sc53116 also inhibited avp-induced flank marking suggests that 5-ht could also inhibit flank marking by acting through 5-ht1a, 5-ht7, 5-ht1b and/or 5-ht4 receptor subtypes. |
2002-07-16 |
2023-08-12 |
Not clear |
| Catherine H Gill, Ellen M Soffin, Jim J Hagan, Ceri H Davie. 5-HT7 receptors modulate synchronized network activity in rat hippocampus. Neuropharmacology. vol 42. issue 1. 2002-02-20. PMID:11750918. |
the selective 5-ht1a receptor antagonist n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexane carboxamide (way 100635) reversed the depression of bursting activity whereas the 5-ht7 receptor antagonist, (r)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (sb-269970; 1-10 microm), but not the 5-ht1a, 4 or 6 receptor antagonists way100635 (10 microm), sb-204070 (10 microm) and sb-271046 (10 microm), reversed the increase in bursting activity. |
2002-02-20 |
2023-08-12 |
rat |
| S M Biello, R I Dafter. MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro. Brain research. vol 920. issue 1-2. 2002-02-07. PMID:11716826. |
in the present study, we tested the ability of mdma and fenfluramine treatment to alter the ability of the circadian clock to reset in response to an agonist of the 5-ht1a and 5-ht7 receptor subtypes soon after treatment with the drugs, and then again at 20 weeks. |
2002-02-07 |
2023-08-12 |
human |
| M Masellis, V S Basile, H Y Meltzer, J A Lieberman, S Sevy, D A Goldman, M W Hamblin, F M Macciardi, J L Kenned. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia research. vol 47. issue 1. 2001-04-26. PMID:11163544. |
the affinity of clozapine for 5-ht2a, 5-ht2c, 5-ht6, 5-ht7, and 5-ht1a receptors has been suggested to contribute to various aspects of its complex clinical actions. |
2001-04-26 |
2023-08-12 |
Not clear |
| M Masellis, V S Basile, H Y Meltzer, J A Lieberman, S Sevy, D A Goldman, M W Hamblin, F M Macciardi, J L Kenned. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia research. vol 47. issue 1. 2001-04-26. PMID:11163544. |
this study examined the hypothesis that genetic variation in 5-ht1a, 5-ht6, and 5-ht7 receptor genes is involved in the variability observed in response to clozapine. |
2001-04-26 |
2023-08-12 |
Not clear |
| A Menese. 5-HT system and cognition. Neuroscience and biobehavioral reviews. vol 23. issue 8. 2000-02-11. PMID:10643820. |
in this regard, it is probable that selective drugs with agonists, neutral antagonist, agonists or inverse agonist properties for 5-ht1a, 5-ht(1b/1d), 5-ht(2a/2b/2c), 5-ht4 and 5-ht7 receptors could constitute a new therapeutic opportunity for learning and memory alterations. |
2000-02-11 |
2023-08-12 |
Not clear |
| P W Burnet, T Sharp, S M LeCorre, P J Harriso. Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock. Neuroscience letters. vol 277. issue 2. 2000-02-08. PMID:10624814. |
we have measured the mrnas encoding 5-ht1a, 5-ht2a, 5-ht2c and 5-ht7 receptors, and the 5-ht transporter, in rat brain after single ecs, repeated ecs, and 3 weeks after repeated ecs. |
2000-02-08 |
2023-08-12 |
rat |
| M P Arolfo, B A McMille. Effects of amperozide and tiospirone, atypical antipsychotic 5-HT2 drugs, on food-reinforced behavior in rats. Physiology & behavior. vol 68. issue 1-2. 2000-01-31. PMID:10627067. |
tiospirone (tsp) is a 5-ht2 receptor antagonist with affinity for d2, 5-ht1a, and 5-ht7, and sigma receptors, which can decrease consumption of ethanol while increasing food intake. |
2000-01-31 |
2023-08-12 |
rat |
| P B Hedlund, M J Carson, J G Sutcliffe, E A Thoma. Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. Biochemical pharmacology. vol 58. issue 11. 1999-12-17. PMID:10571256. |
oleamide belongs to a family of amidated lipids with diverse biological activities, including sleep induction and signaling modulation of several 5-hydroxytryptamine (5-ht) receptor subtypes, including 5-ht1a, 5-ht2a/2c, and 5-ht7. |
1999-12-17 |
2023-08-12 |
Not clear |
| D R Thomas, D N Middlemiss, S G Taylor, P Nelson, A M Brow. 5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors. British journal of pharmacology. vol 128. issue 1. 1999-11-22. PMID:10498847. |
5-ct stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-ht7 and 5-ht1a receptors. |
1999-11-22 |
2023-08-12 |
human |
| R Markstein, M Matsumoto, C Kohler, H Togashi, M Yoshioka, D Hoye. Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 359. issue 6. 1999-10-04. PMID:10431755. |
cyclic amp accumulation induced by 1 microm 5-ht was partly inhibited by the selective 5-ht1a receptor antagonist way 100,635 (1 microm), the selective 5-ht4 receptor antagonist sb 203,186 (1 microm), and the 5-ht2a/c/ 5-ht7 receptor antagonist mesulergine (25 microm). |
1999-10-04 |
2023-08-12 |
rat |
| R Markstein, M Matsumoto, C Kohler, H Togashi, M Yoshioka, D Hoye. Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 359. issue 6. 1999-10-04. PMID:10431755. |
5-ht1a, 5-ht7 and 5-ht4 receptors, are involved in mediating 5-ht-induced cyclic amp formation in rat hippocampus. |
1999-10-04 |
2023-08-12 |
rat |
| J L Yau, T Olsson, J Noble, J R Seck. Serotonin receptor subtype gene expression in the hippocampus of aged rats following chronic amitriptyline treatment. Brain research. Molecular brain research. vol 70. issue 2. 1999-09-08. PMID:10407176. |
administration for 10 weeks altered 5-ht1a, 5-ht2a, 5-ht2c or 5-ht7 receptor mrna expression in any hippocampal subregion. |
1999-09-08 |
2023-08-12 |
rat |