| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eunice Y Yuen, Qian Jiang, Paul Chen, Zhenglin Gu, Jian Feng, Zhen Ya. Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 23. 2006-02-17. PMID:15944377. |
serotonin 5-ht1a receptors regulate nmda receptor channels through a microtubule-dependent mechanism. |
2006-02-17 |
2023-08-12 |
Not clear |
| Mateusz Nowak, Marcin Kołaczkowski, Maciej Pawłowski, Andrzej J Bojarsk. Homology modeling of the serotonin 5-HT1A receptor using automated docking of bioactive compounds with defined geometry. Journal of medicinal chemistry. vol 49. issue 1. 2006-02-16. PMID:16392805. |
homology modeling of the serotonin 5-ht1a receptor using automated docking of bioactive compounds with defined geometry. |
2006-02-16 |
2023-08-12 |
Not clear |
| Suzana Uzun, Oliver Kozumplik, Ninoslav Mimica, Vera Folnegović-Smal. Aripiprazole: an overview of a novel antipsychotic. Psychiatria Danubina. vol 17. issue 1-2. 2006-02-15. PMID:16395846. |
aripiprazole exhibits high affinity for dopamine d2 and d3, serotonin 5-ht1a and 5-ht2a receptors, moderate affinity for dopamine d4, serotonin 5-ht2c and 5-ht7, alpha1-adrenergic and histamine h1 receptors. |
2006-02-15 |
2023-08-12 |
Not clear |
| Stefan Geyer, Giuseppe Luppino, Hendrik Ekamp, Karl Zille. The macaque inferior parietal lobule: cytoarchitecture and distribution pattern of serotonin 5-HT1A binding sites. Anatomy and embryology. vol 210. issue 5-6. 2006-02-10. PMID:16180022. |
the macaque inferior parietal lobule: cytoarchitecture and distribution pattern of serotonin 5-ht1a binding sites. |
2006-02-10 |
2023-08-12 |
monkey |
| Stefan Geyer, Giuseppe Luppino, Hendrik Ekamp, Karl Zille. The macaque inferior parietal lobule: cytoarchitecture and distribution pattern of serotonin 5-HT1A binding sites. Anatomy and embryology. vol 210. issue 5-6. 2006-02-10. PMID:16180022. |
in order to obtain a more valid anatomical map of the ipl, we studied the distribution pattern of serotonin 5-ht1a binding sites (i.e., the domain of synaptic transmission and cortical information processing) and cytoarchitecture with an observer-independent technique (thus avoiding the subjectivity inherent in visually guided microstructural parcellations). |
2006-02-10 |
2023-08-12 |
monkey |
| Mary Druse, Nuzhath F Tajuddin, Roberta A Gillespie, Phong L. Signaling pathways involved with serotonin1A agonist-mediated neuroprotection against ethanol-induced apoptosis of fetal rhombencephalic neurons. Brain research. Developmental brain research. vol 159. issue 1. 2006-02-03. PMID:16081165. |
we also found that 5-ht1a agonists diminished the ethanol-associated reduction of 5-ht neurons and other fetal rhombencephalic neurons by attenuating the pro-apoptotic effects of ethanol. |
2006-02-03 |
2023-08-12 |
Not clear |
| R B D'Eath, E Ormandy, A B Lawrence, B E H Sumner, S L Meddl. Resident-intruder trait aggression is associated with differences in lysine vasopressin and serotonin receptor 1A (5-HT1A) mRNA expression in the brain of pre-pubertal female domestic pigs (Sus scrofa). Journal of neuroendocrinology. vol 17. issue 10. 2006-02-03. PMID:16159381. |
because there is evidence for the involvement of the vasopressin and serotonergic systems in the regulation of aggressive behaviour in male mammals, we sought differences using quantitative in situ hybridisation of vasopressin and serotonin 1a receptor (5-ht1a) mrna expression within specific brain regions of aggressive and nonaggressive prepubertal female pigs. |
2006-02-03 |
2023-08-12 |
Not clear |
| J E Holden, E Naleway Farah, Y Jeon. Stimulation of the lateral hypothalamus produces antinociception mediated by 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord dorsal horn. Neuroscience. vol 135. issue 4. 2006-01-11. PMID:16165284. |
these results suggest that the lateral hypothalamus modifies nociception in part by activating spinally projecting serotonin neurons that act at 5-ht1a, 5-ht1b, and 5-ht3 receptors in the dorsal horn. |
2006-01-11 |
2023-08-12 |
rat |
| E Calama, A V Ortíz de Urbina, A Morán, M L Martín, L San Romá. Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology. vol 32. issue 10. 2006-01-05. PMID:16173953. |
the effects of 5-ht were mimicked by 5-carboxamidotryptamine (a 5-ht1 receptor agonist) and l-694 247 (a selective 5-ht1d receptor agonist), but not by 8-hydroxy-2-dipropylaminotetralin (a 5-ht1a receptor agonist), cgs-12066b (a 5-ht1b receptor agonist), alpha-methyl-5-ht (a 5-ht2 receptor agonist), 1-(3-chlorophenyl) piperazine (a 5-ht2c receptor agonist) or 1-phenylbiguanide (a 5-ht3 receptor agonist). |
2006-01-05 |
2023-08-12 |
rat |
| G-J Huang, J Herber. The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16129565. |
depleting 5-ht with p-chlorophenylalanine (300 mg/kg initially followed by 100 mg/kg/day) or stimulating 5-ht1a receptors with 8-oh-dpat (1 mg/kg or 2 mg/kg, s.c. injections twice daily) for 14 days had no effect on cell proliferation as measured by ki-67 or brdu (5-bromo-3-deoxyuridine) immunocytochemistry in the dentate gyrus. |
2005-12-22 |
2023-08-12 |
rat |
| G-J Huang, J Herber. The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16129565. |
the 5-ht1a antagonist way-100635 (1.5 mg/kg/day also delivered by osmotic pump) by itself did not alter cell proliferation, confirming that reduced serotonin activity does not change proliferation, but blocked the effect of 8-oh-dpat. |
2005-12-22 |
2023-08-12 |
rat |
| Z Ma, R E Strecker, J T McKenna, M M Thakkar, R W McCarley, R Ta. Effects on serotonin of (-)nicotine and dimethylphenylpiperazinium in the dorsal raphe and nucleus accumbens of freely behaving rats. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16154286. |
finally, the 5-ht1a receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) was used to test whether the increases in 5-ht were depolarization-dependent. |
2005-12-22 |
2023-08-12 |
rat |
| Tom D Heightman, Laramie M Gaster, Sarah L Pardoe, Jean-Pierre Pilleux, Michael S Hadley, Derek N Middlemiss, Gary W Price, Claire Roberts, Claire M Scott, Jeannette M Watson, Laurie J Gordon, Vicky A Holland, Jenifer Powles, Graham J Riley, Tania O Stean, Brenda K Trail, Neil Upton, Nigel E Austin, Andrew D Ayrton, Tanya Coleman, Leanne Cutle. 8-Piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines: potent, selective, orally bioavailable 5-HT1 receptor ligands. Bioorganic & medicinal chemistry letters. vol 15. issue 19. 2005-12-20. PMID:16039851. |
the template was n-substituted to give a series of compounds showing binding to human cloned 5-ht1a, 5-ht1b and 5-ht1d receptors with pki's greater than 9 and selectivities up to 1000-fold against other serotonin, dopamine and adrenergic receptors. |
2005-12-20 |
2023-08-12 |
human |
| Margaret T T Wong-Riley, Qiuli Li. Neurochemical development of brain stem nuclei involved in the control of respiration. Respiratory physiology & neurobiology. vol 149. issue 1-3. 2005-12-20. PMID:16203213. |
several neurochemicals (glutamate, glycine receptors, choline acetyltransferase, serotonin, norepinephrine, and thyrotropin-releasing hormone) increase expression with age, while others (gaba, serotonin receptor 1a, substance p, neurokinin 1 receptor, and somatostatin) decrease their expression. |
2005-12-20 |
2023-08-12 |
rat |
| Qing-Shan Yan, Shi-Zhong Zheng, Mei-Jiang Feng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission. Brain research. vol 1060. issue 1-2. 2005-12-20. PMID:16212943. |
these ethanol-induced increases of the da release in the vta and the nacc were significantly attenuated by intra-tegmental infusion of sb 216641 (a 5-ht(1b) receptor antagonist), but not brl 15572 (a 5-ht(1d/1a) receptor antagonist) or way 100635 (a 5-ht1a receptor antagonist). |
2005-12-20 |
2023-08-12 |
rat |
| François Giuliano, Pierre Clémen. Physiology of ejaculation: emphasis on serotonergic control. European urology. vol 48. issue 3. 2005-12-13. PMID:15996810. |
in particular, 5-ht1a cerebral autoreceptors but also spinal 5-ht1b and, in a lesser extent, 5-ht2c receptors have been shown to mediate the effects of 5-ht on ejaculation. |
2005-12-13 |
2023-08-12 |
human |
| Manuella P Kaster, Adair R S Santos, Ana L S Rodrigue. Involvement of 5-HT1A receptors in the antidepressant-like effect of adenosine in the mouse forced swimming test. Brain research bulletin. vol 67. issue 1-2. 2005-12-13. PMID:16140163. |
the pre-treatment of mice with pcpa (100mg/kg, i.p., an inhibitor of serotonin synthesis, for four consecutive days), nan-190 (0.5mg/kg, i.p., a 5-ht1a receptor antagonist), pindolol (32 mg/kg, i.p., a 5-ht1a/1b receptor/beta-adrenoceptor antagonist) or way100635 (0.1 and 0.3mg/kg, s.c., a selective 5-ht1a receptor antagonist), but not with ketanserin (5mg/kg, i.p., a 5-ht2a/2c receptor antagonist), prevented the antidepressant-like effect of adenosine (10mg/kg, i.p.) |
2005-12-13 |
2023-08-12 |
mouse |
| J M Zanoveli, R L Nogueira, H Zangross. Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety. Behavioural pharmacology. vol 16. issue 7. 2005-11-30. PMID:16170231. |
chronic imipramine treatment sensitizes 5-ht1a and 5-ht 2 a receptors in the dorsal periaqueductal gray matter: evidence from the elevated t-maze test of anxiety. |
2005-11-30 |
2023-08-12 |
rat |
| J M Zanoveli, R L Nogueira, H Zangross. Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety. Behavioural pharmacology. vol 16. issue 7. 2005-11-30. PMID:16170231. |
chronic treatment with the anti-panic agent imipramine enhances the inhibitory effect on escape evoked by dpag electrical stimulation of intra-dpag administration of the 5-ht1a receptor agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) and the preferential 5-ht 2 a receptor agonist (+/-)-2,5-dimethoxy-4-iodoamphetamine hydrochloride (doi). |
2005-11-30 |
2023-08-12 |
rat |
| J M Zanoveli, R L Nogueira, H Zangross. Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety. Behavioural pharmacology. vol 16. issue 7. 2005-11-30. PMID:16170231. |
in the present study we further explore the hypothesis that sensitization of 5-ht1a and 5-ht 2 a receptors in the dpag is involved in the anti-panic effect of imipramine. |
2005-11-30 |
2023-08-12 |
rat |