| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Stefański, W Pałejko, A Bidziński, W Kostowski, A Płaźni. Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A receptor agonists. Neuropharmacology. vol 32. issue 10. 1994-02-25. PMID:7905194. |
an involvement of serotonergic innervation of the hippocampus (hp) and the nucleus accumbens septi (nas) in anxiolytic activity of benzodiazepine midazolam and 5-ht1a receptor agonists was studied in two different animal models of anxiety. |
1994-02-25 |
2023-08-12 |
Not clear |
| R Stefański, W Pałejko, A Bidziński, W Kostowski, A Płaźni. Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A receptor agonists. Neuropharmacology. vol 32. issue 10. 1994-02-25. PMID:7905194. |
serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-ht1a receptor agonists. |
1994-02-25 |
2023-08-12 |
Not clear |
| W J McBride, J M Murphy, G J Gatto, A D Levy, L Lumeng, T K L. Serotonin and dopamine systems regulating alcohol intake. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 1. 1993-10-07. PMID:1726986. |
neurochemical data indicate that high alcohol seeking behavior (when compared with data from rats with low alcohol seeking characteristics) is associated with (a) lower contents of 5-ht in certain limbic regions, e.g., n. accumbens (acb), frontal cortex, (b) a lower content of da in the acb, and (c) higher densities of 5-ht1a receptors in certain limbic regions, e.g., cerebral cortex. |
1993-10-07 |
2023-08-11 |
rat |
| K Yoshimoto, W J McBrid. Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1356241. |
the data indicate that (a) the 5-ht neurons projecting to the nucleus accumbens from the dorsal raphe nucleus can be activated by excitatory amino acid receptors and inhibited by stimulation of 5-ht1a autoreceptors, and (b) the dorsal raphe nucleus 5-ht neuronal system may regulate the ventral tegmental area da projection to the nucleus accumbens. |
1992-10-22 |
2023-08-11 |
rat |
| K Yoshimoto, W J McBrid. Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1356241. |
the effects of microinfusing l-glutamate, serotonin (5-ht), (+-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-oh dpat; a 5-ht1a agonist), and muscimol (a gabaa agonist) into the dorsal raphe nucleus on the extracellular levels of 5-ht, dopamine (da) and their metabolites in the nucleus accumbens were studied in unanesthetized, freely moving, adult male wistar rats, using the technique of microdialysis coupled with small-bore hplc. |
1992-10-22 |
2023-08-11 |
rat |
| A Fernández-Guasti, A L Escalante, S Ahlenius, V Hillegaart, K Larsso. Stimulation of 5-HT1A and 5-HT1B receptors in brain regions and its effects on male rat sexual behaviour. European journal of pharmacology. vol 210. issue 2. 1992-07-10. PMID:1534765. |
in the present series of experiments we compared the effect of injecting serotonin (40 micrograms/cannula), the 5-ht1a agonist, 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) (5.0 micrograms/cannula), and the 5-ht1b/c agonist, trifluoromethyl-phenyl-piperazine (tfmpp) (1.0 micrograms/cannula), into the preoptic area, the nucleus accumbens and the nucleus raphe dorsalis. |
1992-07-10 |
2023-08-11 |
rat |
| S Hjorth, T Shar. Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. Life sciences. vol 48. issue 18. 1991-05-30. PMID:1826937. |
to further study the putative differences in regulation between ascending 5-ht projections from the raphe nuclei we have used microdialysis to measure the release of 5-ht in ventral hippocampus, globus pallidus, dorsal hippocampus, frontal cortex, nucleus accumbens and medial septum, following systemic administration of the specific 5-ht1a agonist 8-oh-dpat. |
1991-05-30 |
2023-08-11 |
rat |
| W J McBride, J M Murphy, L Lumeng, T K L. Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats. Alcohol (Fayetteville, N.Y.). vol 7. issue 3. 1990-06-05. PMID:2184832. |
neurochemical data indicate that high alcohol-seeking behavior (when compared with data from rats with low alcohol-seeking characteristics) is associated with: a) lower (10-20%; p less than 0.05) contents of 5-ht in certain limbic regions (e.g., nucleus accumbens, frontal cortex, hypothalamus and hippocampus); b) a lower (10-15%; p less than 0.05) content of da in the nucleus accumbens; c) higher (20-35%; p less than 0.05) densities of 5-ht1a binding sites in some limbic regions (e.g., medial nucleus accumbens, medial prefrontal cortex and ventral hippocampus); and d) a greater (20-50%) density of gaba axon terminals in the nucleus accumbens. |
1990-06-05 |
2023-08-11 |
rat |
| S Ahlenius, V Hillegaart, A Wijkströ. Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 339. issue 5. 1989-09-29. PMID:2570361. |
this increase in dopa accumulation was antagonized dose-dependently in the nucleus accumbens and ventro-medial neostriatum, but not in the other two regions, by treatment with the 5-ht1a receptor agonist 8-oh-dpat, 0.15-2.4 mumol kg-1, whereas the partial dopamine d2 receptor agonist (-)3-ppp, 2.5-10.0 mumol kg-1, or the full dopamine d2 receptor agonist quinpirole, 0.05-0.8 mumol kg-1, antagonized the reserpine-induced increase in dopa accumulation uniformly in all four regions of the striatum. |
1989-09-29 |
2023-08-11 |
rat |