| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi-Xi Wang, Xiao-Ning Kang, Yang Cao, De-Xiu Zheng, Ye-Ming Lu, Chun-Feng Pang, Zhi Wang, Bin Cheng, Yun Pen. Porphyromonas gingivalis induces depression via downregulating p75NTR-mediated BDNF maturation in astrocytes. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31299366. |
employing female mice treated with pg every other day for 4 weeks, we found that pg-mice showed obvious depression-like behavior, an increased number of activated astrocytes and decreased levels of mature brain derived neurotrophic factor (bdnf) and astrocytic p75ntr in the hippocampus. |
2020-08-14 |
2023-08-13 |
mouse |
| Ying Liu, Xing Zhang, Dandan Yan, Yiqi Wang, Na Wang, Yufan Liu, Aijun Tan, Xiaoyi Chen, Hong Ya. Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment. Toxicology and applied pharmacology. vol 393. 2020-08-13. PMID:32147541. |
chronic exposure to acr caused gait abnormality and cognitive dysfunction, which was associated with neuronal lesions, decrease in synapse associated proteins including synapsin i (syn1), synaptophysin (syp) and postsynaptic density protein 95 (psd95), neurogenesis suppression as shown by reduced brain derived neurotrophic factor (bdnf) and doublecortin (dcx) in the hippocampus and frontal cortex. |
2020-08-13 |
2023-08-13 |
rat |
| Yu-Hui You, Zhi-Qiang Qin, Huan-Li Zhang, Zhao-Hong Yuan, Xin Y. MicroRNA-153 promotes brain-derived neurotrophic factor and hippocampal neuron proliferation to alleviate autism symptoms through inhibition of JAK-STAT pathway by LEPR. Bioscience reports. vol 39. issue 6. 2020-08-07. PMID:30975733. |
microrna-153 promotes brain-derived neurotrophic factor and hippocampal neuron proliferation to alleviate autism symptoms through inhibition of jak-stat pathway by lepr. |
2020-08-07 |
2023-08-13 |
mouse |
| Ying Li, Tong Ren, Lanxi Xu, Ying Wang, Bingye Yang, Haohong Luo, Zhen Zeng, Yanan Zhang, Guicheng Du, Maoshu Zhu, Juan Zho. Propane-2-sulfonic acid octadec-9-enyl-amide, a novel peroxisome proliferator-activated receptors α and γ dual agonist, enhances hippocampal neurogenesis and neuroplasticity in rats with cerebral ischaemia. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31714482. |
in addition, n15 treatment markedly increased the newly mature neurons and enhanced the expression levels of growth-associated protein-43, synaptophysin, brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus. |
2020-07-31 |
2023-08-13 |
mouse |
| Xiao-Ying Lin, Ying Cui, Lei Wang, Wen Che. Chronic exercise buffers the cognitive dysfunction and decreases the susceptibility to seizures in PTZ-treated rats. Epilepsy & behavior : E&B. vol 98. issue Pt A. 2020-07-27. PMID:31377659. |
the levels of synaptic-related proteins including psd95 (postsynaptic density 95), synapsin, glua1, and bdnf (brain-derived neurotrophic factor) were measured to evaluate the hippocampal synaptic plasticity. |
2020-07-27 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. |
2020-07-21 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
this study was designed to investigate the effects of voluntary exercise and estrogen replacement on learning and memory deficits and reduction in hippocampal brain derived neurotrophic factor (bdnf) levels induced by ovariectomy. |
2020-07-21 |
2023-08-13 |
rat |
| Paula Bortoluzzi Canteiro, Daniel Casagrande Antero, Natalia Dos Santos Tramontin, Kellen Ugioni Simon, Carolini Mendes, Maria Eduarda Anastácio Borges Correa, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Insulin treatment protects the brain against neuroinflammation by reducing cerebral cytokines and modulating mitochondrial function. Brain research bulletin. vol 149. 2020-07-20. PMID:31002914. |
whereas the levels of brain-derived neurotrophic factor and beta-nerve growth factor in the hippocampus were not altered by lps, they were decreased in the cortex by insulin. |
2020-07-20 |
2023-08-13 |
rat |
| Jun Yamada, Shozo Jinn. Potential link between antidepressant-like effects of ketamine and promotion of adult neurogenesis in the ventral hippocampus of mice. Neuropharmacology. vol 158. 2020-07-20. PMID:31310776. |
the induction of expression of glun2b subunit of the nmdar, phosphorylated mammalian target of rapamycin (p-mtor), glua1 subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar), and brain derived neurotrophic factor (bdnf), by ketamine was greater in the ventral hippocampus than in the dorsal hippocampus. |
2020-07-20 |
2023-08-13 |
mouse |
| Shiva Bhandari, Pradeep K Shukla, Huda M Almabadi, Peeyush Sahay, Radhakrishna Rao, Prabhakar Pradha. Optical study of stress hormone-induced nanoscale structural alteration in brain using partial wave spectroscopic microscopy. Journal of biophotonics. vol 12. issue 6. 2020-07-14. PMID:30523668. |
the mrna for stress-related genes, brain-derived neurotrophic factor and tyrosine kinase-coupled receptor were also significantly reduced in the hippocampus of corticosterone-treated mice compared to that in control mice. |
2020-07-14 |
2023-08-13 |
mouse |
| Aanchal Aggarwal, Nishtha Sharma, Rajat Sandhir, Vikas Rish. S-nitrosoglutathione prevents cognitive impairment through epigenetic reprogramming in ovariectomised mice. Biochemical pharmacology. vol 168. 2020-07-06. PMID:31374192. |
reduced h3 acetylation triggers epigenetic repression of brain derived neurotrophic factor (bdnf) in cortex and hippocampus of ovx mice that may be responsible for neuronal damage and cognitive impairment. |
2020-07-06 |
2023-08-13 |
mouse |
| Tae-Kyung Han, Yea-Hyun Leem, Hee-Sun Ki. Treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor. Brain research. vol 1707. 2020-06-11. PMID:30496734. |
treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor. |
2020-06-11 |
2023-08-13 |
mouse |
| Benjamin H Singe. The vasculature in sepsis: delivering poison or remedy to the brain? The Journal of clinical investigation. vol 129. issue 4. 2020-06-08. PMID:30882365. |
these fragments directly sequester brain-derived neurotrophic factor and impair hippocampal long-term potentiation, an electrophysiologic correlate of memory. |
2020-06-08 |
2023-08-13 |
Not clear |
| Masaaki Tanichi, Kunio Shimizu, Shingo Enomoto, Minori Koga, Hiroyuki Toda, Masanori Nagamine, Eiji Suzuki, Masashi Nibuy. The effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder. European journal of pharmacology. vol 865. 2020-05-20. PMID:31654623. |
the effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder. |
2020-05-20 |
2023-08-13 |
rat |
| Vishnu N Thakare, Rajesh R Patil, Anupama A Suralkar, Valmik D Dhakane, Bhoomika M Pate. Protocatechuic acid attenuate depressive-like behavior in olfactory bulbectomized rat model: behavioral and neurobiochemical investigations. Metabolic brain disease. vol 34. issue 3. 2020-05-11. PMID:30848471. |
behavioral (ambulatory and rearing activity and immobility time), neurochemical [serotonin (5-ht), dopamine (da), norepinephrine (ne) and brain derived neurotrophic factor (bdnf) expression], biochemical (mda formation, il-6, tnf-α and antioxidants) changes in hippocampus and cerebral cortex along with serum corticosterone were investigated. |
2020-05-11 |
2023-08-13 |
rat |
| Woosuk Kim, Kyu Ri Hahn, Hyo Young Jung, Hyun Jung Kwon, Sung Min Nam, Jong Whi Kim, Joon Ha Park, Dae Young Yoo, Dae Won Kim, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Melatonin ameliorates cuprizone-induced reduction of hippocampal neurogenesis, brain-derived neurotrophic factor, and phosphorylation of cyclic AMP response element-binding protein in the mouse dentate gyrus. Brain and behavior. vol 9. issue 9. 2020-05-11. PMID:31429533. |
melatonin ameliorates cuprizone-induced reduction of hippocampal neurogenesis, brain-derived neurotrophic factor, and phosphorylation of cyclic amp response element-binding protein in the mouse dentate gyrus. |
2020-05-11 |
2023-08-13 |
mouse |
| Peng Zhang, Yinghua Yu, Yanfang Qin, Yuan Zhou, Renxian Tang, Qingling Wang, Xiangyang Li, Hongqin Wang, Katrina Weston-Green, Xu-Feng Huang, Kuiyang Zhen. Alterations to the microbiota-colon-brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice. The Journal of nutritional biochemistry. vol 65. 2020-04-20. PMID:30623851. |
further examination showed that hippocampal brain-derived neurotrophic factor was significantly decreased in dio mice (vs. dr). |
2020-04-20 |
2023-08-13 |
mouse |
| Jie Ruan, Li Liu, Xin Shan, Baomei Xia, Qiang F. Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling. Bioscience reports. vol 39. issue 4. 2020-04-20. PMID:30940777. |
the expressions of protein kinase a (pka), brain derived neurotrophic factor (bdnf), camp response element-binding protein (creb) in hippocampus were detected by western blot. |
2020-04-20 |
2023-08-13 |
mouse |
| Jiunn-Ming Sheen, Hong-Ren Yu, You-Lin Tain, Yu-Chieh Chen, Mei-Hsin Hsu, Li-Tung Huan. Young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: Effects of melatonin. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 78. 2020-04-03. PMID:31550497. |
young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: effects of melatonin. |
2020-04-03 |
2023-08-13 |
rat |
| Louisiana Carolina Ferreira de Meireles, Fernando Galvão, Deena M Walker, Laura Reck Cechinel, Ágnis Iohana de Souza Grefenhagen, Gisele Andrade, Roberta Passos Palazzo, Gisele Agustini Lovatel, Carla Giovanna Basso, Eric J Nestler, Ionara Rodrigues Siqueir. Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31250382. |
we aimed to investigate the effects of aging and different exercise modalities on aversive memory and epigenetic landscapes at brain-derived neurotrophic factor, cfos, and dna methyltransferase 3 alpha (bdnf, cfos, and dnmt3a, respectively) gene promoters in hippocampus of rats. |
2020-04-02 |
2023-08-13 |
rat |